EP1126831A4 - Methoden zur behandlung der insulinresistenz durch stickstoffmonoxyd der leber - Google Patents

Methoden zur behandlung der insulinresistenz durch stickstoffmonoxyd der leber

Info

Publication number
EP1126831A4
EP1126831A4 EP99951765A EP99951765A EP1126831A4 EP 1126831 A4 EP1126831 A4 EP 1126831A4 EP 99951765 A EP99951765 A EP 99951765A EP 99951765 A EP99951765 A EP 99951765A EP 1126831 A4 EP1126831 A4 EP 1126831A4
Authority
EP
European Patent Office
Prior art keywords
nitric oxide
insulin resistance
treating insulin
hepatic nitric
hepatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99951765A
Other languages
English (en)
French (fr)
Other versions
EP1126831A1 (de
Inventor
Wilfred Wayne Lautt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diamedica Therapeutics Inc
Original Assignee
Diamedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diamedica Inc filed Critical Diamedica Inc
Publication of EP1126831A1 publication Critical patent/EP1126831A1/de
Publication of EP1126831A4 publication Critical patent/EP1126831A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99951765A 1998-10-06 1999-10-05 Methoden zur behandlung der insulinresistenz durch stickstoffmonoxyd der leber Withdrawn EP1126831A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10317098P 1998-10-06 1998-10-06
US103170P 1998-10-06
PCT/US1999/023098 WO2000019992A1 (en) 1998-10-06 1999-10-05 Method for treating insulin resistance through hepatic nitric oxide

Publications (2)

Publication Number Publication Date
EP1126831A1 EP1126831A1 (de) 2001-08-29
EP1126831A4 true EP1126831A4 (de) 2004-10-06

Family

ID=22293754

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99951765A Withdrawn EP1126831A4 (de) 1998-10-06 1999-10-05 Methoden zur behandlung der insulinresistenz durch stickstoffmonoxyd der leber

Country Status (3)

Country Link
EP (1) EP1126831A4 (de)
CA (1) CA2381095C (de)
WO (1) WO2000019992A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7622447B2 (en) * 2002-01-25 2009-11-24 Diamedica Inc. Use of glutathione synthesis stimulating compounds in reducing insulin resistance
US8673964B2 (en) 2004-05-20 2014-03-18 Diamedica Inc. Use of drug combinations for treating insulin resistance
EP2788078B1 (de) 2011-12-09 2020-09-02 Metavention, Inc. Therapeutische neuromodulation des hepatischen systems
AU2013230776B2 (en) 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Immune system neuromodulation and associated systems and methods
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
US20130323222A1 (en) 2012-06-04 2013-12-05 Matthew Charles Human tissue kallikrein 1 glycosylation isoforms
CA2913346A1 (en) 2013-06-05 2014-12-11 Metavention, Inc. Modulation of targeted nerve fibers
AU2015358385B2 (en) 2014-12-03 2020-09-03 Medtronic Ireland Manufacturing Unlimited Company Systems and methods for modulating nerves or other tissue
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
AU2018230478B2 (en) 2017-03-09 2025-01-23 Diamedica Inc. Dosage forms of tissue kallikrein 1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910316A (en) * 1992-08-24 1999-06-08 The United States Of America, As Represented By The Department Of Health And Human Services Use of nitric oxide-releasing agents to treat impotency
GB9510037D0 (en) * 1995-05-18 1995-07-12 Sandoz Nutrition Ltd Improvements in or relating to organic compounds
US5906987A (en) * 1997-03-10 1999-05-25 Schering Aktiengesellschaft And Board Of Regents Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in combination with androgens and/or aromatase inhibitors

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
GOTOH M ET AL: "VAGALLY MEDIATED INSULIN SECRETION BY STIMULATION OF BRAIN CHOLINERGIC NEURONS WITH NEOSTIGMINE IN BILATERAL ADRENALECTOMIZED RATS", BRAIN RESEARCH, AMSTERDAM, NL, vol. 493, no. 1, 24 July 1989 (1989-07-24), pages 97 - 102, XP009011022, ISSN: 0006-8993 *
PARISSA SANDRI AND ALL.: "Blockade of Nitric Oxide Production in the Liver Causes Insulin Resistance", PROCEEDINGS OF THE WESTERN PHARMACOLOGICAL SOCIETY, vol. 41, 1 August 1998 (1998-08-01), pages 37 - 38, XP002292125 *
RIO DEL G ET AL: "CHOLINERGIC ENHANCEMENT BY PYRIDOSTIGMINE INCREASES THE INSULIN RESPONSE TO GLUCOSE LOAD IN OBESE PATIENTS BUT NOT IN NORMAL SUBJECTS", INTERNATIONAL JOURNAL OF OBESITY, NEWMAN PUBLISHING, LONDON, GB, vol. 21, no. 12, December 1997 (1997-12-01), pages 1111 - 1114, XP009011020, ISSN: 0307-0565 *
See also references of WO0019992A1 *
SZABO O ET AL: "NEUROPHARMACOLOGICAL CHARACTERIZATION OF INSULIN-SENSITIVE CNS GLUCOREGULATOR", AMERICAN JOURNAL OF PHYSIOLOGY, AMERICAN PHYSIOLOGICAL SOCIETY, BETHESDA, MD, US, vol. 229, no. 3, September 1975 (1975-09-01), pages 663 - 668, XP009011092, ISSN: 0002-9513 *
XIE H ET AL: "INSULIN RESISTANCE CAUSED BY HEPATIC CHOLINERGIC INTERRUPTION AN REVERSED BY ACETYLCHOLINE ADMINISTRATION", AMERICAN JOURNAL OF PHYSIOLOGY, AMERICAN PHYSIOLOGICAL SOCIETY, BETHESDA, MD, US, vol. 271, no. 3, PART 1, 1996, pages E587 - E592, XP009011012, ISSN: 0002-9513 *

Also Published As

Publication number Publication date
WO2000019992A1 (en) 2000-04-13
CA2381095A1 (en) 2000-04-13
CA2381095C (en) 2012-08-14
EP1126831A1 (de) 2001-08-29
WO2000019992A9 (en) 2000-09-21

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Owner name: KOHN, KENNETH I.

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