EP0918788A4 - Brca1 zusammensetzungen und methoden zur diagnose und behandlung von brustkrebs - Google Patents

Brca1 zusammensetzungen und methoden zur diagnose und behandlung von brustkrebs

Info

Publication number
EP0918788A4
EP0918788A4 EP97933344A EP97933344A EP0918788A4 EP 0918788 A4 EP0918788 A4 EP 0918788A4 EP 97933344 A EP97933344 A EP 97933344A EP 97933344 A EP97933344 A EP 97933344A EP 0918788 A4 EP0918788 A4 EP 0918788A4
Authority
EP
European Patent Office
Prior art keywords
brca1
diagnostic
compositions
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97933344A
Other languages
English (en)
French (fr)
Other versions
EP0918788A1 (de
Inventor
Wen-Hwa Lee
Yumay Chen
Chi-Fen Chen
Phang-Lang Chen
Andrew A Farmer
Diane C Jones
D Craig Allred
C Kent Osborne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
University of Texas at Austin
Original Assignee
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, University of Texas at Austin filed Critical University of Texas System
Publication of EP0918788A1 publication Critical patent/EP0918788A1/de
Publication of EP0918788A4 publication Critical patent/EP0918788A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP97933344A 1996-07-08 1997-07-08 Brca1 zusammensetzungen und methoden zur diagnose und behandlung von brustkrebs Withdrawn EP0918788A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1586396P 1996-07-08 1996-07-08
US15863P 1996-07-08
PCT/US1997/011946 WO1998001460A1 (en) 1996-07-08 1997-07-08 Brca1 compositions and methods for the diagnosis and treatment of breast cancer

Publications (2)

Publication Number Publication Date
EP0918788A1 EP0918788A1 (de) 1999-06-02
EP0918788A4 true EP0918788A4 (de) 2002-02-13

Family

ID=21774065

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97933344A Withdrawn EP0918788A4 (de) 1996-07-08 1997-07-08 Brca1 zusammensetzungen und methoden zur diagnose und behandlung von brustkrebs

Country Status (7)

Country Link
EP (1) EP0918788A4 (de)
JP (1) JP2002513272A (de)
KR (1) KR20000023600A (de)
AU (1) AU736210B2 (de)
CA (1) CA2259154A1 (de)
NZ (1) NZ333635A (de)
WO (1) WO1998001460A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998005968A1 (en) 1996-08-02 1998-02-12 The Wistar Institute Of Anatomy And Biology Brca1 associated protein (bap-1) and uses therefor
AU7866400A (en) * 1999-10-07 2001-05-10 Baylor College Of Medicine Novel zinc finger protein
WO2002087507A2 (en) * 2001-04-27 2002-11-07 Sunnybrook & Women's College Health Sciences Centre Breast cancer-associated genes and uses thereof
KR100468466B1 (ko) * 2001-08-25 2005-01-27 주식회사 랩 지노믹스 유방암 및 난소암 진단에 유용한 ｂｒｃａ１, ｂｒｃａ２유전자 돌연변이 및 이를 이용한 검색 방법
CN111253483B (zh) * 2020-03-02 2021-07-30 江苏莱森生物科技研究院有限公司 一种抗brca1单克隆抗体及其用途
WO2025059215A1 (en) 2023-09-12 2025-03-20 Aadigen, Llc Methods and compositions for treating or preventing cancer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019369A1 (en) * 1994-01-14 1995-07-20 Vanderbilt University Method for detection and treatment of breast cancer
US5654155A (en) * 1996-02-12 1997-08-05 Oncormed, Inc. Consensus sequence of the human BRCA1 gene
US5756294A (en) * 1995-09-25 1998-05-26 Oncormed, Inc. Susceptibility mutation for breast and ovarian cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019369A1 (en) * 1994-01-14 1995-07-20 Vanderbilt University Method for detection and treatment of breast cancer
US5756294A (en) * 1995-09-25 1998-05-26 Oncormed, Inc. Susceptibility mutation for breast and ovarian cancer
US5654155A (en) * 1996-02-12 1997-08-05 Oncormed, Inc. Consensus sequence of the human BRCA1 gene

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRODY L C ET AL: "Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17;MTO120 Homo sapiens genomic clone MTO120", EMBL NUCLEOTIDE SEQUENCE, XX, XX, 31 December 1994 (1994-12-31), XP002134210 *
BROWN M A ET AL: "PHYSICAL MAPPING, CLONING, AND IDENTIFICATION OF GENES WITHIN A 500-KB REGION CONTAINING BRCA1", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 92, 1 May 1995 (1995-05-01), pages 4362 - 4366, XP002017873, ISSN: 0027-8424 *
HAKEM RAZQALLAH ET AL: "The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.", CELL, vol. 85, no. 7, 1996, pages 1009 - 1023, XP002174576, ISSN: 0092-8674 *
See also references of WO9801460A1 *
SZABO CSILLA I ET AL: "Human, canine and murine BRCA1 genes: Sequence comparison among species.", HUMAN MOLECULAR GENETICS, vol. 5, no. 9, 1996, pages 1289 - 1298, XP002174577, ISSN: 0964-6906 *

Also Published As

Publication number Publication date
CA2259154A1 (en) 1998-01-15
WO1998001460A8 (en) 2000-01-06
AU3655097A (en) 1998-02-02
AU736210B2 (en) 2001-07-26
WO1998001460A1 (en) 1998-01-15
JP2002513272A (ja) 2002-05-08
NZ333635A (en) 2000-06-23
KR20000023600A (ko) 2000-04-25
EP0918788A1 (de) 1999-06-02

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