EP1556065A4 - Verfahren zur isolierung von unterpopulationen von proteinen, die in protein-protein-wechselwirkungen eingreifen - Google Patents

Verfahren zur isolierung von unterpopulationen von proteinen, die in protein-protein-wechselwirkungen eingreifen

Info

Publication number
EP1556065A4
EP1556065A4 EP02761370A EP02761370A EP1556065A4 EP 1556065 A4 EP1556065 A4 EP 1556065A4 EP 02761370 A EP02761370 A EP 02761370A EP 02761370 A EP02761370 A EP 02761370A EP 1556065 A4 EP1556065 A4 EP 1556065A4
Authority
EP
European Patent Office
Prior art keywords
protein
undoppululations
isolating
proteins
interact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02761370A
Other languages
English (en)
French (fr)
Other versions
EP1556065A1 (de
Inventor
Daniel L Alkon
Thomas J Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Blanchette Rockefeller Neurosciences Institute
Original Assignee
Blanchette Rockefeller Neurosciences Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blanchette Rockefeller Neurosciences Institute filed Critical Blanchette Rockefeller Neurosciences Institute
Publication of EP1556065A1 publication Critical patent/EP1556065A1/de
Publication of EP1556065A4 publication Critical patent/EP1556065A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP02761370A 2002-08-14 2002-08-14 Verfahren zur isolierung von unterpopulationen von proteinen, die in protein-protein-wechselwirkungen eingreifen Withdrawn EP1556065A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/025845 WO2004019967A1 (en) 2002-08-14 2002-08-14 Method for isolating subpopulations of proteins that engage in protein-protein interactions

Publications (2)

Publication Number Publication Date
EP1556065A1 EP1556065A1 (de) 2005-07-27
EP1556065A4 true EP1556065A4 (de) 2005-10-19

Family

ID=31975561

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02761370A Withdrawn EP1556065A4 (de) 2002-08-14 2002-08-14 Verfahren zur isolierung von unterpopulationen von proteinen, die in protein-protein-wechselwirkungen eingreifen

Country Status (6)

Country Link
EP (1) EP1556065A4 (de)
JP (1) JP2005535727A (de)
CN (1) CN1658892A (de)
AU (1) AU2002326644A1 (de)
CA (1) CA2492324A1 (de)
WO (1) WO2004019967A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3465207T1 (sl) 2016-05-30 2022-01-31 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E. V. Identifikacija ligandov s KO-frakcionacijo
CN109932444B (zh) * 2019-03-19 2022-03-11 北京泰德制药股份有限公司 一种糖蛋白多种电荷异构体翻译后修饰的评价方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817789A (en) * 1995-06-06 1998-10-06 Transkaryotic Therapies, Inc. Chimeric proteins for use in transport of a selected substance into cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MOLECULAR & CELLULAR PROTEOMICS., vol. 1, no. 3, March 2002 (2002-03-01), US ASBBM, BIRMINGHAM, AL., pages 253 - 259, XP002958852 *

Also Published As

Publication number Publication date
JP2005535727A (ja) 2005-11-24
WO2004019967A1 (en) 2004-03-11
CN1658892A (zh) 2005-08-24
CA2492324A1 (en) 2004-03-11
AU2002326644A1 (en) 2004-03-19
EP1556065A1 (de) 2005-07-27

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