EP1476172A1 - Verwendung eines biotechnologischen honig-ersatzes zur herstellung einer kosmetischen oder dermatologischen zusammensetzung - Google Patents

Verwendung eines biotechnologischen honig-ersatzes zur herstellung einer kosmetischen oder dermatologischen zusammensetzung

Info

Publication number
EP1476172A1
EP1476172A1 EP02704875A EP02704875A EP1476172A1 EP 1476172 A1 EP1476172 A1 EP 1476172A1 EP 02704875 A EP02704875 A EP 02704875A EP 02704875 A EP02704875 A EP 02704875A EP 1476172 A1 EP1476172 A1 EP 1476172A1
Authority
EP
European Patent Office
Prior art keywords
honey
composition
substitute
biotechnological
sugars
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02704875A
Other languages
English (en)
French (fr)
Inventor
Claude Dal Farra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vincience SA
Original Assignee
Societe dExtraction des Principes Actifs SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dExtraction des Principes Actifs SA filed Critical Societe dExtraction des Principes Actifs SA
Publication of EP1476172A1 publication Critical patent/EP1476172A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988—Honey; Royal jelly, Propolis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to the use in a cosmetic or dermatological composition, or for the preparation of such a composition, of an effective amount of a honey substitute obtained by cultivating microorganisms with sugars whose composition is close to that of honey; the honey substitute or the composition being intended to accelerate healing and to hydrate the skin.
  • honey was used not only as food, but also as medicine. Its development has long accompanied that of civilizations, because for thousands of years, honey was the only source of sweetness. The ancient Egyptians, but also the Assyrians, the Chinese, the Greeks and the Romans used honey for the treatment of wounds and stomach aches. More recently, the traditional therapeutic effects of honey have been studied. The anti-bacterial activities of honey have been confirmed, but also its action on wounds, ulcers and burns. Honey is a product of choice for many skin problems.
  • honey In cosmetics, honey is commonly used for its bactericidal and moisturizing properties and in the treatment of wounds. It is also used as a depigmenting or whitening agent for the treatment of pigmentary spots on the skin, acting directly on melanogenesis and as a kerat ⁇ lytic agent to improve the radiance of the skin tone and treat wrinkles.
  • the Applicant has unexpectedly found that certain microorganisms can, under certain conditions, provide a biotechnological substitute for honey, and that the application of an effective amount of such a biotechnological substitute for honey makes it possible to accelerate the healing.
  • the present invention therefore relates to the use in a cosmetic or dermatological composition, or for the preparation of such a composition, of an effective amount of a biotechnological substitute for honey obtained by cultivating microorganisms with sugars of which the composition is close to that of honey; the substitute or the composition being intended to accelerate the healing.
  • the present invention also relates to the use in a cosmetic or dermatological composition, or for the preparation of such a composition, of an effective amount of a biotechnological substitute for honey obtained by cultivating microorganisms with sugars of which the composition is close to that of honey; the substitute or the composition being intended for skin hydration.
  • biotechnological honey substitute must be understood by “biotechnological honey substitute”.
  • honey substitute the applicant understands a compound rich in sugars, which has the properties attributed to honey in terms of soothing and healing.
  • biotechnological origin means obtained using microorganisms.
  • honey has certain anti-bacterial properties.
  • honey has certain anti-bacterial properties.
  • the Applicant has selected natural microorganisms, close to those naturally present in honey, and whose growth is not inhibited by honey. It therefore becomes possible to cultivate, under certain conditions, these microorganisms with honey, or a product close to honey, and then to extract the intra-cytoplasmic and extra-cytoplasmic content of the microorganisms thus cultivated.
  • the biotechnological honey substitute thus obtained contains:
  • biotechnological substitute for honey is obtained by cultivating microorganisms with sugars whose composition is close to that of honey.
  • the microorganism used is a yeast and preferably the microorganism used is Saccharomyces sp.
  • sugars whose composition is close to that of honey is meant a mixture of commercial sugars present in honey in their natural state.
  • these sugars those present mainly in honey are: a mixture of glucose and levulose (fructose) representing approximately 70% to 75% of honey, but also dextrin and sucrose representing respectively 10% and 2.5% of honey .
  • the distribution between the different sugars does not influence the use of the product, but preferably glucose and levulose are predominant compared to the other sugars.
  • the biotechnological substitute for honey is obtained by cultivating microorganisms with sugars which are a mixture of glucose, levulose, dextrins and sucrose.
  • the biotechnological substitute for honey is obtained by cultivating microorganisms with sugars used in an amount representing from 1% to 20% of the culture medium of the microorganism and preferably the sugars are used in an amount representing from 6% to 14% of the culture medium of the microorganism.
  • biotechnological substitute for honey contains from 10% to 50% of a glycol, and preferably the glycol used is hexylene glycol.
  • compositions according to the present invention will be in a dosage form suitable for administration by the topical skin route, and cover all cosmetic or dermatological forms.
  • These compositions must therefore contain a cosmetically and / or dermatologically acceptable medium, that is to say compatible with the skin, body hair or hair.
  • These compositions may in particular be in the form of creams, oil-in-water emulsions, water-in-oil or multiple emulsions, solutions, suspensions, or even powders, suitable for application to the skin, the lips and / or the hair. .
  • This composition may be more or less fluid and have the appearance of a cream, a lotion, a milk, a serum, an ointment, a gel, a paste or a foam. It can also be in solid form, like a stick, or be applied to the skin in the form of an aerosol. It can be used as a care product and / or as a skin makeup product.
  • compositions comprise, in a known manner, the adjuvants necessary for their formulation, such as solvents, thickeners, diluents, antioxidants, dyes, filters, pigments, fillers, preservatives, perfumes, odor absorbers.
  • these adjuvants as well as their proportions, will be chosen so as not to harm the properties sought in the invention.
  • These adjuvants can for example correspond to 0.01 to 20% of the total weight of the composition.
  • the fatty phase can represent from 5 to 80% by weight, and preferably from 5 to 50% by weight relative to the total weight of the composition.
  • the emulsifiers and coemulsifiers used in the composition will be chosen from those conventionally used in the field under consideration. For example, they can be used in a proportion ranging from 0.3 to 30% by weight, relative to the total weight of the composition.
  • biotechnological honey substitute as defined above, in an amount representing from 0.01% to 20% of the total weight of the composition and preferably in an amount representing from 0.1% to 10% of the total weight of the composition.
  • another subject of the invention consists of a cosmetic or dermatological composition containing, in a cosmetically or dermatologically acceptable medium, a biotechnological substitute for honey obtained by cultivating microorganisms with sugars whose composition is close to that of honey.
  • the biotechnological honey substitute is present in an amount ranging from 0.01% to 20% of the total weight of the composition, and preferably in an amount ranging from 0.1% to 10% by weight total of the composition.
  • the invention also relates to a cosmetic process which facilitates the healing of the skin, and which consists in applying the composition as defined above to scarified skin.
  • the invention finally relates to a cosmetic method for moisturizing the skin, consisting in applying the composition as defined above to the skin.
  • the microorganism used is a yeast.
  • the microorganism used is Saccharomyces sp. and preferably Saccharomyces cerevisiae. Saccharomyces cerevisiae yeasts are cultivated in a defined suitable medium.
  • the yeasts When the yeast concentration is high, the yeasts are concentrated by centrifugation, then returned to culture in an essentially aqueous liquid medium, with a high concentration of sugars.
  • a wet pellet of 150 grams of yeast is cultivated in a liter of an essentially aqueous medium for 18 to 36 hours containing 60 g / l of glucose, 65 g / l of levulose, 10 g / l of dextrin and 5 g 1 of sucrose.
  • 20% hexylene glycol can be added to the extract.
  • the extract is then treated and sterilized to comply with cosmetic requirements (color, odor, appearance, sterility ).
  • the product obtained is the biotechnological substitute for honey.
  • Example 2 Effect of the Biotechnological Substitute of Example 1 on Healing
  • the stretching is 28.7 mm + or - 2.2 mm.
  • the stretch is 23.2 mm + or - 1.6 mm.
  • the honey substitute of Example 1 has a healing power, a power which has been demonstrated on the one hand visually, on the other hand with stretching with a dynamometer.
  • compositions were obtained by simple mixing of the various components.
  • the quantities indicated are given as a percentage by weight.
  • Aqueous phase a Glycerin 5.00% a Allantoin 0.10% a Biotechnological substitute from Example 1 5.00% a Sepigel 305 (Polyacrylamide and C13-14 Isoparaffin and Laureth-7) 0.30% a Preservative 0, 50% a Perfume 0.50%
  • a Carbopol Ultrez lO (2% sol.) 25.00% a Triethanolamine 0.50% a Biotechnology substitute from Example 1 3.00% a Preservative 0.20% a EDTA (sequestering) 0.10% a Perfume 0.50% a Water qs 100%
  • a Mono Propylene Glycol 1.00% a Allantoin 0.30% a Glycerin 1.00% a Cetiol HE (PEG-7 Glyceryl Cocoate) 1.00% a Biotechnology substitute of example 1 1.00% a Preservative 0, 20% a Perfume 0.50% a Water qs 100%

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
EP02704875A 2002-02-21 2002-02-21 Verwendung eines biotechnologischen honig-ersatzes zur herstellung einer kosmetischen oder dermatologischen zusammensetzung Withdrawn EP1476172A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FR2002/000653 WO2003077934A1 (fr) 2002-02-21 2002-02-21 Utilisation d'un substitut biotechnologique de miel dans une composition cosmetique ou dermatologique

Publications (1)

Publication Number Publication Date
EP1476172A1 true EP1476172A1 (de) 2004-11-17

Family

ID=27839167

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02704875A Withdrawn EP1476172A1 (de) 2002-02-21 2002-02-21 Verwendung eines biotechnologischen honig-ersatzes zur herstellung einer kosmetischen oder dermatologischen zusammensetzung

Country Status (3)

Country Link
EP (1) EP1476172A1 (de)
AU (1) AU2002238681A1 (de)
WO (1) WO2003077934A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2957252B1 (fr) * 2010-03-09 2016-04-08 Lvmh Rech Composition cosmetique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1155422B (it) * 1982-12-10 1987-01-28 Dox Al Italia Spa Procedimento per la preparazione di una coltura integrale di cellule di saccharomyces cerevisiae
DE3721190C1 (de) * 1987-06-26 1989-02-02 Heyl Chem Pharm Kosmetisches Mittel
FR2696932B1 (fr) * 1992-10-19 1994-11-25 Sederma Sa Nouvelles compositions à usage cosmétique consistant de l'association d'un filtrat de fermentation et d'extraits de plantes.
US5840309A (en) * 1994-10-03 1998-11-24 La Prairie Sa Stimulating fibroblasts and/or keratinocytes
US5900226A (en) * 1997-04-09 1999-05-04 Uop Llc Drying agents for non-foamed polyurethanes
FR2751537B1 (fr) * 1996-07-26 2004-04-16 Oreal Utilisation du miel comme agent keratolytique, notamment pour ameliorer l'eclat du teint de la peau et traiter les rides
FR2818146B1 (fr) * 2000-12-20 2003-03-07 Seporga Substitut biotechnologique de miel et son utilisation dans une composition cosmetique ou dermatologique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO03077934A1 *

Also Published As

Publication number Publication date
WO2003077934A1 (fr) 2003-09-25
AU2002238681A1 (en) 2003-09-29

Similar Documents

Publication Publication Date Title
CA2201163C (fr) Utilisation d'un extrait d'au moins une iridacee dans le traitement des rides
EP0709084B1 (de) Verwendung eines an Petroselinsäurereichen Öls als Feuchthaltemittel
FR2671487A1 (fr) Utilisation d'un facteur de croissance dans une composition amincissante.
EP1278532B1 (de) Extrakt aus einer pflanze der spezies olea europaea als inhibitor der no-synthase und verwendungen
FR2557452A1 (fr) Nouvelles compositions pour les soins de la peau renfermant de l'huile d'onagre et des traits tissulaires de rate
EP0779071A1 (de) Stabile W/Ö/W-Emulsion, die einen wasserempfindlichen kosmetischen und/oder dermatologischen Wirkstoff enthält
EP0820765A2 (de) Verwendung von Honig als keratolytischen Agentien
EP0755672A1 (de) Silizium-Zusammensetzung, die ein wasserempfindliche Wirkstoff enthält
CA2134623A1 (fr) Emulsion eau-dans-huile contenant des polyols et son utilisation en cosmetologie
CA2407311A1 (fr) Extrait de vegetal de l'espece vitis vinifera comme inhibiteur de no-synthase et utilisations
CA2407334A1 (fr) Lipochroman-6 comme inhibiteur de no-synthase et utilisations
EP1147765A1 (de) Neuer Actif, sowie ihre Zusammensetzungen , ihre Verwendung in der Kosmetik, Dermokosmetik , Dermopharmacy, Pharmacy und auf Vliesstoffe
EP2291173A2 (de) Kombination von passionsblumen- und alkaner-extrakten zur verwendung in kosmetika
EP1768684B1 (de) Zusammensetzung enthaltend extrakte von blauem lotus zur behandlung von unkontrollierten gesichtsmuskelkontraktionen
WO2003077934A1 (fr) Utilisation d'un substitut biotechnologique de miel dans une composition cosmetique ou dermatologique
FR2818146A1 (fr) Substitut biotechnologique de miel et son utilisation dans une composition cosmetique ou dermatologique
FR2838962A1 (fr) Composition cosmetique comprenant un extrait de lentilles d'eau riche en apiose, procedes de traitement et utilisations
KR101993324B1 (ko) 피부 장벽 개선용 화장료 조성물
EP2699227A2 (de) Pflanzenextraktkomplex zum schutz der haut
CA2278226A1 (fr) Produits cosmetiques ou dermo-pharmaceutiques respectant l'ecologie cutanee
EP1155685B1 (de) Zusammensetzung enthaltend Mangan
FR2828098A1 (fr) Utilisation d'un substitut biotechnologique de miel comme agent anti-inflammatoire
FR3139466A1 (fr) Utilisation d’un extrait de poivrier de Sichuan pour un traitement cutané et une composition adaptée à cette utilisation.
FR3047667B1 (fr) Nouvelle composition cosmetique ou dermatologique pour le traitement des rougeurs
FR2871380A1 (fr) Composition comprenant un extrait vegetal a effet decontractant de la peau

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040906

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: RO

17Q First examination report despatched

Effective date: 20080312

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080723