EP1109829A4 - Proteine 3 de fixation latente au facteur beta de croissance de transformation humain - Google Patents

Proteine 3 de fixation latente au facteur beta de croissance de transformation humain

Info

Publication number
EP1109829A4
EP1109829A4 EP99946639A EP99946639A EP1109829A4 EP 1109829 A4 EP1109829 A4 EP 1109829A4 EP 99946639 A EP99946639 A EP 99946639A EP 99946639 A EP99946639 A EP 99946639A EP 1109829 A4 EP1109829 A4 EP 1109829A4
Authority
EP
European Patent Office
Prior art keywords
growth factor
binding protein
transforming growth
factor beta
beta binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99946639A
Other languages
German (de)
English (en)
Other versions
EP1109829A1 (fr
Inventor
Brian Taylor Edmonds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP1109829A1 publication Critical patent/EP1109829A1/fr
Publication of EP1109829A4 publication Critical patent/EP1109829A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP99946639A 1998-09-01 1999-08-30 Proteine 3 de fixation latente au facteur beta de croissance de transformation humain Withdrawn EP1109829A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9876698P 1998-09-01 1998-09-01
US98766P 1998-09-01
PCT/US1999/019436 WO2000012551A1 (fr) 1998-09-01 1999-08-30 PROTEINE 3 DE FIXATION LATENTE AU FACTEUR $G(b) DE CROISSANCE DE TRANSFORMATION HUMAIN

Publications (2)

Publication Number Publication Date
EP1109829A1 EP1109829A1 (fr) 2001-06-27
EP1109829A4 true EP1109829A4 (fr) 2003-01-02

Family

ID=22270787

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99946639A Withdrawn EP1109829A4 (fr) 1998-09-01 1999-08-30 Proteine 3 de fixation latente au facteur beta de croissance de transformation humain

Country Status (7)

Country Link
EP (1) EP1109829A4 (fr)
JP (1) JP2002535957A (fr)
AU (1) AU5900799A (fr)
CA (1) CA2341308A1 (fr)
HU (1) HUP0103201A2 (fr)
IL (1) IL141610A0 (fr)
WO (1) WO2000012551A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GONG W ET AL: "ISOFORMS AND SPLICE VARIANT OF TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN IN RAT HEPATIC STELLATE CELLS", GASTROENTEROLOGY, SAUNDERS, PHILADELPHIA, PA,, US, vol. 114, 1998, pages 352 - 363, XP002926967, ISSN: 0016-5085 *
MICHEL KRISTIN ET AL: "Analysis of the expression pattern of the latent transforming growth factor beta binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region.", HEPATOLOGY, vol. 27, no. 6, June 1998 (1998-06-01), pages 1592 - 1599, XP001117830, ISSN: 0270-9139 *
See also references of WO0012551A1 *
YIN W ET AL: "ISOLATION OF A NOVEL LATEN TRANFORMING GROWTH FACTOR-BETA BINDING PROTEIN GENE (LTBP-3)", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 270, no. 17, 28 April 1995 (1995-04-28), pages 10147 - 10160, XP002926966, ISSN: 0021-9258 *
YIN WUSHAN ET AL: "Alternative splicing of LTBP-3.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 245, no. 2, 17 April 1998 (1998-04-17), pages 454 - 458, XP002218577, ISSN: 0006-291X *

Also Published As

Publication number Publication date
EP1109829A1 (fr) 2001-06-27
WO2000012551A1 (fr) 2000-03-09
HUP0103201A2 (hu) 2001-12-28
CA2341308A1 (fr) 2000-03-09
IL141610A0 (en) 2002-03-10
JP2002535957A (ja) 2002-10-29
AU5900799A (en) 2000-03-21

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