EP1066272A4 - Neue verbindungen, die im komplement-, koagulat- und kallikrein-reaktionsweg nützlich sind und verfahren zu ihrer herstellung - Google Patents

Neue verbindungen, die im komplement-, koagulat- und kallikrein-reaktionsweg nützlich sind und verfahren zu ihrer herstellung

Info

Publication number
EP1066272A4
EP1066272A4 EP98926184A EP98926184A EP1066272A4 EP 1066272 A4 EP1066272 A4 EP 1066272A4 EP 98926184 A EP98926184 A EP 98926184A EP 98926184 A EP98926184 A EP 98926184A EP 1066272 A4 EP1066272 A4 EP 1066272A4
Authority
EP
European Patent Office
Prior art keywords
coagulat
complement
preparation
novel compounds
compounds useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98926184A
Other languages
English (en)
French (fr)
Other versions
EP1066272A1 (de
Inventor
Yarlagadda S Babu
J Claude Bennett
Shri Niwas
R Scott Rowland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocryst Pharmaceuticals Inc
Original Assignee
Biocryst Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocryst Pharmaceuticals Inc filed Critical Biocryst Pharmaceuticals Inc
Priority claimed from PCT/US1998/011255 external-priority patent/WO1998055471A1/en
Publication of EP1066272A1 publication Critical patent/EP1066272A1/de
Publication of EP1066272A4 publication Critical patent/EP1066272A4/de
Withdrawn legal-status Critical Current

Links

EP98926184A 1998-03-27 1998-06-03 Neue verbindungen, die im komplement-, koagulat- und kallikrein-reaktionsweg nützlich sind und verfahren zu ihrer herstellung Withdrawn EP1066272A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7966998P 1998-03-27 1998-03-27
US79669P 1998-03-27
PCT/US1998/011255 WO1998055471A1 (en) 1997-06-03 1998-06-03 Novel compounds useful in the complement, coagulat and kallikrein pathways and method for their preparation

Publications (2)

Publication Number Publication Date
EP1066272A1 EP1066272A1 (de) 2001-01-10
EP1066272A4 true EP1066272A4 (de) 2002-03-13

Family

ID=22152046

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98926184A Withdrawn EP1066272A4 (de) 1998-03-27 1998-06-03 Neue verbindungen, die im komplement-, koagulat- und kallikrein-reaktionsweg nützlich sind und verfahren zu ihrer herstellung

Country Status (1)

Country Link
EP (1) EP1066272A4 (de)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454338A (en) * 1980-09-16 1984-06-12 Torii & Co., Ltd. Amidine compound
US4490388A (en) * 1981-02-27 1984-12-25 Torii & Co., Ltd. Amidine compound and anticomplement agent comprising same
US4596822A (en) * 1984-08-20 1986-06-24 Georgia Tech Research Corporation Heterocyclic inhibitors of serine proteases
JPS61286361A (ja) * 1985-06-14 1986-12-16 Torii Yakuhin Kk アミジン誘導体
US5281721A (en) * 1984-08-20 1994-01-25 Georgia Tech Research Corporation Heterocyclic inhibitors of serine proteases
EP0798295A1 (de) * 1994-12-02 1997-10-01 Yamanouchi Pharmaceutical Co. Ltd. Neue amidinonaphthyl-derivate und deren salze
JPH10101556A (ja) * 1996-09-27 1998-04-21 Ono Pharmaceut Co Ltd ファクターｄ阻害剤

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454338A (en) * 1980-09-16 1984-06-12 Torii & Co., Ltd. Amidine compound
US4490388A (en) * 1981-02-27 1984-12-25 Torii & Co., Ltd. Amidine compound and anticomplement agent comprising same
US4596822A (en) * 1984-08-20 1986-06-24 Georgia Tech Research Corporation Heterocyclic inhibitors of serine proteases
US5281721A (en) * 1984-08-20 1994-01-25 Georgia Tech Research Corporation Heterocyclic inhibitors of serine proteases
JPS61286361A (ja) * 1985-06-14 1986-12-16 Torii Yakuhin Kk アミジン誘導体
EP0798295A1 (de) * 1994-12-02 1997-10-01 Yamanouchi Pharmaceutical Co. Ltd. Neue amidinonaphthyl-derivate und deren salze
JPH10101556A (ja) * 1996-09-27 1998-04-21 Ono Pharmaceut Co Ltd ファクターｄ阻害剤

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
IWANOWICZ E J ET AL: "Derivatives of 5-amidine indole as inhibitors of thrombin catalytic activity", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 6, no. 12, 18 June 1996 (1996-06-18), pages 1339 - 1344, XP004134837, ISSN: 0960-894X *
PATENT ABSTRACTS OF JAPAN vol. 011, no. 159 (C - 423) 22 May 1987 (1987-05-22) *
PATENT ABSTRACTS OF JAPAN vol. 1998, no. 09 31 July 1998 (1998-07-31) *
See also references of WO9855471A1 *
TAKUO AOYAMA ET AL: "Synthesis and structure-Activity study of protease inhibitors", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN. TOKYO, JP, vol. 33, no. 4, 1985, pages 1458 - 1471, XP002110067, ISSN: 0009-2363 *

Also Published As

Publication number Publication date
EP1066272A1 (de) 2001-01-10

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