EP0997715A2 - Spektrophotometrische Vorrichtung zum Verringern des Flüssigkeitsübertrags - Google Patents

Spektrophotometrische Vorrichtung zum Verringern des Flüssigkeitsübertrags Download PDF

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Publication number
EP0997715A2
EP0997715A2 EP99120062A EP99120062A EP0997715A2 EP 0997715 A2 EP0997715 A2 EP 0997715A2 EP 99120062 A EP99120062 A EP 99120062A EP 99120062 A EP99120062 A EP 99120062A EP 0997715 A2 EP0997715 A2 EP 0997715A2
Authority
EP
European Patent Office
Prior art keywords
reagent strip
reagent
strip
support
area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP99120062A
Other languages
English (en)
French (fr)
Other versions
EP0997715B1 (de
EP0997715A3 (de
Inventor
Marilyn Radtke
Gary E. Rehm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of EP0997715A2 publication Critical patent/EP0997715A2/de
Publication of EP0997715A3 publication Critical patent/EP0997715A3/de
Application granted granted Critical
Publication of EP0997715B1 publication Critical patent/EP0997715B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band

Definitions

  • the support table 1 has a plurality of upwardly extending ribs 5 designed to support the reagent strips so that they are held above the upper surfaces of the support table 1.
  • the support table 1 has a first raised platform 6, having the approximate shape of a reagent strip, on which a reagent strip is positioned when being read by a first readhead (not shown), and a second raised platform 7 on which a reagent strip is positioned when being read by a second readhead (not shown).
  • reagent strips used in the spectrophotometer having the support table 1 shown in Fig. 1A have multiple reagent pads which are provided with reagents to test for various conditions.
  • One such reagent pad is designed to detect "occult blood" in urine.
  • Such a reagent pad is impregnated with a conventional reagent which causes a blue color to be formed in the presence of very small concentrations of blood in urine.
  • the apparatus may include a reagent strip pusher arm which is adapted to push the reagent strip along the reagent strip support while the reagent strip is being supported by the reagent strip support, the reagent strip pusher arm being shaped so that no portion of the reagent strip pusher arm makes contact with the reagent pad area of the reagent strip.
  • the spectrophotometer 10 includes a pivot arm 34 having a central portion which is connected to a rotatable shaft 36, which is controllably driven by a motor (not shown).
  • the end of the pivot arm 34 is slidably disposed in a vertical shaft formed in the back of a transfer arm support member 38 to which the transfer arm 18 (Fig. 1) is connected.
  • the transfer arm support member 38 which has a receptacle 40 in which an end of the transfer arm 18 is disposed, is slidably supported by a horizontally disposed cylindrical rod 42.
  • the horizontal position and movement of the transfer arm 18 are controlled by selectively causing the pivot arm 34 to rotate about the central shaft 36 to change the lateral position of the end of the pivot arm 34, and thus the lateral position of the transfer arm support member 38.
  • the movement of the support table 102 causes the advancing tray 80 to move in a circular path, which in turn moves the pegs 86, 88 to cause the reagent strips 14 disposed between them to be periodically moved or indexed rightward through the spectrophotometer 10, so that a reagent strip 14 is disposed at a first reagent strip inspection position beneath the readhead 60, and then is disposed at a second reagent strip inspection position beneath the readhead 62.
  • the pegs 86, 88 move from left to right while they extend upwardly through the reagent strip support table 22, thus moving each of the reagent strips 14 one reagent strip position to the right.
  • the pegs 86, 88 are downwardly retracted so that their upper ends are disposed beneath the upper surface of the support table 22, so that they can be moved from right to left without moving the reagent strips 14.
  • the particular design of the system for conveying the reagent strips 14 from the receiving area 12 to the inspection area within the housing portion 16 and for conveying the reagent strips 14 within the inspection area is not considered necessary to the invention, and other types of conveyor systems could be utilized.
  • Fig. 8 illustrates a plurality of predefined areas of a reagent strip 14.
  • the reagent strip 14 has a reagent pad area 140 which is defined as the area on the reagent strip substrate 24 bounded by the perimeter 142 of an occult blood reagent pad.
  • the reagent pad area 140 has a first area 144 adjacent to it which extends for a predetermined distance, such as about one-fourth or about one-eighth of an inch, from the reagent pad area 140 in a first direction parallel to the longitudinal direction 146 in which the reagent pads 26 of the reagent strip 14 are disposed and a second area 148 adjacent to the reagent pad area 140 which extends for a predetermined distance, such as about one-fourth or about one-eighth of an inch, from the reagent pad area 140 in a second direction parallel to the longitudinal 146 of the reagent strip 14.
  • the combined areas 140, 144, 148 may be referred to as a no-contact area 150.
  • the ribs 128, 130 only extend part way across the reagent strip support 22. That is to further reduce the likelihood of physical contact between the ribs 128, 130 and the reagent pad area 140 and the no-contact area 150. For example, if the occult blood reagent pad is located in the position 26d shown in Fig. 4, there would be no physical contact with the ribs 128, 130 if the reagent strip 14 is properly aligned parallel to its longitudinal axis, as shown in Fig. 4 (because the ribs 128, 130 only contact the area between the adjacent positions 26d and 26e).

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
EP99120062A 1998-10-30 1999-10-19 Spektrophotometrische Vorrichtung zum Verringern des Flüssigkeitsübertrags Expired - Lifetime EP0997715B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US182313 1998-10-30
US09/182,313 US6183694B1 (en) 1998-10-30 1998-10-30 Spectrophotometric apparatus for reducing fluid carryover

Publications (3)

Publication Number Publication Date
EP0997715A2 true EP0997715A2 (de) 2000-05-03
EP0997715A3 EP0997715A3 (de) 2001-11-14
EP0997715B1 EP0997715B1 (de) 2006-08-30

Family

ID=22667916

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99120062A Expired - Lifetime EP0997715B1 (de) 1998-10-30 1999-10-19 Spektrophotometrische Vorrichtung zum Verringern des Flüssigkeitsübertrags

Country Status (8)

Country Link
US (1) US6183694B1 (de)
EP (1) EP0997715B1 (de)
JP (1) JP3462811B2 (de)
AT (1) ATE338275T1 (de)
AU (1) AU768170B2 (de)
CA (1) CA2281168A1 (de)
DE (1) DE69932990T2 (de)
ES (1) ES2272030T3 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183694B1 (en) * 1998-10-30 2001-02-06 Bayer Corporation Spectrophotometric apparatus for reducing fluid carryover
EP1757945A4 (de) * 2004-05-10 2012-01-11 Arkray Inc Analysevorrichtung
EP2795294A4 (de) * 2011-12-16 2015-12-09 Siemens Healthcare Diagnostics System und verfahren zur reagenzkartenausrichtung

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100522722B1 (ko) * 2002-06-14 2005-10-20 강구태 뇨분석기
US7197169B2 (en) * 2003-01-02 2007-03-27 Kuo-Jeng Wang Method for detecting a response of each probe zone on a test strip
KR101257299B1 (ko) 2009-09-09 2013-04-22 한국전자통신연구원 휴대형 배뇨 분석용 디지털 리더기
CN103994974B (zh) * 2014-06-11 2017-02-22 长春理工大学 干式生化分析仪
JP6549962B2 (ja) * 2015-10-09 2019-07-24 栄研化学株式会社 試験片載置体、搬送ユニットおよび試験片分析装置
CN113701883B (zh) * 2021-09-02 2023-09-22 北京环境特性研究所 变距离空间目标光谱特性模拟测量系统及方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055261A (en) 1984-09-11 1991-10-08 Miles Inc. Reagent test strip reading instrument
US4689202A (en) 1984-09-11 1987-08-25 Miles Laboratories, Inc. Reagent test strip reading instrument
DE3940152A1 (de) * 1989-12-05 1991-06-06 Boehringer Mannheim Gmbh Teststreifenauswertegeraet fuer mehrfachteststreifen
DE4425439A1 (de) * 1994-07-19 1996-01-25 Boehringer Mannheim Gmbh Teststreifenauswertegerät mit einer Transporteinheit für Teststreifen
US5654803A (en) * 1996-05-09 1997-08-05 Bayer Corporation Apparatus and method for determination of non-hemolyzed levels of occult blood in urine
US6261522B1 (en) * 1998-10-13 2001-07-17 Bayer Corporation Spectrophotometric apparatus with reagent strip detection
US6183694B1 (en) * 1998-10-30 2001-02-06 Bayer Corporation Spectrophotometric apparatus for reducing fluid carryover

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183694B1 (en) * 1998-10-30 2001-02-06 Bayer Corporation Spectrophotometric apparatus for reducing fluid carryover
EP1757945A4 (de) * 2004-05-10 2012-01-11 Arkray Inc Analysevorrichtung
US8298484B2 (en) 2004-05-10 2012-10-30 Arkray, Inc. Analyzing apparatus
EP2795294A4 (de) * 2011-12-16 2015-12-09 Siemens Healthcare Diagnostics System und verfahren zur reagenzkartenausrichtung
US10302572B2 (en) 2011-12-16 2019-05-28 Siemens Healthcare Diagnostics Inc. Reagent card alignment system
US10900910B2 (en) 2011-12-16 2021-01-26 Siemens Healthcare Diagnostics Inc. Reagent card alignment method for sample dispensing

Also Published As

Publication number Publication date
AU768170B2 (en) 2003-12-04
EP0997715B1 (de) 2006-08-30
AU5709899A (en) 2000-05-04
ATE338275T1 (de) 2006-09-15
JP3462811B2 (ja) 2003-11-05
DE69932990T2 (de) 2007-04-05
CA2281168A1 (en) 2000-04-30
JP2000137028A (ja) 2000-05-16
DE69932990D1 (de) 2006-10-12
EP0997715A3 (de) 2001-11-14
US6183694B1 (en) 2001-02-06
ES2272030T3 (es) 2007-04-16

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