EP1473145A2 - Procédé pour le pressage d'essai de comprimés - Google Patents

Procédé pour le pressage d'essai de comprimés Download PDF

Info

Publication number: EP1473145A2
Authority: EP; European Patent Office
Prior art keywords: rotor; filling; punches; dies; printing station
Prior art date: 2003-04-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP04008672A

Other languages

German (de)

English (en)

Other versions

EP1473145A3 (fr

EP1473145B1 (fr

Inventor

Jürgen Hinzpeter

Ingo Schmidt

Ulrich Gathmann

Jörg Gaedecke

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Fette GmbH

Original Assignee

Fette GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-28

Filing date

2004-04-10

Publication date

2004-11-03

2004-04-10 Application filed by Fette GmbH filed Critical Fette GmbH

2004-11-03 Publication of EP1473145A2 publication Critical patent/EP1473145A2/fr

2006-10-11 Publication of EP1473145A3 publication Critical patent/EP1473145A3/fr

2013-04-24 Application granted granted Critical

2013-04-24 Publication of EP1473145B1 publication Critical patent/EP1473145B1/fr

2024-04-10 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements

Definitions

the invention relates to a method for trial compression of tablets according to claim 1.
Tablets are usually made with rotary tablet presses or rotary tablet machines produced.
Such machines have a rotor, with a die plate, which has a number of dies, top and Lower stamps that work with the matrices and at least one Printing station in which the stamps are inserted into the matrices against the material the die are pressed. This happens during the rotation of the rotor is driven by a suitable drive device. Before pressing the matrices must be filled with the material to be pressed (powder). This happens continuously with the rotor rotating in a so-called filling shoe or a filling arrangement which is arranged stationary.
Press tests with a production rotary press naturally have the advantage that the data determined during pressing tests is transferred directly to production can be. In addition, all settings of the rotary press from the Press test for production use can be taken over.
the invention has for its object a method for test compression of To specify tablets that can be carried out on the one hand under production conditions and on the other hand manages with the least amount of molding material.
a conventional tabletting machine is used used, as is usually used in production.
one Rotary tableting companies can therefore use one Machine can be used according to the invention for experimental purposes.
This is done at at least partially removable filling arrangement and in a predetermined Filling position when the rotor is at least one die with molding material filled.
the filling process usually consists of the filling process and the Dosing process together.
a suitable control cam segment the lower punch, which is located within the die are moved down by a certain amount to a volume of Release the matrix for filling material. If this filling is done, will with a further cam segment a slight increase in Lower stamp causes.
the lifting takes place in an exact filling position, in the the volume specifies the filling quantity exactly.
the rotor is stopped in a position in which a lower stamp is in the filling position, d. H. the lower stamp gives exactly the filling volume in the die.
This position is not problematic with the help of the drive control, since it has long been known, the Rotation of the rotor with the help of suitable angle detection precautions monitor and control. Such monitoring is required if Press characteristics should be assigned to the individual pairs of punches.
Filling the single die can e.g. B. done by hand or with the help of a special filling device suitable for this.
the usual filling arrangement is removed or moved to the side so far that the filling of the single die is possible. It is understood that a limited number of matrices are included Press material can be filled. This then requires that the rotor step moves the associated dies to the filling position step by step.
the rotor After filling the die, the rotor is rotated and so far accelerates that it reaches the desired when it reaches the printing station Production speed or speed has reached. Instructs the printing station a pre-printing station, then the rotor must already be in the pre-printing station Show production speed. Often used in larger rotary tablet machines used three printing stations with three filling arrangements to press three tablets in parallel at the same time. In this case the rotor only has a relatively short distance to reach the Production speed available. This can be done with current drives realize.
All process-relevant settings can be made in the pressing test and be tried out, such as speed, pressing force, tablet thickness, tablet hardness, Tablet weight, etc.
To test the compressibility of new tablet forms only a pair of stamps are made. It is also possible to have a number of to test different stamp shapes, which are inserted in pairs in the rotor become. With a single revolution of the rotor, a plurality of different stamp shapes can be examined.
a rotor 10 of a rotary tablet machine is shown, the one
the die plate 12 has a series of dies 14 that form a circle are arranged around the axis of the rotor 10 with die bores 16 for Inclusion of material to be pressed.
Each die 14 or die hole 16 is assigned an upper stamp and lower stamp, which are not shown in FIG. 1 are shown.
a pre-printing station 18 and one Main printing station 20 arranged on the circumference of the rotor 10 . They have pairs of pressure rollers, one of which a lower pressure roller is shown at 22 and 24, respectively.
the pressure rollers work with the facing ends of the stamp together to insert them into the Press in die holes 16 and the material contained therein compress.
a filling arrangement 26 shown in the direction of rotation in front of the printing station 18 .
the details of the filling arrangement should not be discussed, since they are known.
the filling arrangement which has a certain volume has and a filling funnel is continuously filled, the matrices filled, which each run below the filling arrangement 26. At this The die bores gradually move with molding material refilled.
the tablets pressed in the main printing station 20 are made by ejected the lower stamps, while the upper stamps are above the Matrices.
a scraper (not shown) ensures that they become one Tablet outlet 28 are pushed.
Fig. 2 two upper stamps are shown at 30, while a series of Lower stamp 32 is drawn in dashed lines. It can be seen that the stamps 30, 32 move to the right from the printing station 18 and different positions take in height relative to the die plate 12. This is achieved through a Control curve 34 for the upper punch 30 and by a control curve 36 for the Lower stamp 32 for ejection. Following on from the main printing station 20 the filling, the filling arrangement 26 according to FIG. 1 not being shown in FIG. 2 or removed. The upper punches 30 have a raised position outside of the die hole, the top of those not shown in Fig. 2 Die plate is indicated by the dashed line 36a. The elongated Box 38 indicates the filling section and box 40 the dosing section.
the Filling arrangement 26 according to FIG. 1 has ceased to exist. Otherwise, the 3 have the same parts as in FIG. 1 in Fig. 3 the same parts with Fig. 1 provided with the same reference numerals.
the rotor 10 When a pressing test is carried out, the rotor 10 is brought into a position in which is a lower punch 32 in the filling position, as by 40 in Fig. 2nd indicated. Now, with the rotor 10 stationary, use a suitable one Filling device or by hand the die bore 16 filled with molding material.
the control for the drive of the rotor 10, not shown, is via a computer set so that the rotor automatically turns exactly one turn after the strength is rotated so that the working pair of punches is again in the filling position.
the acceleration of the rotor drive is set so that the Production speed is already reached in the pre-printing station 18 Avoid slope angles.
Suitable measuring points not shown, added. These include the Speed of rotation of the rotor 10 and the pressing characteristics in the pre and Main pressure station 18, 20 using suitable pressure or force transducers be measured.
the signals from the measuring points are recorded in the computer and brought to the display and evaluation. It can do this automatically several single tablets are pressed in succession, after each Revolution process and tablet parameters based on the measurement data or by predefined changes in the setting parameters are automatically adapted to determine optimal production conditions.
stamps 30, 32 can be installed stay or be expanded. As already mentioned, a single pair of stamps is sufficient to be able to carry out pressing tests. The installation of blind matrices in the Removal of ram is not necessary.
the data obtained in the pressing test can be easily applied to the Tableting machine can be transferred under production conditions.

Landscapes

Engineering & Computer Science (AREA)
Mechanical Engineering (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Medicinal Preparation (AREA)
Basic Packing Technique (AREA)

EP04008672.0A 2003-04-28 2004-04-10 Procédé pour le pressage d'essai de comprimés Expired - Lifetime EP1473145B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10319024A DE10319024B3 (de)	2003-04-28	2003-04-28	Verfahren zur Versuchspressung von Tabletten
DE10319024		2003-04-28

Publications (3)

Publication Number	Publication Date
EP1473145A2 true EP1473145A2 (fr)	2004-11-03
EP1473145A3 EP1473145A3 (fr)	2006-10-11
EP1473145B1 EP1473145B1 (fr)	2013-04-24

Family

ID=32695246

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP04008672.0A Expired - Lifetime EP1473145B1 (fr)	2003-04-28	2004-04-10	Procédé pour le pressage d'essai de comprimés

Country Status (3)

Country	Link
US (1)	US7032460B2 (fr)
EP (1)	EP1473145B1 (fr)
DE (1)	DE10319024B3 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102005007790B4 (de) *	2005-02-19	2007-06-28	Fette Gmbh	Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten
DE102005030312B4 (de) *	2005-06-23	2011-05-05	Korsch Ag	Rundläufer-Tablettiermaschine und Verfahren zur Herstellung einer Mehrschichttablette
DE102005030311B3 (de) *	2005-06-23	2006-11-23	Korsch Ag	Verfahren zur Pressung von Tabletten und Rundläufer- Tablettiermaschine
DE102007052552B4 (de) *	2007-10-29	2010-01-07	Luxner, Peter, Dipl.-Ing.	Verfahren und Vorrichtung zur Ermittlung von Steuer- und Regelparametern für Tablettenpressen
CN105289414A (zh) *	2015-11-13	2016-02-03	浙江中源电气成套技术有限公司	一种移动式生物质收集造粒系统
DE102023125660B3 (de)	2023-09-21	2025-02-13	Fette Compacting Gmbh	Verfahren zur Versuchspressung von Presslingen in einer Rundläuferpresse
DE102023127940B4 (de) *	2023-10-12	2025-08-14	Fette Compacting Gmbh	Verfahren zur Versuchspressung von Presslingen in einer Rundläuferpresse sowie Rundläuferpresse

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE569198A (fr) *	1957-07-12
DE2742572B1 (de) *	1977-09-22	1979-03-29	Fette Wilhelm Gmbh	Verfahren zum Herstellen von Tabletten und Tablettenpresse
FI92145C (fi) *	1993-01-28	1994-10-10	Tensor Oy	Menetelmä ja laitteisto tabletin puristamisen simuloimiseksi
JP2975346B1 (ja) *	1998-07-29	1999-11-10	株式会社菊水製作所	粉末圧縮成形機
US6830442B2 (en) *	2001-08-09	2004-12-14	William Alvin Cecil	Rotary tablet press

2003
- 2003-04-28 DE DE10319024A patent/DE10319024B3/de not_active Expired - Fee Related
2004
- 2004-04-10 EP EP04008672.0A patent/EP1473145B1/fr not_active Expired - Lifetime
- 2004-04-27 US US10/832,618 patent/US7032460B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE10319024B3 (de)	2004-08-12
US7032460B2 (en)	2006-04-25
US20040211265A1 (en)	2004-10-28
EP1473145A3 (fr)	2006-10-11
EP1473145B1 (fr)	2013-04-24

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