EP1487965A4 - Minizellzusammensetzungen und -verfahren - Google Patents

Minizellzusammensetzungen und -verfahren

Info

Publication number
EP1487965A4
EP1487965A4 EP02747872A EP02747872A EP1487965A4 EP 1487965 A4 EP1487965 A4 EP 1487965A4 EP 02747872 A EP02747872 A EP 02747872A EP 02747872 A EP02747872 A EP 02747872A EP 1487965 A4 EP1487965 A4 EP 1487965A4
Authority
EP
European Patent Office
Prior art keywords
methods
minicell compositions
minicell
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02747872A
Other languages
English (en)
French (fr)
Other versions
EP1487965A2 (de
Inventor
Roger A Sabbadini
Mark Surber
Neil Berkley
Matthew Giacalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vaxiion Therapeutics LLC
Original Assignee
Mpex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27767433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1487965(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/154,951 external-priority patent/US20030194798A1/en
Application filed by Mpex Pharmaceuticals Inc filed Critical Mpex Pharmaceuticals Inc
Priority to EP20110000796 priority Critical patent/EP2390308A1/de
Priority to EP10008869.9A priority patent/EP2272946B9/de
Publication of EP1487965A2 publication Critical patent/EP1487965A2/de
Publication of EP1487965A4 publication Critical patent/EP1487965A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432Liposomes or microcapsules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP02747872A 2002-02-25 2002-05-28 Minizellzusammensetzungen und -verfahren Withdrawn EP1487965A4 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20110000796 EP2390308A1 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren
EP10008869.9A EP2272946B9 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US154951 1988-02-10
US35984302P 2002-02-25 2002-02-25
US359843P 2002-02-25
US10/154,951 US20030194798A1 (en) 2001-05-24 2002-05-24 Minicell compositions and methods
PCT/US2002/016877 WO2003072014A2 (en) 2002-02-25 2002-05-28 Minicell compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP10008869.9A Division EP2272946B9 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren

Publications (2)

Publication Number Publication Date
EP1487965A2 EP1487965A2 (de) 2004-12-22
EP1487965A4 true EP1487965A4 (de) 2006-11-15

Family

ID=27767433

Family Applications (3)

Application Number Title Priority Date Filing Date
EP10008869.9A Revoked EP2272946B9 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren
EP02747872A Withdrawn EP1487965A4 (de) 2002-02-25 2002-05-28 Minizellzusammensetzungen und -verfahren
EP20110000796 Withdrawn EP2390308A1 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP10008869.9A Revoked EP2272946B9 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP20110000796 Withdrawn EP2390308A1 (de) 2002-02-25 2002-05-28 Minizell-Zusammensetzungen und Verfahren

Country Status (5)

Country Link
EP (3) EP2272946B9 (de)
AU (1) AU2002318168B2 (de)
CA (1) CA2517027A1 (de)
ES (1) ES2541351T3 (de)
WO (1) WO2003072014A2 (de)

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US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
JP4458846B2 (ja) * 2001-10-15 2010-04-28 エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド invitroおよびinvivoにおけるDNA導入および遺伝子療法のためのベクターとしての完全なミニ細胞
US7561919B2 (en) 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
US7611885B2 (en) 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
DK1694361T3 (da) 2003-12-09 2011-06-06 Engeneic Molecular Delivery Pty Ltd Målrettet levering til ikke-phagocytiske pattedyrceller via bakterielt afledte intakte miniceller
DK2992901T3 (da) * 2004-02-02 2020-01-27 Engeneic Molecular Delivery Pty Ltd Sammensætninger og fremgangsmåder til målrettet in vitro- og in vivo-medicinlevering til pattedyrceller via bakterielt afledte intakte miniceller
US8772013B2 (en) 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
JP4114075B2 (ja) * 2004-02-16 2008-07-09 ヒューマン・メタボローム・テクノロジーズ株式会社 遺伝子産物の機能同定方法及び結合物質同定方法
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
WO2006055024A2 (en) * 2004-04-05 2006-05-26 Vaxiion Therapeutics, Inc. Minicells as vaccines
HUE024999T2 (en) 2004-08-26 2016-02-29 Engeneic Molecular Delivery Pty Ltd Introducing functional nucleic acids into mammalian cells with bacterial intact minicells
US9878043B2 (en) 2006-06-23 2018-01-30 Engeneic Molecular Delivery Pty Ltd Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
CA2827443C (en) 2011-02-15 2021-07-06 Vaxiion Therapeutics, Inc. Therapeutic compositions and methods for antibody and fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells
US20140342932A1 (en) * 2011-09-23 2014-11-20 Merck Sharp & Dohme Corp. Functional cell surface display of ligands for the insulin and/or insulin growth factor 1 receptor and applications thereof
EP2878335B1 (de) 2013-11-10 2018-01-03 Brainsgate Ltd. Implantat und implantationssystem für nervenstimulator
RU2577138C1 (ru) * 2014-11-25 2016-03-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения рекомбинантного белка sav-rgd
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
WO2018201160A1 (en) 2017-04-28 2018-11-01 Agrospheres, Inc. Compositions and methods for enzyme immobilization
EP3615659A4 (de) * 2017-04-28 2021-01-06 Agrospheres, Inc. Zusammensetzungen und verfahren zur verkapselung und skalierbaren abgabe von agrochemikalien
CA3073449A1 (en) 2017-09-25 2019-03-28 Agrospheres, Inc. Compositions and methods for scalable production and delivery of biologicals
KR20210069659A (ko) 2018-09-28 2021-06-11 스미또모 가가꾸 가부시키가이샤 미생물 분해 세균, 미생물 제제, 미생물의 분해 방법 및 분해 장치
AU2020205040A1 (en) 2019-01-04 2021-08-12 Engeneic Molecular Delivery Pty Ltd Encapsulated glycolipid antigens for treatment of neoplastic diseases
CN110669811A (zh) * 2019-10-21 2020-01-10 天津大学 一种提高表面活性素产量的方法
CN115551525A (zh) * 2020-03-06 2022-12-30 安度利体技术公司 用于治疗细胞内细菌感染的组合物和方法
CN116590372A (zh) * 2022-06-01 2023-08-15 上海中翊日化有限公司 一种嗜热栖热菌和纳豆芽孢杆菌组合发酵产物及其在化妆品中的应用
CN116087504B (zh) * 2023-02-24 2023-08-15 上海碧云天生物技术有限公司 免疫磁珠保护液、其制备方法及应用
CN119689002B (zh) * 2025-02-25 2025-06-06 山东大学 用于预测胚胎反复种植失败的生物标志物组合、试剂盒及其应用和联合药物及其应用

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WO2003072014A3 (en) 2004-02-12
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EP2272946B1 (de) 2015-04-08
EP1487965A2 (de) 2004-12-22
EP2272946B9 (de) 2015-06-24
EP2390308A1 (de) 2011-11-30
EP2272946A2 (de) 2011-01-12
AU2002318168B2 (en) 2007-12-13
AU2002318168A1 (en) 2003-09-09
EP2272946A3 (de) 2011-07-27
ES2541351T3 (es) 2015-07-17
HK1153229A1 (en) 2012-03-23
WO2003072014B1 (en) 2004-04-22

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