EP1180937A4 - Souches de bacteriophages utiles pour sauver des patients infectes par enterococcus faecium resistant a la vancomycine - Google Patents

Souches de bacteriophages utiles pour sauver des patients infectes par enterococcus faecium resistant a la vancomycine

Info

Publication number
EP1180937A4
EP1180937A4 EP00931911A EP00931911A EP1180937A4 EP 1180937 A4 EP1180937 A4 EP 1180937A4 EP 00931911 A EP00931911 A EP 00931911A EP 00931911 A EP00931911 A EP 00931911A EP 1180937 A4 EP1180937 A4 EP 1180937A4
Authority
EP
European Patent Office
Prior art keywords
enterococcus faecium
patients infected
resistant enterococcus
vancomycin resistant
strains useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00931911A
Other languages
German (de)
English (en)
Other versions
EP1180937A1 (fr
Inventor
Carl R Merril
Richard M Carlton
Sankar Adhya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exponential Biotherapies Inc
National Institutes of Health
Original Assignee
Exponential Biotherapies Inc
National Institutes of Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exponential Biotherapies Inc, National Institutes of Health filed Critical Exponential Biotherapies Inc
Publication of EP1180937A1 publication Critical patent/EP1180937A1/fr
Publication of EP1180937A4 publication Critical patent/EP1180937A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00931911A 1999-05-13 2000-05-12 Souches de bacteriophages utiles pour sauver des patients infectes par enterococcus faecium resistant a la vancomycine Withdrawn EP1180937A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13405599P 1999-05-13 1999-05-13
US134055P 1999-05-13
PCT/US2000/006718 WO2000069269A1 (fr) 1999-05-13 2000-05-12 Souches de bacteriophages utiles pour sauver des patients infectes par enterococcus faecium resistant a la vancomycine

Publications (2)

Publication Number Publication Date
EP1180937A1 EP1180937A1 (fr) 2002-02-27
EP1180937A4 true EP1180937A4 (fr) 2004-08-04

Family

ID=22461568

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00931911A Withdrawn EP1180937A4 (fr) 1999-05-13 2000-05-12 Souches de bacteriophages utiles pour sauver des patients infectes par enterococcus faecium resistant a la vancomycine

Country Status (5)

Country Link
EP (1) EP1180937A4 (fr)
JP (1) JP2002543816A (fr)
AU (1) AU4971900A (fr)
CA (1) CA2373486A1 (fr)
WO (1) WO2000069269A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1230206C (zh) 2000-01-11 2005-12-07 内立蒂克斯股份有限公司 作为生产生物复合材料的生物可降解基质的聚合物混合物
US6759229B2 (en) 2001-12-18 2004-07-06 President & Fellows Of Harvard College Toxin-phage bacteriocide antibiotic and uses thereof
GB0209680D0 (en) * 2002-04-27 2002-06-05 Univ Strathclyde Immobilisation and stabilisation of bacteriophage
WO2004052274A2 (fr) 2002-12-09 2004-06-24 Phage Biopharm Llc Production de compositions bacteriophages destinees a etre utilisees dans la therapie phagique
DE10342071B4 (de) * 2003-09-10 2006-01-19 Fleischmann, Wilhelm, Dr.med. Vorrichtung und Verfahren zur Applikation von Wïrkstoffen an eine Wundoberfläche
US8178087B2 (en) 2006-04-04 2012-05-15 Centre National de la Recherche Scientifique —CNRS Process of production of bacteriophage compositions and methods in phage therapy field
KR100958139B1 (ko) * 2008-03-31 2010-05-18 주식회사 인트론바이오테크놀로지 엔테로코쿠스 패칼리스 특이적 사멸능을 갖는 신규한박테리오파지
PL215522B1 (pl) 2008-09-29 2013-12-31 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Enterococcus
KR100988771B1 (ko) * 2008-09-29 2010-10-20 주식회사 인트론바이오테크놀로지 엔테로코쿠스 및 스트렙토코쿠스 특이적 사멸능을 갖는 신규한 리신 단백질
ES2761835T3 (es) * 2009-02-06 2020-05-21 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fagos antibacterianos, péptidos de fagos y métodos de uso de los mismos
US20190307818A1 (en) 2016-04-08 2019-10-10 The Trustees Of Princeton University Novel antimicrobial compositions and methods of use
KR101822812B1 (ko) * 2017-02-22 2018-01-29 주식회사 인트론바이오테크놀로지 신규한 엔테로코쿠스 패슘 박테리오파지 Ent-FAP-4 및 이의 엔테로코쿠스 패슘 증식 억제 용도
KR101957266B1 (ko) * 2017-02-22 2019-03-13 주식회사 인트론바이오테크놀로지 엔테로코쿠스 패슘에 대하여 용균력을 가지는 신규한 항균단백질 efal-2
GB201712733D0 (en) 2017-08-08 2017-09-20 Snipr Tech Ltd Methods & cells
KR102203679B1 (ko) * 2018-12-26 2021-01-15 주식회사 옵티팜 신규한 엔테로코커스 패시움 균 특이 박테리오파지 ef44 및 이를 포함하는 항균 조성물
GB201901099D0 (en) 2019-01-27 2019-03-13 Snipr Biome Aps Methods, uses and compositions
EP4355345A1 (fr) * 2021-06-15 2024-04-24 Ferring B.V. Bactériophages contre les entérocoques résistants à la vancomycine
GB202209518D0 (en) 2022-06-29 2022-08-10 Snipr Biome Aps Treating & preventing E coli infections
JP2025525414A (ja) 2022-06-29 2025-08-05 エスエヌアイピーアール・バイオーム・アーペーエス Ｅ ｃｏｌｉ細胞の標的化

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766892A (en) * 1994-04-05 1998-06-16 Exponential Biotherapies, Inc. Antibacterial therapy with bacteriophage genotypically modified to delay inactivation by the host defense system together with an antibiotic

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766892A (en) * 1994-04-05 1998-06-16 Exponential Biotherapies, Inc. Antibacterial therapy with bacteriophage genotypically modified to delay inactivation by the host defense system together with an antibiotic

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALISKY J ET AL: "BACTERIOPHAGE SHOW PROMISE AS ANTIMICROBIAL AGENTS", JOURNAL OF INFECTION, ACADEMIC PRESS, LONDON, GB, vol. 36, 1998, pages 5 - 15, XP000993238, ISSN: 0163-4453 *
See also references of WO0069269A1 *

Also Published As

Publication number Publication date
JP2002543816A (ja) 2002-12-24
EP1180937A1 (fr) 2002-02-27
AU4971900A (en) 2000-12-05
WO2000069269A9 (fr) 2002-02-21
CA2373486A1 (fr) 2000-11-23
WO2000069269A1 (fr) 2000-11-23

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