EP1380653A4 - Testverfahren für lupus-anticoagulans und testreagenz - Google Patents

Testverfahren für lupus-anticoagulans und testreagenz

Info

Publication number
EP1380653A4
EP1380653A4 EP02705339A EP02705339A EP1380653A4 EP 1380653 A4 EP1380653 A4 EP 1380653A4 EP 02705339 A EP02705339 A EP 02705339A EP 02705339 A EP02705339 A EP 02705339A EP 1380653 A4 EP1380653 A4 EP 1380653A4
Authority
EP
European Patent Office
Prior art keywords
inhibitory activity
assaying
assay reagent
blood coagulation
lupus anticoagulant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP02705339A
Other languages
English (en)
French (fr)
Other versions
EP1380653A1 (de
EP1380653B1 (de
Inventor
Tatsuya Atsumi
Takao Koike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of EP1380653A1 publication Critical patent/EP1380653A1/de
Publication of EP1380653A4 publication Critical patent/EP1380653A4/de
Application granted granted Critical
Publication of EP1380653B1 publication Critical patent/EP1380653B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP02705339A 2001-03-19 2002-03-19 Testverfahren für lupus-anticoagulans und testreagenz Expired - Lifetime EP1380653B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001077366 2001-03-19
JP2001077366 2001-03-19
PCT/JP2002/002599 WO2002074972A1 (fr) 2001-03-19 2002-03-19 Methode de dosage d'anticoagulant lupique et reactif de dosage

Publications (3)

Publication Number Publication Date
EP1380653A1 EP1380653A1 (de) 2004-01-14
EP1380653A4 true EP1380653A4 (de) 2004-09-22
EP1380653B1 EP1380653B1 (de) 2007-10-10

Family

ID=18934131

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02705339A Expired - Lifetime EP1380653B1 (de) 2001-03-19 2002-03-19 Testverfahren für lupus-anticoagulans und testreagenz

Country Status (6)

Country Link
US (1) US7244574B2 (de)
EP (1) EP1380653B1 (de)
JP (1) JP4134300B2 (de)
AT (1) ATE375398T1 (de)
DE (1) DE60222878D1 (de)
WO (1) WO2002074972A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117825681A (zh) * 2023-12-26 2024-04-05 米度医疗科技（中山）有限公司 一种狼疮抗凝物全液体试剂及其制备方法
WO2025197918A1 (ja) * 2024-03-19 2025-09-25 積水メディカル株式会社 試薬組成物及びその製造方法、並びに検査方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000002925A1 (en) * 1998-07-10 2000-01-20 Gradipore Limited Lupus anticoagulant antibody to f1 region of prothrombin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000002925A1 (en) * 1998-07-10 2000-01-20 Gradipore Limited Lupus anticoagulant antibody to f1 region of prothrombin

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"A MONOCLONAL ANTIBODY AGAINST PROTHROMBIN FRAGMENT 1 BEHAVES LIKE A LUPUS ANTICOAGULANT", THROMBOSIS AND HAEMOSTASIS, STUTTGART, DE, vol. 81, no. 3, March 1999 (1999-03-01), pages 470 - 471, XP001007634, ISSN: 0340-6245 *
ARTHRITIS AND RHEUMATISM. SEP 2000, vol. 43, no. 9, September 2000 (2000-09-01), pages 1982 - 1993, XP002289584, ISSN: 0004-3591 *
JOURNAL OF AUTOIMMUNITY, vol. 15, no. 2, September 2000 (2000-09-01), 9TH INTERNATIONAL SYMPOSIUM ON ANTIPHOSPHOLIPID ANTIBODIES; TOURS, FRANCE; SEPTEMBER 12-16, 2000, pages A38, XP009033955, ISSN: 0896-8411 *
MATSUDA J ET AL: "Phosphatidylserine-dependent antiprothrombin antibody is exclusive to patients with lupus anticoagulant", BRITISH JOURNAL OF RHEUMATOLOGY, vol. 35, no. 6, 1996, pages 589 - 591, XP009033948, ISSN: 0263-7103 *

Also Published As

Publication number Publication date
ATE375398T1 (de) 2007-10-15
WO2002074972A1 (fr) 2002-09-26
JP4134300B2 (ja) 2008-08-20
US7244574B2 (en) 2007-07-17
US20040110242A1 (en) 2004-06-10
JPWO2002074972A1 (ja) 2004-07-08
EP1380653A1 (de) 2004-01-14
EP1380653B1 (de) 2007-10-10
DE60222878D1 (de) 2007-11-22

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