EP1012233A4 - Transgen produziertes prolactin - Google Patents

Transgen produziertes prolactin

Info

Publication number
EP1012233A4
EP1012233A4 EP97931220A EP97931220A EP1012233A4 EP 1012233 A4 EP1012233 A4 EP 1012233A4 EP 97931220 A EP97931220 A EP 97931220A EP 97931220 A EP97931220 A EP 97931220A EP 1012233 A4 EP1012233 A4 EP 1012233A4
Authority
EP
European Patent Office
Prior art keywords
transgenically
prolactin
produced
prolactin produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97931220A
Other languages
English (en)
French (fr)
Other versions
EP1012233A1 (de
Inventor
Yann Echelard
Brian Wilburn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
rEVO Biologics Inc
Original Assignee
GTC Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GTC Biotherapeutics Inc filed Critical GTC Biotherapeutics Inc
Publication of EP1012233A1 publication Critical patent/EP1012233A1/de
Publication of EP1012233A4 publication Critical patent/EP1012233A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2257—Prolactin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57554—Prolactin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/102—Caprine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP97931220A 1997-06-17 1997-06-17 Transgen produziertes prolactin Withdrawn EP1012233A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1997/010489 WO1998058051A1 (en) 1997-06-17 1997-06-17 Transgenically produced prolactin

Publications (2)

Publication Number Publication Date
EP1012233A1 EP1012233A1 (de) 2000-06-28
EP1012233A4 true EP1012233A4 (de) 2004-05-06

Family

ID=22261099

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97931220A Withdrawn EP1012233A4 (de) 1997-06-17 1997-06-17 Transgen produziertes prolactin

Country Status (3)

Country Link
EP (1) EP1012233A4 (de)
AU (1) AU3491197A (de)
WO (1) WO1998058051A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL153507A0 (en) * 2000-06-19 2003-07-06 Genzyme Transgenics Corp Transgenically produced platelet derived growth factor
NZ515178A (en) * 2001-11-23 2004-09-24 Agres Ltd Modulating prolactin receptors to affect a physiological response

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189426A (en) * 1976-04-12 1980-02-19 Hoffmann-La Roche, Inc. Recombinant hormonal compositions and method
IL91928A (en) * 1989-10-08 1994-07-31 Amrad Res & Dev Pharmaceutical compositions containing prolactin

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
EBERT K M ET AL: "TRANSGENIC PRODUCTION OF A VARIANT OF HUMAN TISSUE-TYPE PLASMINOGEN ACTIVATOR IN GOAT MILK: GENERATION OF TRANSGENIC GOATS AND ANALYSIS OF EXPRESSION", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 9, no. 9, 1 September 1991 (1991-09-01), pages 835 - 838, XP000574075, ISSN: 0733-222X *
GAVIN W G ET AL: "EXPRESSION OF THE ANTIBODY HBR96-2 IN THE MILK OF TRANSGENIC MICE AND PRODUCTION OF HBR96-2 TRANSGENIC GOATS", THERIOGENOLOGY, LOS ALTOS, CA, US, vol. 47, no. 1, January 1997 (1997-01-01), pages 214, XP000892952, ISSN: 0093-691X *
See also references of WO9858051A1 *
WILBURN B ET AL: "High-level expression of recombinant human prolactin in the milk of transgenic mice", THERIOGENOLOGY, vol. 47, no. 1, January 1997 (1997-01-01), Annual Conference of the International Embryo Transfer Society;Nice, France; January 12-14, 1997, pages 219, XP002272711, ISSN: 0093-691X *

Also Published As

Publication number Publication date
EP1012233A1 (de) 2000-06-28
AU3491197A (en) 1999-01-04
WO1998058051A1 (en) 1998-12-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000106

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE FR GB LI NL SE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GTC BIOTHERAPEUTICS, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20040318

17Q First examination report despatched

Effective date: 20041021

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080103