EP0901406A1 - Appareil pour distribuer des liquides - Google Patents

Appareil pour distribuer des liquides

Info

Publication number
EP0901406A1
EP0901406A1 EP97927072A EP97927072A EP0901406A1 EP 0901406 A1 EP0901406 A1 EP 0901406A1 EP 97927072 A EP97927072 A EP 97927072A EP 97927072 A EP97927072 A EP 97927072A EP 0901406 A1 EP0901406 A1 EP 0901406A1
Authority
EP
European Patent Office
Prior art keywords
piston
net
cylinder
particular according
insert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97927072A
Other languages
German (de)
English (en)
Inventor
Alfred Von Schuckmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0901406A1 publication Critical patent/EP0901406A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/34—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
    • B05B1/3405—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
    • B05B1/341—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet
    • B05B1/3421—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber
    • B05B1/3431—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber the channels being formed at the interface of cooperating elements, e.g. by means of grooves
    • B05B1/3436—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with channels emerging substantially tangentially in the swirl chamber the channels being formed at the interface of cooperating elements, e.g. by means of grooves the interface being a plane perpendicular to the outlet axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/34—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl
    • B05B1/3405—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl
    • B05B1/341—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet
    • B05B1/3468—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with means for controlling the flow of liquid entering or leaving the swirl chamber
    • B05B1/3473—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to influence the nature of flow of the liquid or other fluent material, e.g. to produce swirl to produce swirl before discharging the liquid or other fluent material, e.g. in a swirl chamber upstream the spray outlet with means for controlling the flow of liquid entering or leaving the swirl chamber in response to liquid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00442—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means the means being actuated by the difference between the atmospheric pressure and the pressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0062—Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/007—Outlet valves actuated by the pressure of the fluid to be sprayed being opened by deformation of a sealing element made of resiliently deformable material, e.g. flaps, skirts, duck-bill valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B05B11/1004—Piston pumps comprising a movable cylinder and a stationary piston
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1059—Means for locking a pump or its actuation means in a fixed position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose

Definitions

  • the invention relates to a device for spreading
  • 00010 A device of this type is known from GB-2 262 138 A
  • 00011 knows. It is used for nasal application of a pharmaceutical
  • 00013 provides a cylinder containing the liquid
  • the cannula acts as a guide tube
  • the cylinder is in the form of a single portion
  • CONFIRMATION COPY 00036 to effect the delivery piston stroke; on the other hand 00037 for loading the device, i.e. inserting the disposable 00038 cartridge.
  • 00039 00040 A hand-operated pump atomizer results, for example, 00041 from GB-2 014 233 A.
  • 00042 00043 The object of the invention is to design a generic device 00044 in terms of handling and use, 00045 with the application of a powerful liquid jet. This problem is solved by the invention specified in claims 00048. 00049 00050 As a result of such a configuration, a generic 00051 device of increased utility value is achieved. The jet is more stable in 00052 and is deployed more powerfully, so that the 00053 target location, for example the nasal cavity, is also hit in the more distant 00054 areas.
  • 00075 storage container is designed to be a stationary component
  • 00094 forms a valve body, here that of an outlet valve
  • the mouthpiece part can be used as
  • the object of the invention is based below
  • FIG. 7 shows an enlargement on the mouthpiece side as 00167 Extract from FIG. 6, 00168 00169, FIG. 8, the insert piece connected to the wall of the pump cylinder by a cantilever, also 00171 if substantially enlarged in perspective and 00172, 00173 00174 Fig.
  • FIG. 9 shows a variant of the device according to the first exemplary embodiment in vertical section and provided with 00176 a protective cap, namely as a 00177 section through the narrow side of the device with a flat cross section and 00179 00180 Fig. 10 a half section through it 00182 00183
  • the device shown which is designated in its entirety with G 00184 te device for dispensing liquid, in particular 00185 medicinal liquid 1, comprises an area I and 00187 occupied by a 00186 so-called dispenser mechanism area II.
  • 00188 In between is a docking zone III.
  • the areas I 00189 and II extend coaxially, that is to say lying one behind the other in a longitudinal center axis xx.
  • Last 00206 res continues on the upper side of the transverse wall 7 in an intermediate chamber 9.
  • the inside diameter of ent ⁇ 00208 corresponds essentially to the pumping chamber 5.
  • the 00209 upper chamber edge forms a valve seat 10 for a cooperating exhaust valve 00210 VI of the pump P.
  • the valve body 11 of the exhaust valve VI is Siert according 00213 first embodiment as a separate component reali ⁇ 00,214th It extends axially directed from 00215 the top of the transverse wall 7 or the valve seat 00216 surface 10 to the underside of a ceiling 12 having the mouthpiece opening 00217 2 00218 00219
  • the ceiling 12 00220 is part of a counterhold 13 forming handle 00221 of the device G.
  • the handle formed to a plug or trunk 00222 continues, starting from the ceiling 12, in 00223 a tubular, stepped section 14.
  • the tubular section 14 or the counter 00238 stop 13 changes into a clear widening.
  • 00239 creates a substantially horizontally oriented shoulder 00240 16.
  • the index and middle fingers 00241 of an operating hand can be placed on it, while the 00242 thumb is guided against the underside of a base 17 of a docked liquid storage container 18, 00244 about the relative movement between cylinder 3 and piston 6
  • inlet valve VI forming valve so-called inlet valve VI forming valve.
  • 00278 inner stop sets the clear cross section 00279 of the riser pipe corresponding central bore 27. 00280 This establishes the flow connection to the valve chamber 23 00281.
  • 00282 00283 valve housing 15 and the carrier 25 inserted therein from below are located in an essentially 00285 cylindrical plug-in cavity 28 of a central connection socket 29.
  • the central connection socket 29 serves as a pump-side docking agent for one supply-side docking 00290 medium-setting threaded neck 30 of the bottle-shaped 00291 liquid storage container 18.
  • the 00292 end region of the connecting piece 29 00293 on the container side is thus comparable to a screw cap; it has a matching internal thread 00294 and can carry a 00295 sealing ring on the ceiling.
  • a locking engagement, as shown, which crosses the joints can serve as a rotation lock.
  • 00297 00298 In the upper end portion of the threaded neck 30 00299 protrudes peripherally tightly against a projection 31.
  • 00300 is axially hollowed out and reveals an annular gap 32 to the jacket wall of the 00302 riser 26 formed by a hose or the like.
  • 00303 00304 The annular gap 32 continues in the direction of the mouthpiece 00305 opening 2 into a cylindrical recess 33.
  • the 00306 connects coaxially and takes up the lower end of the carrier 25, which is stepped hollowed there in 00307.
  • 00308 00309
  • the lower end of the carrier 25 tapered 00310 rotationally symmetrically on the container side.
  • the lip 34 00311 thus created is supported in a sealing manner on the wall 00312 of the cylindrical recess 33 surrounding it.
  • 00313 00314 Said lip 34 is axially spaced from the step 00315 jump between the annular gap 32 and the recess 33.
  • Above 00316 half of the lip 34 there is a pressure compensation path 35.
  • 00317 The leads to the outside, so it has connection to the atmosphere 00318 re.
  • section 14 merges into a third cross section having a larger diameter 00326, 00327 realized on a correspondingly wall-recessed 00328 pot part 38 as a guide on the jacket wall of the connecting piece 29, (38) starting just below the 00330 shoulders 16.
  • 00331 00332 The lower front edge of the pot part 38 forms, as can be seen from 00333 Fig.
  • a stop limitation on a 00334 counter-stop 39 realized by the corresponding 00335 section of a hat-shaped continuation 40 of the 00336 connecting piece 29. It is the Obersei ⁇ 00337 te as a stop-forming element.
  • 00338 00339 having For receiving the a middle bright cross-sectional dimension 00340 section 14 is the upper cross-section corresponding to the spring ⁇ 00341 chamber 20 projecting end fortge ⁇ 00342 leads, so that the cross section smaller section may overflow to 00343 connecting pin 29th
  • the corresponding 00344 de cross-sectional reduction at 29 is denoted by 41.
  • 00345 00346 The hat-shaped continuation 40 merges into an annular wall 42 directed towards 00347.
  • 00348 there is an inside wall 43.
  • 00349 ken-like part 44 in the area below the shoulders 00350 16 of the counter 13 and is expediently closed 00351.
  • 00352 00353 ring wall 42 and wall 43 are used to form an overload 00354 Ü.
  • the latter consists of 00355 a holding flank 45, realized from the continued 00356-sided flank of a horizontally oriented groove on 00357 on the inside of the ring wall 42.
  • a chamfered 00359 or transversely convex section of a rib 46 is supported 00360 from.
  • the rib 46 is molded on the outside of the wall 43, to match a partial entry into the 00362 horizontal groove.
  • 00363 00364 When the device G is actuated with the application of a force 00365 in the direction of the arrow z, the resistance given by the overload threshold 00367 le Ü is only overcome from a certain pressure load 00366 onwards.
  • transverse channels 47 and swirl chamber 48 lie as depressions
  • valve chamber 51 that makes a comprehensive one
  • the medium can
  • 00453 stream It swirls in the released area.
  • the valve chamber 51 there could also be further closed by 00455 wall material, so 00456 that practically no unspent remaining amount 00457 can accumulate there.
  • 00458 00459 The device G according to the second exemplary embodiment (FIG. 5) 00460 is modified with regard to the insert 11 in that this insert 11 no longer occurs as a separate component, but is integrally formed with a component forming component. Nevertheless, 00464 it also functions here as a filling piece that prevents 00466 from forming significant residual quantities in the dispensing area. Specifically, it looks like this that the insert 11 is held over a bracket 56.
  • the 00468 arm-like cantilever is the bridge piece to a wall 57 00470 of the pump cylinder 3 which is extended in 00469 in the direction of the mouthpiece opening 2. It extends radially.
  • cover 12 and mouth opening 2 are realized on a 00473 pot-shaped stopper which is inserted upside down into a 00474 axially oriented plug-in receptacle 58 of wall 57 00475.
  • the insert 11 deflecting the liquid jet through head channels 47 several times 00478.
  • the reference numbers are used analogously to 00479.
  • the individual deflection points are labeled 00480 with a, b and c.
  • the deflection point a forms the inlet opening of the medium in 00481
  • b is the deflection point of the channel flank given by eccentric 00482 curvature connections on the 00483 channel flank there
  • c is finally the bottom region of the vortex 00485 axial direction of discharge 488 00485 chamber 48.
  • 00486 00487 Further modified Type of assignment of the spring 19. 00488 This is now right inside the pump chamber 00489 5.
  • the 00490 inlet valve 00491 V2 explained above, formed by a ball, while the outlet valve VI connected downstream of the upper terminal turn of the 00492 spring 19 is realized as a classic flutter valve with a corresponding 00494 escape space below the one there stationary insert parts 11, given by the valve chamber 51 there.
  • 00496 00497 In order to prevent the ball from exiting into the pump chamber 5, the free end of the lower terminal spring 00499 winding is web-like bent radially inward so that none 00500 the passage corresponding to the ball diameter is present.
  • 00501 00502 The docking agents are similar and should not be described in more detail here 00503.
  • both devices G can have a protective cap 59 covering at least 00510 the dispenser mechanism, ie covering area I 00511. In the second 00512 embodiment, this is provided with a clip 60, so that the device G there can be carried like a ballpoint pen 00514 etc. The other device G 00515 does not go beyond the popular pocket format.
  • 00516 00517 The protective cap according to the second embodiment is 00518 also used to cover the mouth of the 00519 mouthpiece opening 2.
  • plastic is used, taking into account that there is a functionally coordinated elasticity / flexibility 00523, for example to ensure that the 00524 lip 34 work like a hose or cuff valve
  • the second piston 62 has an axial length that
  • air passage opening 67 is preferably on the
  • the air passage opening 67 can be so practical

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Reciprocating Pumps (AREA)
  • Closures For Containers (AREA)

Abstract

L'invention concerne un appareil (G) pour distribuer des liquides (1), notamment des liquides médicamenteux, à partir d'une ouverture (2) du bec raccordée à un réservoir de liquide, par actionnement manuel d'un ensemble piston-cylindre (4) qui permet l'actionnement manuel uniquement après dépassement d'un seuil de surcharge (U). Cet appareil est pratique à utiliser et distribue un jet de liquide puissant par l'intermédiaire de la force d'un ressort de rappel, inférieure par rapport au seuil de surcharge (U), de l'ensemble piston-cylindre (4) conçu sous forme de pompe (P).
EP97927072A 1996-06-01 1997-05-28 Appareil pour distribuer des liquides Withdrawn EP0901406A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19622124 1996-06-01
DE19622124A DE19622124A1 (de) 1996-06-01 1996-06-01 Gerät zum Aufbringen von Flüssigkeiten
PCT/EP1997/002785 WO1997046324A1 (fr) 1996-06-01 1997-05-28 Appareil pour distribuer des liquides

Publications (1)

Publication Number Publication Date
EP0901406A1 true EP0901406A1 (fr) 1999-03-17

Family

ID=7795939

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97927072A Withdrawn EP0901406A1 (fr) 1996-06-01 1997-05-28 Appareil pour distribuer des liquides

Country Status (13)

Country Link
US (1) US6189739B1 (fr)
EP (1) EP0901406A1 (fr)
JP (1) JP2000511499A (fr)
CN (1) CN1220622A (fr)
AU (1) AU722098B2 (fr)
BR (1) BR9709503A (fr)
CA (1) CA2256008A1 (fr)
DE (1) DE19622124A1 (fr)
IL (1) IL126932A0 (fr)
NO (1) NO985610D0 (fr)
NZ (1) NZ333604A (fr)
PL (1) PL329938A1 (fr)
WO (1) WO1997046324A1 (fr)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19807921A1 (de) * 1998-02-25 1999-08-26 Pfeiffer Erich Gmbh & Co Kg Austrag-Steuerung für einen Medien-Spender
DE10050982A1 (de) * 2000-10-16 2002-04-18 Pfeiffer Erich Gmbh & Co Kg Spender und Verfahren zum Austragen von Medien
MXPA03003556A (es) 2000-10-23 2005-04-11 Medical Instill Tech Inc Distribuidor de fluido que tiene un frasco rigido y camara de aire interna flexible.
US7331944B2 (en) * 2000-10-23 2008-02-19 Medical Instill Technologies, Inc. Ophthalmic dispenser and associated method
EP1205198A1 (fr) * 2000-11-13 2002-05-15 The Technology Partnership Public Limited Company Distributeur à aérosol médical avec clapet d'admission d'air pour la régulation du vide pendant la délivrance
WO2002102443A1 (fr) * 2001-06-15 2002-12-27 Akzo Nobel N.V. Distributeur conçu pour administrer un fluide pharmaceutique
DE10131174A1 (de) * 2001-06-29 2003-01-16 Boehringer Ingelheim Pharma Vernebler zur Applikation von Flüssigkeiten auf die Augenoberfläche oder das Augenbindegewebe
GB0204829D0 (en) * 2002-03-01 2002-04-17 Glaxo Group Ltd A fluid dispensing device
GB0217798D0 (en) * 2002-08-01 2002-09-11 Glaxo Group Ltd A fluid dispensing device
ATE453421T1 (de) * 2002-05-09 2010-01-15 Glaxo Group Ltd Flüssigkeit abgebende vorrichtung
GB0210605D0 (en) * 2002-05-09 2002-06-19 Glaxo Group Ltd A fluid dispensing device
DE10229618A1 (de) 2002-06-25 2004-01-29 Ing. Erich Pfeiffer Gmbh Dosierpumpe, Verfahren zu ihrer Herstellung und Vorrichtung zur Durchführung des Verfahrens
DE10231749B4 (de) * 2002-07-13 2004-07-29 Aero Pump GmbH, Zerstäuberpumpen Saug-Druck-Pumpe zum Ausgeben einer Flüssigkeit aus einem Behältnis
GB0217802D0 (en) * 2002-08-01 2002-09-11 Glaxo Group Ltd A fluid dispensing device
US20080220107A1 (en) * 2002-09-03 2008-09-11 Pharmacure Health Care Ab Nasal spray apparatus
US6779689B2 (en) * 2003-01-21 2004-08-24 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Ovaloid dispensing container
GB0305583D0 (en) * 2003-03-11 2003-04-16 Glaxo Group Ltd A fluid dispensing device
FR2858568B1 (fr) * 2003-08-08 2006-09-15 Valois Sas Tete de pulverisation de produit liquide
CN1901958B (zh) * 2003-11-03 2011-03-09 葛兰素集团有限公司 流体分配装置
GB0405477D0 (en) * 2004-03-11 2004-04-21 Glaxo Group Ltd A fluid dispensing device
FR2862106B1 (fr) * 2003-11-07 2007-08-24 Valois Sas Pompe de distribution de produit fluide.
FR2862009B1 (fr) * 2003-11-07 2007-01-05 Valois Sas Tete de pulverisation de produit fluide et pompe de distribution comportant une telle tete.
GB0402690D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402693D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402697D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402695D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A metering pump system
GB0402691D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402692D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402694D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0507224D0 (en) * 2005-04-09 2005-05-18 Glaxo Group Ltd A fluid dispensing device
EP1714667A1 (fr) * 2005-04-20 2006-10-25 Medisize Schweiz AG Système de dosage avec un gouteur ou pulvérisateur et deux bras articulés et la méthode de fabrication
DE102005033771A1 (de) * 2005-07-15 2007-01-25 Saint-Gobain Calmar Gmbh Fluidaustragkopf
FR2892158B1 (fr) * 2005-10-17 2011-10-21 Valois Sas Pompe de distribution de produit fluide
GB2434753B (en) * 2005-11-22 2008-03-12 Bespak Plc Aerosol dispensing apparatus
GB2448838B (en) 2006-05-26 2009-02-11 Consort Medical Plc Improvements in or relating to dispensing apparatus
GB0610541D0 (en) 2006-05-26 2006-07-05 Bespak Plc Improvements in or relating to dispensing apparatus
GB0610666D0 (en) * 2006-05-30 2006-07-05 Glaxo Group Ltd Fluid dispenser
FR2905941B1 (fr) 2006-09-20 2011-02-11 Valois Sas Ensemble de distribution et distributeur de produit fluide comportant un tel ensemble de distribution
US20080302827A1 (en) * 2007-06-06 2008-12-11 Gerrish Donald L Spray dispenser
ES2606977T3 (es) * 2007-08-21 2017-03-28 Glaxo Group Limited Distribuidor de medicamentos
JP5191215B2 (ja) * 2007-11-19 2013-05-08 伸晃化学株式会社 点鼻薬容器
DE102007056380B4 (de) 2007-11-22 2020-06-25 WestRock Dispensing Systems Hemer GmbH Verschlusskappe für einen Austragkopf
US20090198199A1 (en) * 2008-02-01 2009-08-06 Drug Enhancement Company Of America, Llc Inert container and dispenser
US8757146B2 (en) 2008-02-07 2014-06-24 University Of Washington Through Its Center For Commercialization Circumferential aerosol device
DE102008027599A1 (de) 2008-06-10 2009-12-31 Meadwestvaco Calmar Gmbh Fluidaustragkopf
US8985401B2 (en) * 2008-06-10 2015-03-24 Meadwestvaco Calmar Gmbh Fluid discharge head
FR2933679B1 (fr) * 2008-07-10 2010-09-03 Valois Sas Dispositif de distribution de produit fluide.
WO2010025276A1 (fr) * 2008-08-27 2010-03-04 Drug Enhancement Company Of America, Llc Récipient et distributeur
GB2464282A (en) * 2008-10-08 2010-04-14 Archimedes Dev Ltd A device for administering a dose of opioid analgesic
WO2010076012A1 (fr) * 2009-01-02 2010-07-08 Boehringer Ingelheim International Gmbh Composant et inhalateur ainsi que procédé de fabrication d'un composant
FR2941933B1 (fr) * 2009-02-06 2016-02-12 Rexam Pharma La Verpilliere Dispositif pour la delivrance d'un produit comportant une pompe, comprenant une partie fixe et une partie mobile.
FR2946326B1 (fr) * 2009-06-04 2011-08-05 Rexam Dispensing Sys Bouton poussoir pour un systeme de distribution d'un liquide sous pression
PL3184136T3 (pl) 2010-03-25 2022-01-17 New Injection Systems Ltd Wstrzykiwacz
FR2961192B1 (fr) 2010-06-10 2012-07-27 Rexam Healthcare La Verpillier Dispositif de distribution de produit comprenant une pompe et un embout de distribution
RS55199B1 (sr) 2011-02-04 2017-01-31 Archimedes Dev Ltd Poboljšana posuda
JP6339371B2 (ja) 2011-03-03 2018-06-06 インペル ニューロファーマ インコーポレイテッド 経鼻薬物送達デバイス
CN103619485B (zh) 2011-05-09 2017-08-08 英倍尔药业股份有限公司 用于鼻腔药物递送的喷嘴
CN103420022B (zh) * 2012-05-16 2015-09-09 丁要武 按压式液体泵
BR112015011084A2 (pt) * 2012-11-16 2017-07-11 New Injection Systems Ltd conjunto de seringa pré-preenchida portátil
EP2922588B1 (fr) 2012-11-23 2019-02-06 New Injection Systems Ltd Système d'auto-injecteur
EP2991713B1 (fr) 2013-04-28 2019-06-19 Impel Neuropharma Inc. Récipient à dose unitaire médical
DE102013215599B4 (de) * 2013-08-07 2017-12-07 Aptar Radolfzell Gmbh Pumpeinrichtung und Spender für flüssige oder pastöse Medien
WO2015149921A1 (fr) 2014-03-31 2015-10-08 Boehringer Ingelheim Vetmedica Gmbh Inhalateur
US20220213299A1 (en) * 2014-03-31 2022-07-07 Boehringer Ingelheim Vetmedica Gmbh Inhaler
US11285277B2 (en) * 2014-03-31 2022-03-29 Boehringer Ingelheim Vetmedica Gmbh Inhaler
GB2528068B (en) * 2014-07-08 2017-02-15 Kind Consumer Ltd An inhaler
RU2017117411A (ru) * 2014-10-20 2018-11-22 Рик Пэкиджинг Системз Лимитед Насосное дозирующее устройство с выпускным клапаном
FR3027808B1 (fr) * 2014-11-04 2021-01-15 Aptar France Sas Tete de distribution nasale et dispositif de distribution de produit fluide comportant une telle tete.
MX2018002895A (es) 2015-09-10 2018-07-06 Impel Neuropharma Inc Dispositivo de administracion nasal en linea.
CN106214036A (zh) * 2016-08-11 2016-12-14 江门市爱威特电器有限公司 一种新型皂液泵
WO2019104205A1 (fr) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Dispositif intra-nasal avec tube plongeur
EP3713626A4 (fr) 2017-11-21 2021-08-18 Impel Neuropharma Inc. Dispositif intra-nasale avec interface d'entrée
EP3727530B1 (fr) 2017-12-22 2022-09-14 Softhale NV Chambre de pompage flexible
JP7317020B2 (ja) 2018-01-05 2023-07-28 インペル ファーマシューティカルズ インコーポレイテッド 精密嗅覚デバイスによるジヒドロエルゴタミンの鼻腔内送達
BR112020013750A8 (pt) 2018-01-05 2022-10-18 Impel Neuropharma Inc Dispensação intranasal de olanzapina por dispositivo olfativo de precisão
WO2019193568A1 (fr) * 2018-04-06 2019-10-10 Id Packaging Inc. Pompe de distribution et son procédé de fabrication
CN112312951A (zh) 2018-04-12 2021-02-02 火箭科学健康公司 鼻内药物输送装置、系统和过程
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
US10940493B2 (en) * 2018-07-26 2021-03-09 S. C. Johnson & Son, Inc. Actuator and nozzle insert for dispensing systems
EP3856422B1 (fr) * 2018-09-27 2023-04-12 SHL Medical AG Mécanisme d'activation pour distributeur d'aérosol
WO2020142206A1 (fr) 2019-01-03 2020-07-09 Impel Neuropharma, Inc. Dispositif d'administration de médicament par voie nasale
WO2020212313A1 (fr) * 2019-04-15 2020-10-22 Softhale Nv Vanne améliorée
PL3738677T3 (pl) * 2019-05-16 2022-03-28 Brill Engines, S.L. Urządzenie odpowiednie do dozowania substancji ciekłych
CN114025816A (zh) 2019-05-17 2022-02-08 英倍尔药业股份有限公司 一次性鼻腔给送装置
KR20220035480A (ko) * 2019-07-18 2022-03-22 지비 디벨롭먼트 액체 디스펜서
KR102227941B1 (ko) * 2019-07-30 2021-03-15 조승현 휴대용 수소수 미스트 분사기
WO2021042037A2 (fr) * 2019-08-30 2021-03-04 Noble International, Llc Dispositif d'entraînement pour médicament nasal
WO2022049072A1 (fr) * 2020-09-01 2022-03-10 Janssen Pharmaceutica Nv Dispositifs d'administration de médicament avec verrouillage avant l'administration du médicament
KR20230145574A (ko) 2021-01-17 2023-10-17 에스.씨. 존슨 앤 선 인코포레이티드 에어로졸 스프레이, 에어로졸 스프레이 생성 방법,및 에어로졸 디스펜싱 시스템
US12542072B2 (en) 2021-02-23 2026-02-03 Noble International, Llc Injection training device
US11759586B1 (en) * 2022-04-13 2023-09-19 Ferrer Medical Innovations, LLC Nasal spray bottle with improved nozzle and system of application
FR3146289B1 (fr) * 2023-03-02 2025-08-22 Aptar France Sas Dispositif de distribution de produit fluide

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083476A (en) 1973-11-30 1978-04-11 Boehringer Ingelheim Gmbh Snap device for manually actuated liquid-atomizing pumps
IT1092596B (it) 1978-02-09 1985-07-12 Ruscitti Tommaso Pompetta a mano per dispensare liquidi micronizzati a pressione prestabilita
US4410107A (en) 1981-12-18 1983-10-18 Corsette Douglas Frank Liquid dispensing pump
EP0165949B1 (fr) 1983-12-14 1989-03-22 SCHOTTE, Werner Pompe pulverisatrice avec raccord de recipient
DE8711365U1 (de) 1987-08-21 1988-12-22 Schotte GmbH, 5870 Hemer Drallzerstäuberpumpe
FR2649323B1 (fr) 1989-07-04 1995-06-30 Valois Dispositif de projection et de pulverisation d'une dose d'un produit divisable
DE4008070A1 (de) * 1990-03-14 1991-09-19 Pfeiffer Erich Gmbh & Co Kg Austragkopf fuer medien-austragvorrichtungen
GB9007813D0 (en) 1990-04-06 1990-06-06 Bespak Plc Dispensing device
DE4016126A1 (de) 1990-04-17 1991-10-24 Coster Tecnologie Speciali Spa Vorrichtung zur transnasalen oder oralen verabreichung von medikamenten o. dgl.
FR2665848B1 (fr) 1990-08-17 1992-10-30 Aerosols & Bouchage Buses a clapet incorpore.
US5331954A (en) 1990-12-21 1994-07-26 Novo Nordisk A/S Device for nasal delivery of liquid medications
IT1249600B (it) 1991-02-21 1995-03-09 Elettro Plastica Spa Erogatore nasale di sostanze farmaceutiche nebulizzate
DE4110303A1 (de) * 1991-03-28 1992-10-01 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
US5181635A (en) * 1991-05-31 1993-01-26 Calmar Inc. Liquid pump dispenser having a stationary spout
DE9107249U1 (de) * 1991-06-12 1992-10-15 Ortner, Georg, 5000 Köln Parfümspender
GB9125699D0 (en) 1991-12-03 1992-01-29 Glaxo Group Ltd Device
US5351863A (en) * 1993-03-08 1994-10-04 Dupont Industries, Inc. Manually-operated dispensing pump
GB9408276D0 (en) 1994-04-26 1994-06-15 Bespak Plc Dispensing pump
DE4417486A1 (de) * 1994-05-19 1995-11-23 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
DE19533979A1 (de) 1995-09-14 1997-03-20 Alfred Von Schuckmann Gerät zur dosierten, luftgetragenen Ausgabe von Substanzen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9746324A1 *

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CN1220622A (zh) 1999-06-23
JP2000511499A (ja) 2000-09-05
NO985610L (no) 1998-12-01
DE19622124A1 (de) 1997-12-04
AU722098B2 (en) 2000-07-20
IL126932A0 (en) 1999-09-22
BR9709503A (pt) 1999-08-10
WO1997046324A1 (fr) 1997-12-11
NZ333604A (en) 2000-04-28
US6189739B1 (en) 2001-02-20
AU3169397A (en) 1998-01-05
PL329938A1 (en) 1999-04-26
CA2256008A1 (fr) 1997-12-11
NO985610D0 (no) 1998-12-01

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