EP1023295A4 - Prodrogen von fibrinogenrezeptor-antagonisten - Google Patents
Prodrogen von fibrinogenrezeptor-antagonistenInfo
- Publication number
- EP1023295A4 EP1023295A4 EP98906092A EP98906092A EP1023295A4 EP 1023295 A4 EP1023295 A4 EP 1023295A4 EP 98906092 A EP98906092 A EP 98906092A EP 98906092 A EP98906092 A EP 98906092A EP 1023295 A4 EP1023295 A4 EP 1023295A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fibrinogenic
- predictions
- receptor antagonist
- antagonist
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3690197P | 1997-02-06 | 1997-02-06 | |
| US36901P | 1997-02-06 | ||
| GBGB9707489.2A GB9707489D0 (en) | 1997-04-14 | 1997-04-14 | Fibrinogen receptor antagonist prodrugs |
| GB9707489 | 1997-04-14 | ||
| PCT/US1998/001998 WO1998034935A1 (en) | 1997-02-06 | 1998-02-02 | Fibrinogen receptor antagonist prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1023295A1 EP1023295A1 (de) | 2000-08-02 |
| EP1023295A4 true EP1023295A4 (de) | 2001-01-24 |
Family
ID=26311371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP98906092A Withdrawn EP1023295A4 (de) | 1997-02-06 | 1998-02-02 | Prodrogen von fibrinogenrezeptor-antagonisten |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1023295A4 (de) |
| JP (1) | JP2001512439A (de) |
| AU (1) | AU747293B2 (de) |
| CA (1) | CA2279927A1 (de) |
| WO (1) | WO1998034935A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK171698A3 (en) | 1996-06-14 | 1999-10-08 | Biocryst Pharm Inc | Substituted cyclopentane compounds useful as neuraminidase inhibitors |
| HUP0100142A3 (en) | 1997-12-17 | 2002-01-28 | Biocryst Pharmaceuticals Inc B | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| US6025358A (en) * | 1998-06-11 | 2000-02-15 | G. D. Searle & Co. | Double prodrugs of potent GP IIb/IIIa antagonists |
| AU1520300A (en) | 1998-11-05 | 2000-05-29 | Biocryst Pharmaceuticals, Inc. | New cyclopentane and cyclopentene compounds and use for detecting influenza virus |
| EP1187825A1 (de) * | 1999-06-07 | 2002-03-20 | Shire Biochem Inc. | Thiophen integrin inhibitoren |
| CN102015675B (zh) * | 2008-02-21 | 2014-07-02 | 赛诺菲 | 作为凝血因子Xa和凝血酶的抑制剂的氯噻吩-酰胺 |
| CN111943818B (zh) * | 2020-09-16 | 2023-01-24 | 天津均凯农业科技有限公司 | 一种制备4,4′-双三氟甲基二苯醚的方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008577A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994008962A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994012181A1 (en) * | 1992-12-01 | 1994-06-09 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994018981A1 (en) * | 1993-02-22 | 1994-09-01 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| EP0656348A2 (de) * | 1993-12-03 | 1995-06-07 | F. Hoffmann-La Roche Ag | Essigsäurederivate als Arzneimittel |
-
1998
- 1998-02-02 JP JP53482498A patent/JP2001512439A/ja active Pending
- 1998-02-02 EP EP98906092A patent/EP1023295A4/de not_active Withdrawn
- 1998-02-02 AU AU61413/98A patent/AU747293B2/en not_active Ceased
- 1998-02-02 CA CA002279927A patent/CA2279927A1/en not_active Abandoned
- 1998-02-02 WO PCT/US1998/001998 patent/WO1998034935A1/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008577A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994008962A1 (en) * | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994012181A1 (en) * | 1992-12-01 | 1994-06-09 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994018981A1 (en) * | 1993-02-22 | 1994-09-01 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| EP0656348A2 (de) * | 1993-12-03 | 1995-06-07 | F. Hoffmann-La Roche Ag | Essigsäurederivate als Arzneimittel |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO9834935A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998034935A1 (en) | 1998-08-13 |
| CA2279927A1 (en) | 1998-08-13 |
| AU6141398A (en) | 1998-08-26 |
| EP1023295A1 (de) | 2000-08-02 |
| JP2001512439A (ja) | 2001-08-21 |
| AU747293B2 (en) | 2002-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19990906 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20001212 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
| RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 07D 487/00 A, 7C 07D 491/00 B, 7C 07D 495/00 B, 7C 07C 69/02 B, 7C 07D 487/04 B, 7C 07D 209/42 B, 7C 07D 333/38 B, 7C 07C 311/19 B, 7A 61K 31/55 B |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20020301 |