EP1128832A4 - Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungen - Google Patents
Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungenInfo
- Publication number
- EP1128832A4 EP1128832A4 EP99942288A EP99942288A EP1128832A4 EP 1128832 A4 EP1128832 A4 EP 1128832A4 EP 99942288 A EP99942288 A EP 99942288A EP 99942288 A EP99942288 A EP 99942288A EP 1128832 A4 EP1128832 A4 EP 1128832A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- treating
- compounds
- methods
- viral infections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9747698P | 1998-08-21 | 1998-08-21 | |
| US97476P | 1998-08-21 | ||
| US11321298P | 1998-12-22 | 1998-12-22 | |
| US113212P | 1998-12-22 | ||
| US11932899P | 1999-02-09 | 1999-02-09 | |
| US119328P | 1999-02-09 | ||
| US13558699P | 1999-05-24 | 1999-05-24 | |
| US13558599P | 1999-05-24 | 1999-05-24 | |
| US135585P | 1999-05-24 | ||
| US135586P | 1999-05-24 | ||
| PCT/US1999/018785 WO2000010573A1 (en) | 1998-08-21 | 1999-08-19 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1128832A1 EP1128832A1 (de) | 2001-09-05 |
| EP1128832A4 true EP1128832A4 (de) | 2003-03-05 |
Family
ID=27536838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99942288A Withdrawn EP1128832A4 (de) | 1998-08-21 | 1999-08-19 | Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungen |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1128832A4 (de) |
| JP (1) | JP2002523371A (de) |
| KR (1) | KR20010099623A (de) |
| CN (1) | CN1325309A (de) |
| AU (1) | AU743411B2 (de) |
| BR (1) | BR9913157A (de) |
| CA (1) | CA2341970A1 (de) |
| ID (1) | ID27787A (de) |
| IL (1) | IL141456A0 (de) |
| WO (1) | WO2000010573A1 (de) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200103562T2 (tr) * | 1999-06-10 | 2002-04-22 | Warner-Lambert Company | Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri |
| CN1384825A (zh) | 1999-08-31 | 2002-12-11 | 马克西亚药品公司 | 亚苄基－噻唑烷二酮及其类似物以及它们在治疗糖尿病中的应用 |
| WO2001077091A2 (en) * | 2000-04-05 | 2001-10-18 | Tularik Inc. | Ns5b hcv polymerase inhibitors |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| AU7622500A (en) * | 2000-09-29 | 2002-07-01 | Neurogen Corp | High affinity small molecule c5a receptor modulators |
| BR0207846A (pt) | 2001-03-07 | 2005-09-13 | Incyte San Diego Inc | Derivados heterocìclicos para o tratamento de câncer e outras doenças proliferativas |
| JP2004523571A (ja) | 2001-03-08 | 2004-08-05 | マキシア・ファーマシューティカルズ・インコーポレイテッド | Ｒｘｒ活性化分子 |
| GB2376944A (en) * | 2001-05-18 | 2002-12-31 | Pantherix Ltd | Polycyclic heterocyclic compounds and their therapeutic use |
| CA2448737C (en) | 2001-07-20 | 2010-06-01 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| EP2335700A1 (de) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C Virus Polymerase Inhibitoren mit heterobicylischer Struktur |
| US20030134853A1 (en) | 2001-09-26 | 2003-07-17 | Priestley Eldon Scott | Compounds useful for treating hepatitis C virus |
| JP2005513026A (ja) | 2001-11-15 | 2005-05-12 | インサイト サン ディエゴ インコーポレイテッド | 高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環 |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| GB2387172A (en) * | 2002-03-28 | 2003-10-08 | Pantherix Ltd | [(Aryl-/arylthio-)aryl]methylene substituted azole & azine derivatives and their therapeutic use as antibacterials |
| US20060281798A1 (en) * | 2002-05-17 | 2006-12-14 | Qlt Inc. | Methods of using thiazolidinedithione derivatives |
| ES2315568T3 (es) | 2002-05-20 | 2009-04-01 | Bristol-Myers Squibb Company | Inhibidores del virus de la hepatitis c basados en cicloalquilo p1' sustituido. |
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| PL215228B1 (pl) | 2002-05-20 | 2013-11-29 | Bristol Myers Squibb Co | Zwiazki tripeptydowe, ich zastosowanie i kompozycja farmaceutyczna je zawierajaca oraz jej zastosowanie |
| AU2003248535A1 (en) | 2002-05-20 | 2003-12-12 | Bristol-Myers Squibb Company | Heterocyclicsulfonamide hepatitis c virus inhibitors |
| BR0305259A (pt) | 2002-07-01 | 2004-10-05 | Upjohn Co | Inibidores de hcv ns5b polimerase |
| US7041690B2 (en) | 2002-07-01 | 2006-05-09 | Pharmacia & Upjohn Company, Llc | Inhibitors of HCV NS5B polymerase |
| FR2845000B1 (fr) | 2002-09-27 | 2005-05-27 | Oreal | Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute |
| US7235573B2 (en) | 2002-09-30 | 2007-06-26 | The Regents Of The University Of California | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors |
| BR0314943A (pt) * | 2002-09-30 | 2005-08-02 | Univ California | Inibidores da proteìna reguladora da condutância transmembrana da fibrose cìstica e usos destes |
| EP1597255A1 (de) * | 2002-11-13 | 2005-11-23 | Rigel Pharmaceuticals, Inc. | Rhodanin-derivate und sie enthaltende pharmazeutische zusammensetzungen |
| ATE422895T1 (de) | 2003-04-16 | 2009-03-15 | Bristol Myers Squibb Co | Makrocyclische isochinolinpeptidinhibitoren des hepatitis-c-virus |
| DE602004025708D1 (de) * | 2003-07-11 | 2010-04-08 | Proteologics Inc | Ubiquitin-ligase-hemmer und verwandte verfahren |
| FR2858324A1 (fr) * | 2003-07-30 | 2005-02-04 | Centre Nat Rech Scient | Nouveaux composes antibiotiques, compositions pharmaceutiques les contenant et leurs utilisations |
| US7112601B2 (en) | 2003-09-11 | 2006-09-26 | Bristol-Myers Squibb Company | Cycloalkyl heterocycles for treating hepatitis C virus |
| WO2005041951A2 (en) * | 2003-10-28 | 2005-05-12 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives for use as antiviral agents |
| US7026339B2 (en) | 2003-11-07 | 2006-04-11 | Fan Yang | Inhibitors of HCV NS5B polymerase |
| US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN1922174A (zh) | 2004-02-20 | 2007-02-28 | 贝林格尔·英格海姆国际有限公司 | 病毒聚合酶抑制剂 |
| US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
| WO2005080399A1 (ja) | 2004-02-24 | 2005-09-01 | Japan Tobacco Inc. | ４環縮合複素環化合物及びそのｈｃｖポリメラーゼ阻害剤としての利用 |
| US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
| MX2007013415A (es) | 2005-05-04 | 2008-01-15 | Hoffmann La Roche | Compuestos antivirales heterociclicos. |
| EP1896033A4 (de) * | 2005-06-15 | 2010-12-22 | New York Blood Ct Inc | Antivirale zusammensetzungen mit heterocyclischen substituierten phenylfuranen und verwandte verbindungen |
| US8017612B2 (en) | 2006-04-18 | 2011-09-13 | Japan Tobacco Inc. | Piperazine compound and use thereof as a HCV polymerase inhibitor |
| WO2007131168A2 (en) * | 2006-05-04 | 2007-11-15 | Institute For Hepatitis And Virus Research | Inhibitors of secretion of hepatitis b virus antigens for treatment of a chronic hepatitis virus |
| HRP20110193T1 (hr) | 2006-10-10 | 2011-05-31 | Medivir Ab | Inhibitor hcv nukleozida |
| WO2008082537A2 (en) * | 2006-12-19 | 2008-07-10 | The General Hospital Corporation | Compounds for modulating integrin cd11b/cd18 |
| AR068794A1 (es) | 2007-06-29 | 2009-12-09 | Gilead Sciences Inc | Compuestos antivirales |
| NZ582096A (en) | 2007-06-29 | 2012-05-25 | Gilead Sciences Inc | Antiviral compounds that inhibit hepatitis c virus (hcv) |
| JP2011502998A (ja) * | 2007-11-01 | 2011-01-27 | ザ ユーエイビー リサーチ ファウンデイション | ウイルス感染の治療および予防 |
| EP2234608A2 (de) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzymhemmer mit metallbindenden teilen in kombination mit targeting-teilen |
| US7947717B2 (en) | 2008-07-18 | 2011-05-24 | Burnham Institute For Medical Research | Inhibitors of lethal factor protease |
| WO2010065668A1 (en) | 2008-12-03 | 2010-06-10 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| AU2009322393B2 (en) | 2008-12-03 | 2017-02-02 | Presidio Pharmaceuticals, Inc. | Inhibitors of HCV NS5A |
| EA201190224A1 (ru) | 2009-03-27 | 2012-03-30 | Пресидио Фармасьютикалс, Инк. | Ингибиторы гепатита c, содержащие конденсированные кольца |
| NZ599373A (en) | 2009-11-14 | 2013-04-26 | Hoffmann La Roche | Biomarkers for predicting rapid response to hcv treatment |
| AU2010326781A1 (en) | 2009-12-02 | 2012-04-19 | F. Hoffmann-La Roche Ag | Biomarkers for predicting sustained response to HCV treatment |
| WO2011075784A1 (en) * | 2009-12-23 | 2011-06-30 | Peter Maccallum Cancer Institute | Compounds, preparations and uses thereof |
| CA2800509A1 (en) | 2010-05-24 | 2011-12-01 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| KR101159000B1 (ko) | 2010-06-18 | 2012-06-21 | (주) 에빅스젠 | 신규한 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 ａｉｄｓ 예방 또는 치료용 약학 조성물 |
| US9023876B2 (en) | 2010-07-08 | 2015-05-05 | Adhaere Pharmaceuticals, Inc. | Compounds and methods for regulating integrins |
| US9255088B2 (en) | 2010-08-11 | 2016-02-09 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
| WO2012123298A1 (en) | 2011-03-11 | 2012-09-20 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| WO2012175581A1 (en) | 2011-06-24 | 2012-12-27 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| KR101621181B1 (ko) | 2011-10-10 | 2016-05-13 | 에프. 호프만-라 로슈 아게 | 항바이러스성 화합물 |
| CN103987723B (zh) | 2011-12-16 | 2017-03-01 | 弗·哈夫曼-拉罗切有限公司 | Hcv ns5a 的抑制剂 |
| EA024297B1 (ru) | 2011-12-20 | 2016-09-30 | Рибосайенс Ллк | 2',4'-дифтор-2'-метилзамещенные нуклеозидные производные в качестве ингибиторов репликации рнк вируса гепатита с |
| IN2014CN04530A (de) | 2011-12-20 | 2015-09-11 | Hoffmann La Roche | |
| CN104185624B (zh) | 2012-02-24 | 2016-10-12 | 弗·哈夫曼-拉罗切有限公司 | 抗病毒化合物 |
| US9598395B2 (en) | 2012-03-23 | 2017-03-21 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
| CA2882853C (en) | 2012-04-20 | 2021-11-23 | Vineet Gupta | Compounds and methods for regulating integrins |
| US20140010783A1 (en) | 2012-07-06 | 2014-01-09 | Hoffmann-La Roche Inc. | Antiviral compounds |
| MX2015009176A (es) | 2013-01-23 | 2015-11-09 | Hoffmann La Roche | Derivados de triazola antivirales. |
| WO2014135422A1 (en) | 2013-03-05 | 2014-09-12 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| RU2534613C2 (ru) | 2013-03-22 | 2014-11-27 | Александр Васильевич Иващенко | Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения |
| US20180200280A1 (en) | 2013-05-16 | 2018-07-19 | Riboscience Llc | 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication |
| AU2014265293B2 (en) | 2013-05-16 | 2019-07-18 | Riboscience Llc | 4'-Fluoro-2'-methyl substituted nucleoside derivatives |
| MX2015015781A (es) | 2013-05-16 | 2016-06-02 | Riboscience Llc | Derivados de nucleósido 4'-azido, 3'-deoxi-3'-fluoro sustituido. |
| EP3684374B1 (de) | 2017-09-21 | 2025-07-30 | Riboscience LLC | 4'-fluor-2'-methyl-substituierte nukleosidderivate als hemmer der hcv-rna-replikation |
| KR101893988B1 (ko) | 2018-05-16 | 2018-08-31 | (주)에빅스젠 | 로다닌 유도체를 함유하는 aids 예방 또는 치료용 약학 조성물 |
| WO2023161427A1 (en) | 2022-02-24 | 2023-08-31 | Eisbach Bio Gmbh | Viral combination therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (en) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates in the treatment of flavivirus infections |
| WO1998020013A1 (de) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Neue knoevenagel-kondensationsprodukte, verfahren zu deren herstellung und verwendung |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909467A (en) * | 1958-07-09 | 1959-10-20 | Us Vitamin Pharm Corp | 3-(d-alpha-methylphenethyl)-5-methyl-1, 3-oxazolidine-2, 4-dione |
| US3888984A (en) * | 1972-03-13 | 1975-06-10 | Lilly Industries Ltd | Oxazole and imidazole derivatives as antifungal agents |
| AU6610081A (en) * | 1980-01-24 | 1981-07-30 | Senju Pharmaceutical Co., Ltd. | Thiazolidine derivatives |
| US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| CA2153553A1 (en) * | 1994-07-13 | 1996-01-14 | Hidekazu Suzuki | Stable lipid emulsion |
| US5834466A (en) * | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
-
1999
- 1999-08-19 IL IL14145699A patent/IL141456A0/xx unknown
- 1999-08-19 ID IDW20010428A patent/ID27787A/id unknown
- 1999-08-19 WO PCT/US1999/018785 patent/WO2000010573A1/en not_active Ceased
- 1999-08-19 CA CA002341970A patent/CA2341970A1/en not_active Abandoned
- 1999-08-19 EP EP99942288A patent/EP1128832A4/de not_active Withdrawn
- 1999-08-19 AU AU55702/99A patent/AU743411B2/en not_active Ceased
- 1999-08-19 CN CN99812282A patent/CN1325309A/zh active Pending
- 1999-08-19 BR BR9913157-9A patent/BR9913157A/pt not_active Application Discontinuation
- 1999-08-19 JP JP2000565894A patent/JP2002523371A/ja active Pending
- 1999-08-19 KR KR1020017002117A patent/KR20010099623A/ko not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (en) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates in the treatment of flavivirus infections |
| WO1998020013A1 (de) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Neue knoevenagel-kondensationsprodukte, verfahren zu deren herstellung und verwendung |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO0010573A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| BR9913157A (pt) | 2001-05-15 |
| EP1128832A1 (de) | 2001-09-05 |
| AU743411B2 (en) | 2002-01-24 |
| ID27787A (id) | 2001-04-26 |
| CA2341970A1 (en) | 2000-03-02 |
| JP2002523371A (ja) | 2002-07-30 |
| IL141456A0 (en) | 2002-03-10 |
| KR20010099623A (ko) | 2001-11-09 |
| AU5570299A (en) | 2000-03-14 |
| CN1325309A (zh) | 2001-12-05 |
| WO2000010573A1 (en) | 2000-03-02 |
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