EP1174407A3 - Procédé de préparation de 6,6-diméthylhept-1-en-4-yn-3-ol - Google Patents

Procédé de préparation de 6,6-diméthylhept-1-en-4-yn-3-ol Download PDF

Info

Publication number: EP1174407A3
Authority: EP; European Patent Office
Prior art keywords: dimethylhept; preparation; reacting; butylacetylide; butylacetylene
Prior art date: 2000-07-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP01305608A

Other languages

German (de)

English (en)

Other versions

EP1174407A2 (fr

Inventor

Joseph Kaspi

Oded Friedman

Edna Danon

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wavelength Pharmaceuticals Ltd

Original Assignee

Chemagis Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-18

Filing date

2001-06-27

Publication date

2004-01-07

2001-06-27 Application filed by Chemagis Ltd filed Critical Chemagis Ltd

2002-01-23 Publication of EP1174407A2 publication Critical patent/EP1174407A2/fr

2004-01-07 Publication of EP1174407A3 publication Critical patent/EP1174407A3/fr

Status Withdrawn legal-status Critical Current

Links

MOWPBNFGGOHZRW-UHFFFAOYSA-N 6,6-dimethylhept-1-en-4-yn-3-ol Chemical compound CC(C)(C)C#CC(O)C=C MOWPBNFGGOHZRW-UHFFFAOYSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 abstract 2
TXBOKWJUQMJRAO-UHFFFAOYSA-N 3,3-dimethylbut-1-yne Chemical compound CC(C)(C)C#[C-] TXBOKWJUQMJRAO-UHFFFAOYSA-N 0.000 abstract 1
PPWNCLVNXGCGAF-UHFFFAOYSA-N 3,3-dimethylbut-1-yne Chemical group CC(C)(C)C#C PPWNCLVNXGCGAF-UHFFFAOYSA-N 0.000 abstract 1
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
VWWMOACCGFHMEV-UHFFFAOYSA-N dicarbide(2-) Chemical compound [C-]#[C-] VWWMOACCGFHMEV-UHFFFAOYSA-N 0.000 abstract 1
229910052744 lithium Inorganic materials 0.000 abstract 1
150000002902 organometallic compounds Chemical class 0.000 abstract 1
238000010791 quenching Methods 0.000 abstract 1
230000000171 quenching effect Effects 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EP01305608A 2000-07-18 2001-06-27 Procédé de préparation de 6,6-diméthylhept-1-en-4-yn-3-ol Withdrawn EP1174407A3 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL13736400A IL137364A (en)	2000-07-18	2000-07-18	Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
IL13736400		2000-07-18

Publications (2)

Publication Number	Publication Date
EP1174407A2 EP1174407A2 (fr)	2002-01-23
EP1174407A3 true EP1174407A3 (fr)	2004-01-07

Family

ID=11074405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP01305608A Withdrawn EP1174407A3 (fr)	2000-07-18	2001-06-27	Procédé de préparation de 6,6-diméthylhept-1-en-4-yn-3-ol

Country Status (4)

Country	Link
US (1)	US6570044B2 (fr)
EP (1)	EP1174407A3 (fr)
CA (1)	CA2350394A1 (fr)
IL (1)	IL137364A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005110968A1 (fr) *	2004-05-14	2005-11-24	Hydex Chemicals Pvt Ltd.	Procede ameliore de preparation de chlorhydrate de terbinafine
US20060004230A1 (en) *	2004-06-30	2006-01-05	Joseph Kaspi	Process for the preparation of terbinafine and salts thereof
WO2007096904A2 (fr) *	2006-02-23	2007-08-30	Manne Satyanarayana Reddy	Procédé amélioré de préparation d'hydrochlorure de terbinafine et nouvelle forme cristallin de terbinafine
US8663177B1 (en)	2012-09-28	2014-03-04	Anal-Gesic LLC	Medication delivery, dosing and safety devices, systems and kits

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2783258A (en) *	1951-11-08	1957-02-26	Pfizer & Co C	Unsaturated organic compounds and their preparation
US4382951A (en) *	1980-12-15	1983-05-10	Sandoz Ltd.	Benzopyrane and benzothiopyrane derivatives useful as anti-mycotic agents
EP0341048A1 (fr) *	1988-05-06	1989-11-08	Sumitomo Chemical Company, Limited	Composé de pyrazole sa préparation et son utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CY1410A (en) *	1979-08-22	1988-04-22	Sandoz Ag	Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

2000
- 2000-07-18 IL IL13736400A patent/IL137364A/xx not_active IP Right Cessation
2001
- 2001-06-13 CA CA002350394A patent/CA2350394A1/fr not_active Abandoned
- 2001-06-27 EP EP01305608A patent/EP1174407A3/fr not_active Withdrawn
- 2001-07-17 US US09/906,105 patent/US6570044B2/en not_active Expired - Fee Related

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2783258A (en) *	1951-11-08	1957-02-26	Pfizer & Co C	Unsaturated organic compounds and their preparation
US4382951A (en) *	1980-12-15	1983-05-10	Sandoz Ltd.	Benzopyrane and benzothiopyrane derivatives useful as anti-mycotic agents
EP0341048A1 (fr) *	1988-05-06	1989-11-08	Sumitomo Chemical Company, Limited	Composé de pyrazole sa préparation et son utilisation

Also Published As

Publication number	Publication date
CA2350394A1 (fr)	2002-01-18
IL137364A (en)	2005-08-31
EP1174407A2 (fr)	2002-01-23
US6570044B2 (en)	2003-05-27
IL137364A0 (en)	2001-07-24
US20020016517A1 (en)	2002-02-07

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Legal Events

Date	Code	Title	Description
2001-12-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2002-01-23	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2002-01-23	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2003-11-21	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
2004-01-07	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2004-01-07	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2004-08-25	17P	Request for examination filed	Effective date: 20040628
2004-09-29	AKX	Designation fees paid	Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2005-07-14	GRAP	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOSNIGR1
2006-05-05	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2006-06-07	18D	Application deemed to be withdrawn	Effective date: 20051201