EP1476018A4 - Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines - Google Patents

Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines

Info

Publication number: EP1476018A4
Authority: EP; European Patent Office
Prior art keywords: glucosamidin; saponine; phosphate; compositions containing; containing aminoalkyl
Prior art date: 2002-02-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02706143A

Other languages

German (de)

English (en)

Other versions

EP1476018A1 (fr

Inventor

Sally Mossman

Lawrence Evans

Jory R Baldridge

Jay T Evans

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Corixa Corp

Agenus Inc

Original Assignee

Corixa Corp

Antigenics LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-04

Filing date

2002-02-04

Publication date

2005-09-21

2002-02-04 Application filed by Corixa Corp, Antigenics LLC filed Critical Corixa Corp

2004-11-17 Publication of EP1476018A1 publication Critical patent/EP1476018A1/fr

2005-09-21 Publication of EP1476018A4 publication Critical patent/EP1476018A4/fr

Status Withdrawn legal-status Critical Current

Links

229910019142 PO4 Inorganic materials 0.000 title 1
230000003308 immunostimulating effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1
SYXUBXTYGFJFEH-UHFFFAOYSA-N oat triterpenoid saponin Chemical compound CNC1=CC=CC=C1C(=O)OC1C(C=O)(C)CC2C3(C(O3)CC3C4(CCC5C(C)(CO)C(OC6C(C(O)C(OC7C(C(O)C(O)C(CO)O7)O)CO6)OC6C(C(O)C(O)C(CO)O6)O)CCC53C)C)C4(C)CC(O)C2(C)C1 SYXUBXTYGFJFEH-UHFFFAOYSA-N 0.000 title 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
239000010452 phosphate Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Immunology (AREA)
Pulmonology (AREA)
Biotechnology (AREA)
Mycology (AREA)
Microbiology (AREA)
Tropical Medicine & Parasitology (AREA)
Neurology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
AIDS & HIV (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)

EP02706143A 2002-02-04 2002-02-04 Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines Withdrawn EP1476018A4 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2002/003313 WO2003069997A1 (fr)	2002-02-04	2002-02-04	Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines

Publications (2)

Publication Number	Publication Date
EP1476018A1 EP1476018A1 (fr)	2004-11-17
EP1476018A4 true EP1476018A4 (fr)	2005-09-21

Family

ID=27752544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02706143A Withdrawn EP1476018A4 (fr)	2002-02-04	2002-02-04	Compositions immunostimulantes a base de phosphates d'aminoalkyl glucosaminide et de saponines

Country Status (5)

Country	Link
EP (1)	EP1476018A4 (fr)
JP (1)	JP2005525344A (fr)
AU (1)	AU2002240250A1 (fr)
CA (1)	CA2477191A1 (fr)
WO (1)	WO2003069997A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2009536653A (ja) *	2006-05-09	2009-10-15	ザヘンリーエム．ジャクソンファウンデーションフォーザアドヴァンスメントオブミリタリーメディシンインコーポレイテッド	Ｈｉｖ−１免疫原性組成物
WO2009080719A1 (fr) *	2007-12-21	2009-07-02	Glaxosmithkline Biologicals S.A.	Vaccin
CN110833555B (zh) *	2018-08-15	2023-03-24	广西梧州制药（集团）股份有限公司	吡唑并嘧啶衍生物在治疗溃疡性结肠炎的用途
SG11202106603UA (en) *	2018-12-21	2021-07-29	Sapreme Tech Bv	Biologically active cluster of molecules
CN110317794A (zh) *	2019-06-12	2019-10-11	吉林特研生物技术有限责任公司	一种重组杆状病毒、貉细小病毒重组亚单位疫苗及其制备方法
WO2021260054A2 (fr) *	2020-06-24	2021-12-30	Sapreme Technologies B.V.	Dérivés de saponine à fenêtre thérapeutique améliorée
CN118647385A (zh) *	2022-09-26	2024-09-13	林峙谙	包含类萜和大分子的新颖组合物及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20010053363A1 (en) *	2000-03-17	2001-12-20	Johnson David A.	Novel amphipathic aldehydes and their uses as adjuvants and immunoeffectors
WO2002003961A1 (fr) *	2000-07-07	2002-01-17	Corixa Corporation	Microspheres et adjuvants utilises pour l'administration de vaccins a base d'adn

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69828507T2 (de) *	1997-05-20	2006-01-05	Galenica Pharmaceuticals, Inc.	Triterpene-saponin analoga mit adjuvans und immunostimulierender wirkung

2002
- 2002-02-04 JP JP2003568973A patent/JP2005525344A/ja active Pending
- 2002-02-04 EP EP02706143A patent/EP1476018A4/fr not_active Withdrawn
- 2002-02-04 WO PCT/US2002/003313 patent/WO2003069997A1/fr not_active Ceased
- 2002-02-04 CA CA002477191A patent/CA2477191A1/fr not_active Abandoned
- 2002-02-04 AU AU2002240250A patent/AU2002240250A1/en not_active Abandoned

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20010053363A1 (en) *	2000-03-17	2001-12-20	Johnson David A.	Novel amphipathic aldehydes and their uses as adjuvants and immunoeffectors
WO2002003961A1 (fr) *	2000-07-07	2002-01-17	Corixa Corporation	Microspheres et adjuvants utilises pour l'administration de vaccins a base d'adn

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03069997A1 *

Also Published As

Publication number	Publication date
WO2003069997A1 (fr)	2003-08-28
JP2005525344A (ja)	2005-08-25
CA2477191A1 (fr)	2003-08-28
AU2002240250A1 (en)	2003-09-09
EP1476018A1 (fr)	2004-11-17

Legal Events

Date	Code	Title	Description
2004-10-01	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-11-17	17P	Request for examination filed	Effective date: 20040827
2004-11-17	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2004-11-17	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2005-01-19	RIN1	Information on inventor provided before grant (corrected)	Inventor name: EVANS, JAY, T. Inventor name: BALDRIDGE, JORY, R. Inventor name: EVANS, LAWRENCE Inventor name: MOSSMAN, SALLY
2005-09-21	A4	Supplementary search report drawn up and despatched	Effective date: 20050809
2007-03-02	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-04-04	18D	Application deemed to be withdrawn	Effective date: 20061010

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