EP0906330A4 - ISOLEUCYL-tRNS-SYNTHEASE VON STREPTOCOCCUS PNEUMONIAL - Google Patents
ISOLEUCYL-tRNS-SYNTHEASE VON STREPTOCOCCUS PNEUMONIALInfo
- Publication number
- EP0906330A4 EP0906330A4 EP97918744A EP97918744A EP0906330A4 EP 0906330 A4 EP0906330 A4 EP 0906330A4 EP 97918744 A EP97918744 A EP 97918744A EP 97918744 A EP97918744 A EP 97918744A EP 0906330 A4 EP0906330 A4 EP 0906330A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- streptococcus pneumoniae
- trna synthetase
- isoleucyl trna
- isoleucyl
- synthetase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000029793 Isoleucine-tRNA ligase Human genes 0.000 title 1
- 101710176147 Isoleucine-tRNA ligase, cytoplasmic Proteins 0.000 title 1
- 101710149031 Probable isoleucine-tRNA ligase, cytoplasmic Proteins 0.000 title 1
- 241000193998 Streptococcus pneumoniae Species 0.000 title 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9608000 | 1996-04-18 | ||
| GBGB9608000.7A GB9608000D0 (en) | 1996-04-18 | 1996-04-18 | Novel compounds |
| PCT/US1997/006551 WO1997039011A1 (en) | 1996-04-18 | 1997-04-18 | STREPTOCOCCUS PNEUMONIAE ISOLEUCYL tRNA SYNTHETASE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0906330A1 EP0906330A1 (de) | 1999-04-07 |
| EP0906330A4 true EP0906330A4 (de) | 1999-10-20 |
Family
ID=10792244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP97918744A Withdrawn EP0906330A4 (de) | 1996-04-18 | 1997-04-18 | ISOLEUCYL-tRNS-SYNTHEASE VON STREPTOCOCCUS PNEUMONIAL |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0906330A4 (de) |
| JP (1) | JP2000509260A (de) |
| GB (1) | GB9608000D0 (de) |
| WO (1) | WO1997039011A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329168B1 (en) | 1996-04-18 | 2001-12-11 | Smithkline Beecham Corp. | Streptococcus pneumoniae isoleucyl tRNA synthetase |
| EP0909819A1 (de) * | 1997-10-17 | 1999-04-21 | Smithkline Beecham Corporation | Streptococcus pneumoniae Isoleucyl tRNA synthetase (IleS)[6.1.1.5.] |
| NZ504669A (en) | 1997-11-25 | 2002-11-26 | Gen Hospital Corp | Virulence-associated nucleic acid sequences and uses in identification of anti-virulence agents |
| US7112716B2 (en) | 2000-04-06 | 2006-09-26 | The General Hospital Corporation | Methods for screening and identifying host pathogen defense genes |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994028139A1 (en) * | 1993-05-28 | 1994-12-08 | Massachusetts Institute Of Technology | tRNA BINDING-DEPENDENT INHIBITION OF MICROBIAL PATHOGEN GROWTH |
| WO1995009927A2 (en) * | 1993-10-06 | 1995-04-13 | Zeneca Limited | Assay procedure and application in identification of herbicides |
| EP0786519A2 (de) * | 1996-01-05 | 1997-07-30 | Human Genome Sciences, Inc. | Polynukleotide und Sequenzen aus Staphylococcus aureus |
| WO1998018931A2 (en) * | 1996-10-31 | 1998-05-07 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
| WO1998019689A1 (en) * | 1996-11-01 | 1998-05-14 | Smithkline Beecham Corporation | Novel coding sequences |
-
1996
- 1996-04-18 GB GBGB9608000.7A patent/GB9608000D0/en active Pending
-
1997
- 1997-04-18 JP JP9537417A patent/JP2000509260A/ja active Pending
- 1997-04-18 WO PCT/US1997/006551 patent/WO1997039011A1/en not_active Ceased
- 1997-04-18 EP EP97918744A patent/EP0906330A4/de not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994028139A1 (en) * | 1993-05-28 | 1994-12-08 | Massachusetts Institute Of Technology | tRNA BINDING-DEPENDENT INHIBITION OF MICROBIAL PATHOGEN GROWTH |
| WO1995009927A2 (en) * | 1993-10-06 | 1995-04-13 | Zeneca Limited | Assay procedure and application in identification of herbicides |
| EP0786519A2 (de) * | 1996-01-05 | 1997-07-30 | Human Genome Sciences, Inc. | Polynukleotide und Sequenzen aus Staphylococcus aureus |
| WO1998018931A2 (en) * | 1996-10-31 | 1998-05-07 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
| WO1998019689A1 (en) * | 1996-11-01 | 1998-05-14 | Smithkline Beecham Corporation | Novel coding sequences |
Non-Patent Citations (5)
| Title |
|---|
| BUDAVARI ET AL.: "The Merck Index, 12th ed.", 1996, MERCK & CO., INC., WHITEHOUSE STATION, NJ, XP002113499 * |
| HONG ET AL.: "An isoleucyl-tRNA synthetase gene from Campylobacter jejuni", MICROBIOLOGY, vol. 141, no. 10, October 1995 (1995-10-01), pages 2561 - 2567, XP002112692 * |
| LASKE ET AL.: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part I. The antibacterial effect", ARCHIV DER PHARMAZIE, vol. 322, no. 12, December 1989 (1989-12-01), pages 847 - 852, XP002113352 * |
| LASKE ET AL: "Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part II. The antileukemic effect", ARCHIV DER PHARMAZIE, vol. 322, no. 12, December 1989 (1989-12-01), pages 857 - 862, XP002106398, ISSN: 0365-6233 * |
| See also references of WO9739011A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0906330A1 (de) | 1999-04-07 |
| JP2000509260A (ja) | 2000-07-25 |
| WO1997039011A1 (en) | 1997-10-23 |
| GB9608000D0 (en) | 1996-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19981118 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE CH DE DK FR GB IT LI NL |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 19990907 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): BE CH DE DK FR GB IT LI NL |
|
| RIC1 | Information provided on ipc code assigned before grant |
Free format text: 6C 12N 15/52 A, 6C 12N 9/00 B, 6C 07K 16/40 B, 6C 12Q 1/68 B, 6A 61K 38/53 B, 6A 61K 39/09 B |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
| 18W | Application withdrawn |
Withdrawal date: 20020201 |