EP1331265A3 - Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen - Google Patents

Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen Download PDF

Info

Publication number
EP1331265A3
EP1331265A3 EP03008169A EP03008169A EP1331265A3 EP 1331265 A3 EP1331265 A3 EP 1331265A3 EP 03008169 A EP03008169 A EP 03008169A EP 03008169 A EP03008169 A EP 03008169A EP 1331265 A3 EP1331265 A3 EP 1331265A3
Authority
EP
European Patent Office
Prior art keywords
protein tyrosine
tyrosine phosphatases
disclosed
dep
enhanced protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03008169A
Other languages
English (en)
French (fr)
Other versions
EP1331265A2 (de
Inventor
Nicholas K. Tonks
Arnie Ostman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cold Spring Harbor Laboratory
Original Assignee
Cold Spring Harbor Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22895876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1331265(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cold Spring Harbor Laboratory filed Critical Cold Spring Harbor Laboratory
Publication of EP1331265A2 publication Critical patent/EP1331265A2/de
Publication of EP1331265A3 publication Critical patent/EP1331265A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP03008169A 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen Withdrawn EP1331265A3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23794094A 1994-05-03 1994-05-03
US237940 1994-05-03
EP95918943A EP0708831B2 (de) 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP95918943A Division EP0708831B2 (de) 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen

Publications (2)

Publication Number Publication Date
EP1331265A2 EP1331265A2 (de) 2003-07-30
EP1331265A3 true EP1331265A3 (de) 2003-08-06

Family

ID=22895876

Family Applications (2)

Application Number Title Priority Date Filing Date
EP03008169A Withdrawn EP1331265A3 (de) 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen
EP95918943A Expired - Lifetime EP0708831B2 (de) 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP95918943A Expired - Lifetime EP0708831B2 (de) 1994-05-03 1995-05-03 Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen

Country Status (7)

Country Link
US (4) US6114140A (de)
EP (2) EP1331265A3 (de)
JP (2) JPH09500794A (de)
AT (1) ATE236983T1 (de)
DE (1) DE69530261T3 (de)
DK (1) DK0708831T4 (de)
WO (1) WO1995030008A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69530261T3 (de) * 1994-05-03 2008-07-03 Cold Spring Harbor Laboratory Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen
US7176289B1 (en) * 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6248327B1 (en) * 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
MXPA02008462A (es) * 2000-03-01 2004-05-14 Univ Vanderbilt Modulacion de la actividad de receptor de superficie celular endotelial en la regulacion de angiogenesis.
AU2003298761A1 (en) * 2002-11-26 2004-06-18 Cold Spring Harbor Laboratory Dep-1 receptor protein tyrosine phosphatase interacting proteins and related methods
BRPI0510079A (pt) * 2004-04-23 2007-10-16 Amgen Inc anticorpo isolado ou região de ligação de antìgeno do mesmo, célula de hibridoma, célula de transfectoma, anticorpo monoclonal ou região de ligação de antìgeno do mesmo, animal não humano transgênico, método para produzir um anticorpo ou região de ligação de antìgeno do mesmo, composição farmacêutica, uso do anticorpo ou região de ligação de antìgeno, polipeptìdeo isolado, imunoensaio, e, método para identificar um composto
WO2018222901A1 (en) 2017-05-31 2018-12-06 Elstar Therapeutics, Inc. Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
AU2024251286A1 (en) 2023-04-07 2025-10-30 Infinitopes Limited Methods and compositions for cancer treatment using recombinant polypeptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5441880A (en) * 1991-11-18 1995-08-15 Cold Spring Harbor Laboratory Human cdc25 genes, encoded products and uses thereof
GB9216328D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Isolation and cloning of a protein with tyrosine-phosphatase activity
US5512434A (en) * 1992-12-14 1996-04-30 The United States Of America As Represented By The Department Of Health And Human Services Expression cloning of a human phosphatase
DE69530261T3 (de) * 1994-05-03 2008-07-03 Cold Spring Harbor Laboratory Durch Zelldichte stimulierte Protein-Tyrosin-Phosphatasen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HONDA HIROAKI ET AL: "Molecular cloning, characterization, of chromosomal localization of a novel protein-tyrosine phosphatase, HPTP-eta.", BLOOD, vol. 84, no. 12, 15 December 1994 (1994-12-15), pages 4186 - 4194, XP002243341, ISSN: 0006-4971 *
MATOZAKI TAKASHI ET AL: "Molecular cloning of a human transmembrane-type protein tyrosine phosphatase and its expression in gastrointestinal cancers.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 3, 1994, pages 2075 - 2081, XP002243339, ISSN: 0021-9258 *
OSTMAN ARNE ET AL: "Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 91, no. 21, 1994, 1994, pages 9680 - 9684, XP002243340, ISSN: 0027-8424 *
PALLEN C J ET AL: "ELEVATION OF MEMBRANE TYROSINE PHOSPHATASE ACTIVITY IN DENSITY-DEPENDENT GROWTH-ARRESTED FIBROBLASTS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 88, no. 16, 1991, 1991, pages 6996 - 7000, XP002243338, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
DK0708831T4 (da) 2008-04-14
DE69530261D1 (de) 2003-05-15
EP0708831A1 (de) 1996-05-01
JPH09500794A (ja) 1997-01-28
DE69530261T3 (de) 2008-07-03
EP1331265A2 (de) 2003-07-30
US7195762B2 (en) 2007-03-27
US20030148491A1 (en) 2003-08-07
ATE236983T1 (de) 2003-04-15
WO1995030008A1 (en) 1995-11-09
EP0708831B2 (de) 2007-12-05
DK0708831T3 (da) 2003-08-04
US6552169B1 (en) 2003-04-22
US6114140A (en) 2000-09-05
DE69530261T2 (de) 2004-01-22
US20070190581A1 (en) 2007-08-16
JP2007312793A (ja) 2007-12-06
EP0708831B1 (de) 2003-04-09

Similar Documents

Publication Publication Date Title
EP2258722A3 (de) Antikörper gegen Fibroblasten Wachstumsfaktor-ähnliche Polypeptide
IL132067A0 (en) Apo-2 receptor
AU4327797A (en) Long wavelength engineered fluorescent proteins
AU1750297A (en) Humanized green fluorescent protein genes and methods
HU9600449D0 (en) Protocadherin proteins and their uses
WO1998021343A8 (en) Genes encoding telomerase proteins
NZ510356A (en) Molecules designated LDCAM
AU7155296A (en) Interleukin-19
WO2000015659A3 (en) Stomach polypeptide zsig28
DK0708831T4 (da) Celledensitetsforstærkede proteintyrosinphosphataser
CA2336261A1 (en) Cyclin e2 genes and proteins
WO1996031603A3 (en) Methods and compositions for regulating fadd
ZA978503B (en) Vertebrate smoothened proteins
EP0897011A3 (de) Arginin Deiminase
EP0643728A4 (de) Dem interzellulär-adhäsions-molekül (icam) ähnliche proteine.
AU5727099A (en) A 2,6-beta-d-fructan hydrolase enzyme and processes for using the enzyme
AU2001238064A1 (en) 18477, a human protein kinase and uses therefor
AU1183200A (en) Novel gene encoding brain-specific membrane protein
CA2166479A1 (en) Density enhanced protein tyrosine phosphatases
EP0879879A3 (de) Polypeptid-Deformylase 1 (Def1)
WO2000077179A3 (en) Human poly(adp-ribose) polymerase 2 materials and methods
WO2000024771A3 (en) Nucleic acids encoding osteoprotegerin-like proteins and methods of using same
EP0927763A3 (de) Neues aroA
WO2000007545A3 (en) Apoptosis proteins
EP0849362A3 (de) Streptococcus Proteine der spoT/relA Familie (spo/rel)

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AC Divisional application: reference to earlier application

Ref document number: 0708831

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

AK Designated contracting states

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17P Request for examination filed

Effective date: 20040206

AKX Designation fees paid

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20040823

17Q First examination report despatched

Effective date: 20050322

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070329