EP0904103A4 - GLUTAMYL tRNA SYNTHETASE POLYNUCLEOTIDEN UND POLYPEPTIDEN - Google Patents

GLUTAMYL tRNA SYNTHETASE POLYNUCLEOTIDEN UND POLYPEPTIDEN

Info

Publication number
EP0904103A4
EP0904103A4 EP97918782A EP97918782A EP0904103A4 EP 0904103 A4 EP0904103 A4 EP 0904103A4 EP 97918782 A EP97918782 A EP 97918782A EP 97918782 A EP97918782 A EP 97918782A EP 0904103 A4 EP0904103 A4 EP 0904103A4
Authority
EP
European Patent Office
Prior art keywords
polynucleotides
polypeptides
trna synthetase
synthetase family
glutamyl trna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97918782A
Other languages
English (en)
French (fr)
Other versions
EP0904103A1 (de
Inventor
Elizabeth Jane Lawlor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Ltd
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, SmithKline Beecham Corp filed Critical SmithKline Beecham Ltd
Publication of EP0904103A1 publication Critical patent/EP0904103A1/de
Publication of EP0904103A4 publication Critical patent/EP0904103A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP97918782A 1996-04-18 1997-04-18 GLUTAMYL tRNA SYNTHETASE POLYNUCLEOTIDEN UND POLYPEPTIDEN Withdrawn EP0904103A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9607992.6A GB9607992D0 (en) 1996-04-18 1996-04-18 Novel compounds
GB9607992 1996-04-18
PCT/US1997/006753 WO1997038718A1 (en) 1996-04-18 1997-04-18 Novel compounds

Publications (2)

Publication Number Publication Date
EP0904103A1 EP0904103A1 (de) 1999-03-31
EP0904103A4 true EP0904103A4 (de) 1999-11-03

Family

ID=10792236

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97918782A Withdrawn EP0904103A4 (de) 1996-04-18 1997-04-18 GLUTAMYL tRNA SYNTHETASE POLYNUCLEOTIDEN UND POLYPEPTIDEN

Country Status (4)

Country Link
EP (1) EP0904103A4 (de)
JP (1) JP2000509261A (de)
GB (1) GB9607992D0 (de)
WO (1) WO1997038718A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0964921A4 (de) * 1997-11-05 2002-01-23 Smithkline Beecham Corp Neue ers aus streptococcus
US6891083B1 (en) 1998-11-10 2005-05-10 Omolayo O. Famodu Plant aminoacyl-tRNA synthetases
EP1131453A2 (de) * 1998-11-10 2001-09-12 E.I. Du Pont De Nemours And Company Aminoacyl-trna synthetasen aus pflanzen
CN1297999A (zh) * 1999-11-24 2001-06-06 上海博容基因开发有限公司 一种新的多肽——人谷氨酰转移核糖核酸合成酶58和编码这种多肽的多核苷酸
BRPI0922132A2 (pt) 2008-12-03 2018-10-23 Protea Vaccine Tech Ltd fragmentos glutamil trna sintetase (gts).
US20120076813A1 (en) * 2008-12-03 2012-03-29 Ben Gurion University Of The Negev Research And De Velopment Authority USES OF GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009927A2 (en) * 1993-10-06 1995-04-13 Zeneca Limited Assay procedure and application in identification of herbicides
WO1997043303A1 (en) * 1996-05-14 1997-11-20 Smithkline Beecham Corporation Novel compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009927A2 (en) * 1993-10-06 1995-04-13 Zeneca Limited Assay procedure and application in identification of herbicides
WO1997043303A1 (en) * 1996-05-14 1997-11-20 Smithkline Beecham Corporation Novel compounds

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DORION ET AL: "Synthesis of an inhibitor of glutamyl-tRNA synthetase", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 3, no. 12, 1993, pages 2699 - 2702, XP000670101 *
KRON ET AL.: "An immunodominant antigen of Brugia malayi is an aspariginyl-tRNA synthetase", FEBS LETTERS, vol. 374, 1995, pages 122 - 124, XP002028777 *
LASKE ET AL.: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part I. The antibacterial effect", ARCHIV. PHARM. (WEINHEIM), vol. 322, 1989, pages 847 - 852, XP002113352 *
LASKE ET AL: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part II. The antileukemic effect", ARCHIV DER PHARMAZIE, vol. 322, no. 12, December 1989 (1989-12-01), pages 857 - 862, XP002106398, ISSN: 0365-6233 *
See also references of WO9738718A1 *
VON DER HAAR: "Target directed drug synthesis: the aminoacyl-tRNA synthetases as possible targets", ANGEWANDTE CHEMIE, vol. 20, no. 3, March 1981 (1981-03-01), pages 217 - 223, XP002112772 *

Also Published As

Publication number Publication date
EP0904103A1 (de) 1999-03-31
JP2000509261A (ja) 2000-07-25
GB9607992D0 (en) 1996-06-19
WO1997038718A1 (en) 1997-10-23

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Legal Events

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