EP1146887A4 - Einen desmethylvancosaminrest enthaltende glykopeptidantibiotika, kombinatorische bibliotheken derselben und verfahren zu deren herstellung - Google Patents

Einen desmethylvancosaminrest enthaltende glykopeptidantibiotika, kombinatorische bibliotheken derselben und verfahren zu deren herstellung

Info

Publication number
EP1146887A4
EP1146887A4 EP00903240A EP00903240A EP1146887A4 EP 1146887 A4 EP1146887 A4 EP 1146887A4 EP 00903240 A EP00903240 A EP 00903240A EP 00903240 A EP00903240 A EP 00903240A EP 1146887 A4 EP1146887 A4 EP 1146887A4
Authority
EP
European Patent Office
Prior art keywords
desmethylvancosamine
residue
methods
making same
glycopeptide antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00903240A
Other languages
English (en)
French (fr)
Other versions
EP1146887A1 (de
Inventor
Daniel Kahne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Princeton University filed Critical Princeton University
Publication of EP1146887A1 publication Critical patent/EP1146887A1/de
Publication of EP1146887A4 publication Critical patent/EP1146887A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00903240A 1999-01-12 2000-01-12 Einen desmethylvancosaminrest enthaltende glykopeptidantibiotika, kombinatorische bibliotheken derselben und verfahren zu deren herstellung Withdrawn EP1146887A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11559499P 1999-01-12 1999-01-12
US115594P 1999-01-12
PCT/US2000/000650 WO2000041710A1 (en) 1999-01-12 2000-01-12 Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same

Publications (2)

Publication Number Publication Date
EP1146887A1 EP1146887A1 (de) 2001-10-24
EP1146887A4 true EP1146887A4 (de) 2003-05-07

Family

ID=22362330

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00903240A Withdrawn EP1146887A4 (de) 1999-01-12 2000-01-12 Einen desmethylvancosaminrest enthaltende glykopeptidantibiotika, kombinatorische bibliotheken derselben und verfahren zu deren herstellung

Country Status (3)

Country Link
EP (1) EP1146887A4 (de)
AU (1) AU2501700A (de)
WO (1) WO2000041710A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2337103A1 (en) * 1998-07-14 2000-01-27 Robert Kerns Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CA2372392A1 (en) * 1999-05-19 2000-11-23 Min Ge Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CN101959900A (zh) * 2007-12-26 2011-01-26 盐野义制药株式会社 糖肽类抗生素糖基化衍生物
CN115317600A (zh) * 2015-01-16 2022-11-11 硕腾服务有限责任公司 口蹄疫疫苗

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742045A (en) * 1986-07-30 1988-05-03 Smithkline Beckman Corporation Glycopeptide antibiotics
US4882313A (en) * 1987-07-31 1989-11-21 Smithkline Beckman Corporation Carboxamide derivatives of glycopeptides
DE4013077A1 (de) * 1990-04-25 1991-10-31 Hoechst Ag Verfahren zur glycosidasekatalysierten synthese von glycokonjugaten

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MALABARBA A ET AL: "STRUCTURAL MODIFICATIONS OF GLYCOPEPTIDE ANTIBIOTICS", MEDICINAL RESEARCH REVIEWS, NEW YORK, NY, US, vol. 17, no. 1, 1997, pages 69 - 137, XP000985926, ISSN: 0198-6325 *
MALABARBA A NICAS TI CIABATTI R: "Glycopeptide resistance in multiple antibiotic-resistant Gram-positive bacteria: a current challenge for novel semi-synthetic glycopeptide derivatives", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 32, no. 6, 1 June 1997 (1997-06-01), pages 459 - 478, XP004088458, ISSN: 0223-5234 *
See also references of WO0041710A1 *

Also Published As

Publication number Publication date
WO2000041710A1 (en) 2000-07-20
EP1146887A1 (de) 2001-10-24
AU2501700A (en) 2000-08-01
WO2000041710A9 (en) 2001-11-22

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Legal Events

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