EP1066061A4 - Verwendung eines dispersionsfaktors zur verstärkung der angiogenese - Google Patents

Verwendung eines dispersionsfaktors zur verstärkung der angiogenese

Info

Publication number
EP1066061A4
EP1066061A4 EP99914117A EP99914117A EP1066061A4 EP 1066061 A4 EP1066061 A4 EP 1066061A4 EP 99914117 A EP99914117 A EP 99914117A EP 99914117 A EP99914117 A EP 99914117A EP 1066061 A4 EP1066061 A4 EP 1066061A4
Authority
EP
European Patent Office
Prior art keywords
promote angiogenesis
dispersion factor
dispersion
factor
angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99914117A
Other languages
English (en)
French (fr)
Other versions
EP1066061A1 (de
Inventor
Itzhak D Goldberg
Eliot M Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Long Island Jewish Medical Center
Original Assignee
Long Island Jewish Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Long Island Jewish Medical Center filed Critical Long Island Jewish Medical Center
Publication of EP1066061A1 publication Critical patent/EP1066061A1/de
Publication of EP1066061A4 publication Critical patent/EP1066061A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP99914117A 1998-03-26 1999-03-26 Verwendung eines dispersionsfaktors zur verstärkung der angiogenese Withdrawn EP1066061A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4881398A 1998-03-26 1998-03-26
US48813 1998-03-26
PCT/US1999/006452 WO1999048537A1 (en) 1998-03-26 1999-03-26 Use of scatter factor to enhance angiogenesis

Publications (2)

Publication Number Publication Date
EP1066061A1 EP1066061A1 (de) 2001-01-10
EP1066061A4 true EP1066061A4 (de) 2003-01-08

Family

ID=21956589

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99914117A Withdrawn EP1066061A4 (de) 1998-03-26 1999-03-26 Verwendung eines dispersionsfaktors zur verstärkung der angiogenese

Country Status (6)

Country Link
EP (1) EP1066061A4 (de)
JP (1) JP2002507584A (de)
AU (1) AU3202999A (de)
CA (1) CA2326053A1 (de)
MX (1) MXPA00009440A (de)
WO (1) WO1999048537A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1114862A3 (de) * 1999-11-17 2003-08-06 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen
EP1176200A3 (de) * 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
US7247620B2 (en) 2001-05-09 2007-07-24 Anges Mg, Inc. Method of treating skin wounds with vectors encoding hepatocyte growth factor
NZ544797A (en) 2003-07-18 2011-04-29 Amgen Fremont Inc Specific antibodies that bind HGF and neutralise binding of HGF to met
FI20065514A0 (fi) * 2006-08-16 2006-08-16 Licentia Oy Aktivoidut fibroblastit kudosvaurioiden hoitamiseksi

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007824A1 (en) * 1995-08-29 1997-03-06 Sumitomo Pharmaceuticals Co., Ltd. Medicine comprising hgf gene
WO1997012629A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Improved angiogenesis using hepatocyte growth factor
US5652225A (en) * 1994-10-04 1997-07-29 St. Elizabeth's Medical Center Of Boston, Inc. Methods and products for nucleic acid delivery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652225A (en) * 1994-10-04 1997-07-29 St. Elizabeth's Medical Center Of Boston, Inc. Methods and products for nucleic acid delivery
WO1997007824A1 (en) * 1995-08-29 1997-03-06 Sumitomo Pharmaceuticals Co., Ltd. Medicine comprising hgf gene
EP0847757A1 (de) * 1995-08-29 1998-06-17 Sumitomo Pharmaceuticals Company, Limited Ein medikament,das das hgf gen enthält
WO1997012629A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Improved angiogenesis using hepatocyte growth factor

Non-Patent Citations (18)

* Cited by examiner, † Cited by third party
Title
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 199, no. 3, 1994, pages 1453 - 1460, ISSN: 0006-291X *
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 222, no. 1, 1996, pages 101 - 106, ISSN: 0006-291X *
CIRCULATION, vol. 92, no. 8 SUPPL., 1995, 68th Scientific Session of the American Heart Association;Anaheim, California, USA; November 13-16, 1995, pages I748, ISSN: 0009-7322 *
CIRCULATION, vol. 94, no. 8 SUPPL., 1996, 69th Scientific Sessions of the American Heart Association;New Orleans, Louisiana, USA; November 10-13, 1996, pages I463, ISSN: 0009-7322 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1994, WATANABE SUMIO ET AL: "Hepatocyte growth factor accelerates the wound repair of cultured gastric mucosal cells.", XP002219961, Database accession no. PREV199497222079 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, VAN BELLE ERIC ET AL: "Scatter factor stimulates angiogenesis in a rabbit model of hindlimb ischemia.", XP002219968, Database accession no. PREV199698586061 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, HAYASHI SHIN-ISHIRO ET AL: "Hypoxia down-regulated a novel angiogenic growth factor, hepatocyte growth factor (HGF) in human vascular cells, and transfection of HGF gene rescued endothelial cell death induced by hypoxia.", XP002219967, Database accession no. PREV199799303954 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, KATO KAZUYA ET AL: "Effect of hepatocyte growth factor on the proliferation of intrasplenically transplanted hepatocytes in rats.", XP002219959, Database accession no. PREV199699010900 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1997, LATERRA JOHN ET AL: "Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.", XP002219957, Database accession no. PREV199799551720 *
DATABASE MEDLINE [online] BUSSOLINO ET AL: "Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth", XP002219958, Database accession no. NLM1383237 *
DATABASE MEDLINE [online] KIM ET AL: "Enhanced survival of transgenic hepatocytes expressing hepatocyte growth factor in hepatocyte tissue engineering", XP002219960, Database accession no. NLM9123555 *
GRANT D S ET AL: "SCATTER FACTOR INDUCES BLOOD VESSEL FORMATION IN VIVO", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 90, March 1993 (1993-03-01), pages 1937 - 1941, XP002935422, ISSN: 0027-8424 *
LABORATORY INVESTIGATION, vol. 76, no. 4, 1997, pages 565 - 577, ISSN: 0023-6837 *
ROSEN E M ET AL: "SCATTER FACTOR AND ANGIOGENESIS", ADVANCES IN CANCER RESEARCH, ACADEMIC PRESS, LONDON, GB, vol. 67, 1995, pages 257 - 279, XP000615858, ISSN: 0065-230X *
See also references of WO9948537A1 *
THE JOURNAL OF CELL BIOLOGY, vol. 119, 1992, pages 629 - 641 *
TRANSPLANTATION PROCEEDINGS, vol. 29, 1997, pages 858 - 860 *
UEDA H ET AL: "IN VIVO GENE TRANSFECTION OF HEPATOCYTE GROWTH FACTOR ATTENUATES ISCHEMIA-REPERFUSION INJURY IN THE HEART: EVIDENCE FOR A ROLE OF HGF IN ENDOGENOUS MYOCARDIAL PROTECTION", CIRCULATION, AMERICAN HEART ASSOCIATION, DALLAS, TX, US, vol. 96, no. 8, 1997, pages 1619, XP002936330, ISSN: 0009-7322 *

Also Published As

Publication number Publication date
JP2002507584A (ja) 2002-03-12
CA2326053A1 (en) 1999-09-30
WO1999048537A1 (en) 1999-09-30
EP1066061A1 (de) 2001-01-10
MXPA00009440A (es) 2003-04-22
AU3202999A (en) 1999-10-18

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