EP0886115A2 - Dispositif pour l'entreposage cryogénique d'échantillons pharmaceutiques - Google Patents

Dispositif pour l'entreposage cryogénique d'échantillons pharmaceutiques Download PDF

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Publication number
EP0886115A2
EP0886115A2 EP98109629A EP98109629A EP0886115A2 EP 0886115 A2 EP0886115 A2 EP 0886115A2 EP 98109629 A EP98109629 A EP 98109629A EP 98109629 A EP98109629 A EP 98109629A EP 0886115 A2 EP0886115 A2 EP 0886115A2
Authority
EP
European Patent Office
Prior art keywords
bracket
edge
brackets
floors
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP98109629A
Other languages
German (de)
English (en)
Other versions
EP0886115A3 (fr
EP0886115B1 (fr
Inventor
Wolfgang Flohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Air Liquide Deutschland GmbH
Original Assignee
Messer Griesheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Messer Griesheim GmbH filed Critical Messer Griesheim GmbH
Publication of EP0886115A2 publication Critical patent/EP0886115A2/fr
Publication of EP0886115A3 publication Critical patent/EP0886115A3/fr
Application granted granted Critical
Publication of EP0886115B1 publication Critical patent/EP0886115B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00—Charging, supporting, and discharging the articles to be cooled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped

Definitions

  • the invention relates to a frame for holding containers for cryogenic Storage of pharmaceutical or biological samples.
  • the invention has for its object ampoule towers with a provide reliable and easy-to-use security system.
  • the device contains a box-shaped housing or a frame.
  • the Device contains carrying devices, e.g. B. shelves, support bracket, Rails or other supports.
  • the carrying devices are used to carry Containers (e.g. inserts, boxes, boxes, boxes or drawers).
  • the Containers are used to hold sample containers or packaging that contain biological or pharmaceutical material.
  • the sample containers are for example ampoules, cups, straws, multi-purpose cassettes, closable Tubes.
  • the device includes a security system that slips out prevented from containers from the device.
  • the security system of the device according to the invention contains at least a swivel bracket, the swivel axis to the side to the vertical Center line of the front lies.
  • the bracket can be horizontal and / or vertical Have crossbars, e.g. B. lattice door-like bracket.
  • Two brackets are advantageous if the inserts used are smaller than the front edge to have. This is the case, for example, with narrow ampoule boxes that stand side by side on an intermediate floor.
  • the swivel axis is preferably between the start of the leading edge (at one Side) and a quarter of the leading edge.
  • The is particularly preferably Swivel axis (with a bracket) measured near a quarter of the front edge from the side or front edge beginning, so that a bracket of a folding radius from about a quarter of the length of the leading edge to the midline of the front (Locking position or closed position) and to the side (unlocking or open position) can be folded.
  • the cutouts are, for example, in the middle of the Front edges of the floors.
  • two swiveling brackets they are For example, swivel axes on both sides of the front in the range of Beginning of leading edge to about a third of the leading edge (measured by both Sides), preferably in the area around a sixth of the leading edge.
  • the bracket radius is to be dimensioned so that the bracket of the Front (closed position) can be swung to the side (open position).
  • the stirrup radius does not have to be the same for all stirrups of a device. This is particularly advantageous with two or more stirrups.
  • the swivel axes of the bracket can then lie on one edge of the front.
  • the temples, the one Front half can also cover a common pivot axis have, e.g. B. nested hollow axes (temple ends) or with an axis (Temple end) connected temple.
  • the interconnected bracket with common pivot axis can also be connected by crossbars.
  • the shape of the recesses of the floors is advantageously designed so that the full Cross section of the ironing rod can be taken from the recess.
  • brackets are made from a rectangular bent rod (e.g. Round rod or rod with rectangular or square cross-section) made of metal like aluminum or stainless steel. Stainless steel is preferred as the material for the manufacture of the bracket.
  • the device is usually made of metal.
  • For Manufacturing can use metal in a wide variety of forms (Sheet, perforated sheet, grille, bars). Can also be used as a material for manufacturing Plastic (e.g. polycarbonate) can be used.
  • the device generally has one to 40 shelves.
  • the Intermediate shelves are usually made of metal (e.g. aluminum) and are in usually built in.
  • the security system advantageously consists of a swivel bracket and a step-like edge on the front edge of the floors.
  • the step-shaped Edge can be interrupted one or more times.
  • the height of the step-shaped Edge is dimensioned so that the slots are inserted into the device can. In general, the height of the step edge is in the range of 2 up to 5 mm.
  • Fig. 1 shows an example of a diagram of the device (ampoule tower, (1)) with swivel bracket (3).
  • the recesses (4) on the front edge of the upper (5), Bottom (6) and intermediate floors (7) serve to hold the ironing rod in closed, secured position.
  • the example of a device shown schematically in Fig. 1 is as follows further described. The following figures and explanations of the example are for better understanding, but are not intended as limitations to consider the subject of the invention.
  • the device has the outer dimensions: 640 mm high, 140 mm wide (front) and 166 mm deep.
  • the box-shaped housing on the back made of aluminum sheet with 2 mm sheet thickness carries 10 intermediate shelves (7), which extend over the entire width and Extend the depth of the housing.
  • the intermediate floors (7) are also made Made of aluminum sheet.
  • the stepped edge (2) of the front consists from a fold of the sheet and has a height of 3 mm.
  • Bracket (3) consists of a round rod made of stainless steel with a diameter of 5 mm.
  • the device advantageously contains a means for locking the pivotable Bracket.
  • the bracket can be in the closed position (secured) be fixed by a tab (9). This is illustrated by Fig. 2.
  • Fig. 2 shows a partial view of the upper part of a device with tab (9) for Locking the bracket (3).
  • the recess in the floors becomes Inclusion of the ironing bar and the step-like design (2) of the floors shown on the front edge.
  • Fig. 3 shows an example of a tab (9) as a resilient element made of metal is carried out with a semi-cylindrical deformation (10) for holding the swivel bracket and a bevel or rounding (11) on the front End of the tab.
  • the bevel (11) is used to guide the bracket, the under the tab is pivoted.
  • the bracket engages with the deformation (10).
  • the Fastening hole (12) at the rear end serves as a fastening point on Housing, e.g. B. by a riveted joint.
  • a double safety device with one or more swiveling brackets and through stepped front edges of the floors is particularly advantageous.
  • the coat hanger prevents the inserts from floating out in a secured state Ampoules or other sample containers when immersed in the liquid nitrogen cooling bath. Unlocking can be carried out very conveniently. After removal the device from the cold bath and the subsequent unlocking of the Bügels will slide out of inserts through the step-shaped Execution of the front edge of the floors additionally prevented.

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Warehouses Or Storage Devices (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Refrigerator Housings (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
EP98109629A 1997-06-18 1998-05-27 Dispositif pour l'entreposage cryogénique d'échantillons pharmaceutiques Expired - Lifetime EP0886115B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19725641 1997-06-18
DE19725641A DE19725641C2 (de) 1997-06-18 1997-06-18 Vorrichtung zur tiefkalten Lagerung von pharmazeutischen Proben

Publications (3)

Publication Number Publication Date
EP0886115A2 true EP0886115A2 (fr) 1998-12-23
EP0886115A3 EP0886115A3 (fr) 2000-10-11
EP0886115B1 EP0886115B1 (fr) 2006-05-03

Family

ID=7832767

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98109629A Expired - Lifetime EP0886115B1 (fr) 1997-06-18 1998-05-27 Dispositif pour l'entreposage cryogénique d'échantillons pharmaceutiques

Country Status (3)

Country Link
EP (1) EP0886115B1 (fr)
AT (1) ATE325319T1 (fr)
DE (2) DE19725641C2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1205248A3 (fr) * 2000-11-08 2003-04-23 Advanced Biotechnologies Limited Unité de stockage
KR101064321B1 (ko) * 2009-04-03 2011-09-14 주식회사 비스 액체질소용기 시료보관용 랙
CN107377030A (zh) * 2017-09-04 2017-11-24 安徽省农业科学院茶叶研究所 一种实验室用立体容量瓶放置架
CN114484967A (zh) * 2022-02-22 2022-05-13 中科康谱健康科技(山东)有限责任公司 一种用于生物样本的低温运输装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342489A1 (de) 1983-11-24 1985-06-05 Messer Griesheim Gmbh, 6000 Frankfurt Vorrichtung zur tiefkalten lagerung von biologischen oder pharmazeutischen proben

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1366451A (en) * 1920-06-29 1921-01-25 Eugene W Hawley Latching device for trunk-drawers
US3902603A (en) * 1974-07-01 1975-09-02 Banner Metals Retainer bar assembly for mail carrying rack
US4811999A (en) * 1984-02-02 1989-03-14 The Stanley Works Cabinet with pivoted locking outrigger
US4771900A (en) * 1987-04-09 1988-09-20 Nalge Company Storage rack for box-like container
US5168725A (en) * 1990-08-24 1992-12-08 National Health Guard, Inc. Cryogenic storage of perishable fluids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342489A1 (de) 1983-11-24 1985-06-05 Messer Griesheim Gmbh, 6000 Frankfurt Vorrichtung zur tiefkalten lagerung von biologischen oder pharmazeutischen proben
DE3342489C2 (de) 1983-11-24 1986-10-23 Messer Griesheim Gmbh, 6000 Frankfurt Vorrichtung zur tiefkalten Lagerung von biologischen oder pharmazeutischen Proben

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1205248A3 (fr) * 2000-11-08 2003-04-23 Advanced Biotechnologies Limited Unité de stockage
KR101064321B1 (ko) * 2009-04-03 2011-09-14 주식회사 비스 액체질소용기 시료보관용 랙
CN107377030A (zh) * 2017-09-04 2017-11-24 安徽省农业科学院茶叶研究所 一种实验室用立体容量瓶放置架
CN114484967A (zh) * 2022-02-22 2022-05-13 中科康谱健康科技(山东)有限责任公司 一种用于生物样本的低温运输装置

Also Published As

Publication number Publication date
DE19725641C2 (de) 1999-06-10
ATE325319T1 (de) 2006-06-15
DE59813523D1 (de) 2006-06-08
EP0886115A3 (fr) 2000-10-11
EP0886115B1 (fr) 2006-05-03
DE19725641A1 (de) 1998-12-24

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