EP1503739A4 - Verzögerte freisetzung von guaifenesin-kombinationsprodukten - Google Patents
Verzögerte freisetzung von guaifenesin-kombinationsproduktenInfo
- Publication number
- EP1503739A4 EP1503739A4 EP03736462A EP03736462A EP1503739A4 EP 1503739 A4 EP1503739 A4 EP 1503739A4 EP 03736462 A EP03736462 A EP 03736462A EP 03736462 A EP03736462 A EP 03736462A EP 1503739 A4 EP1503739 A4 EP 1503739A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- sustained release
- combination drugs
- guaifenesin
- guaifenesin combination
- drugs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 title 1
- 229940000425 combination drug Drugs 0.000 title 1
- 229960002146 guaifenesin Drugs 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US121706 | 1998-07-24 | ||
| US10/121,706 US6955821B2 (en) | 2000-04-28 | 2002-04-15 | Sustained release formulations of guaifenesin and additional drug ingredients |
| US406574 | 2003-04-04 | ||
| US10/406,557 US7838032B2 (en) | 2000-04-28 | 2003-04-04 | Sustained release of guaifenesin |
| US10/406,574 US7985420B2 (en) | 2000-04-28 | 2003-04-04 | Sustained release of guaifenesin combination drugs |
| US406557 | 2003-04-04 | ||
| PCT/US2003/011500 WO2003088952A1 (en) | 2002-04-15 | 2003-04-15 | Sustained release of guaifenesin combination drugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1503739A1 EP1503739A1 (de) | 2005-02-09 |
| EP1503739A4 true EP1503739A4 (de) | 2006-06-21 |
Family
ID=29255202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03736462A Ceased EP1503739A4 (de) | 2002-04-15 | 2003-04-15 | Verzögerte freisetzung von guaifenesin-kombinationsprodukten |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1503739A4 (de) |
| JP (1) | JP5466346B2 (de) |
| CN (1) | CN1655766B (de) |
| AU (1) | AU2003237807B2 (de) |
| CA (1) | CA2481739C (de) |
| EA (1) | EA007156B1 (de) |
| IL (1) | IL164438A0 (de) |
| MX (1) | MXPA04010225A (de) |
| WO (1) | WO2003088952A1 (de) |
| ZA (1) | ZA200409171B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY142204A (en) | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
| KR20060076319A (ko) * | 2003-09-24 | 2006-07-04 | 콤비네이토릭스, 인코포레이티드 | 약물 조합들을 투여하는 치료 요법 |
| CA2476101A1 (en) * | 2004-08-12 | 2006-02-12 | Bernard Charles Sherman | Extended-release capsules comprising venlafaxine hydrochloride |
| NZ553587A (en) * | 2004-08-13 | 2010-12-24 | Boehringer Ingelheim Int | Extended release tablet formulation containing pramipexole or a pharmacutically acceptable salt thereof |
| CN103214484B (zh) | 2005-12-13 | 2016-07-06 | 因塞特控股公司 | 作为两面神激酶抑制剂的杂芳基取代的吡咯并[2,3-b]吡啶和吡咯并[2,3-b]嘧啶 |
| CN1994285B (zh) * | 2006-01-04 | 2011-03-16 | 上海医药工业研究院 | 愈创木酚甘油醚缓释微丸及其制备方法 |
| US20080176955A1 (en) * | 2007-01-16 | 2008-07-24 | Victory Pharma, Inc. | Combined administration of benzonatate and guaifenesin |
| CN101658507B (zh) * | 2008-08-26 | 2011-12-07 | 北京科信必成医药科技发展有限公司 | 一种愈创木酚甘油醚和伪麻黄碱的复方缓释制剂 |
| SG173528A1 (en) | 2009-02-04 | 2011-09-29 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
| EP3354652B1 (de) | 2010-03-10 | 2020-05-06 | Incyte Holdings Corporation | Piperidin-4-yl azetidin-derivate als jak1-inhibitoren |
| US9339478B2 (en) | 2011-02-04 | 2016-05-17 | Reckitt Benckiser Llc | Pharmaceutical formulation |
| MY165963A (en) | 2011-06-20 | 2018-05-18 | Incyte Holdings Corp | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors |
| CN102755304A (zh) * | 2012-08-03 | 2012-10-31 | 四川百利药业有限责任公司 | 一种愈美胶囊的制备方法 |
| TWI761825B (zh) | 2012-11-15 | 2022-04-21 | 美商英塞特控股公司 | 盧梭利替尼之緩釋性劑型 |
| SG11201600815WA (en) | 2013-08-07 | 2016-03-30 | Incyte Corp | Sustained release dosage forms for a jak1 inhibitor |
| GB201506755D0 (en) | 2015-04-21 | 2015-06-03 | Reckitt Benckiser Llc | Novel pharmaceutical formulation |
| CN105982860B (zh) * | 2015-02-11 | 2020-04-14 | 北京科信必成医药科技发展有限公司 | 愈创甘油醚无水吞服掩味颗粒 |
| US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| EP0384514A2 (de) * | 1989-02-21 | 1990-08-29 | Norwich Eaton Pharmaceuticals, Inc. | Tablette mit Doppelwirkung |
| WO2000033818A1 (en) * | 1998-12-11 | 2000-06-15 | Nostrum Pharmaceuticals, Inc. | Sustained release tablet containing hydrocolloid and cellulose ether |
| WO2001019901A2 (en) * | 1999-09-14 | 2001-03-22 | Smithkline Beecham Corporation | Process for making aqueous coated beadlets |
| US20020022058A1 (en) * | 2000-07-08 | 2002-02-21 | Lovercheck Dale R. | Unit dose of material in system and method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6372525B1 (en) * | 1999-12-20 | 2002-04-16 | Taiwan Semiconductor Manufacturing Company | Wafer-level antenna effect detection pattern for VLSI |
| US6372252B1 (en) * | 2000-04-28 | 2002-04-16 | Adams Laboratories, Inc. | Guaifenesin sustained release formulation and tablets |
-
2003
- 2003-04-15 CN CN038125110A patent/CN1655766B/zh not_active Expired - Fee Related
- 2003-04-15 JP JP2003585704A patent/JP5466346B2/ja not_active Expired - Fee Related
- 2003-04-15 CA CA2481739A patent/CA2481739C/en not_active Expired - Lifetime
- 2003-04-15 WO PCT/US2003/011500 patent/WO2003088952A1/en not_active Ceased
- 2003-04-15 EA EA200401369A patent/EA007156B1/ru not_active IP Right Cessation
- 2003-04-15 AU AU2003237807A patent/AU2003237807B2/en not_active Ceased
- 2003-04-15 EP EP03736462A patent/EP1503739A4/de not_active Ceased
- 2003-04-15 MX MXPA04010225A patent/MXPA04010225A/es active IP Right Grant
- 2003-04-15 IL IL16443803A patent/IL164438A0/xx unknown
-
2004
- 2004-11-11 ZA ZA2004/09171A patent/ZA200409171B/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| US4552899B1 (de) * | 1984-04-09 | 1992-10-20 | Analgesic Associates | |
| EP0384514A2 (de) * | 1989-02-21 | 1990-08-29 | Norwich Eaton Pharmaceuticals, Inc. | Tablette mit Doppelwirkung |
| WO2000033818A1 (en) * | 1998-12-11 | 2000-06-15 | Nostrum Pharmaceuticals, Inc. | Sustained release tablet containing hydrocolloid and cellulose ether |
| WO2001019901A2 (en) * | 1999-09-14 | 2001-03-22 | Smithkline Beecham Corporation | Process for making aqueous coated beadlets |
| US20020022058A1 (en) * | 2000-07-08 | 2002-02-21 | Lovercheck Dale R. | Unit dose of material in system and method |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO03088952A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003237807B2 (en) | 2008-10-23 |
| CA2481739A1 (en) | 2003-10-30 |
| EA200401369A1 (ru) | 2005-06-30 |
| EA007156B1 (ru) | 2006-08-25 |
| EP1503739A1 (de) | 2005-02-09 |
| WO2003088952A1 (en) | 2003-10-30 |
| MXPA04010225A (es) | 2005-07-05 |
| CA2481739C (en) | 2012-10-02 |
| JP2005528402A (ja) | 2005-09-22 |
| IL164438A0 (en) | 2005-12-18 |
| CN1655766B (zh) | 2012-05-30 |
| JP5466346B2 (ja) | 2014-04-09 |
| AU2003237807A1 (en) | 2003-11-03 |
| ZA200409171B (en) | 2005-07-27 |
| CN1655766A (zh) | 2005-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20041029 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1072906 Country of ref document: HK |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ADAMS RESPIRATORY THERAPEUTICS, INC. |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20060523 |
|
| 17Q | First examination report despatched |
Effective date: 20071031 |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: RECKITT, BENCKISER, INC. |
|
| APBK | Appeal reference recorded |
Free format text: ORIGINAL CODE: EPIDOSNREFNE |
|
| APBN | Date of receipt of notice of appeal recorded |
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| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: RECKITT BENCKISER LLC |
|
| APBR | Date of receipt of statement of grounds of appeal recorded |
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| APAF | Appeal reference modified |
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| APBT | Appeal procedure closed |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 18R | Application refused |
Effective date: 20150126 |