EP1501917A4 - Dispositif et procede d'imagerie de cellules analytiques - Google Patents

Dispositif et procede d'imagerie de cellules analytiques

Info

Publication number
EP1501917A4
EP1501917A4 EP03728685A EP03728685A EP1501917A4 EP 1501917 A4 EP1501917 A4 EP 1501917A4 EP 03728685 A EP03728685 A EP 03728685A EP 03728685 A EP03728685 A EP 03728685A EP 1501917 A4 EP1501917 A4 EP 1501917A4
Authority
EP
European Patent Office
Prior art keywords
analytical cells
imaging analytical
imaging
cells
analytical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03728685A
Other languages
German (de)
English (en)
Other versions
EP1501917A2 (fr
Inventor
Michael Trainer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunivest Corp
Original Assignee
Immunivest Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunivest Corp filed Critical Immunivest Corp
Publication of EP1501917A2 publication Critical patent/EP1501917A2/fr
Publication of EP1501917A4 publication Critical patent/EP1501917A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP03728685A 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques Withdrawn EP1501917A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37786802P 2002-05-03 2002-05-03
US377868P 2002-05-03
PCT/US2003/013842 WO2003093795A2 (fr) 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques

Publications (2)

Publication Number Publication Date
EP1501917A2 EP1501917A2 (fr) 2005-02-02
EP1501917A4 true EP1501917A4 (fr) 2006-04-19

Family

ID=29401578

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03728685A Withdrawn EP1501917A4 (fr) 2002-05-03 2003-05-05 Dispositif et procede d'imagerie de cellules analytiques

Country Status (5)

Country Link
EP (1) EP1501917A4 (fr)
JP (1) JP2005524833A (fr)
AU (1) AU2003234459A1 (fr)
CA (1) CA2484730A1 (fr)
WO (1) WO2003093795A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2500392C (fr) 2002-09-27 2012-11-27 The General Hospital Corporation Dispositif microfluidique pour la separation de cellules et utilisations de ce dispositif
JP4041458B2 (ja) * 2003-12-12 2008-01-30 日立ソフトウエアエンジニアリング株式会社 蛍光ビーズ検出方法及び蛍光ビーズ検出装置
WO2006017811A2 (fr) 2004-08-06 2006-02-16 Compucyte Corporation Absorption de lumiere monochromatique a couleurs multiples et quantification d'absorption de lumiere dans un echantillon colore
US20080201081A1 (en) * 2004-10-22 2008-08-21 Fermiscan Australia Pty Ltd Analytical Method and Apparatus
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
ES2886923T3 (es) 2005-09-20 2021-12-21 Menarini Silicon Biosystems Spa Métodos y composición para generar sondas de ADN de secuencia única, marcaje de sondas de ADN y el uso de estas sondas
US9134237B2 (en) 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
FI20051329A0 (fi) 2005-12-27 2005-12-27 Wallac Oy Laitteisto ja menetelmä näytteiden optista mittausta varten
WO2007133465A2 (fr) * 2006-05-12 2007-11-22 Immunivest Corporation Système d'éclairage laser en microscopie fluorescente
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2007147074A2 (fr) 2006-06-14 2007-12-21 Living Microsystems, Inc. Utilisation de génotypage snp fortement parallèle pour diagnostic fœtal
EP2589668A1 (fr) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse de cellules rares utilisant la division d'échantillons et les marqueurs d'ADN
WO2008012724A2 (fr) * 2006-07-20 2008-01-31 Koninklijke Philips Electronics N.V. Suivi optique et détermination de position pour procédés et systèmes de détection
US7782452B2 (en) * 2007-08-31 2010-08-24 Kla-Tencor Technologies Corp. Systems and method for simultaneously inspecting a specimen with two distinct channels
US8143600B2 (en) * 2008-02-18 2012-03-27 Visiongate, Inc. 3D imaging of live cells with ultraviolet radiation
HUE031848T2 (en) 2008-09-20 2017-08-28 Univ Leland Stanford Junior Non-invasive diagnosis of fetal aneuploidy by sequencing
JP5119114B2 (ja) * 2008-09-30 2013-01-16 富士フイルム株式会社 光源装置及び撮影装置
WO2011121751A1 (fr) * 2010-03-31 2011-10-06 古河電気工業株式会社 Dispositif de discrimination cellulaire et procédé de discrimination cellulaire
EP2689254A4 (fr) 2011-03-24 2014-09-03 Anpac Bio Medical Science Co Ltd Micro-dispositifs pour la détection d'une maladie
EP2707719A4 (fr) 2011-05-05 2015-05-13 Anpac Bio Medical Science Co Ltd Appareil de détection de cellules tumorales
JP2014523533A (ja) * 2011-07-07 2014-09-11 スクリップス ヘルス 心血管障害を分析する方法及びその用途
US9511152B2 (en) * 2012-04-05 2016-12-06 The Board Of Regents Of The University Of Texas System Multicolored pH-activatable fluorescence nanoplatform
CN104914078A (zh) * 2015-04-16 2015-09-16 南京昊控软件技术有限公司 一种大范围多点流体浓度测量系统
CA3220119A1 (fr) 2016-03-07 2017-09-14 X-Zell Inc. Compositions et procedes d'identification de cellules rares
FR3051556A1 (fr) * 2016-05-18 2017-11-24 Biocytex Utilisation de marqueurs fluorescents pour la detection de cible biologique dans un echantillon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034613A (en) * 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5127730A (en) * 1990-08-10 1992-07-07 Regents Of The University Of Minnesota Multi-color laser scanning confocal imaging system
US5698397A (en) * 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
JP3343276B2 (ja) * 1993-04-15 2002-11-11 興和株式会社 レーザー走査型光学顕微鏡
US5479252A (en) * 1993-06-17 1995-12-26 Ultrapointe Corporation Laser imaging system for inspection and analysis of sub-micron particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KAGAN M ET AL: "CellTracks Cell Analysis System for Rare Cell Detection", PROC. SPIE, CONF. CLINICAL DIAGNOSTIC SYSTEMS: TECHNOLOGIES AND INSTRUMENTATION, 22-24 JAN. 2002, SAN JOSE, CA, USA, vol. 4625, June 2002 (2002-06-01), pages 20 - 28, XP002368763 *
TIBBE A G J ET AL: "Imaging Technique Implemented in CellTracks System", CYTOMETRY, vol. 47, 1 April 2002 (2002-04-01), published online 21 March 2002, pages 248 - 255, XP002368764 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities

Also Published As

Publication number Publication date
EP1501917A2 (fr) 2005-02-02
JP2005524833A (ja) 2005-08-18
WO2003093795A3 (fr) 2004-10-21
AU2003234459A8 (en) 2003-11-17
WO2003093795A2 (fr) 2003-11-13
CA2484730A1 (fr) 2003-11-13
AU2003234459A1 (en) 2003-11-17

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