EP0909558A3 - Ophthalmische Lösung enthaltend ein Chromanderivat - Google Patents

Ophthalmische Lösung enthaltend ein Chromanderivat Download PDF

Info

Publication number: EP0909558A3
Authority: EP; European Patent Office
Prior art keywords: ophthalmic solution; active ingredient; chroman; derivative containing; chroman derivative
Prior art date: 1997-08-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP98115893A

Other languages

English (en)

French (fr)

Other versions

EP0909558A2 (de

Inventor

Atsutoshi c/o Santen Pharmaceutical Co. Ltd Ota

Mitsuaki c/o Santen Pharmaceutical Co. LTD Kuwano

Koichi c/o Santen Pharmaceutical Co. LTD. Takada

Chihiro c/o Sanwa Kagaku Kenkyusho Co. Ltd. Hibi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Santen Pharmaceutical Co Ltd

Sanwa Kagaku Kenkyusho Co Ltd

Original Assignee

Santen Pharmaceutical Co Ltd

Sanwa Kagaku Kenkyusho Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-29

Filing date

1998-08-24

Publication date

1999-10-27

1998-08-24 Application filed by Santen Pharmaceutical Co Ltd, Sanwa Kagaku Kenkyusho Co Ltd filed Critical Santen Pharmaceutical Co Ltd

1999-04-21 Publication of EP0909558A2 publication Critical patent/EP0909558A2/de

1999-10-27 Publication of EP0909558A3 publication Critical patent/EP0909558A3/de

Status Withdrawn legal-status Critical Current

Links

229940054534 ophthalmic solution Drugs 0.000 title abstract 3
239000002997 ophthalmic solution Substances 0.000 title abstract 3
VZWXIQHBIQLMPN-UHFFFAOYSA-N chromane Chemical class C1=CC=C2CCCOC2=C1 VZWXIQHBIQLMPN-UHFFFAOYSA-N 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 3
WAAPEIZFCHNLKK-UFBFGSQYSA-N (2s,4s)-6-fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide Chemical compound C([C@H](OC1=CC=C(F)C=C11)C(=O)N)[C@@]21NC(=O)NC2=O WAAPEIZFCHNLKK-UFBFGSQYSA-N 0.000 abstract 2
229920003174 cellulose-based polymer Polymers 0.000 abstract 2
230000035515 penetration Effects 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 1
239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
230000003204 osmotic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Inorganic Chemistry (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

EP98115893A 1997-08-29 1998-08-24 Ophthalmische Lösung enthaltend ein Chromanderivat Withdrawn EP0909558A3 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP23399097		1997-08-29
JP23399097		1997-08-29
JP233990/97		1997-08-29

Publications (2)

Publication Number	Publication Date
EP0909558A2 EP0909558A2 (de)	1999-04-21
EP0909558A3 true EP0909558A3 (de)	1999-10-27

Family

ID=16963824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP98115893A Withdrawn EP0909558A3 (de)	1997-08-29	1998-08-24	Ophthalmische Lösung enthaltend ein Chromanderivat

Country Status (5)

Country	Link
EP (1)	EP0909558A3 (de)
KR (1)	KR19990023971A (de)
CN (1)	CN1215591A (de)
CA (1)	CA2246224A1 (de)
TW (1)	TW422705B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2527712C (en) *	2003-06-13	2014-08-05	Alcon, Inc.	Ophthalmic compositions containing a synergistic combination of two polymers
WO2005039574A1 (ja) *	2003-10-24	2005-05-06	Santen Pharmaceutical Co., Ltd.	角結膜障害の治療剤
IL168603A (en) *	2005-05-16	2011-05-31	Resdevco Res And Dev Co	Pharmaceutical or cosmetic composition for the prevention and treatment of irritation of mucous cells or skin cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0437025A2 (de) *	1990-01-12	1991-07-17	Sanwa Kagaku Kenkyusho Co., Ltd.	Aldosereduktasehemmer enthaltende Zubereitungen zur Behandlung von Geschwüren
JPH03271291A (ja) *	1990-03-19	1991-12-03	Sanwa Kagaku Kenkyusho Co Ltd	点眼剤
EP0719556A2 (de) *	1994-12-28	1996-07-03	Sanwa Kagaku Kenkyusho Co., Ltd.	Mittel zur Behandlung von Keratopathie

1998
- 1998-08-24 EP EP98115893A patent/EP0909558A3/de not_active Withdrawn
- 1998-08-27 CN CN98119985A patent/CN1215591A/zh active Pending
- 1998-08-27 CA CA002246224A patent/CA2246224A1/en not_active Abandoned
- 1998-08-28 TW TW087114277A patent/TW422705B/zh active
- 1998-08-28 KR KR1019980035094A patent/KR19990023971A/ko not_active Withdrawn

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0437025A2 (de) *	1990-01-12	1991-07-17	Sanwa Kagaku Kenkyusho Co., Ltd.	Aldosereduktasehemmer enthaltende Zubereitungen zur Behandlung von Geschwüren
JPH03271291A (ja) *	1990-03-19	1991-12-03	Sanwa Kagaku Kenkyusho Co Ltd	点眼剤
EP0719556A2 (de) *	1994-12-28	1996-07-03	Sanwa Kagaku Kenkyusho Co., Ltd.	Mittel zur Behandlung von Keratopathie

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 116, no. 18, 4 May 1992, Columbus, Ohio, US; abstract no. 181154, XP002110823 *

Also Published As

Publication number	Publication date
EP0909558A2 (de)	1999-04-21
CN1215591A (zh)	1999-05-05
CA2246224A1 (en)	1999-02-28
TW422705B (en)	2001-02-21
KR19990023971A (ko)	1999-03-25

Legal Events

Date	Code	Title	Description
1999-03-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1999-04-21	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
1999-04-21	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
1999-09-10	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
1999-10-27	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
1999-10-27	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2000-05-10	17P	Request for examination filed	Effective date: 20000306
2000-07-05	AKX	Designation fees paid	Free format text: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-07-07	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
2000-08-23	18W	Application withdrawn	Withdrawal date: 20000629

Publication	Publication Date	Title
CA2242986A1 (en)	1997-07-24	Sustained release drug formulations
WO1997028827A1 (fr)	1997-08-14	Composition ophtalmique possedant une viscosite adaptee
AU3470600A (en)	2000-08-01	Compositions and methods for drug delivery
IL157531A0 (en)	2004-03-28	Erodible polymers for injection
WO1997048385A3 (en)	1998-02-19	Controlled release tablet
CA2193129A1 (en)	1996-01-25	Transdermal drug delivery system
CA2347925A1 (en)	2000-05-04	Propofol composition
CA2243201A1 (en)	1999-01-15	Process for producing sustained-release preparation
KR960028918A (ko)	1996-08-17	국소용 약제학적 조성물
CA2011956A1 (en)	1991-09-12	Sodium hyaluronate composition
WO1996026718A3 (en)	1996-10-10	Controlled release tablet
AU2001266033A1 (en)	2001-12-11	Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base
AU2494097A (en)	1998-01-08	Preparation of aqueous polymer dispersions of low viscosity with polymer volume concentrations of at least 50 per cent
AU2002357972A1 (en)	2003-07-09	Heparin-containing ophthalmic agent
AU6086099A (en)	2000-04-10	N-acylvanillinamide derivatives capable of activating peripheral cannabinoid receptors
IL131663A0 (en)	2001-01-28	Ophthalmic composition
WO2000074649A3 (en)	2002-01-17	Ophthalmic histamine compositions and uses thereof
ES2080031T3 (es)	1999-05-01	Preparacion oftalmologica.
AU1413799A (en)	1999-06-28	Non-aqueous, heterogeneous polymerization process and reaction product obtained thereby
AU5980200A (en)	2001-01-22	Ophthalmic compositions in form of aqueous gels
AU6926394A (en)	1994-12-12	Compositions in the form of solid solutions
CA2090911A1 (en)	1994-01-08	Aqueous pharmaceutical formulations of sodium cromoglycate
CA2174707A1 (en)	1996-10-25	Chromone derivatives as nk1 and substance p antagonists
CA2407325A1 (en)	2001-11-08	Low ionic strength ophthalmic compositions
EP0580871A4 (de)	1994-11-30	Wasserlösliches cellulosederivat und bioverträgliches material.