EP1436410A4 - Essai d'antigene nucleocapsidique de virus de l'hepatite c (vhc) pour le criblage de composes antiviraux - Google Patents

Essai d'antigene nucleocapsidique de virus de l'hepatite c (vhc) pour le criblage de composes antiviraux

Info

Publication number
EP1436410A4
EP1436410A4 EP02773541A EP02773541A EP1436410A4 EP 1436410 A4 EP1436410 A4 EP 1436410A4 EP 02773541 A EP02773541 A EP 02773541A EP 02773541 A EP02773541 A EP 02773541A EP 1436410 A4 EP1436410 A4 EP 1436410A4
Authority
EP
European Patent Office
Prior art keywords
screening
core antigen
hcv core
viral compounds
antigen assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02773541A
Other languages
German (de)
English (en)
Other versions
EP1436410A1 (fr
Inventor
Laurence Gagnon
Chander Bahl
Stephen Lee
Patrick C Niven
Kenneth A Simmen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of EP1436410A1 publication Critical patent/EP1436410A1/fr
Publication of EP1436410A4 publication Critical patent/EP1436410A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP02773541A 2001-09-21 2002-09-23 Essai d'antigene nucleocapsidique de virus de l'hepatite c (vhc) pour le criblage de composes antiviraux Withdrawn EP1436410A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32422801P 2001-09-21 2001-09-21
US324228P 2001-09-21
PCT/US2002/030188 WO2003025210A1 (fr) 2001-09-21 2002-09-23 Essai d'antigene nucleocapsidique de virus de l'hepatite c (vhc) pour le criblage de composes antiviraux

Publications (2)

Publication Number Publication Date
EP1436410A1 EP1436410A1 (fr) 2004-07-14
EP1436410A4 true EP1436410A4 (fr) 2005-04-06

Family

ID=23262651

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02773541A Withdrawn EP1436410A4 (fr) 2001-09-21 2002-09-23 Essai d'antigene nucleocapsidique de virus de l'hepatite c (vhc) pour le criblage de composes antiviraux

Country Status (4)

Country Link
EP (1) EP1436410A4 (fr)
JP (1) JP2005524826A (fr)
CA (1) CA2461352A1 (fr)
WO (2) WO2003025209A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI294036B (en) * 2005-02-24 2008-03-01 Tzu Chi Buddhist General Hospital A method for screening compounds against flaviviruses infection by using persistent virus-infected cell systems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972828A1 (fr) * 1998-06-24 2000-01-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procés pour la réplication in vitro du HCV
EP1043399A2 (fr) * 1999-04-03 2000-10-11 Ralf Dr. Bartenschlager Système de culture du virus de l'hépatite C

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2283379A1 (fr) * 1997-03-05 1998-09-11 Michael G. Katze Nouveaux procedes de criblage permettant l'identification d'agents inhibant de maniere selective la replication du virus de l'hepatite c
US6447994B1 (en) * 2000-06-20 2002-09-10 The General Hospital Corporation Production of replicative hepatitis C virus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972828A1 (fr) * 1998-06-24 2000-01-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procés pour la réplication in vitro du HCV
EP1043399A2 (fr) * 1999-04-03 2000-10-11 Ralf Dr. Bartenschlager Système de culture du virus de l'hépatite C

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
HIRAMATSU N ET AL: "HCV CDNA TRANSFECTION TO HEPG2 CELLS", JOURNAL OF VIRAL HEPATITIS, BLACKWELL, OXFORD, GB, vol. 4, no. SUPPL 1, 1997, pages 61 - 67, XP008011131, ISSN: 1352-0504 *
LEE S R ET AL: "Efficacy of a hepatitis C virus core antigen enzyme-linked immunosorbent assay for the identification of 'window-phase' blood donations", VOX SANGUINIS, S. KARGER AG, BASEL, CH, vol. 80, January 2001 (2001-01-01), pages 19 - 23, XP002210662, ISSN: 0042-9007 *
MERCER D F ET AL: "Hepatitis C virus replication in mice with chimeric human livers", NATURE MEDICINE, NATURE PUBLISHING, CO, US, vol. 7, no. 8, August 2001 (2001-08-01), pages 927 - 933, XP002273301, ISSN: 1078-8956 *
MYUNG J ET AL: "Inducible model to study negative strand RNA synthesis and assembly of hepatitis C virus from a full-length cDNA clone", JOURNAL OF VIROLOGICAL METHODS, AMSTERDAM, NL, vol. 94, no. 1-2, May 2001 (2001-05-01), pages 55 - 67, XP002224466, ISSN: 0166-0934 *
See also references of WO03025210A1 *
TANAKA EIJI ET AL: "Evaluation of a new enzyme immunoassay for hepatitis C virus (HCV) core antigen with clinical sensitivity approximating that of genomic amplification of HCV RNA", HEPATOLOGY, vol. 32, no. 2, August 2000 (2000-08-01), pages 388 - 393, XP002315659, ISSN: 0270-9139 *
YOO ET AL: "Transfection of differentiated Huh7 with in vitro transcribed HCV RNA and establishment of a culture infected with HCV", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 69, no. 1, 1995, pages 32 - 38, XP002022696, ISSN: 0022-538X *

Also Published As

Publication number Publication date
EP1436410A1 (fr) 2004-07-14
WO2003025210A1 (fr) 2003-03-27
CA2461352A1 (fr) 2003-03-27
WO2003025209A1 (fr) 2003-03-27
JP2005524826A (ja) 2005-08-18

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Legal Events

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