EP1556022A4 - Compositions pharmaceutiques aqueuses 2,6-diisopropylphenol - Google Patents

Compositions pharmaceutiques aqueuses 2,6-diisopropylphenol

Info

Publication number
EP1556022A4
EP1556022A4 EP03759636A EP03759636A EP1556022A4 EP 1556022 A4 EP1556022 A4 EP 1556022A4 EP 03759636 A EP03759636 A EP 03759636A EP 03759636 A EP03759636 A EP 03759636A EP 1556022 A4 EP1556022 A4 EP 1556022A4
Authority
EP
European Patent Office
Prior art keywords
diisopropylphenol
pharmaceutical compositions
aqueous pharmaceutical
aqueous
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03759636A
Other languages
German (de)
English (en)
Other versions
EP1556022A1 (fr
Inventor
Zhong Zhang
Orn Almarsson
Hongming Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transform Pharmaceuticals Inc
Original Assignee
Transform Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/629,308 external-priority patent/US7915317B2/en
Application filed by Transform Pharmaceuticals Inc filed Critical Transform Pharmaceuticals Inc
Publication of EP1556022A1 publication Critical patent/EP1556022A1/fr
Publication of EP1556022A4 publication Critical patent/EP1556022A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP03759636A 2002-10-29 2003-10-02 Compositions pharmaceutiques aqueuses 2,6-diisopropylphenol Withdrawn EP1556022A4 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US629308 1996-04-08
US42219502P 2002-10-29 2002-10-29
US422195P 2002-10-29
US43697902P 2002-12-30 2002-12-30
US436979P 2002-12-30
US44349003P 2003-01-29 2003-01-29
US443490P 2003-01-29
US46245003P 2003-04-11 2003-04-11
US462450P 2003-04-11
US46431403P 2003-04-21 2003-04-21
US464314P 2003-04-21
US47040303P 2003-05-14 2003-05-14
US470403P 2003-05-14
US48535403P 2003-07-07 2003-07-07
US485354P 2003-07-07
US10/629,308 US7915317B2 (en) 2002-07-29 2003-07-29 Aqueous 2,6-diisopropylphenol pharmaceutical compositions
PCT/US2003/031086 WO2004039360A1 (fr) 2002-10-29 2003-10-02 Compositions pharmaceutiques aqueuses 2,6-diisopropylphenol

Publications (2)

Publication Number Publication Date
EP1556022A1 EP1556022A1 (fr) 2005-07-27
EP1556022A4 true EP1556022A4 (fr) 2010-03-10

Family

ID=32234547

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03759636A Withdrawn EP1556022A4 (fr) 2002-10-29 2003-10-02 Compositions pharmaceutiques aqueuses 2,6-diisopropylphenol

Country Status (3)

Country Link
EP (1) EP1556022A4 (fr)
AU (1) AU2003275360A1 (fr)
WO (1) WO2004039360A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
JP2022526976A (ja) * 2019-04-05 2022-05-27 ソレント・セラピューティクス・インコーポレイテッド カンナビジオール医薬組成物
CN114601800B (zh) * 2021-09-28 2023-07-28 天津瑞普生物技术股份有限公司 一种甲磷丙泊酚钠无菌粉针剂及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056635A (en) * 1974-03-28 1977-11-01 Imperial Chemical Industries Limited 2,6-Diisopropylphenol as an anaesthetic agent
WO2000078301A1 (fr) * 1999-06-21 2000-12-28 Kuhnil Pharm. Co., Ltd. Composition d'anesthesiant en injection intraveineuse comprenant du propofol
WO2002009671A2 (fr) * 2000-08-01 2002-02-07 University Of Florida Nouveaux systemes de micro-emulsions et de tensioactifs destines a la solubilisation de medicaments
WO2003030862A2 (fr) * 2001-10-08 2003-04-17 Maelor Pharmaceuticals Limited Compositions anesthesiques et methode d'administration de ces dernieres

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69912441T2 (de) * 1998-08-19 2004-08-19 Skyepharma Canada Inc., Verdun Injizierbare wässerige propofoldispersionen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056635A (en) * 1974-03-28 1977-11-01 Imperial Chemical Industries Limited 2,6-Diisopropylphenol as an anaesthetic agent
WO2000078301A1 (fr) * 1999-06-21 2000-12-28 Kuhnil Pharm. Co., Ltd. Composition d'anesthesiant en injection intraveineuse comprenant du propofol
WO2002009671A2 (fr) * 2000-08-01 2002-02-07 University Of Florida Nouveaux systemes de micro-emulsions et de tensioactifs destines a la solubilisation de medicaments
WO2003030862A2 (fr) * 2001-10-08 2003-04-17 Maelor Pharmaceuticals Limited Compositions anesthesiques et methode d'administration de ces dernieres

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2004039360A1 *

Also Published As

Publication number Publication date
WO2004039360A1 (fr) 2004-05-13
AU2003275360A1 (en) 2004-05-25
WO2004039360B1 (fr) 2004-06-17
EP1556022A1 (fr) 2005-07-27
AU2003275360A8 (en) 2004-05-25

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