EP1383865A4 - Verfahren zur herstellung von tyrosin, zimtsäure und para-hydroxyzimtsäure - Google Patents

Verfahren zur herstellung von tyrosin, zimtsäure und para-hydroxyzimtsäure

Info

Publication number: EP1383865A4
Authority: EP; European Patent Office
Prior art keywords: acid; para; tyrosine; production; methods
Prior art date: 2001-05-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02741998A

Other languages

English (en)

French (fr)

Other versions

EP1383865A2 (de

Inventor

Wei Wei Qi

Fateme Sima Sariaslani

Xiao-Song Tang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-04

Filing date

2002-05-03

Publication date

2004-11-10

2002-05-03 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

2004-01-28 Publication of EP1383865A2 publication Critical patent/EP1383865A2/de

2004-11-10 Publication of EP1383865A4 publication Critical patent/EP1383865A4/de

Status Withdrawn legal-status Critical Current

Links

WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 title 1
WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 title 1
OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 title 1
229930016911 cinnamic acid Natural products 0.000 title 1
235000013985 cinnamic acid Nutrition 0.000 title 1
NGSWKAQJJWESNS-UHFFFAOYSA-N cis-para-coumaric acid Natural products OC(=O)C=CC1=CC=C(O)C=C1 NGSWKAQJJWESNS-UHFFFAOYSA-N 0.000 title 1
WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 title 1
NGSWKAQJJWESNS-ZZXKWVIFSA-N trans-4-coumaric acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-N 0.000 title 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/225—Tyrosine; 3,4-Dihydroxyphenylalanine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EP02741998A 2001-05-04 2002-05-03 Verfahren zur herstellung von tyrosin, zimtsäure und para-hydroxyzimtsäure Withdrawn EP1383865A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US28870101P	2001-05-04	2001-05-04
US288701P		2001-05-04
PCT/US2002/018551 WO2002090523A2 (en)	2001-05-04	2002-05-03	Methods for the production of tyrosine, cinnamic acid and para-hydroxycinnamic acid

Publications (2)

Publication Number	Publication Date
EP1383865A2 EP1383865A2 (de)	2004-01-28
EP1383865A4 true EP1383865A4 (de)	2004-11-10

Family

ID=23108250

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02741998A Withdrawn EP1383865A4 (de)	2001-05-04	2002-05-03	Verfahren zur herstellung von tyrosin, zimtsäure und para-hydroxyzimtsäure

Country Status (4)

Country	Link
US (3)	US20050148054A1 (de)
EP (1)	EP1383865A4 (de)
JP (1)	JP2005522180A (de)
WO (1)	WO2002090523A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7378261B2 (en) *	2003-04-14	2008-05-27	E.I. Du Pont De Nemours And Company	Method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium
EP1646712A4 (de) *	2003-04-14	2008-10-22	Du Pont	Verfahren zur herstellung von para-hydroxystyren mittels biokatalytischer decarboxylierung von para-hydroxyzimtsäure in einem zweiphasen-reaktionsmedium
US8003356B2 (en) *	2004-04-20	2011-08-23	E. I. Du Pont De Nemours And Company	Methods for the preparation of para-hydroxycinnamic acid and cinnamic acid at alkaline pH
EP1589112A1 (de) *	2004-04-21	2005-10-26	Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO	Mikrobielle Herstellung aromatischer Säuren
EP2368905A3 (de) *	2004-12-17	2012-08-29	Metanomics GmbH	Verfahren zur Steuerung der Herstellung von Feinchemikalien
CA2598792A1 (en) *	2005-03-02	2006-09-08	Metanomics Gmbh	Process for the production of fine chemicals
US7700328B2 (en) *	2006-06-07	2010-04-20	E.I. Du Pont De Nemours And Company	Method for producing an L-tyrosine over-producing bacterial strain
US20070299276A1 (en) *	2006-06-22	2007-12-27	Andrew Edward Feiring	Preparation of fluoroalkoxystyrenes
US7572612B2 (en)	2006-07-11	2009-08-11	E.I. Du Pont De Nemours And Company	Method of production of para-hydroxycinnamic acid using a thermostable TAL enzyme
US20080102499A1 (en) *	2006-10-27	2008-05-01	Lori Jean Templeton	Method of enhancing L-tyrosine production in recombinant bacteria
JP2011223981A (ja) *	2010-03-31	2011-11-10	Kobe Univ	桂皮酸の製造方法
US20120196339A1 (en) *	2011-01-31	2012-08-02	Los Alamos National Security Llc	Production of industrially relevant compounds in prokaryotic organisms
US9150884B2 (en)	2011-03-08	2015-10-06	Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University	Microbial conversion of glucose to styrene and its derivatives
AT516155B1 (de) *	2015-03-10	2016-03-15	Universität Graz	Biokatalytisches Verfahren zur Herstellung von p-Vinylphenolen
CN105087387B (zh) *	2015-07-14	2018-10-26	厦门欧米克生物科技有限公司	一株酵母菌及利用其发酵生产天然肉桂酸的方法
US11136559B2 (en)	2017-01-27	2021-10-05	Wisconsin Alumni Research Foundation	Engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same
US12378567B2 (en)	2017-02-16	2025-08-05	Wisconsin Alumni Research Foundation	Arogenate dehydrogenase polynucleotides, polypeptides and methods of using the same
US11543354B2 (en) *	2019-04-15	2023-01-03	Tarkett Usa Inc.	Quantitative detection of non-fluorine anti-soil using a fluorescent trace indicator
WO2025160464A1 (en) *	2024-01-26	2025-07-31	Cellibre, Inc.	Engineered cells and methods for the synthesis of caffeoyltyramine and feruloyltyramine
CN118813512B (zh) *	2024-08-28	2025-10-17	杭州唯铂莱生物科技有限公司	一种生产对羟基肉桂酸的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001011071A2 (en) *	1999-08-06	2001-02-15	E.I. Du Pont De Nemours And Company	Bioproduction of para-hydroxycinnamic acid
WO2001068822A2 (en) *	2000-03-14	2001-09-20	Nilab Aps	Method of treating phenylketonuria and means therefor
WO2002010407A1 (en) *	2000-07-27	2002-02-07	E.I. Dupont De Nemours And Company	Bioproduction of para-hydroxycinnamic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4946790A (en) *	1987-02-06	1990-08-07	Mitsui Toatsu Chemicals, Inc.	Recombinant plasmid for the expression of L-phenylalanine ammonia-lyase and transformed strain carrying same
US6521748B2 (en) *	1999-08-06	2003-02-18	E. I. Du Pont De Nemours And Company	Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide

2002
- 2002-05-03 EP EP02741998A patent/EP1383865A4/de not_active Withdrawn
- 2002-05-03 WO PCT/US2002/018551 patent/WO2002090523A2/en not_active Ceased
- 2002-05-03 JP JP2002587585A patent/JP2005522180A/ja not_active Ceased
- 2002-05-03 US US10/476,198 patent/US20050148054A1/en not_active Abandoned
- 2002-05-03 US US10/138,970 patent/US7105326B2/en not_active Expired - Lifetime
2006
- 2006-07-14 US US11/486,826 patent/US7303900B2/en not_active Expired - Fee Related

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001011071A2 (en) *	1999-08-06	2001-02-15	E.I. Du Pont De Nemours And Company	Bioproduction of para-hydroxycinnamic acid
WO2001068822A2 (en) *	2000-03-14	2001-09-20	Nilab Aps	Method of treating phenylketonuria and means therefor
WO2002010407A1 (en) *	2000-07-27	2002-02-07	E.I. Dupont De Nemours And Company	Bioproduction of para-hydroxycinnamic acid

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEN DAWEI ET AL: "Phenylalanine hydroxylase from Chromobacterium violaceum. Uncoupled oxidation of tetrahydropterin and the role of iron in hydroxylation", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 40, 2 October 1998 (1998-10-02), pages 25594 - 25601, XP002295992, ISSN: 0021-9258 *
ONISHI A ET AL: "CLONING AND EXPRESSION OF CHROMOBACTERIUM-VIOLACEUM PHENYLALANINE HYDROXYLASE IN ESCHERICHIA-COLI AND COMPARISON OF AMINO ACID SEQUENCE WITH MAMMALIAN AROMATIC AMINO ACID HYDROXYLASES", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 28, 1991, pages 18454 - 18459, XP002295993, ISSN: 0021-9258 *
See also references of WO02090523A3 *
SONG J ET AL: "PhhB, a Pseudomonas aeruginosa homolog of mammalian pterin 4a-carbinolamine dehydratase/DCoH, does not regulate expression of phenylalanine hydroxylase at the trascriptional level", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 181, no. 9, May 1999 (1999-05-01), pages 2789 - 2796, XP002902005, ISSN: 0021-9193 *
ZHAO GENSHI ET AL: "Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4-alpha-carbinolamine dehydratase/DCoH as part of a three-component gene cluster", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 91, no. 4, 1994, pages 1366 - 1370, XP002295994, ISSN: 0027-8424 *

Also Published As

Publication number	Publication date
WO2002090523A2 (en)	2002-11-14
US7105326B2 (en)	2006-09-12
WO2002090523A3 (en)	2003-11-06
US20060275881A1 (en)	2006-12-07
US20050148054A1 (en)	2005-07-07
US7303900B2 (en)	2007-12-04
EP1383865A2 (de)	2004-01-28
JP2005522180A (ja)	2005-07-28
US20030079255A1 (en)	2003-04-24

Legal Events

Date	Code	Title	Description
2003-12-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-01-28	17P	Request for examination filed	Effective date: 20031119
2004-01-28	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2004-03-24	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 12N 9/02 B Ipc: 7C 12P 1/00 A Ipc: 7C 12N 9/88 B Ipc: 7C 12N 9/00 B Ipc: 7C 12P 7/40 B Ipc: 7C 12N 9/04 B
2004-11-10	A4	Supplementary search report drawn up and despatched	Effective date: 20040928
2007-02-14	17Q	First examination report despatched	Effective date: 20070116
2011-05-13	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2011-06-15	18D	Application deemed to be withdrawn	Effective date: 20101201

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