EP1207941A1 - Einrichtung zur stereotaktischen radiotherapie - Google Patents
Einrichtung zur stereotaktischen radiotherapieInfo
- Publication number
- EP1207941A1 EP1207941A1 EP00948208A EP00948208A EP1207941A1 EP 1207941 A1 EP1207941 A1 EP 1207941A1 EP 00948208 A EP00948208 A EP 00948208A EP 00948208 A EP00948208 A EP 00948208A EP 1207941 A1 EP1207941 A1 EP 1207941A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- head
- axis
- radiogenic
- stereotaxic
- integral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000001959 radiotherapy Methods 0.000 title claims abstract description 24
- 238000011282 treatment Methods 0.000 claims abstract description 42
- 230000003902 lesion Effects 0.000 claims abstract description 24
- 230000005855 radiation Effects 0.000 claims abstract description 17
- 208000029028 brain injury Diseases 0.000 claims abstract description 3
- 238000006073 displacement reaction Methods 0.000 claims description 8
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- 238000007906 compression Methods 0.000 claims description 6
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- 238000000034 method Methods 0.000 description 8
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- 206010028980 Neoplasm Diseases 0.000 description 2
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- 208000022211 Arteriovenous Malformations Diseases 0.000 description 1
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 206010048409 Brain malformation Diseases 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010051290 Central nervous system lesion Diseases 0.000 description 1
- GUTLYIVDDKVIGB-OUBTZVSYSA-N Cobalt-60 Chemical compound [60Co] GUTLYIVDDKVIGB-OUBTZVSYSA-N 0.000 description 1
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- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/01—Devices for producing movement of radiation source during therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
- A61B2090/101—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis for stereotaxic radiosurgery
Definitions
- the invention finds applications particularly in the field of fractionated stereotaxic radiotherapy and radiosurgery. Without being limiting, the present invention applies in particular to the treatment of brain tumors and malformations, which will be designated below by the term lesions, this term being applied generically to everything which can be treated by radiotherapy or radiosurgery.
- radiosurgery and radiotherapy under stereotaxic conditions proceed in two stages: identification of the three-dimensional coordinates of the lesions to be treated in a reference space defined by the stereotaxis frame.
- the process for irradiating brain damage using the radioactive sources of Co60 is well known.
- the processing apparatus has in particular been described in US-A-4780898. It includes a roughly hemispherical source-collimator assembly and a mobile patient support table equipped with a device intended to cooperate with the patient's head.
- the source-collimator assembly comprises a large number of external sources of gamma rays associated respectively with channels which are all oriented towards the same focal point. While at the focal point the dose received from all of the mini-beams is sufficient to destroy the lesion, the intensity of each mini-beam taken separately is low so as not to damage the healthy tissue it crosses.
- Linear accelerators of conventional radiotherapy have the disadvantage of having a single axis of rotation of the support of the radiogenic head.
- Several solutions have been proposed to remedy this drawback. They can be grouped into two classes depending on the patient's position.
- Betti et al. Propose a system for positioning and tilting the frame (on two rigid columns) and a special chair, capable of turning around a horizontal axis. zontal passing through the isocentre (treatment chair), so that the patient 's body accompanies the rotational movement of the head.
- the target is placed at the isocenter of rotation of the irradiation beam, through which also passes the axis of rotation (transverse) of the stereotaxic system.
- a combination of several arcs (each with an angular position of the head) gives a set of non-coplanar concentric arcs.
- the patient goes from one arc therapy to the next in the supine position.
- the isocentric rotation of the treatment table around the vertical axis allows moving from one arctherapy to the next.
- the patient's head is fixed on a support which is linked to the treatment table or on an isocentric head support on a console independent of the table.
- the combination of the isocentric rotation of the linear accelerator arm with different angular positions of the treatment table ensures multiple arc irradiation.
- the treatment table being guided remotely, a simultaneous and continuous movement of the accelerator arm and the treatment table makes possible the so-called dynamic irradiation.
- radioactive sources conventional linear accelerator
- this framework constitutes an orthonormal reference frame making it possible to determine the coordinates of any point on the patient's head.
- the identification of the internal areas that are involved is done in this repository using, for example, a scanner, an MRI, an angiography or any other method of spatial location of these areas.
- the stereotaxic framework therefore constitutes a benchmark outside the patient's head in which it is possible to locate one or more brain areas in order to ensure their treatment by radiotherapy. Numerous devices are known which make it possible to associate a frame of reference with the head of a patient and to identify in this frame of reference the internal zones which are involved by means, for example, of a radio tomography.
- the stereotaxis frame also serves to reproduce the position of the patient's head identically during the treatment. It constitutes on the patient's head the means of its precise positioning in the repository of the radiotherapeutic treatment apparatus.
- This repository is not the same as the snapshot repository, the treatment machine being completely dissociated from the machine used for locating and spatially locating the area to be treated.
- the stereotaxic frame thus constitutes the mechanical support for the precise positioning of the patient's head under the radiotherapy device.
- radiotherapy devices have already been proposed in the past in which a radiation source of low intensity, such as an X-ray bulb could move in two axes.
- a radiation source of low intensity such as an X-ray bulb could move in two axes.
- Such devices are described in particular in FR 1071 714, as well as in FR 1 093 061.
- these devices comprise a pivot axis always fixed and a second axis cutting the axis of pivoting and defining a second circular trajectory and whose angle relative to this pivoting axis can vary more or less from a right angle, so that by rotating the carrier head of the radiation source, the beam from this source can describe two cones opposite by their vertices, on either side of the position where the axes intersect at 90 °.
- the fixed pivot axis is therefore not kinematically integral with the guide means defining the second circular path. Both are independent of each other.
- the pivoting means carry not only the radiogenic head, but also the means making it possible to guide this head along the second circular path, so that these pivoting means are urged by a large overhang. If such a solution poses obvious problems of wear and precision in the positioning of the beam, it should be noted that these devices are designed for small sources of low intensity radiation weighing a few kg. Such solutions would not in all cases be applicable for precisely guiding sources such as linear accelerators weighing several hundred kg.
- the subject of the present invention is a stereotaxic radiotherapy device as defined by claim 1.
- the device according to the present invention always works in the same coordinate system with respect to the same isocentre thus making it possible to successively carry out the radiiotomographic localization of the area to be treat and then treat the lesion thus localized, using gamma rays.
- Table 2 includes for this purpose a support and universal adapters 10, of which is shown in Figures 3 and 10, for positioning the various stereotaxic frames 11 existing; which makes it possible at any time to fix a stereotaxic frame 11 for locating in an external coordinate system and being able to perform simulations.
- Each stereotaxic frame 11 can be provided with a specific universal adapter 10 left permanently, which allows rapid repositioning.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00948208A EP1207941A1 (de) | 1999-08-11 | 2000-08-08 | Einrichtung zur stereotaktischen radiotherapie |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99420178A EP1075855A1 (de) | 1999-08-11 | 1999-08-11 | Einrichtung zur stereotaktischen Radiotherapie |
| EP99420178 | 1999-08-11 | ||
| EP00948208A EP1207941A1 (de) | 1999-08-11 | 2000-08-08 | Einrichtung zur stereotaktischen radiotherapie |
| PCT/IB2000/001109 WO2001012262A1 (fr) | 1999-08-11 | 2000-08-08 | Dispositif de radiotherapie stereotaxique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1207941A1 true EP1207941A1 (de) | 2002-05-29 |
Family
ID=8242291
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99420178A Withdrawn EP1075855A1 (de) | 1999-08-11 | 1999-08-11 | Einrichtung zur stereotaktischen Radiotherapie |
| EP00948208A Withdrawn EP1207941A1 (de) | 1999-08-11 | 2000-08-08 | Einrichtung zur stereotaktischen radiotherapie |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99420178A Withdrawn EP1075855A1 (de) | 1999-08-11 | 1999-08-11 | Einrichtung zur stereotaktischen Radiotherapie |
Country Status (3)
| Country | Link |
|---|---|
| EP (2) | EP1075855A1 (de) |
| AU (1) | AU6176900A (de) |
| WO (1) | WO2001012262A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6653595B2 (ja) * | 2016-03-04 | 2020-02-26 | 株式会社日立製作所 | 粒子線治療システム |
| US11058892B2 (en) | 2017-05-05 | 2021-07-13 | Zap Surgical Systems, Inc. | Revolving radiation collimator |
| CN108401421B (zh) | 2017-09-06 | 2022-12-20 | 睿谱外科系统股份有限公司 | 自屏蔽的集成控制放射外科系统 |
| CN109847198B (zh) * | 2018-12-29 | 2024-07-16 | 佛山瑞加图医疗科技有限公司 | 一种加速器调整装置 |
| US11684446B2 (en) | 2019-02-27 | 2023-06-27 | Zap Surgical Systems, Inc. | Device for radiosurgical treatment of uterine fibroids |
| EP4284501A4 (de) | 2021-02-01 | 2025-01-01 | Zap Surgical Systems, Inc. | Inverse planungsvorrichtung und verfahren zur strahlenbehandlung |
| CN118846401A (zh) * | 2023-04-28 | 2024-10-29 | 中硼(厦门)医疗器械有限公司 | 参考物定位装置及其定位方法、放射线照射系统 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1033844B (de) * | 1951-09-04 | 1958-07-10 | Ialicenciaia Talalmanyokat Ert | Roentgenapparat fuer Bewegungsbestrahlung |
| US2781454A (en) * | 1952-12-04 | 1957-02-12 | Ca Atomic Energy Ltd | Rotational therapy unit |
| SE453156B (sv) | 1986-04-30 | 1988-01-18 | Elekta Instr Sa | Stralkniv innefattande ett stort antal inom ett stralskydd anordnade stralkellor |
| US4741015A (en) * | 1986-12-05 | 1988-04-26 | B. C. Medical Compagnie Limitee | Universal X-ray unit |
| US5107839A (en) * | 1990-05-04 | 1992-04-28 | Pavel V. Houdek | Computer controlled stereotaxic radiotherapy system and method |
| JP3468372B2 (ja) * | 1992-09-07 | 2003-11-17 | 株式会社日立メディコ | 定位的放射線治療装置 |
| FR2748650B1 (fr) | 1996-05-20 | 1998-08-07 | Betti Osvaldo Oscar | Unite de radiochirurgie |
-
1999
- 1999-08-11 EP EP99420178A patent/EP1075855A1/de not_active Withdrawn
-
2000
- 2000-08-08 WO PCT/IB2000/001109 patent/WO2001012262A1/fr not_active Ceased
- 2000-08-08 AU AU61769/00A patent/AU6176900A/en not_active Abandoned
- 2000-08-08 EP EP00948208A patent/EP1207941A1/de not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| See references of WO0112262A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001012262A1 (fr) | 2001-02-22 |
| AU6176900A (en) | 2001-03-13 |
| EP1075855A1 (de) | 2001-02-14 |
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Legal Events
| Date | Code | Title | Description |
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| 17P | Request for examination filed |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 18D | Application deemed to be withdrawn |
Effective date: 20030301 |