EP1140121A4 - Cryogranulation de la proteine c activee - Google Patents

Cryogranulation de la proteine c activee

Info

Publication number
EP1140121A4
EP1140121A4 EP99935947A EP99935947A EP1140121A4 EP 1140121 A4 EP1140121 A4 EP 1140121A4 EP 99935947 A EP99935947 A EP 99935947A EP 99935947 A EP99935947 A EP 99935947A EP 1140121 A4 EP1140121 A4 EP 1140121A4
Authority
EP
European Patent Office
Prior art keywords
cryogranulation
activated protein
protein
activated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99935947A
Other languages
German (de)
English (en)
Other versions
EP1140121A1 (fr
Inventor
Jeffrey Clayton Baker
Nancy Delores Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP1140121A1 publication Critical patent/EP1140121A1/fr
Publication of EP1140121A4 publication Critical patent/EP1140121A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
EP99935947A 1998-07-31 1999-07-26 Cryogranulation de la proteine c activee Withdrawn EP1140121A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9496998P 1998-07-31 1998-07-31
US94969P 1998-07-31
PCT/US1999/016937 WO2000006179A1 (fr) 1998-07-31 1999-07-26 Cryogranulation de la proteine c activee

Publications (2)

Publication Number Publication Date
EP1140121A1 EP1140121A1 (fr) 2001-10-10
EP1140121A4 true EP1140121A4 (fr) 2004-07-14

Family

ID=22248239

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99935947A Withdrawn EP1140121A4 (fr) 1998-07-31 1999-07-26 Cryogranulation de la proteine c activee

Country Status (5)

Country Link
EP (1) EP1140121A4 (fr)
JP (1) JP2003506006A (fr)
AU (1) AU5131699A (fr)
CA (1) CA2338766A1 (fr)
WO (1) WO2000006179A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007143A1 (fr) 1989-11-17 1991-05-30 Green Alan J Applicateur de fil dentaire
AUPR750501A0 (en) * 2001-09-05 2001-09-27 Gauci, Mark Products comprising quantum of bioparticles and method for production thereof
EP1697033B1 (fr) 2003-12-19 2011-04-13 Alk-Abelló A/S Procede de cryogranulation et de stockage d'allergènes
CN1894026B (zh) * 2003-12-19 2012-01-25 阿尔克-阿贝洛有限公司 用于活性药剂的低温制粒和贮藏的方法
US20120052102A1 (en) * 2009-03-06 2012-03-01 Linde Aktiengesellschaft Method for producing cosmetics
EP2496253B1 (fr) 2009-11-02 2019-01-09 MannKind Corporation Appareil et méthode de cryogranulation d'une composition pharmaceutique
ES2786506T3 (es) * 2012-08-01 2020-10-13 Zahra Tavakoli Composiciones congeladas fluidas que comprenden un agente terapéutico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516650A (en) * 1985-06-27 1996-05-14 Zymogenetics, Inc. Production of activated protein C
US5792835A (en) * 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
MY110664A (en) * 1992-05-21 1999-01-30 Lilly Co Eli Protein c derivatives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SCHMIDT D J ET AL: "CRYOGRANULATION: A POTENTIAL NEW FINAL PROCESS FOR BULK DRUG SUBSTANCES", BIOPHARM, CLEVELAND,OH, US, April 1997 (1997-04-01), pages 28,30,32, XP002914615 *
See also references of WO0006179A1 *

Also Published As

Publication number Publication date
CA2338766A1 (fr) 2000-02-10
JP2003506006A (ja) 2003-02-18
EP1140121A1 (fr) 2001-10-10
AU5131699A (en) 2000-02-21
WO2000006179A1 (fr) 2000-02-10

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20010131

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Effective date: 20041222