EP1235523B1 - Plaque vissee resorbable - Google Patents

Plaque vissee resorbable Download PDF

Info

Publication number
EP1235523B1
EP1235523B1 EP99974247A EP99974247A EP1235523B1 EP 1235523 B1 EP1235523 B1 EP 1235523B1 EP 99974247 A EP99974247 A EP 99974247A EP 99974247 A EP99974247 A EP 99974247A EP 1235523 B1 EP1235523 B1 EP 1235523B1
Authority
EP
European Patent Office
Prior art keywords
holes
bone plate
bone
plate according
plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP99974247A
Other languages
German (de)
English (en)
Other versions
EP1235523A1 (fr
Inventor
Raymond Curtis
Markus Hehli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthes GmbH
Original Assignee
Synthes AG Chur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes AG Chur filed Critical Synthes AG Chur
Publication of EP1235523A1 publication Critical patent/EP1235523A1/fr
Application granted granted Critical
Publication of EP1235523B1 publication Critical patent/EP1235523B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8052—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates immobilised relative to screws by interlocking form of the heads and plate holes, e.g. conical or threaded
    • A61B17/8057—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates immobilised relative to screws by interlocking form of the heads and plate holes, e.g. conical or threaded the interlocking form comprising a thread
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/0084—Material properties low friction

Definitions

  • This invention concerns a bone plate in accordance with the pre-characterising portion of Claim 1.
  • a bone plate is disclosed in EP-A- 0530585, which defines the preamble of claim 1.
  • Bone plates made of titanium have shown that this material has such a bio-compatibility that soft-tissue is adhering thereto which can be in certain situations an undesirable property for bone plates.
  • bone plates made of bioresorbable materials usually have insufficient mechanical properties (e.g. stiffness).
  • the invention as claimed aims at overcoming the problems of adherence of soft-tissue and to optimize shape and function of an resorbable plate given the limitations of the properties of these materials.
  • the present invention provides a bone plate as defined in Claim 1.
  • Resorbable materials to be used for the device according to the invention can be resorbable polymers like highly purified polyhydroxyacids, polysaccharides, polyamines, polyaminoacids, polyorthoesters, polyanhydrides, polyamidoesters, polydioxanone, polyesteramides, copolyoxalates, polycarbonates or poly-(glutamic-co-leucine).
  • polylactides are used or their combinations with polyhydroxybutyrates or polyhydroxyvalerates and/or resorbable glasses.
  • polyhydroxyacids comprise polycaprolactone, poly(L-lactide), poly(DL-lactide), polyglycolide, poly-(DL-lactide-co-glycolide), poly(DL-lactide-co-caprolactone).
  • the lower surface of the bone plate has a radius of curvature R which is smaller than 9 mm.
  • the axis of the hollow cylinder corresponding to the curved plate is running parallel to the central longitudinal axis of the plate.
  • the ratio F/d of the total area F of the upper surface (including the surface area of the through holes) to the thickness d of the plate is in the range of 210 to 240 mm.
  • the ratio F/f of the total area F of the upper surface (including the surface area of the through holes) to the true surface f of the upper surface (excluding the surface area of the through holes) is in the range of 1,10 - 1,25.
  • the width of the free ends of the longitudinal plate is narrowing to value b being preferably smaller than 0,15 B.
  • the upper surface of the bone plate has preferably a roughness of 0,5 ⁇ m to 5,0 ⁇ m, typically of 0,6 ⁇ m to 2,5 ⁇ m. in order to avoid the adherence of soft tissue after implantation. In any case it is preferred that the upper surface is smoother than the lower surface.
  • the bone plate is provided with a torsion around its central longitudinal axis which allows application to the required bone profile.
  • the degree of torsion of the bone plate is preferably between ⁇ 1° to ⁇ 20° over the total length.
  • the length 1 of the central part of the longitudinal plate corresponds preferably to 73 - 82 % of the total length L of the plate.
  • conical through holes may be provided with a thread.
  • through holes it is also possible to use through holes with a smooth inner surface.
  • the through holes have preferably a cone angle of 15° to 25°, typically of 18° to 22°.
  • the bone plate is provided preferably with n ⁇ 4 holes (more preferably with n ⁇ 6 holes), whereby the two most centrally located holes have preferably a distance which is at least 150 %, preferably 180 % of the distance x between the other through holes.
  • Figure 1 shows a bone plate of longitudinal shape having an upper curved surface 1, a curved lower surface 2 for contacting a long bone, e.g. a metacarpal bone, six conical through holes 3 connecting the upper surface 1 with the lower surface 2 for receiving bone screws and a central longitudinal axis 4.
  • a long bone e.g. a metacarpal bone
  • six conical through holes 3 connecting the upper surface 1 with the lower surface 2 for receiving bone screws and a central longitudinal axis 4.
  • the through holes 3 have a cone angle of 20° and a minimum diameter D of 2,8 mm located at the lower side 2.
  • the lower surface 2 has a radius of curvature R of 7 mm.
  • the plate consists of polylactide copolymer with an enhanced degradation rate.
  • the ratio F/d of the total area F of the upper surface 1 (including the surface area of the through holes 3) to the thickness d of the plate has the value of 223 mm.
  • the ratio F/f of the total area F of the upper surface 1 including the surface area of the through holes 3 to the true surface f of the upper surface 1 excluding the surface area of the through holes 3 has the value of 1,17.
  • the central part of the longitudinal plate (over the length 1 in Fig. 1) has a constant width B whereas the width of the free ends of the longitudinal plate is narrowing gradually to value O in the form of a hemi-circle.
  • the length 1 of the central part of the longitudinal plate corresponds to 77 % of the total length L of the plate.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)

Claims (13)

  1. Plaquette pour les os de forme longitudinale comportant une face supérieure (1), une face inférieure courbée (2) destinée à entrer en contact avec l'os, une pluralité de perçages traversants coniques (3) reliant la face supérieure (1) à la face inférieure (2) pour recevoir des vis pour les os, un axe central longitudinal (4) et constitué d'un matériau résorbable,
    caractérisée en ce que
    A) la face inférieure courbée (2) a un rayon de courbure R inférieur à 10 mm,
    B) le ratio F/d de la surface totale F de la face supérieure (1) comprenant la surfaces des perçages traversants (3) à l'épaisseur d de la plaquette est compris entre 190 et 270 mm, et
    C) la partie centrale de la plaquette longitudinale a une largeur B généralement constante, la largeur des extrémités dégagées de cette plaquette longitudinale se rétrécissant pour atteindre une valeur b jusqu'à 0,3 B.
  2. Plaquette pour les os selon la revendication 1, caractérisée en ce que le rayon de la courbure R est inférieur à 9 mm.
  3. Plaquette pour les os selon la revendication 1 ou 2, caractérisée en ce que le ratio F/d est compris entre 210 et 240 mm.
  4. Plaquette pour les os selon une des revendications 1 à 3, caractérisée en ce que le ratio F/f de la surface totale F de la face supérieure (1) comprenant la surface des perçages traversants (3) à la surface exacte f de la face supérieure (1), qui ne comprend pas la surface des trous traversants (3), est compris entre 1,10 à 1,25.
  5. Plaquette pour les os selon une des revendications 1 à 4, caractérisée en ce que la largeur des extrémités dégagées de la plaquette longitudinale se rétrécit pour atteindre une valeur b jusqu'à 0,15 B.
  6. Plaquette pour les os selon une des revendications 1 à 5, caractérisée en ce que la face supérieure (1) a une rugosité de 0,5 à 5,0 µm, de préférence de 0,5 à 2,5 µm.
  7. Plaquette pour les os selon une des revendications 1 à 6, caractérisée en ce que la face supérieure (1) est plus lisse que la face inférieure (2).
  8. Plaquette pour les os selon une des revendications 1 à 6, caractérisée en ce que la plaquette est pourvue d'une torsion autour de son axe central longitudinal (4).
  9. Plaquette pour les os selon une des revendications 1 à 8, caractérisée en ce que la longueur I de la partie centrale de la plaquette longitudinale est égale à 73-82 % de la longueur totale L de la plaquette.
  10. Plaquette pour les os selon une des revendications 1 à 9, caractérisée en ce que les perçages coniques traversants (3) sont pourvus d'un filetage.
  11. Plaquette pour les os selon une des revendications 1 à 10, caractérisée en ce que les perçages coniques traversants (3) ont une surface intérieure lisse.
  12. Plaquette pour les os selon une des revendications 1 à 11, caractérisée en ce qu'elle est pourvue d'un nombre n = 4 perçages (3), de préférence de n = 6 perçages (3) et que les deux perçages (3) situés le plus au centre ont une distance qui est au moins égale à 102 %, de préférence 150 à 180 % de la distance x entre les autres trous (3).
  13. Plaquette pour les os selon une des revendications 1 à 12, caractérisée en ce que les trous traversants (3) ont un angle de cône de 15° à 25°, de préférence de 18° à 22°.
EP99974247A 1999-12-06 1999-12-06 Plaque vissee resorbable Expired - Lifetime EP1235523B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH1999/000582 WO2001041663A1 (fr) 1999-12-06 1999-12-06 Plaque vissee resorbable

Publications (2)

Publication Number Publication Date
EP1235523A1 EP1235523A1 (fr) 2002-09-04
EP1235523B1 true EP1235523B1 (fr) 2004-09-01

Family

ID=4551743

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99974247A Expired - Lifetime EP1235523B1 (fr) 1999-12-06 1999-12-06 Plaque vissee resorbable

Country Status (10)

Country Link
US (1) US20030004515A1 (fr)
EP (1) EP1235523B1 (fr)
JP (1) JP2003515426A (fr)
AT (1) ATE274857T1 (fr)
AU (1) AU770059B2 (fr)
CA (1) CA2393206A1 (fr)
DE (1) DE69919911T2 (fr)
ES (1) ES2229826T3 (fr)
HK (1) HK1048748B (fr)
WO (1) WO2001041663A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2187195T3 (es) * 1998-09-11 2003-05-16 Gerhard Dr Schmidmaier Implantes biologicamente activos.
US20050038435A1 (en) 2000-08-22 2005-02-17 J. Dean Cole Intramerdullary canal diameter reducer background of the invention
US7811312B2 (en) * 2002-12-04 2010-10-12 Morphographics, Lc Bone alignment implant and method of use
US8551145B2 (en) 2005-12-19 2013-10-08 Mayo Foundation For Medical Education And Research Anterior adherent thoracolumbar spine plate
US8057520B2 (en) * 2006-07-18 2011-11-15 Orthohelix Surgical Designs, Inc. Calcaneal plate
US20080312698A1 (en) * 2007-06-14 2008-12-18 Bergeron Brian J Device and system for stabilizing movement between bony tissue and method for implanting
US20090082816A1 (en) * 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
US20100094352A1 (en) * 2008-10-10 2010-04-15 Andrew Iott Bone screw
JP6096190B2 (ja) 2011-08-16 2017-03-15 シンセス・ゲーエムベーハーＳｙｎｔｈｅｓ ＧｍｂＨ 熱可塑性多層物品
CA2854667C (fr) 2011-11-07 2021-03-30 Thomas Imwinkelried Electrolyte faible pour revetements plasmaelectrolytiques biocompatibles sur implant en magnesium
EP3308736B1 (fr) * 2015-06-09 2022-04-06 She, Chengxin Plaque osseuse de fixation

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3695259A (en) * 1970-11-10 1972-10-03 Clyde E Yost Bone plate
US4776330A (en) * 1986-06-23 1988-10-11 Pfizer Hospital Products Group, Inc. Modular femoral fixation system
US4905680A (en) * 1986-10-27 1990-03-06 Johnson & Johnson Orthopaedics, Inc. Absorbable bone plate
US4966599A (en) * 1987-04-07 1990-10-30 Pollock Richard A Anatomical precontoured plating, instruments and methods
US5151103A (en) * 1987-11-03 1992-09-29 Synthes (U.S.A.) Point contact bone compression plate
JP3148932B2 (ja) * 1991-06-28 2001-03-26 タキロン株式会社 骨折部の内固定材用生体内分解吸収性プレート
US5275601A (en) * 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
FR2693899B1 (fr) * 1992-07-24 1994-09-23 Laboureau Jacques Agrafe-plaque d'ostéosynthèse.
US6491723B1 (en) * 1996-02-27 2002-12-10 Implant Innovations, Inc. Implant surface preparation method
ES2158127T3 (es) * 1995-09-06 2001-09-01 Synthes Ag Lamina osea.
US6033582A (en) * 1996-01-22 2000-03-07 Etex Corporation Surface modification of medical implants
GB9801987D0 (en) * 1998-01-31 1998-03-25 Depuy Int Ltd A fixation device for a bone fracture
US7052499B2 (en) * 1998-02-18 2006-05-30 Walter Lorenz Surgical, Inc. Method and apparatus for bone fracture fixation
ES1039613Y (es) * 1998-02-24 1999-06-01 Mecanismos Aux Ind Portamodulos de dos modulos perfeccionado.
US6221075B1 (en) * 1998-03-06 2001-04-24 Bionx Implants Oy Bioabsorbable, deformable fixation plate
US5861452A (en) * 1998-03-20 1999-01-19 E. I. Du Pont De Nemours And Company Scratch and scuff resistant polymer
DE19951760B4 (de) * 1999-10-27 2005-06-09 Sepitec Foundation Implantat für Osteosynthesen

Also Published As

Publication number Publication date
DE69919911D1 (de) 2004-10-07
JP2003515426A (ja) 2003-05-07
HK1048748A1 (en) 2003-04-17
AU770059B2 (en) 2004-02-12
ES2229826T3 (es) 2005-04-16
AU1371000A (en) 2001-06-18
ATE274857T1 (de) 2004-09-15
US20030004515A1 (en) 2003-01-02
DE69919911T2 (de) 2005-09-15
CA2393206A1 (fr) 2001-06-14
EP1235523A1 (fr) 2002-09-04
HK1048748B (en) 2004-12-31
WO2001041663A1 (fr) 2001-06-14

Similar Documents

Publication Publication Date Title
US6755832B2 (en) Bone plate implant
CA2076501C (fr) Vis et plaques resorbables auto-verrouillables pour la fixation interne des fractures osseuses et la liaison tendon-os
HK1048748A1 (en) Resorbable bone plate
US11317957B2 (en) Fiber reinforced biocomposite threaded implants
JP3766104B2 (ja) 骨外科用装置
US5584836A (en) Cannulated medical suture anchor
US5236431A (en) Resorbable fixation device with controlled stiffness for treating bodily material in vivo and introducer therefor
US8721694B2 (en) Bone screw washer
CA2736587C (fr) Implant intramedullaire resorbable entre deux os ou deux fragments osseux
CN114010297A (zh) 远侧桡骨板
HK1048750A1 (en) Bone plate
AU2005282396A1 (en) Minimal thickness bone plate locking mechanism
EP0637944A1 (fr) Vis a os resorbable et son outil d'insertion
ZA200202401B (en) Resorbable bone plate.
EP3096697B1 (fr) Broche allongée pour l'application d'un fixateur externe
JPH09253089A (ja) 骨固定用ネジ
TH46901A (th) แผ่นยึดกระดูกที่ดูดซับใหม่ได้

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020325

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040901

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040901

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040901

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20040901

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: DR. LUSUARDI AG

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REF Corresponds to:

Ref document number: 69919911

Country of ref document: DE

Date of ref document: 20041007

Kind code of ref document: P

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20041201

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20041201

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20041201

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20041206

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20041206

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20041231

REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1048748

Country of ref document: HK

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2229826

Country of ref document: ES

Kind code of ref document: T3

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20050602

EN Fr: translation not filed
REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20051104

Year of fee payment: 7

Ref country code: AT

Payment date: 20051104

Year of fee payment: 7

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20051109

Year of fee payment: 7

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20051201

Year of fee payment: 7

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20051216

Year of fee payment: 7

REG Reference to a national code

Ref country code: CH

Ref legal event code: PUE

Owner name: SYNTHES GMBH

Free format text: SYNTHES AG CHUR#GRABENSTRASSE 15#7002 CHUR (CH) -TRANSFER TO- SYNTHES GMBH#EIMATTSTRASSE 3#4436 OBERDORF (CH)

REG Reference to a national code

Ref country code: GB

Ref legal event code: 732E

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20061123

Year of fee payment: 8

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20061231

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20061231

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20061231

Year of fee payment: 8

NLS Nl: assignments of ep-patents

Owner name: SYNTHES GMBH

Effective date: 20061030

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20070701

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20070703

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

NLV4 Nl: lapsed or anulled due to non-payment of the annual fee

Effective date: 20070701

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20061206

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20050201

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20061207

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20061207

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20071206

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20071206

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20071206