EP1051507A4 - Antigen-spezifische zellen, verfahren zu deren herstellung und deren verwendungen - Google Patents

Antigen-spezifische zellen, verfahren zu deren herstellung und deren verwendungen

Info

Publication number
EP1051507A4
EP1051507A4 EP99902434A EP99902434A EP1051507A4 EP 1051507 A4 EP1051507 A4 EP 1051507A4 EP 99902434 A EP99902434 A EP 99902434A EP 99902434 A EP99902434 A EP 99902434A EP 1051507 A4 EP1051507 A4 EP 1051507A4
Authority
EP
European Patent Office
Prior art keywords
cells
antigen
generating
methods
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99902434A
Other languages
English (en)
French (fr)
Other versions
EP1051507A1 (de
Inventor
Bruce L Roberts
Charles A Nicolette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of EP1051507A1 publication Critical patent/EP1051507A1/de
Publication of EP1051507A4 publication Critical patent/EP1051507A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99902434A 1998-01-26 1999-01-25 Antigen-spezifische zellen, verfahren zu deren herstellung und deren verwendungen Withdrawn EP1051507A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12205398P 1998-01-26 1998-01-26
US122053P 1998-01-26
US8003698P 1998-03-31 1998-03-31
US80036P 1998-03-31
PCT/US1999/001462 WO1999037797A1 (en) 1998-01-26 1999-01-25 Antigen-specific cells, methods of generating these cells and uses thereof

Publications (2)

Publication Number Publication Date
EP1051507A1 EP1051507A1 (de) 2000-11-15
EP1051507A4 true EP1051507A4 (de) 2003-02-05

Family

ID=26762987

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99902434A Withdrawn EP1051507A4 (de) 1998-01-26 1999-01-25 Antigen-spezifische zellen, verfahren zu deren herstellung und deren verwendungen

Country Status (5)

Country Link
EP (1) EP1051507A4 (de)
JP (1) JP2002500891A (de)
AU (1) AU761256B2 (de)
CA (1) CA2318979A1 (de)
WO (1) WO1999037797A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000067761A1 (en) * 1999-05-06 2000-11-16 Wake Forest University Compositions and methods for identifying antigens which elicit an immune response
CA3009852A1 (en) * 2015-12-28 2017-07-06 Novartis Ag Methods of making chimeric antigen receptor-expressing cells
WO2018064718A1 (en) * 2016-10-04 2018-04-12 The Council Of The Queensland Institute Of Medical Research Peptide libraries and methods of use
JP2022093945A (ja) * 2020-12-14 2022-06-24 株式会社山田養蜂場本社 Ｂ細胞数増加剤

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021126A1 (en) * 1993-03-18 1994-09-29 Ludwig Institute For Cancer Research Nucleic acid coding for a tumor rejection antigen precursor
WO1997026535A1 (en) * 1996-01-17 1997-07-24 Ludwig Institute For Cancer Research Isolated tyrosinase derived peptides and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695937A (en) * 1995-09-12 1997-12-09 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021126A1 (en) * 1993-03-18 1994-09-29 Ludwig Institute For Cancer Research Nucleic acid coding for a tumor rejection antigen precursor
WO1997026535A1 (en) * 1996-01-17 1997-07-24 Ludwig Institute For Cancer Research Isolated tyrosinase derived peptides and uses thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRUGGEN VAN DER P ET AL: "A GENE ENCODING AN ANTIGEN RECOGNIZED BY CYTOLYTIC T LYMPHOCYTES ON A HUMAN MELANOMA", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 254, 13 December 1991 (1991-12-13), pages 1643 - 1647, XP000604921, ISSN: 0036-8075 *
LAWENDOWSKI CARLA A ET AL: "Solid-phase epitope recovery: A high throughput method for antigen identification and epitope optimization.", JOURNAL OF IMMUNOLOGY, vol. 169, no. 5, 1 September 2002 (2002-09-01), September 1, 2002, pages 2414 - 2421, XP002223475, ISSN: 0022-1767 *
See also references of WO9937797A1 *
SETTE ET AL: "The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 153, no. 12, 1994, pages 5586 - 5592, XP002088728, ISSN: 0022-1767 *
WOELFEL T ET AL: "A P16INK4A-INSENSITIVE CDK4 MUTANT TARGETED BY CYTOLYTIC T LYMPHOCYTES IN A HUMAN MELANOMA", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 269, no. 5228, 1 September 1995 (1995-09-01), pages 1281 - 1284, XP001093623, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
AU2241499A (en) 1999-08-09
JP2002500891A (ja) 2002-01-15
EP1051507A1 (de) 2000-11-15
AU761256B2 (en) 2003-05-29
CA2318979A1 (en) 1999-07-29
WO1999037797A1 (en) 1999-07-29

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20000726

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 15/10 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 12N 5/06 B

Ipc: 7C 07H 21/04 B

Ipc: 7C 12N 15/11 B

Ipc: 7C 12P 21/00 B

Ipc: 7C 12P 19/34 A

A4 Supplementary search report drawn up and despatched

Effective date: 20021220

17Q First examination report despatched

Effective date: 20070208

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070619