EP1012155A4 - Proteine 3 de decouplage d'origine humaine - Google Patents

Proteine 3 de decouplage d'origine humaine

Info

Publication number
EP1012155A4
EP1012155A4 EP19980923517 EP98923517A EP1012155A4 EP 1012155 A4 EP1012155 A4 EP 1012155A4 EP 19980923517 EP19980923517 EP 19980923517 EP 98923517 A EP98923517 A EP 98923517A EP 1012155 A4 EP1012155 A4 EP 1012155A4
Authority
EP
European Patent Office
Prior art keywords
human origin
decoupling protein
decoupling
protein
origin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980923517
Other languages
German (de)
English (en)
Other versions
EP1012155A1 (fr
Inventor
Qingyun Liu
Fang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9716886.8A external-priority patent/GB9716886D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1012155A1 publication Critical patent/EP1012155A1/fr
Publication of EP1012155A4 publication Critical patent/EP1012155A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP19980923517 1997-05-20 1998-05-19 Proteine 3 de decouplage d'origine humaine Withdrawn EP1012155A4 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US4717997P 1997-05-20 1997-05-20
US47179P 1997-05-20
GB9716886 1997-08-08
GBGB9716886.8A GB9716886D0 (en) 1997-08-08 1997-08-08 Human uncoupling protein 3
US6914197P 1997-12-09 1997-12-09
US69141P 1997-12-09
PCT/US1998/010215 WO1998052958A1 (fr) 1997-05-20 1998-05-19 Proteine 3 de decouplage d'origine humaine

Publications (2)

Publication Number Publication Date
EP1012155A1 EP1012155A1 (fr) 2000-06-28
EP1012155A4 true EP1012155A4 (fr) 2002-11-04

Family

ID=27268968

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980923517 Withdrawn EP1012155A4 (fr) 1997-05-20 1998-05-19 Proteine 3 de decouplage d'origine humaine

Country Status (4)

Country Link
EP (1) EP1012155A4 (fr)
JP (1) JP2002502240A (fr)
CA (1) CA2289945A1 (fr)
WO (1) WO1998052958A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001526538A (ja) 1997-05-07 2001-12-18 ノバルティス アクチエンゲゼルシャフト 脱共役タンパク質相同物：ｕｃｐ３
AU6041399A (en) 1998-09-22 2000-04-10 Genentech Inc. Ucp4
US7342102B2 (en) 1998-11-30 2008-03-11 Genentech, Inc. Uncoupling protein 5 (UCP5)
ATE492640T1 (de) 1998-11-30 2011-01-15 Genentech Inc Loslösendes protein 5 - ucp5

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039432A1 (fr) * 1997-03-05 1998-09-11 Smithkline Beecham Plc Polynucleotides et polypeptides appartenant a la famille des proteines non liantes
WO1998050542A1 (fr) * 1997-05-07 1998-11-12 Novartis Ag Homologue de proteine de decouplage: ucp3

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039432A1 (fr) * 1997-03-05 1998-09-11 Smithkline Beecham Plc Polynucleotides et polypeptides appartenant a la famille des proteines non liantes
WO1998050542A1 (fr) * 1997-05-07 1998-11-12 Novartis Ag Homologue de proteine de decouplage: ucp3

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BOSS O ET AL: "UNCOUPLING PROTEIN-3: A NEW MEMBER OF THE MITOCHONDRIAL CARRIER FAMILY WITH TISSUE-SPECIFIC EXPRESSION", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 408, no. 1, 1997, pages 39 - 42, XP002067895, ISSN: 0014-5793 *
DATABASE SWALLPROT [online] XP002214359, Database accession no. p55916 *
DATABASE SWALLPROT [online] XP002214361, Database accession no. p56501 *
MATSUDA J ET AL: "Cloning of rat uncoupling protein-3 and uncoupling protein-2 cDNAs: their gene expression in rats fed high-fat diet", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 418, no. 1-2, 24 November 1997 (1997-11-24), pages 200 - 204, XP004261541, ISSN: 0014-5793 *
See also references of WO9852958A1 *
YOSHITOMI H ET AL: "Cloning of mouse uncoupling protein 3 cDNA and 5'-flanking region, and its genetic map", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 215, no. 1, July 1998 (1998-07-01), pages 77 - 84, XP004149231, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
WO1998052958A1 (fr) 1998-11-26
JP2002502240A (ja) 2002-01-22
CA2289945A1 (fr) 1998-11-26
EP1012155A1 (fr) 2000-06-28

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