EP1005338A4 - Derives d'aurone substitues - Google Patents

Derives d'aurone substitues

Info

Publication number: EP1005338A4
Authority: EP; European Patent Office
Prior art keywords: substituted aurone; aurone derivatives; derivatives; substituted; aurone
Prior art date: 1997-07-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP98937084A

Other languages

German (de)

English (en)

Other versions

EP1005338A1 (fr

Inventor

Wai-Lam Alex Chu

Flemming R Jensen

Thomas B Jensen

Birgitte Soekilde

Alexandra Santana-Soerenson

James B Mcalpine

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Phytera Inc

Original Assignee

Phytera Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-24

Publication date

2001-11-07

1998-07-24 Application filed by Phytera Inc filed Critical Phytera Inc

2000-06-07 Publication of EP1005338A1 publication Critical patent/EP1005338A1/fr

2001-11-07 Publication of EP1005338A4 publication Critical patent/EP1005338A4/fr

Status Withdrawn legal-status Critical Current

Links

150000001529 aurone derivatives Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EP98937084A 1997-07-25 1998-07-24 Derives d'aurone substitues Withdrawn EP1005338A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5374297P	1997-07-25	1997-07-25
US53742P		1997-07-25
PCT/US1998/015388 WO1999004789A1 (fr)	1997-07-25	1998-07-24	Derives d'aurone substitues

Publications (2)

Publication Number	Publication Date
EP1005338A1 EP1005338A1 (fr)	2000-06-07
EP1005338A4 true EP1005338A4 (fr)	2001-11-07

Family

ID=21986251

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP98937084A Withdrawn EP1005338A4 (fr)	1997-07-25	1998-07-24	Derives d'aurone substitues

Country Status (6)

Country	Link
EP (1)	EP1005338A4 (fr)
JP (1)	JP2001510801A (fr)
AU (1)	AU751213B2 (fr)
BR (1)	BR9811554A (fr)
CA (1)	CA2297753A1 (fr)
WO (1)	WO1999004789A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60232289D1 (de)	2001-04-06	2009-06-25	Merck Patent Gmbh	Photopolymerisierbare Verbindungen
EP1247796B1 (fr) *	2001-04-06	2009-05-13	MERCK PATENT GmbH	Composés photopolymérisables
GB2386891A (en) *	2002-03-28	2003-10-01	Pantherix Ltd	Antibacterial benzofuran-2H-3-ones
CN104529961B (zh) *	2014-12-29	2016-07-06	贺州学院	荸荠皮提取5-异戊烯基金鱼草素的方法
CN105646417B (zh) *	2016-03-31	2017-12-05	四川大学	一类4‑羟基噢哢类化合物、其制备方法和用途
WO2017180644A1 (fr)	2016-04-11	2017-10-19	Middle Tennessee State University	Aurones thérapeutiques
CN106632181B (zh) *	2016-09-30	2019-03-19	四川大学	噢哢曼尼希碱类化合物、其制备方法和用途
CN106632191B (zh) *	2016-09-30	2018-10-30	四川大学	高异黄酮曼尼希碱类化合物、其制备方法和用途
CN109824637B (zh) *	2019-03-13	2021-03-30	南阳师范学院	一种茚酮查尔酮氨基甲酸酯类化合物及其制备方法和用途
CN118307504A (zh) *	2023-01-06	2024-07-09	中国科学院上海药物研究所	橙酮衍生物或类似物、其制备方法、药物组合物和用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1250340A (fr) *	1967-11-14	1971-10-20
US3721668A (en) *	1969-07-10	1973-03-20	Schering Ag	Novel 5-nitro-imidazole antimicrobially effective compounds
US3975380A (en) *	1974-06-03	1976-08-17	Smithkline Corporation	Substituted aurones
WO1997026873A1 (fr) *	1996-01-26	1997-07-31	Phytera, Inc.	Derives d'aurone antimicrobiens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4067993A (en) *	1975-09-24	1978-01-10	Riker Laboratories, Inc.	Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids
IL58229A (en) *	1978-09-13	1984-05-31	Lilly Industries Ltd	Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them
US4806660A (en) *	1987-11-06	1989-02-21	Pennwalt Corporation	Aurone oxypropanolamines

1998
- 1998-07-24 AU AU85876/98A patent/AU751213B2/en not_active Ceased
- 1998-07-24 BR BR9811554-5A patent/BR9811554A/pt not_active Application Discontinuation
- 1998-07-24 WO PCT/US1998/015388 patent/WO1999004789A1/fr not_active Ceased
- 1998-07-24 CA CA002297753A patent/CA2297753A1/fr not_active Abandoned
- 1998-07-24 JP JP2000503845A patent/JP2001510801A/ja active Pending
- 1998-07-24 EP EP98937084A patent/EP1005338A4/fr not_active Withdrawn

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1250340A (fr) *	1967-11-14	1971-10-20
US3716531A (en) *	1967-11-14	1973-02-13	Schering Ag	5-nitro-furfurylidene antimicrobic agents
US3721668A (en) *	1969-07-10	1973-03-20	Schering Ag	Novel 5-nitro-imidazole antimicrobially effective compounds
US3975380A (en) *	1974-06-03	1976-08-17	Smithkline Corporation	Substituted aurones
WO1997026873A1 (fr) *	1996-01-26	1997-07-31	Phytera, Inc.	Derives d'aurone antimicrobiens

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALBRECHT, R. ET AL: "Chemotherapeutic nitroheterocycles. V. Nitrofurfurylidene-, nitrothenylidene-, and nitropyrrolylmethylene-derivatives of 3-benzofuranones, chromanones and some S- and N-analogs and their antimicrobial activity", CHIM. THER. (1971), 6(5), 352-7, 1971, XP001024244 *
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TOYOSHIMA, SHOJI ET AL: "Nitrofurfurylidene benzofuranones", XP002177245, retrieved from STN Database accession no. 71:13010 CA *
ISMAIL, E. ET AL: "Antibacterial and anthelminthic properties of visnaginone and khellinone derivatives", ARZNEIM.-FORSCH. (1977), 27(7), 1393-4, 1977, XP001024177 *
See also references of WO9904789A1 *
TOMOZANE, HIDEO ET AL: "Syntheses and antifungal activities of dl-griseofulvin and its congeners. I", CHEM. PHARM. BULL. (1990), 38(4), 925-9, 1990, XP001024178 *

Also Published As

Publication number	Publication date
JP2001510801A (ja)	2001-08-07
AU8587698A (en)	1999-02-16
EP1005338A1 (fr)	2000-06-07
CA2297753A1 (fr)	1999-02-04
BR9811554A (pt)	2000-09-12
WO1999004789A1 (fr)	1999-02-04
AU751213B2 (en)	2002-08-08

Legal Events

Date	Code	Title	Description
2000-04-20	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-06-07	17P	Request for examination filed	Effective date: 20000217
2000-06-07	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): DE DK ES FR GB IT NL SE
2000-11-15	RIN1	Information on inventor provided before grant (corrected)	Inventor name: MCALPINE, JAMES, B. Inventor name: SANTANA-SOERENSON, ALEXANDRA Inventor name: SOEKILDE, BIRGITTE Inventor name: JENSEN, THOMAS, B. Inventor name: JENSEN, FLEMMING, R. Inventor name: CHU, WAI-LAM, ALEX
2001-11-07	A4	Supplementary search report drawn up and despatched	Effective date: 20010926
2001-11-07	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): DE DK ES FR GB IT NL SE
2001-11-07	RIC1	Information provided on ipc code assigned before grant	Free format text: 7C 07D 307/78 A, 7C 07D 307/83 B, 7C 07D 307/82 B, 7A 61K 31/34 B
2001-12-05	RIN1	Information on inventor provided before grant (corrected)	Inventor name: NOBLE, CATHERINE Inventor name: STAFFORD, ANGELA M. Inventor name: MCALPINE, JAMES, B. Inventor name: SANTANA-SOERENSON, ALEXANDRA Inventor name: SOEKILDE, BIRGITTE Inventor name: JENSEN, THOMAS, B. Inventor name: JENSEN, FLEMMING, R. Inventor name: CHU, WAI-LAM, ALEX
2003-07-04	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2003-08-20	18D	Application deemed to be withdrawn	Effective date: 20030201

Publication	Publication Date	Title
PL334847A1 (en)	2000-03-27	Substituted 3-heterocyclyl-benzoyl derivatives
EG24081A (en)	2008-05-11	4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives
GB9702194D0 (en)	1997-03-26	Sulphonide derivatives
HUP0003642A3 (en)	2001-11-28	N-alkanoylphenylalanine derivatives
ZA987602B (en)	1999-05-04	N-alkanoylphenylalanine derivatives
PL335999A1 (en)	2000-06-05	Substituted 3-cyanoquinolines
AP2000001795A0 (en)	2000-06-30	Substituted 4-aminothiazol-2-yol
GB9809664D0 (en)	1998-07-01	a-Ketoamide derivatives
HUP9801168A3 (en)	1999-11-29	Triazinylaminostilbene derivatives
EG23802A (en)	2007-08-22	2-Phenylpyran-4-one derivatives
GB2321457B (en)	2001-02-28	5-Aroylnaphthalene derivatives
IL132982A0 (en)	2001-03-19	Cis-disubstituted aminocycloalkyl-pyrrolidine derivatives
PL340541A1 (en)	2001-02-12	Pyridipyrrole derivative
GB9815505D0 (en)	1998-09-16	Polypeptide derivatives
GB9715821D0 (en)	1997-10-01	Amidino-camptothecin derivatives
GB9725541D0 (en)	1998-02-04	Amino-benzothiazole derivatives
ZA98611B (en)	1998-08-17	Imino-aza-anthracyclinone derivatives
PL334546A1 (en)	2000-03-13	Substituted 4-benzoylpyrazoles
IL130971A0 (en)	2001-01-28	Gemcitabine derivatives
ZA983116B (en)	1998-10-21	Arylsecocholadiene derivatives
EP1061912A4 (fr)	2003-01-02	Derives de phenanthrofuran
HU9800889D0 (en)	1998-06-29	New naphtylpiperazine derivatives
IL131159A0 (en)	2001-01-28	4-Aminoethoxyindazole derivatives
ZA985761B (en)	1999-01-27	Substituted aryluracils
IL133261A0 (en)	2001-04-30	Substituted naphthropyrans