EP1349571A4 - Rotavirus-enterotoxin nsp4 und verfahren zu seiner verwendung - Google Patents

Rotavirus-enterotoxin nsp4 und verfahren zu seiner verwendung

Info

Publication number
EP1349571A4
EP1349571A4 EP01992588A EP01992588A EP1349571A4 EP 1349571 A4 EP1349571 A4 EP 1349571A4 EP 01992588 A EP01992588 A EP 01992588A EP 01992588 A EP01992588 A EP 01992588A EP 1349571 A4 EP1349571 A4 EP 1349571A4
Authority
EP
European Patent Office
Prior art keywords
nsp4
relates
rotavirus
rotavirus enterotoxin
enterotoxin nsp4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01992588A
Other languages
English (en)
French (fr)
Other versions
EP1349571A2 (de
Inventor
Mary K Estes
Judith M Ball
Peng Tian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/705,621 external-priority patent/US6673355B1/en
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Publication of EP1349571A2 publication Critical patent/EP1349571A2/de
Publication of EP1349571A4 publication Critical patent/EP1349571A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP01992588A 2000-11-03 2001-11-02 Rotavirus-enterotoxin nsp4 und verfahren zu seiner verwendung Withdrawn EP1349571A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/705,621 US6673355B1 (en) 1995-06-14 2000-11-03 Rotavirus enterotoxin NSP4 and methods of using same
US705621 2000-11-03
PCT/US2001/045255 WO2002036172A2 (en) 2000-11-03 2001-11-02 Rotavirus enterotoxin nsp4 and methods of using same

Publications (2)

Publication Number Publication Date
EP1349571A2 EP1349571A2 (de) 2003-10-08
EP1349571A4 true EP1349571A4 (de) 2005-02-16

Family

ID=24834264

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01992588A Withdrawn EP1349571A4 (de) 2000-11-03 2001-11-02 Rotavirus-enterotoxin nsp4 und verfahren zu seiner verwendung

Country Status (4)

Country Link
EP (1) EP1349571A4 (de)
AU (1) AU2002220025A1 (de)
CA (1) CA2427809A1 (de)
WO (1) WO2002036172A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1576877A1 (de) * 2004-03-04 2005-09-21 Bioprotein Technologies Herstellung von rekombinante Proteine aus Rotaviren in der Milch von nicht-menschlische transgenische Tiere
CA2630220C (en) 2005-11-22 2020-10-13 Doris Coit Norovirus and sapovirus antigens
ES2632429T3 (es) * 2012-02-14 2017-09-13 Merial, Inc. Vacunas subunitarias de rotavirus y procedimientos para la fabricación y utilización de las mismas
EP2849779B1 (de) 2012-05-16 2021-01-06 Adelaide Research & Innovation Pty Ltd. Zellimpfstoff und verfahren zur auslösung einer immunreaktion bei einer person
CA2974438A1 (en) * 2015-01-23 2016-07-28 Medicago Inc. Rotavirus-like particle production in plants
CN108504718A (zh) * 2018-03-27 2018-09-07 东莞市第三人民医院 一种CaSR在RV、NSP4感染后的表达水平分析方法
CN117866858B (zh) * 2023-11-30 2024-06-21 吉林农业大学 一种表达猪轮状病毒抗原的重组植物乳杆菌及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007941A1 (en) * 1990-10-25 1992-05-14 University Of Saskatchewan Assembled viral particles and their use in a vaccine to rotaviral disease
WO2001027335A1 (en) * 1999-10-14 2001-04-19 Baylor College Of Medicine A novel adjuvant
WO2001066566A2 (fr) * 2000-03-07 2001-09-13 Institut National De La Recherche Agronomique (Inra) Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5186933A (en) * 1986-12-30 1993-02-16 Baylor College Of Medicine Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system
CA2224697A1 (en) * 1995-06-14 1997-01-03 Peng Tian Rotavirus enterotoxin nsp4 and methods of using same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007941A1 (en) * 1990-10-25 1992-05-14 University Of Saskatchewan Assembled viral particles and their use in a vaccine to rotaviral disease
WO2001027335A1 (en) * 1999-10-14 2001-04-19 Baylor College Of Medicine A novel adjuvant
WO2001066566A2 (fr) * 2000-03-07 2001-09-13 Institut National De La Recherche Agronomique (Inra) Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CRAWFORD S E ET AL: "Characterization of virus-like particles produced by the expression of rotavirus capsid proteins in insect cells", JOURNAL OF VIROLOGY 1994 UNITED STATES, vol. 68, no. 9, 1994, pages 5945 - 5952, XP002289212, ISSN: 0022-538X *
See also references of WO0236172A3 *
ZENG C Q-Y ET AL: "IMMUNIZATION OF MICE WITH THE VIRAL ENTEROTOXIN INDUCES HOMOTYPIC AND HETEROTYPIC PROTECTION AGAINST ROTAVIRUS DIARRHEA", GASTROENTEROLOGY, W.B.SAUNDERS COMPANY, PHILADELPHIA, US, vol. 120, no. SUPPL 5, April 2001 (2001-04-01), pages A214, XP009035735, ISSN: 0016-5085 *
ZHANG MINGDONG ET AL: "A functional NSP4 enterotoxin peptide secreted from rotavirus-infected cells", JOURNAL OF VIROLOGY, vol. 74, no. 24, December 2000 (2000-12-01), pages 11663 - 11670, XP002303656, ISSN: 0022-538X *

Also Published As

Publication number Publication date
WO2002036172A3 (en) 2002-09-19
AU2002220025A1 (en) 2002-05-15
CA2427809A1 (en) 2002-05-10
WO2002036172A2 (en) 2002-05-10
EP1349571A2 (de) 2003-10-08

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