EP1395324B1 - Catheter multilumiere servant a reduire l'ischemie des membres - Google Patents

Catheter multilumiere servant a reduire l'ischemie des membres Download PDF

Info

Publication number
EP1395324B1
EP1395324B1 EP01983207A EP01983207A EP1395324B1 EP 1395324 B1 EP1395324 B1 EP 1395324B1 EP 01983207 A EP01983207 A EP 01983207A EP 01983207 A EP01983207 A EP 01983207A EP 1395324 B1 EP1395324 B1 EP 1395324B1
Authority
EP
European Patent Office
Prior art keywords
catheter
lumen
patient
distal end
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP01983207A
Other languages
German (de)
English (en)
Other versions
EP1395324A2 (fr
Inventor
Laksen Sirimanne
Anthony Viole
Sean O'leary
Wolfgang Warner
Steven Bolling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orqis Medical Corp
Original Assignee
Orqis Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orqis Medical Corp filed Critical Orqis Medical Corp
Publication of EP1395324A2 publication Critical patent/EP1395324A2/fr
Application granted granted Critical
Publication of EP1395324B1 publication Critical patent/EP1395324B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3613—Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659—Cannulae pertaining to extracorporeal circulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/152—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel branching on and drawing blood from a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/857—Implantable blood tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/865—Devices for guiding or inserting pumps or pumping devices into the patient's body
    • A61M60/867—Devices for guiding or inserting pumps or pumping devices into the patient's body using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
    • A61M2025/0031—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/0037—Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side

Definitions

  • the present invention relates to a multilumen catheter and, in particular, to multilumen catheters designed to prevent ischemia in patients when the catheter is positioned within the body.
  • Some of the percutaneous procedures involve removing blood from the body and subsequently reluming it to the body.
  • dialysis treatment involves first removing blood from the patient's circulatory system, treating the blood outside of the body, and then returning the blood to the patient's circulatory system to perfuse the various tissues and organs.
  • cannulae with large carrying capacity may be necessary.
  • By maximizing the cross-sectional area of the cannula the volume of blood that may be removed and/or returned to the patient's vascular system via the cannula is maximized.
  • One approach to maximize the cross-sectional area of the cannula involves using either two single lumen catheters or a multi-luman catheter.
  • one lumen would function to withdraw blood and one would function to return blood to the patient.
  • One problem with using two single lumen catheters is that it subjects the patient to multiple percutaneous insertion procedures, which complicates the procedure and increases the potential for infection and other complications. Therefore, it would be desirable to have a catheter assembly which could be inserted into the patient through a single insertion site.
  • Multilumen catheters in various forms have been employed for this purpose.
  • multilumen catheters have been made with two, three or more lumens to serve various aspiration and infusion functions, including extracting and returning blood to vessels, taking blood samples for testing and providing medications to the patient's vascular system.
  • Simple multilumen catheters have been made by providing two round catheters of equal or nearly equal length joined by a web, or thin strip. This approach is described in U.S. Patent No. 5,776,111 to Tesio .
  • Other multilumen catheter designs have a unitary body with at least one septum dividing the lumens which extend from a proximal to a distal end.
  • EP-A-0.711,574 describes catheters having round lumens arranged in side-by-side relationship and separated by a thin wall which enlarges into reinforcement zones to either end of the wall, the whole being contained within a generally elliptical outer surface.
  • US-A-4,692,141 describes a double lumen catheter having an elongated tube with a proximal first cylindrical portion having an internal divider to define a pair of discrete lumens including a shorter lumen opening at approximately the distal end of the first cylindrical portion, and a longer lumen opening at the distal end of the elongated tube.
  • the distal end of the tube has a smooth conical tapered tip that smoothly merges with the distal second cylindrical portion of the elongated tube.
  • the lumens are "D" shaped in the first cylindrical portion.
  • a plurality of outlet holes are provided in the vicinity of the conical tapered tip, and the shorter lumen opens at an aperture having a bevel.
  • US-A-5,961,486 describes a multiple lumen catheter which connects between a vein of a patient and a blood treatment device. The catheter and the lumens thereof each define distal ends which are positioned within the vein.
  • Blood is withdrawn from the vein through one of the lumens at a flow rate of at least about 200 ml./min. while also inserting blood into the vein through another of said lumens at a similar flow rate.
  • the distal ends of the lumens are longitudinally spaced from each other by no more than about 5mm.
  • multilumen catheters require only a single puncture of the epidermis, their performance is limited in at least two ways. For one, the outer perimeter of the multilumen catheter cannot exceed the inner diameter of the vessel into which it is inserted. Furthermore, the already limited cross-sectional area must be divided into at least two lumens, one for withdrawal and one for return. Thus the carrying capacity of each lumen is further reduced. To supply the same amount of blood, the velocity and pressure of the blood in the lumens must increase over what it would be in the vessel itself. This has the potential to cause damage to the vessel as blood comes jetting out of the return lumen. Also, it may put further stress upon blood cells, even causing hemolysis. Thus, multilumen catheters must be made as large as possible to carry enough blood at satisfactory conditions.
  • the present invention provides a multilumen catheter for directing the flow of blood through a patient through a single cannulation site, said catheter comprising: a catheter having a proximal end, a first distal end and a second distal end; said first distal end extending distally further from the proximal end than the second distal end; a first lumen extending between said first distal end and said proximal end; and a second lumen extending between said second distal end and said proximal end, characterised in that said catheter comprises means for biasing said first distal end towards a J-shape so that said first lumen is curved at said first distal end such that blood exiting the lumen is directed back along the multilumen catheter.
  • At least one aperture may be formed in one of the first or second lumens positioned near the proximal end so that the aperture permits active maintenance or enhancement of perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment.
  • the multilumen catheter further comprises a third lumen with distal and proximal ends configured to be positioned entirely within the patient's vascular system. This third lumen is configured to permit the passive flow of blood downstream of the catheter site to maintain or enhance perfusion.
  • a connector formed in the shape of a Y (“Y-connector”) is positioned at the proximal end of the multilumen catheter.
  • One leg of the Y-connector is in fluid communication with the first lumen and the other leg of the Y-connector is in fluid communication with the second lumen.
  • an outflow conduit of a pumping system is fluidly engaged to one lumen of the multilumen catheter and an inflow conduit of the same system is fluidly engaged to the other lumen.
  • the inflow and outflow conduits are fluidly coupled to a pump so that, when connected to the patient, the pump circulates blood from one distal end of the multilumen catheter to the other distal end, and also through at least one aperture in one of the first or second lumens positioned near the proximal end.
  • the multilumen catheter of the present invention is incorporated into an extracardiac pumping system for supplementing blood circulation in a patient without any component thereof being connected to the patient's heart. Such a system is described in U.S. Patent No.
  • the system includes, in addition to the multilumen catheter, a pump configured to pump blood through the patient at subcardiac rates, an inflow conduit fluidly coupled to the pump to divert blood to the pump from a first blood vessel, and an outflow conduit fluidly coupled to the pump to direct blood from the pump to a second blood vessel.
  • the method comprises the step of inserting the multilumen catheter described above into the patient at a single cannulation site of a first blood vessel, locating the catheter such that a first lumen may be in fluid communication with a second blood vessel and a second lumen may be in fluid communication with the first blood vessel, withdrawing blood from one of said blood vessels through one of the first or said second lumens, and delivering blood through the other of said first or second lumens so that blood is delivered upstream and downstream of the cannulation site.
  • the multilumen catheter preferably is of unitary construction and requires only one entry point into the patient's body.
  • the multilumen catheter 10 comprises at least two lumens: a first lumen 12 and a second lumen 14.
  • the first lumen 12 extends from a proximal end 16 of the multilumen catheter 10 to a first distal end 18.
  • the second lumen 14 extends from the proximal end 16 of the multilumen catheter 10 to a second distal end 20.
  • the lumens 12, 14 of the multilumen catheter 10 may be arranged in one of many different ways.
  • the two lumens may be joined in a side-by-side manner, forming a "figure-8" when viewed from the proximal end 16.
  • a single cylindrical catheter housing may contain within it two or more side-by-side lumens.
  • a cylindrical catheter housing could be formed with a diametral septum, i.e. a wall, extending across the cylinder at a diameter.
  • a cylindrical housing with concentrically positioned lumens is also contemplated.
  • the first distal end 18 may be formed with one or more distal apertures 22, although such apertures may also be located in the second distal end 20.
  • the distal apertures 22 may be positioned close together or spaced circumferentially around the distal end.
  • the apertures 22 serve to decrease the pressure drop across the cannula tip, thereby minimizing damage to vessel walls from jetting effects. It may also be appropriate to practice methods for directing blood flow so as to minimize damage to vessel walls from jetting effects and from the recoil effect on the catheter of blood exiting a catheter.
  • the catheter 10 may further comprise a tapered tip 24 at the first distal end 18, which facilitates insertion and threading of the catheter into the patient.
  • the catheter 10 may also further comprise a tapered tip 26 at the second distal end 20.
  • One preferred design of the multilumen catheter further comprises a set of apertures 28 positioned on the catheter 10 near the proximal end 16.
  • the apertures 28 are formed on at least one lumen of the catheter to provide for fluid communication between one of the lumens 12, or 14 of the multilumen catheter 10 and the blood vessel in which it resides.
  • a radiopaque marker 30 may be positioned at the distal end 18 of the multilumen catheter 10.
  • the multilumen catheter could further comprise markings 32 near the proximal end of the multilumen catheter which are a known distance from one or more of the distal ends. These markings 32, as well as the marker 30 can be used to accurately position the catheter when applied to the patient
  • the multilumen catheter 110 comprises a third lumen 134 extending between a proximal end 136 and a distal end 138.
  • the lumen 134 is positioned and sized such that when the multilumen catheter 110 is applied to the patient (described below), the lumen resides entirely within the patient's body.
  • the lumen 134 may be connected to the catheter 110 in a variety of ways.
  • the purpose of the third lumen 134 is to pemit the passive flow of blood downstream to the catheter to enhance perfusion.
  • the design - shown in Figure 2 also may have apertures 128 disposed near the proximal end 116 of the multilumen catheter 110.
  • this design may further comprise a tapered tip 140 at the distal end of the third lumen 134 and a tapered tip 142 at the proximal end of the third lumen 134 to facilitate application of the catheter to the patient.
  • the third lumen 134 may be made of collapsible material. In the collapsed state, the third lumen 134 would conform to at least a portion of the outside surface of the multilumen catheter 110. Once applied to the patient, as described in more detail below, the lumen 134 would be expanded to the deployed state shown in Figure 2 .
  • This collapsible lumen could comprise a stone basket, or a frame similar to a stent
  • a stone basket is a structure that can be deployed within a patient's body and is used to capture objects. Here, the basket is used primarily to create a space between the catheter 110 and the vessel wall to permit the passive flow of blood downstream of the catheter site to enhance perfusion.
  • the first distal end 218 is formed in the shape of a J-tip. That is, the opening at the distal end 218 may be curved such that blood exiting the lumen 212 is directed back along the multilumen catheter 210. Distal aperture(s) 222 may be formed at the bend of the J-tip so that blood also exits the lumen 212 and flows distal of the catheter 210.
  • the "J" shape of the multi-lumen catheter tip may be formed and/or maintained by pre-loading it with a coil or with wire reinforcement, or by using a shape-memory material to create and maintain this shape. If the catheter is inserted so that the tip is straight and the "J" shape is deployed after the catheter inserted into the patient, the catheter may comprise a tapered tip at the first distal end 218, as described above.
  • multilumen catheter 310 comprising a Y-connector 334 formed at the proximal end of the multilumen catheter 310.
  • the lumens are separated in any suitable way such that fluid communication is provided between the distal end 318 of the lumen 312 of the multilumen catheter 310 and the proximal end 336 of one leg of the Y-connector 334, and fluid communication is provided between the distal end 320 of the lumen 314 of the catheter 310 and the proximal end 338 of one leg of the Y-connector 334.
  • any of the multilumen catheters described herein may be made from various materials to improve their viability in long-term treatment applications.
  • the biocompatibility of the catheter be improved compared to uncoated catheters to prevent adverse reactions such as compliment activation and the like.
  • the interior lumens of the catheters can be coated with biocompatible materials.
  • anti-bacterial coatings are also known in the art. Such coatings may be very useful on the outer surface of the catheter. This is especially true at or about where the catheter enters the patient's skin. At such a location, the patient is vulnerable to introduction of bacteria into the body cavity. Anti-bacterial coatings can reduce the likelihood of infection and thus improve the viability of long-term treatments.
  • the multilumen catheter of the present invention may be integrated into a pumping system, such as the one described in more detail in U.S. Patent No. 6,200,260 .
  • a pumping system such as the one described in more detail in U.S. Patent No. 6,200,260 .
  • a system comprises the multilumen catheter 10, an inflow conduit 38, an outflow conduit 40 and a pump 42.
  • One end of the outflow conduit 40 may be connected to the proximal end of the lumen 12, while the other end is connected to the inlet of the pump 42.
  • One end of the inflow conduit 38 may be connected to the proximal end of the lumen 14, while the other end is connected to the outlet of the pump 42. This results in a flow from the first distal end 18 to the second distal end 20.
  • the flow direction may be reversed using the same multilumen catheter, resulting in a flow from distal end 20 to distal end 18.
  • the outflow conduit 40 is connected to the proximal end of lumen 14 and the inflow conduit 38 is connected to the proximal end of lumen 12.
  • the present multilumen catheter 10 when incorporated into a pumping system may be applied to a patient in an arterial-arterial fashion. Where the multilumen catheter 10 is inserted into the femoral artery 44 of the patient 46.
  • the radiopaque marker 30 which may be incorporated into the distal end 18 of the multilumen catheter is used to track the insertion of the catheter so that the catheter may be positioned at a desired site within the patient's vascular system. As mentioned above, markings 32 on the proximal end could also be used to locate the distal end or ends.
  • the distal end 18 may be located in the aortic arch 48.
  • the pump draws blood from the patient's vascular system in the area near the distal end 18 and into the lumen 12. This blood is further drawn into the lumen of the conduit 40 and into the pump 42. The pump 42 then expels the blood into the lumen of the outflow conduit 38.
  • This lumen carries the blood into the lumen 14 of the multilumen catheter 10 and back into the patient's vascular system in the area near the distal end 20.
  • the apertures 28 and/or the third lumen 134 provide blood flow to the patient's vasculature downstream of where the multilumen catheter resides in the vasculature to maintain or enhance perfusion of blood.
  • the blood flow in the multilumen catheter may be reversed. In that case, blood is drawn from the patient through distal end 20 and returned to the patient through distal end 18.
  • the multilumen catheter 10 comprises features that will maintain or increase the blood flow to downstream tissue when the catheter is inserted into the patient.
  • the apertures 28 provide for fluid communication between at least one lumen 12 or 14 and the patient's blood vessel. The apertures 28, thus, provides active perfusion of the downstream tissues.
  • the lumen 134 of the design shown in Figure 2 is located entirely within the vessel when the catheter 110 is inserted into the patient.
  • the lumen provides a pathway for blood flow to tissue downstream of the catheter so that the catheter 110 may maintain or increase the flow of blood to downstream tissue.
  • the lumen 134 thus, provides passive perfusion. If desired, apertures may be included in one of the other two lumens to supplement passive perfusion with active perfusion.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • External Artificial Organs (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Surgical Instruments (AREA)

Claims (23)

  1. Cathéter multilumière destiné à diriger le flux sanguin chez un patient à travers un site de canulation unique, ledit cathéter comprenant :
    un cathéter (210) présentant une extrémité proximale (216), une première extrémité distale (218) et une deuxième extrémité distale (220), ladite première extrémité distale (218) s'étendant de manière distale plus loin de l'extrémité proximale (216) que la deuxième extrémité distale (220) ;
    une première lumière (212) s'étendant entre ladite première extrémité distale (218) et ladite extrémité proximale (216) ; et
    une deuxième lumière (214) s'étendant entre ladite deuxième extrémité distale (220) et ladite extrémité proximale (216), caractérisé en ce que ledit cathéter comprend un moyen destiné à solliciter ladite première extrémité distale (218) vers une forme en J de sorte que ladite première lumière (212) est incurvée au niveau de ladite première extrémité distale (218) de sorte que le sang sortant de la lumière (212) est redirigé le long du cathéter multilumière (210).
  2. Cathéter multilumière selon la revendication 1, comprenant en outre un moyen destiné à maintenir ou renforcer une perfusion sur le système vasculaire du patient et à minimiser une ischémie en aval d'un point d'entrée dudit cathéter dans un vaisseau sanguin lorsque ledit cathéter est inséré dans le patient.
  3. Cathéter multilumière selon la revendication 2, dans lequel le moyen destiné à maintenir ou renforcer une perfusion comprend un moyen de perfusion actif.
  4. Cathéter multilumière selon la revendication 3, dans lequel le moyen de perfusion actif comprend une ouverture (222, 226).
  5. Cathéter multilumière selon la revendication 3, dans lequel le moyen de perfusion actif est au moins une ouverture (226) dans l'une desdites lumières (212, 214) positionnées près de l'extrémité proximale (216).
  6. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel le moyen destiné à maintenir ou renforcer une perfusion comprend un moyen de perfusion passif.
  7. Cathéter multilumière selon la revendication 6, dans lequel le moyen de perfusion passif est une troisième lumière présentant une extrémité distale et une extrémité proximale configurées pour être positionnées entièrement au sein du système vasculaire du patient.
  8. Cathéter multilumière selon l'une quelconque des revendications précédentes, comprenant en outre un connecteur en Y positionné au niveau de l'extrémité proximale, où une première jambe du connecteur en Y est en communication de fluide avec ladite première lumière et une deuxième jambe dudit connecteur en Y est en communication de fluide avec ladite deuxième lumière.
  9. Cathéter multilumière selon l'une quelconque des revendications précédentes, comprenant en outre un conduit de sortie engagé de manière fluide sur une première lumière et un conduit d'entrée engagé de manière fluide sur l'autre lumière, lesdits conduits d'entrée et de sortie étant couplés de manière fluide à une pompe de sorte que, lorsqu'ils sont connectés à un patient, ladite pompe fait circuler le sang d'une première extrémité distale dudit cathéter multilumière à l'autre extrémité distale et également à travers au moins une ouverture.
  10. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel la première extrémité distale est inclinée.
  11. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel la deuxième extrémité distale est inclinée.
  12. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel l'une desdites extrémités distales comprend au moins une ouverture distale.
  13. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel ladite première extrémité distale (218) comprend un bout en J comportant un coude.
  14. Cathéter multilumière selon la revendication 13, dans lequel ledit bout en J comprend une ouverture (222) positionnée au niveau de la partie la plus distale du coude.
  15. Cathéter multilumière selon l'une quelconque des revendications précédentes, comprenant en outre un marqueur radio-opaque (230), où le marqueur radio-opaque (230) peut être utilisé pour positionner le cathéter lorsque le cathéter est appliqué à un patient.
  16. Cathéter multilumière selon l'une quelconque des revendications précédentes, comprenant en outre un indicateur (232) près de l'extrémité proximale (216), où l'indicateur (232) peut être utilisé pour positionner le cathéter lorsque le cathéter est appliqué à un patient.
  17. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel l'extrémité proximale (216) comporte deux orifices.
  18. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel le cathéter est conçu pour une insertion dans un patient, le cathéter ayant une périphérie continue au niveau du site de sortie de la peau du patient.
  19. Cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel ladite première lumière (212) est incurvée au niveau de ladite première extrémité distale (218) après que le cathéter est inséré dans le patient.
  20. Cathéter multilumière selon l'une quelconque des revendications 1 à 18, dans lequel ladite première lumière (212) est incurvée au niveau de ladite première extrémité distale (218) avant que le cathéter ne soit inséré dans le patient.
  21. Système de pompage extracardiaque destiné à compléter la circulation sanguine chez un patient sans qu'aucun de ses composants ne soit connecté au coeur du patient, le système extracardiaque comprenant :
    une pompe configurée pour pomper du sang dans le patient à des débits inférieurs au débit cardiaque, ladite pompe ayant un débit moyen qui, au cours de son fonctionnement normal, est sensiblement inférieur à celui du coeur du patient lorsqu'il est sain ;
    un conduit d'entrée relié de manière fluide à la pompe pour diriger le sang vers la pompe à partir d'un premier vaisseau sanguin ;
    un conduit de sortie relié de manière fluide à la pompe pour diriger le sang de la pompe vers un deuxième vaisseau sanguin ; et
    le cathéter multilumière selon l'une quelconque des revendications précédentes, dans lequel la première lumière de celui-ci est en communication de fluide avec un premier conduit parmi ledit conduit d'entrée et ledit conduit de sortie et la seconde lumière de celui-ci est en communication de fluide avec l'autre conduit parmi ledit conduit d'entrée et ledit conduit de sortie.
  22. Système de pompage extracardiaque selon la revendication 21, dans lequel ladite première lumière est en communication de fluide avec ledit conduit de sortie et ladite deuxième lumière est en communication de fluide avec ledit conduit d'entrée.
  23. Système de pompage extracardiaque selon la revendication 21, dans lequel ladite première lumière est en communication de fluide avec ledit conduit d'entrée et ladite deuxième lumière est en communication de fluide avec ledit conduit de sortie.
EP01983207A 2001-06-06 2001-10-15 Catheter multilumiere servant a reduire l'ischemie des membres Expired - Lifetime EP1395324B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/876,281 US7048680B2 (en) 2001-06-06 2001-06-06 Multilumen catheter for minimizing limb ischemia
US876281 2001-06-06
PCT/US2001/042774 WO2002098499A2 (fr) 2001-06-06 2001-10-15 Catheter multilumiere servant a reduire l'ischemie des membres

Publications (2)

Publication Number Publication Date
EP1395324A2 EP1395324A2 (fr) 2004-03-10
EP1395324B1 true EP1395324B1 (fr) 2008-07-09

Family

ID=25367348

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01983207A Expired - Lifetime EP1395324B1 (fr) 2001-06-06 2001-10-15 Catheter multilumiere servant a reduire l'ischemie des membres

Country Status (9)

Country Link
US (4) US7048680B2 (fr)
EP (1) EP1395324B1 (fr)
JP (1) JP2004528139A (fr)
AT (1) ATE400314T1 (fr)
AU (1) AU2002214653C1 (fr)
CA (1) CA2449689A1 (fr)
DE (1) DE60134790D1 (fr)
ES (1) ES2307661T3 (fr)
WO (1) WO2002098499A2 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610004B2 (en) 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6889082B2 (en) 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6488662B2 (en) 2000-12-19 2002-12-03 Laksen Sirimanne Percutaneous catheter assembly
US6761700B2 (en) 2001-02-09 2004-07-13 Orqis Medical Corporation Extra-corporeal vascular conduit
US20020188167A1 (en) * 2001-06-06 2002-12-12 Anthony Viole Multilumen catheter for minimizing limb ischemia
US7048680B2 (en) * 2001-06-06 2006-05-23 Orqis Medical Corporation Multilumen catheter for minimizing limb ischemia
DE10261575A1 (de) * 2002-12-23 2004-07-08 Nova Lung Gmbh Vorrichtung zur Kanülierung eines Blut führenden Gefäßes und deren Verwendung zur Kanülierung von Blut führenden Gefäßen
US20050113631A1 (en) * 2003-11-12 2005-05-26 Bolling Steven F. Cannulae having a redirecting tip
US7445592B2 (en) 2004-06-10 2008-11-04 Orqis Medical Corporation Cannulae having reduced flow resistance
US20060030809A1 (en) * 2004-07-12 2006-02-09 Amir Barzilay Apparatus and method for multiple organ assist
EP1681077A1 (fr) * 2005-01-12 2006-07-19 Acrostak Corp. Dispositif de positionnement et procédure pour traitment de la cavité de résection
US20060184199A1 (en) * 2005-02-14 2006-08-17 O'leary Shawn Apparatus and methods for reducing bleeding from a cannulation site
US8721634B2 (en) 2005-07-21 2014-05-13 Covidien Lp Apparatus and method for ensuring thermal treatment of a hollow anatomical structure
US7803148B2 (en) 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
DE102006042639A1 (de) * 2006-09-01 2008-03-20 Novalung Gmbh Vorrichtung zur Kanülierung eines Blut-führenden Gefäßes
US20080082079A1 (en) 2006-09-28 2008-04-03 Tyco Healthcare Group Lp Low profile catheter assembly
US9168355B2 (en) * 2006-09-29 2015-10-27 Covidien Lp Acute hemodialysis catheter assembly
US20090259089A1 (en) * 2008-04-10 2009-10-15 Daniel Gelbart Expandable catheter for delivery of fluids
JP2009273609A (ja) 2008-05-14 2009-11-26 Nippon Sherwood Medical Industries Ltd 弁付きカテーテル
US9005154B2 (en) * 2008-09-26 2015-04-14 Covidien Lp Valved hemodialysis catheter
JP5757537B2 (ja) 2009-06-04 2015-07-29 カーディオガード メディカル リミテッド 動脈装置、動脈系、および方法
JP2011050420A (ja) * 2009-08-31 2011-03-17 Nippon Sherwood Medical Industries Ltd 弁付きカテーテル
CA2715857A1 (fr) 2009-09-30 2011-03-30 Tyco Healthcare Group Lp Catheter medical concu de facon a permettre une faible recirculation et reversibilite
JP5713732B2 (ja) 2011-03-08 2015-05-07 日本コヴィディエン株式会社 弁付きカテーテル
US20120311934A1 (en) 2011-06-07 2012-12-13 Steven Robert Abramson Draft Guard
US10107022B2 (en) 2011-06-07 2018-10-23 Henniges Automotive Schlegel Canada, Inc. Draft guard for window assembly having seals and integral fins
US8747343B2 (en) 2011-09-30 2014-06-10 Covidien Lp Hemodialysis catheter with improved side opening design
US9072867B2 (en) 2011-09-30 2015-07-07 Covidien Lp Catheter with external flow channel
JP2015128457A (ja) * 2012-04-27 2015-07-16 テルモ株式会社 塞栓物吐出カテーテル
US10143822B2 (en) 2012-07-05 2018-12-04 Covidien Lp Valved tip catheters
US9155862B2 (en) 2012-09-28 2015-10-13 Covidien Lp Symmetrical tip acute catheter
US9440045B2 (en) * 2013-02-01 2016-09-13 Cook Medical Technologies Llc Curved tip hemodialysis catheter
CN105617512B (zh) * 2015-12-24 2018-05-22 北京天助瑞畅医疗技术有限公司 导丝导引装置和导丝导引组件
TR201702278A2 (tr) * 2017-02-15 2018-09-21 T C Istanbul Medipol Ueniversitesi Bi̇r venovenöz ecmo (extracorporeal membrane oxygenation ekstrakorporeal membran oksi̇jenasyonu) kanül
WO2023192959A1 (fr) 2022-04-01 2023-10-05 Karas Richard H Systèmes de perfusion et procédés de surveillance d'oxygénation de tissu et de réduction d'ischémie des membres
CN114699635B (zh) * 2022-04-15 2023-03-24 常州乐奥医疗科技股份有限公司 一种肺泡灌洗装置

Family Cites Families (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US648862A (en) * 1899-08-03 1900-05-01 Epatha R Kreutner Ruffler for sewing-machines.
US1902418A (en) * 1931-11-02 1933-03-21 Jensen Salsbery Lab Inc Surgical instrument
US2935068A (en) * 1955-08-04 1960-05-03 Donaldson John Shearman Surgical procedure and apparatus for use in carrying out the same
US2876769A (en) * 1955-10-11 1959-03-10 Cordova Jose Juan Apparatus for oxygenating, centrifuging and changing the temperature of blood
US3017885A (en) * 1959-03-30 1962-01-23 Robicsek Francis Blood flow meter
CH461033D (fr) * 1965-05-13
US3938530A (en) * 1974-11-15 1976-02-17 Santomieri Louis Catheter
US4134402A (en) * 1976-02-11 1979-01-16 Mahurkar Sakharam D Double lumen hemodialysis catheter
US4080958A (en) * 1976-02-27 1978-03-28 Datascope Corporation Apparatus for aiding and improving the blood flow in patients
LU77252A1 (fr) * 1976-05-06 1977-08-22
US4375941A (en) * 1978-03-20 1983-03-08 Child Frank W Method and apparatus for pumping blood
FR2502499B1 (fr) * 1981-03-27 1987-01-23 Farcot Jean Christian Appareil pour la retroperfusion sanguine, destine notamment au traitement d'infarctus par injection de sang arteriel dans le sinus coronaire
US4375841A (en) * 1981-06-18 1983-03-08 Fluid Kinetics Corporation Fluid flow apparatus for accommodating a pressure drop
US4405313A (en) 1982-01-29 1983-09-20 Sisley James R Figure-eight, dual-lumen catheter and method of using
US4692141A (en) 1982-03-08 1987-09-08 Mahurkar Sakharam D Double lumen catheter
DE3214397C2 (de) * 1982-04-20 1984-07-26 Karl Dr. 6301 Pohlheim Aigner Perfusions-Doppellumenkatheter
US4464164A (en) * 1982-09-24 1984-08-07 Extracorporeal Medical Specialties, Inc. Flowrate control for a blood flow system
US4543087A (en) 1983-11-14 1985-09-24 Quinton Instrument Company Double lumen catheter tip
US4960411A (en) * 1984-09-18 1990-10-02 Medtronic Versaflex, Inc. Low profile sterrable soft-tip catheter
US4897077A (en) * 1987-05-22 1990-01-30 Kontron Inc. Method of inserting an IAB device into the body
US5059167A (en) * 1987-05-29 1991-10-22 Retroperfusion Systems, Inc. Retroperfusion and retroinfusion control apparatus, system and method
US4902272A (en) * 1987-06-17 1990-02-20 Abiomed Cardiovascular, Inc. Intra-arterial cardiac support system
CA1330285C (fr) 1987-12-22 1994-06-21 Geoffrey S. Martin Catheter a triple voie
FR2626476B1 (fr) * 1988-02-01 1997-10-17 Boussignac Georges Sonde destinee a etre introduite a l'interieur d'un corps vivant
US4944745A (en) * 1988-02-29 1990-07-31 Scimed Life Systems, Inc. Perfusion balloon catheter
US5014715A (en) * 1988-11-22 1991-05-14 Chapolini Robert J Device for measuring the impedance to flow of a natural or prosthetic vessel in a living body
US4957504A (en) * 1988-12-02 1990-09-18 Chardack William M Implantable blood pump
US4976270A (en) 1989-03-28 1990-12-11 Vanderbilt University Apparatus for continuously sampling plasma
US4995857A (en) * 1989-04-07 1991-02-26 Arnold John R Left ventricular assist device and method for temporary and permanent procedures
US4985014A (en) * 1989-07-11 1991-01-15 Orejola Wilmo C Ventricular venting loop
US5569182A (en) 1990-01-08 1996-10-29 The Curators Of The University Of Missouri Clot resistant multiple lumen catheter and method
US5374245A (en) * 1990-01-10 1994-12-20 Mahurkar; Sakharam D. Reinforced multiple-lumen catheter and apparatus and method for making the same
US5147281A (en) * 1990-04-23 1992-09-15 Advanced Medical Systems, Inc. Biological fluid pumping means and method
CA2022019C (fr) 1990-07-26 1992-12-29 Michael Black Catheter
US5087247A (en) * 1990-08-28 1992-02-11 Cardiovascular Designs, Inc. Balloon perfusion catheter
US5186713A (en) * 1990-11-01 1993-02-16 Baxter International Inc. Extracorporeal blood oxygenation system and method for providing hemoperfusion during transluminal balloon angioplasty procedures
US5766151A (en) * 1991-07-16 1998-06-16 Heartport, Inc. Endovascular system for arresting the heart
DE4126886A1 (de) 1991-08-14 1993-02-18 Hp Medica Gmbh Spuelkatheter
JP2713515B2 (ja) 1991-09-17 1998-02-16 禎祐 山内 カテーテル装置
US5437601A (en) * 1992-03-03 1995-08-01 Runge; Thomas M. Blood conduit and pulsatile cardiopulmonary bypass pump system
US5676651A (en) * 1992-08-06 1997-10-14 Electric Boat Corporation Surgically implantable pump arrangement and method for pumping body fluids
US5536250A (en) * 1994-04-01 1996-07-16 Localmed, Inc. Perfusion shunt device and method
US5344402A (en) * 1993-06-30 1994-09-06 Cardiovascular Dynamics, Inc. Low profile perfusion catheter
US5403291A (en) 1993-08-02 1995-04-04 Quinton Instrument Company Catheter with elongated side holes
US5486159A (en) 1993-10-01 1996-01-23 Mahurkar; Sakharam D. Multiple-lumen catheter
US5378230A (en) 1993-11-01 1995-01-03 Mahurkar; Sakharam D. Triple-lumen critical care catheter
US5597377A (en) * 1994-05-06 1997-01-28 Trustees Of Boston University Coronary sinus reperfusion catheter
US5542937A (en) 1994-06-24 1996-08-06 Target Therapeutics, Inc. Multilumen extruded catheter
US5472418A (en) * 1994-07-28 1995-12-05 Palestrant; Aubrey M. Flattened collapsible vascular catheter
US5554136A (en) 1994-09-07 1996-09-10 Luther Medical Products, Inc. Dual lumen infusion/aspiration catheter
US5571093A (en) 1994-09-21 1996-11-05 Cruz; Cosme Multiple-lumen catheter
EP0711574A1 (fr) 1994-11-10 1996-05-15 Med-Pro Design, Inc. Cathéter à double passages ronds
US5616137A (en) * 1995-02-22 1997-04-01 Minnesota Mining And Manufacturing Company Low velocity aortic cannula
US5556390A (en) 1995-03-07 1996-09-17 Quinton Instrument Company Catheter with oval or elliptical lumens
EP0819014B1 (fr) * 1995-03-30 2003-02-05 Heartport, Inc. Catheter intravasculaire de decharge cardiaque
US6053900A (en) * 1996-02-16 2000-04-25 Brown; Joe E. Apparatus and method for delivering diagnostic and therapeutic agents intravascularly
US5868703A (en) 1996-04-10 1999-02-09 Endoscopic Technologies, Inc. Multichannel catheter
US5746709A (en) * 1996-04-25 1998-05-05 Medtronic, Inc. Intravascular pump and bypass assembly and method for using the same
US5688245A (en) * 1996-05-02 1997-11-18 Runge; Thomas M. Cannula system for a biventricular cardiac support system or a cardiopulmonary bypass system
US5965089A (en) * 1996-10-04 1999-10-12 United States Surgical Corporation Circulatory support system
US5776111A (en) 1996-11-07 1998-07-07 Medical Components, Inc. Multiple catheter assembly
US5807311A (en) 1996-11-29 1998-09-15 Palestrant; Aubrey M. Dialysis catheter having rigid and collapsible lumens and related method
US5795326A (en) 1997-01-29 1998-08-18 Baxter International Inc. Double lumen tubing design for catheter
US6532964B2 (en) 1997-07-11 2003-03-18 A-Med Systems, Inc. Pulmonary and circulatory blood flow support devices and methods for heart surgery procedures
US5947953A (en) * 1997-08-06 1999-09-07 Hemocleanse, Inc. Splittable multiple catheter assembly and methods of inserting the same
US6059760A (en) * 1997-08-14 2000-05-09 Medtronic, Inc. Cannula having reverse flow tip
US6371935B1 (en) * 1999-01-22 2002-04-16 Cardeon Corporation Aortic catheter with flow divider and methods for preventing cerebral embolization
US6889082B2 (en) * 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
UA56262C2 (uk) 1997-10-09 2003-05-15 Орквіс Медікел Корпорейшн Імплантовувана система підтримки серця
US6387037B1 (en) 1997-10-09 2002-05-14 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6610004B2 (en) 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6390969B1 (en) * 1997-10-09 2002-05-21 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6135981A (en) * 1997-10-22 2000-10-24 Dyke; Charles C. Protective aortic occlusion catheter
US5928181A (en) * 1997-11-21 1999-07-27 Advanced International Technologies, Inc. Cardiac bypass catheter system and method of use
US6044845A (en) * 1998-02-03 2000-04-04 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
CA2626830A1 (fr) 1998-02-24 1999-08-26 Boston Scientific Limited Catheters de dialyse a debit eleve et procedes de placement et de fabrication associes
US6508777B1 (en) * 1998-05-08 2003-01-21 Cardeon Corporation Circulatory support system and method of use for isolated segmental perfusion
US6083198A (en) * 1998-06-25 2000-07-04 Cardiovention, Inc. Perfusion catheter providing segmented flow regions and methods of use
US6293958B1 (en) * 1998-07-27 2001-09-25 Acist Medical Systems, Inc. Catheter having flow diffusing tip
US6167765B1 (en) * 1998-09-25 2001-01-02 The Regents Of The University Of Michigan System and method for determining the flow rate of blood in a vessel using doppler frequency signals
US7780628B1 (en) 1999-01-11 2010-08-24 Angiodynamics, Inc. Apparatus and methods for treating congestive heart disease
US6161547A (en) 1999-01-15 2000-12-19 Coaxia, Inc. Medical device for flow augmentation in patients with occlusive cerebrovascular disease and methods of use
US6743196B2 (en) 1999-03-01 2004-06-01 Coaxia, Inc. Partial aortic occlusion devices and methods for cerebral perfusion augmentation
US6409700B1 (en) * 1999-03-22 2002-06-25 Cfd Research Corporation Double lumen catheter
US6383172B1 (en) * 1999-04-02 2002-05-07 Coaxia, Inc. Retrograde venous perfusion with isolation of cerebral circulation
US6245045B1 (en) * 1999-04-23 2001-06-12 Alexander Andrew Stratienko Combination sheath and catheter for cardiovascular use
US6592567B1 (en) * 1999-12-07 2003-07-15 Chf Solutions, Inc. Kidney perfusion catheter
US6514226B1 (en) * 2000-02-10 2003-02-04 Chf Solutions, Inc. Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney
US6287608B1 (en) * 2000-04-11 2001-09-11 Intellicardia, Inc. Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney by infusion of a vasodilator
US6719749B1 (en) * 2000-06-01 2004-04-13 Medical Components, Inc. Multilumen catheter assembly and methods for making and inserting the same
US6488662B2 (en) 2000-12-19 2002-12-03 Laksen Sirimanne Percutaneous catheter assembly
US6761700B2 (en) 2001-02-09 2004-07-13 Orqis Medical Corporation Extra-corporeal vascular conduit
US7048680B2 (en) * 2001-06-06 2006-05-23 Orqis Medical Corporation Multilumen catheter for minimizing limb ischemia
US20020188167A1 (en) * 2001-06-06 2002-12-12 Anthony Viole Multilumen catheter for minimizing limb ischemia
US20050085683A1 (en) * 2003-10-15 2005-04-21 Bolling Steven F. Implantable heart assist system and method of applying same
US20050113631A1 (en) * 2003-11-12 2005-05-26 Bolling Steven F. Cannulae having a redirecting tip
US20050131385A1 (en) * 2003-12-12 2005-06-16 Bolling Steven F. Cannulae for selectively enhancing blood flow
US7445592B2 (en) * 2004-06-10 2008-11-04 Orqis Medical Corporation Cannulae having reduced flow resistance
US20050277804A1 (en) * 2004-06-10 2005-12-15 Robert Pecor System including a cannula having reduced flow resistance

Also Published As

Publication number Publication date
ATE400314T1 (de) 2008-07-15
US20020188166A1 (en) 2002-12-12
US20040138519A1 (en) 2004-07-15
AU2002214653B2 (en) 2006-04-13
US7048680B2 (en) 2006-05-23
DE60134790D1 (de) 2008-08-21
ES2307661T3 (es) 2008-12-01
WO2002098499A3 (fr) 2003-07-24
WO2002098499A2 (fr) 2002-12-12
US20060270891A1 (en) 2006-11-30
US20060270895A1 (en) 2006-11-30
EP1395324A2 (fr) 2004-03-10
CA2449689A1 (fr) 2002-12-12
AU2002214653C1 (en) 2006-12-14
JP2004528139A (ja) 2004-09-16

Similar Documents

Publication Publication Date Title
US7048680B2 (en) Multilumen catheter for minimizing limb ischemia
CA2480465C (fr) Catheter a lumieres multiples permettant de minimiser l'ischemie des membres
AU2002214653A1 (en) A multilumen catheter for minimizing limb ischemia
US8920404B2 (en) Reduction of recirculation in catheters
US7135008B2 (en) Method and apparatus for ultrafiltration utilizing a peripheral access dual lumen venous cannula
EP1898990B1 (fr) Pointe de securite pour catheter vasculaire
US20040215142A1 (en) Appliance for cannulation of a blood vessel
WO1999066977A1 (fr) Catheter de transfusion a regions de debit segmentees, et mode d'emploi
US20090216174A1 (en) Double lumen dialysis catheter with closeable arterial distal port
US20220273853A1 (en) Arrangement for Transporting a Liquid Through a Cannula System, Corresponding Kit and Method
US20190380563A1 (en) Introducer sheath having perfusion capabilities and methods of use
AU2008200502B2 (en) A Multilumen Catheter for Minimizing Limb Ischemia
AU2011202758A1 (en) A Multilumen Catheter for Minimizing Limb Ischemia
Ahmed ECMO Cannulation and Configuration

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20031218

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: O'LEARY, SEAN

Inventor name: VIOLE, ANTHONY

Inventor name: WARNER, WOLFGANG

Inventor name: SIRIMANNE, LAKSEN

Inventor name: BOLLING, STEVEN

17Q First examination report despatched

Effective date: 20050411

17Q First examination report despatched

Effective date: 20050411

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: KIRKER & CIE S.A.

Ref country code: CH

Ref legal event code: EP

REF Corresponds to:

Ref document number: 60134790

Country of ref document: DE

Date of ref document: 20080821

Kind code of ref document: P

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2307661

Country of ref document: ES

Kind code of ref document: T3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20081209

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081031

26N No opposition filed

Effective date: 20090414

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081015

REG Reference to a national code

Ref country code: GB

Ref legal event code: 732E

Free format text: REGISTERED BETWEEN 20100218 AND 20100224

REG Reference to a national code

Ref country code: FR

Ref legal event code: TP

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20081015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20080709

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20081010

REG Reference to a national code

Ref country code: ES

Ref legal event code: PC2A

Owner name: THORATEC CORPORATION

Effective date: 20110801

REG Reference to a national code

Ref country code: NL

Ref legal event code: SD

Effective date: 20110808

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: DR. JOACHIM LAUER PATENTANWALT

Ref country code: CH

Ref legal event code: PUE

Owner name: THORATEC CORPORATION

Free format text: ORQIS MEDICAL CORPORATION#20914 BAKE PARKWAY SUITE 112,#LAKE FOREST CALIFORNIA 92630 (US) -TRANSFER TO- THORATEC CORPORATION#6035 STONERIDGE DRIVE#PLEASANTON, CALIFORNIA 94588 (US)

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: RENTSCH PARTNER AG

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20121029

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20131029

Year of fee payment: 13

Ref country code: DE

Payment date: 20131029

Year of fee payment: 13

Ref country code: GB

Payment date: 20131028

Year of fee payment: 13

Ref country code: FR

Payment date: 20131017

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20131024

Year of fee payment: 13

Ref country code: ES

Payment date: 20131028

Year of fee payment: 13

Ref country code: NL

Payment date: 20131026

Year of fee payment: 13

REG Reference to a national code

Ref country code: SE

Ref legal event code: EUG

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20131016

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 60134790

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: V1

Effective date: 20150501

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20141015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141015

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150501

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20150630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150501

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141015

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20151127

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141016