EP1046036A4 - Procedes d'obtention de sondes de fonction de peptides - Google Patents

Procedes d'obtention de sondes de fonction de peptides

Info

Publication number
EP1046036A4
EP1046036A4 EP98939132A EP98939132A EP1046036A4 EP 1046036 A4 EP1046036 A4 EP 1046036A4 EP 98939132 A EP98939132 A EP 98939132A EP 98939132 A EP98939132 A EP 98939132A EP 1046036 A4 EP1046036 A4 EP 1046036A4
Authority
EP
European Patent Office
Prior art keywords
methods
peptide function
obtaining probes
probes
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP98939132A
Other languages
German (de)
English (en)
Other versions
EP1046036A1 (fr
Inventor
James S Huston
T William Hutchens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1046036A1 publication Critical patent/EP1046036A1/fr
Publication of EP1046036A4 publication Critical patent/EP1046036A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
EP98939132A 1997-07-29 1998-07-29 Procedes d'obtention de sondes de fonction de peptides Ceased EP1046036A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90303597A 1997-07-29 1997-07-29
US903035 1997-07-29
PCT/US1998/015895 WO1999006833A1 (fr) 1997-07-29 1998-07-29 Procedes d'obtention de sondes de fonction de peptides

Publications (2)

Publication Number Publication Date
EP1046036A1 EP1046036A1 (fr) 2000-10-25
EP1046036A4 true EP1046036A4 (fr) 2003-08-27

Family

ID=25416830

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98939132A Ceased EP1046036A4 (fr) 1997-07-29 1998-07-29 Procedes d'obtention de sondes de fonction de peptides

Country Status (3)

Country Link
EP (1) EP1046036A4 (fr)
CA (1) CA2338865A1 (fr)
WO (1) WO1999006833A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037517A1 (en) 1993-05-28 2002-03-28 Hutchens T. William Methods for sequencing biopolymers
ATE242485T1 (de) 1993-05-28 2003-06-15 Baylor College Medicine Verfahren und massenspektrometer zur desorption und ionisierung von analyten
US7179638B2 (en) 1999-07-30 2007-02-20 Large Scale Biology Corporation Microarrays and their manufacture by slicing
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
WO2001098458A2 (fr) * 2000-06-19 2001-12-27 Zyomyx, Inc. Procédés permettant d'immobiliser des polypeptides
EP1360490B1 (fr) 2001-01-23 2011-12-21 President and Fellows of Harvard College Reseaux de proteines a acide nucleique programmable
FR2821856B1 (fr) * 2001-03-09 2003-12-26 Didier Elmlinger Procede de criblage croise d'une banque d'expression d'adn et d'une banque de molecules cibles isolees sur un support permettant la comparaison simultanee de l'affinite et la selectivite de leurs interactions
EP1580559B1 (fr) 2004-03-23 2013-12-25 Bio-Rad Laboratories, Inc. Procedes visant a reduire la variance de concentration d'analytes des melanges d'echantillons complexes
JP2008538112A (ja) 2005-03-23 2008-10-09 バイオ−ラッド ラボラトリーズ インコーポレーティッド 常磁性特性を持つ小粒子に結合した、多様な化学ライブラリー
US8178316B2 (en) 2006-06-29 2012-05-15 President And Fellows Of Harvard College Evaluating proteins
US12135330B2 (en) 2017-03-31 2024-11-05 Charles River Laboratories International, Inc. Articles and methods involving detection of binding

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006213A1 (fr) * 1991-09-23 1993-04-01 Medical Research Council Production d'anticorps chimeriques - une approche combinatoire
WO1998015833A1 (fr) * 1996-10-08 1998-04-16 Universiteit Utrecht Procedes et systemes permettant de selectionner des peptides et des proteines qui possedent une affinite specifique envers une cible

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
DE614989T1 (de) * 1993-02-17 1995-09-28 Morphosys Proteinoptimierung Verfahren für in vivo Selektion von Ligandenbindende Proteine.
US5464745A (en) * 1993-03-31 1995-11-07 Novagen, Inc. Protein ligand binding region mapping system
US5521077A (en) * 1994-04-28 1996-05-28 The Leland Stanford Junior University Method of generating multiple protein variants and populations of protein variants prepared thereby

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006213A1 (fr) * 1991-09-23 1993-04-01 Medical Research Council Production d'anticorps chimeriques - une approche combinatoire
WO1998015833A1 (fr) * 1996-10-08 1998-04-16 Universiteit Utrecht Procedes et systemes permettant de selectionner des peptides et des proteines qui possedent une affinite specifique envers une cible

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KRUIF DE J ET AL: "SELECTION AND APPLICATION OF HUMAN SINGLE CHAIN FV ANTIBODY FRAGMENTS FROM A SEMI-SYNTHETIC PHAGE ANTOBODY DISPLEY LIBRARY WITHDESIGNED CDR3 REGIONS", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 248, no. 1, 21 April 1995 (1995-04-21), pages 97 - 105, XP000646544, ISSN: 0022-2836 *
See also references of WO9906833A1 *

Also Published As

Publication number Publication date
EP1046036A1 (fr) 2000-10-25
CA2338865A1 (fr) 1999-02-11
WO1999006833A1 (fr) 1999-02-11

Similar Documents

Publication Publication Date Title
GB9707414D0 (en) Anatomical probe
PL326483A1 (en) Method of obtaining dextrane
PL340212A1 (en) Method of obtaining n-butanol
EP1046036A4 (fr) Procedes d'obtention de sondes de fonction de peptides
ZA983065B (en) Inhibitors of protein farnesyltranferase
PL335163A1 (en) Method of obtaining substituted thiazolydinodione
EP1020717A4 (fr) Sonde pitot-statique
GB9715747D0 (en) Method of testing
PL335074A1 (en) Method of obtaining eprosartane
PL335075A1 (en) Method of obtaining eprosartane
PL334901A1 (en) Method of obtaining benzothiazolones
PL339188A1 (en) Method of obtaining oxaphosphorin-2-amines
PL341358A1 (en) Method of obtaining paroxetin chlorhydride
GB2314420B (en) Method of measuring position
PL340915A1 (en) Method of obtaining azacycloalkylalkanoyl pseudotetrapeptides
PL332672A1 (en) Testing probe
HK1034113A (en) Methods for obtaining probes of peptide function
PL341302A1 (en) Method of obtaining chlorobenzoxazoles
PL336266A1 (en) Method of obtaining epsilon-caprolactams
GB2329717B (en) Insulated joint tester
PL340497A1 (en) Method of obtaining formylimidazoles
GB9705023D0 (en) Detection of proteins
TW299834U (en) Improved probe structure
PL318681A1 (en) Method of measuring small inclination angles
GB9626065D0 (en) Measurement of welds

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000523

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB IE IT LI LU NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20030715

RIC1 Information provided on ipc code assigned before grant

Ipc: 7G 01N 33/68 B

Ipc: 7C 07K 1/04 B

Ipc: 7B 01J 19/00 A

17Q First examination report despatched

Effective date: 20040726

17Q First examination report despatched

Effective date: 20040726

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20091106

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1034113

Country of ref document: HK