EP1027352A4 - CARBAPENEMIC CLASS ANTIBACTERIAL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT - Google Patents

CARBAPENEMIC CLASS ANTIBACTERIAL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT

Info

Publication number
EP1027352A4
EP1027352A4 EP98953736A EP98953736A EP1027352A4 EP 1027352 A4 EP1027352 A4 EP 1027352A4 EP 98953736 A EP98953736 A EP 98953736A EP 98953736 A EP98953736 A EP 98953736A EP 1027352 A4 EP1027352 A4 EP 1027352A4
Authority
EP
European Patent Office
Prior art keywords
carbapenemic
compositions
treatment
methods
antibacterial compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98953736A
Other languages
German (de)
French (fr)
Other versions
EP1027352A1 (en
Inventor
Lovji D Cama
Ronald W Ratcliffe
Robert R Wilkening
Kenneth J Wildonger
Wanying Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9806431.4A external-priority patent/GB9806431D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1027352A1 publication Critical patent/EP1027352A1/en
Publication of EP1027352A4 publication Critical patent/EP1027352A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP98953736A 1997-10-23 1998-10-19 CARBAPENEMIC CLASS ANTIBACTERIAL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT Withdrawn EP1027352A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6303197P 1997-10-23 1997-10-23
US63031P 1997-10-23
GBGB9806431.4A GB9806431D0 (en) 1998-03-25 1998-03-25 Carbapenem antibacterial compounds,compositions containing such compounds and methods of treatment
GB9806431 1998-03-25
PCT/US1998/022110 WO1999020627A1 (en) 1997-10-23 1998-10-19 Carbapenem antibacterial compounds, compositions and methods of treatment

Publications (2)

Publication Number Publication Date
EP1027352A1 EP1027352A1 (en) 2000-08-16
EP1027352A4 true EP1027352A4 (en) 2001-09-19

Family

ID=26313358

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98953736A Withdrawn EP1027352A4 (en) 1997-10-23 1998-10-19 CARBAPENEMIC CLASS ANTIBACTERIAL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT

Country Status (5)

Country Link
EP (1) EP1027352A4 (en)
JP (1) JP2002509856A (en)
AU (1) AU739799B2 (en)
CA (1) CA2306565A1 (en)
WO (1) WO1999020627A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2449060A1 (en) * 2001-06-01 2002-12-12 Nikolai Ignatyev Process for the preparation of compounds containing perfluoroalkanesulfonic acid groups
WO2015012515A1 (en) * 2013-07-25 2015-01-29 동아에스티 주식회사 Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016080A1 (en) * 1992-02-06 1993-08-19 Yamanouchi Pharmaceutical Co., Ltd. Novel carbapenem derivative
US5451579A (en) * 1994-02-15 1995-09-19 Merck & Co., Inc. 1-β-methyl-carbapenem, compositions containing same and methods of use
WO1997040048A1 (en) * 1996-04-24 1997-10-30 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
WO1998010761A1 (en) * 1996-09-13 1998-03-19 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756725A (en) * 1996-04-24 1998-05-26 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016080A1 (en) * 1992-02-06 1993-08-19 Yamanouchi Pharmaceutical Co., Ltd. Novel carbapenem derivative
US5451579A (en) * 1994-02-15 1995-09-19 Merck & Co., Inc. 1-β-methyl-carbapenem, compositions containing same and methods of use
WO1997040048A1 (en) * 1996-04-24 1997-10-30 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
WO1998010761A1 (en) * 1996-09-13 1998-03-19 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9920627A1 *

Also Published As

Publication number Publication date
AU739799B2 (en) 2001-10-18
EP1027352A1 (en) 2000-08-16
AU1103099A (en) 1999-05-10
WO1999020627A1 (en) 1999-04-29
JP2002509856A (en) 2002-04-02
CA2306565A1 (en) 1999-04-29

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