EP1381365A4 - Sulfonamides pyrrolidines - Google Patents

Sulfonamides pyrrolidines

Info

Publication number: EP1381365A4
Authority: EP; European Patent Office
Prior art keywords: sulfonamides; pyrrolidine; pyrrolidine sulfonamides
Prior art date: 2001-03-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02757820A

Other languages

German (de)

English (en)

Other versions

EP1381365A1 (fr

Inventor

Dashyant Dhanak

Steven D Knight

Jian Jin

Ralph A Rivero

Anthony Sapienza

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-29

Filing date

2002-03-28

Publication date

2005-03-23

2002-03-28 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

2004-01-21 Publication of EP1381365A1 publication Critical patent/EP1381365A1/fr

2005-03-23 Publication of EP1381365A4 publication Critical patent/EP1381365A4/fr

Status Withdrawn legal-status Critical Current

Links

LPPOVVJDAVMOET-UHFFFAOYSA-N pyrrolidine-1-sulfonamide Chemical class NS(=O)(=O)N1CCCC1 LPPOVVJDAVMOET-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EP02757820A 2001-03-29 2002-03-28 Sulfonamides pyrrolidines Withdrawn EP1381365A4 (fr)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US27959201P	2001-03-29	2001-03-29
US27961001P	2001-03-29	2001-03-29
US279610P		2001-03-29
US279592P		2001-03-29
PCT/US2002/009445 WO2002078707A1 (fr)	2001-03-29	2002-03-28	Sulfonamides pyrrolidines

Publications (2)

Publication Number	Publication Date
EP1381365A1 EP1381365A1 (fr)	2004-01-21
EP1381365A4 true EP1381365A4 (fr)	2005-03-23

Family

ID=26959764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02757820A Withdrawn EP1381365A4 (fr)	2001-03-29	2002-03-28	Sulfonamides pyrrolidines

Country Status (3)

Country	Link
EP (1)	EP1381365A4 (fr)
JP (1)	JP2004524355A (fr)
WO (1)	WO2002078707A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003048154A1 (fr)	2001-12-04	2003-06-12	Actelion Pharmaceuticals Ltd	Nouveaux derives de quinoleines
US7750161B2 (en)	2003-09-26	2010-07-06	Daniel Bur	Pyridine derivatives
MX2007004293A (es)	2004-10-12	2007-06-18	Actelion Pharmaceuticals Ltd	1[2-(4-bencil-4-hidroxi-piperidin-1-il)-etil]-3-(2-metil-quinolin -4-il)-urea como la sal de sulfato cristalina.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9612884D0 (en) *	1996-06-20	1996-08-21	Smithkline Beecham Plc	Novel compounds

2002
- 2002-03-28 JP JP2002576973A patent/JP2004524355A/ja active Pending
- 2002-03-28 EP EP02757820A patent/EP1381365A4/fr not_active Withdrawn
- 2002-03-28 WO PCT/US2002/009445 patent/WO2002078707A1/fr not_active Ceased

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number	Publication date
WO2002078707A1 (fr)	2002-10-10
EP1381365A1 (fr)	2004-01-21
JP2004524355A (ja)	2004-08-12

Legal Events

Date	Code	Title	Description
2003-12-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-01-21	17P	Request for examination filed	Effective date: 20031020
2004-01-21	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2004-01-21	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2005-03-23	A4	Supplementary search report drawn up and despatched	Effective date: 20050209
2005-03-23	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 07D 409/12 B Ipc: 7C 07D 409/14 B Ipc: 7A 61K 31/496 A
2007-03-07	17Q	First examination report despatched	Effective date: 20070206
2007-08-04	GRAP	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOSNIGR1
2007-09-05	RIC1	Information provided on ipc code assigned before grant	Ipc: A61P 25/30 20060101ALI20070731BHEP Ipc: A61P 25/28 20060101ALI20070731BHEP Ipc: A61P 25/24 20060101ALI20070731BHEP Ipc: A61P 25/18 20060101ALI20070731BHEP Ipc: A61P 11/06 20060101ALI20070731BHEP Ipc: A61P 9/12 20060101ALI20070731BHEP Ipc: A61P 9/10 20060101ALI20070731BHEP Ipc: A61P 9/04 20060101ALI20070731BHEP Ipc: A61P 9/00 20060101ALI20070731BHEP Ipc: C07D 409/12 20060101ALI20070731BHEP Ipc: C07D 409/14 20060101ALI20070731BHEP Ipc: A61K 31/496 20060101AFI20070731BHEP
2008-06-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2008-07-23	18D	Application deemed to be withdrawn	Effective date: 20071228

Publication	Publication Date	Title
GB2390945B (en)	2004-03-10	Switching circuitry
EP1387679A4 (fr)	2004-08-11	Sulfonamides
EP1399137A4 (fr)	2005-12-14	Sulfonamides
IL158626A0 (en)	2004-05-12	Sulfonamides
AU2002359464A8 (en)	2003-06-17	Angiopioetin related factors
EP1385841A4 (fr)	2005-03-02	Sulfonamides
EP1385495A4 (fr)	2005-12-21	Sulfonamides
EP1385830A4 (fr)	2005-08-17	Sulfonamides
GB0114627D0 (en)	2001-08-08	Partitioned can
AU2002309524A1 (en)	2002-10-15	Pyrrolidine sulfonamides
EP1381365A4 (fr)	2005-03-23	Sulfonamides pyrrolidines
GB0115457D0 (en)	2001-08-15	Letetr plates
GB0103763D0 (en)	2001-04-04	Pak-Gep Construct
EP1355643A4 (fr)	2004-11-17	Epoxyvibsanine b
GB0108861D0 (en)	2001-05-30	Matchit
AU2002255943A1 (en)	2002-10-15	Pyrrolidine sulfonamides
AU2002258632A1 (en)	2002-10-15	Pyrrolidine sulfonamides
AU2002306901A1 (en)	2002-10-15	Pyrrolidine sulfonamides
GB0111831D0 (en)	2001-07-04	Former
GB0127639D0 (en)	2002-01-09	Project ccfc
PL112719U1 (en)	2003-06-02	Block
PL112625U1 (en)	2003-04-22	Block
AU145448S (en)	2001-09-27	Block
AU2002256482A1 (en)	2002-11-18	Sulfonamides
AU2002308630A1 (en)	2002-11-18	Sulfonamides