EP1572079A4 - Corps mimetiques de cdr de mammifere, compositions, procedes et utilisations - Google Patents
Corps mimetiques de cdr de mammifere, compositions, procedes et utilisationsInfo
- Publication number
- EP1572079A4 EP1572079A4 EP03718053A EP03718053A EP1572079A4 EP 1572079 A4 EP1572079 A4 EP 1572079A4 EP 03718053 A EP03718053 A EP 03718053A EP 03718053 A EP03718053 A EP 03718053A EP 1572079 A4 EP1572079 A4 EP 1572079A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- mimetibodies
- compositions
- methods
- cdr
- mammalian
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36879102P | 2002-03-29 | 2002-03-29 | |
| US368791P | 2002-03-29 | ||
| PCT/US2003/009139 WO2003084477A2 (fr) | 2002-03-29 | 2003-03-24 | Corps mimetiques de cdr de mammifere, compositions, procedes et utilisations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP1572079A3 EP1572079A3 (fr) | 2005-09-09 |
| EP1572079A2 EP1572079A2 (fr) | 2005-09-14 |
| EP1572079A4 true EP1572079A4 (fr) | 2006-09-06 |
Family
ID=28791903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03718053A Withdrawn EP1572079A4 (fr) | 2002-03-29 | 2003-03-24 | Corps mimetiques de cdr de mammifere, compositions, procedes et utilisations |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1572079A4 (fr) |
| AU (1) | AU2003222069A1 (fr) |
| WO (1) | WO2003084477A2 (fr) |
Families Citing this family (102)
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| CA2490409A1 (fr) * | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Corps mimetiques mammaliens a deletion ch1, compositions, procedes et utilisations |
| US7927599B2 (en) | 2003-09-08 | 2011-04-19 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
| US8257963B2 (en) | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
| US7897384B2 (en) * | 2003-09-08 | 2011-03-01 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
| UA89481C2 (uk) * | 2003-09-30 | 2010-02-10 | Центокор, Инк. | Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування |
| DE10353175A1 (de) | 2003-11-14 | 2005-06-16 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
| EP1531162A1 (fr) | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Anticorps SAM-6, spécifique d'adénocarcinome, et ses utilisations |
| WO2005063282A1 (fr) * | 2003-12-23 | 2005-07-14 | Centocor, Inc. | Agents antiretroviraux, compositions et methodes d'utilisation |
| ITMI20041569A1 (it) * | 2004-07-30 | 2004-10-30 | Tecnogen Scpa | "ligandi peptidici specifici per le immunoglobuline" |
| EP1799700A4 (fr) | 2004-09-27 | 2009-02-11 | Centocor Inc | Corps mimetiques srage, compositions, et methodes d'utilisation |
| AU2008304111B2 (en) | 2007-09-27 | 2014-04-24 | Amgen Inc. | Pharmaceutical formulations |
| EP3381445B1 (fr) | 2007-11-15 | 2023-10-25 | Amgen Inc. | Formulation aqueuse d'anticorps stabilisée par des antioxydants pour administration parentérale |
| AU2009206306B2 (en) | 2008-01-25 | 2013-06-06 | Amgen Inc. | Ferroportin antibodies and methods of use |
| JP2011519279A (ja) | 2008-05-01 | 2011-07-07 | アムジエン・インコーポレーテツド | 抗ヘプシジン抗体及び使用の方法 |
| EP2349332B1 (fr) | 2008-11-13 | 2019-10-23 | The General Hospital Corporation | Procédés et compositions pour la régulation de l'homéostasie du fer par modulation de la protéine bmp-6 |
| IT1395137B1 (it) * | 2009-08-05 | 2012-09-05 | Spider Biotech S R L | Nuovi peptidi antipatogeni |
| MX344382B (es) | 2009-10-23 | 2016-12-14 | Amgen Inc * | Adaptador de vial y sistema. |
| ES2545411T5 (es) | 2010-06-07 | 2024-04-05 | Amgen Inc | Dispositivo de administración de fármaco |
| CA2831100C (fr) | 2011-03-31 | 2020-02-18 | Mark Dominis Holt | Adaptateur de flacon et systeme |
| CA3021845C (fr) | 2011-04-20 | 2022-03-29 | Amgen Inc. | Appareil auto-injecteur |
| LT3045187T (lt) | 2011-10-14 | 2019-07-10 | Amgen Inc. | Injekcijų įrenginys ir surinkimo būdas |
| WO2014072411A1 (fr) | 2012-11-08 | 2014-05-15 | Phi Pharma Sa | Molécules de transporteur spécifiques de protéoglycane c4s |
| SI3081249T1 (sl) | 2012-11-21 | 2021-03-31 | Amgen Inc. | Naprava za dajanje zdravila |
| EP2968503B1 (fr) | 2013-03-15 | 2018-08-15 | Intrinsic LifeSciences LLC | Anticorps antihepcidine et leurs utilisations |
| CN105142695B (zh) | 2013-03-15 | 2020-06-02 | 安进公司 | 身体轮廓可调适的自动注射器装置 |
| EP2968775B1 (fr) | 2013-03-15 | 2019-12-18 | Amgen Inc. | Boîte à médicament, autoinjecteur et système d'autoinjecteur |
| TWI580451B (zh) | 2013-03-15 | 2017-05-01 | 安美基公司 | 用於注射器之匣盒及使用具有自動注射器及匣盒之自動注射器設備之方法 |
| SG11201507878SA (en) | 2013-03-22 | 2015-10-29 | Amgen Inc | Injector and method of assembly |
| EP3060281B1 (fr) | 2013-10-24 | 2019-01-30 | Amgen Inc. | Système de distribution de médicaments équipé d'un dispositif de commande sensible à la température |
| EP3421066B1 (fr) | 2013-10-24 | 2021-03-03 | Amgen Inc. | Injecteur et procédé d'assemblage |
| WO2015119906A1 (fr) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Système d'administration de médicament doté d'un générateur de champ électromagnétique |
| JP6640113B2 (ja) | 2014-05-07 | 2020-02-05 | アムジエン・インコーポレーテツド | 衝撃低減要素を有する自動注入器 |
| CN112237662B (zh) | 2014-06-03 | 2022-10-21 | 安姆根有限公司 | 药物递送系统和使用方法 |
| WO2016049036A1 (fr) | 2014-09-22 | 2016-03-31 | Intrinsic Lifesciences Llc | Anticorps anti-hepcidine humanisés et utilisations de ceux-ci |
| WO2016061220A2 (fr) | 2014-10-14 | 2016-04-21 | Amgen Inc. | Dispositif d'injection de médicament comportant des témoins visuels et sonores |
| EP3848072A1 (fr) | 2014-12-19 | 2021-07-14 | Amgen Inc. | Dispositif d'administration de médicament comportant un capteur de proximité |
| US11357916B2 (en) | 2014-12-19 | 2022-06-14 | Amgen Inc. | Drug delivery device with live button or user interface field |
| CA2976935C (fr) | 2015-02-17 | 2020-03-10 | Amgen Inc. | Dispositif d'administration de medicament a securisation assistee par depression et/ou retour d'informations |
| WO2016138434A1 (fr) | 2015-02-27 | 2016-09-01 | Amgen Inc. | Dispositif d'administration de médicament ayant un mécanisme de protection d'aiguille présentant un seuil réglable de résistance au mouvement de l'élément de protection d'aiguille |
| WO2017039786A1 (fr) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Adaptateur d'ensemble de seringue pour une seringue |
| ES2755717T3 (es) | 2015-12-09 | 2020-04-23 | Amgen Inc | Autoinyector con tapa de señalización |
| US11154661B2 (en) | 2016-01-06 | 2021-10-26 | Amgen Inc. | Auto-injector with signaling electronics |
| IL302725A (en) * | 2016-01-13 | 2023-07-01 | Regeneron Pharma | Rodents having an engineered heavy chain diversity region |
| US11200298B2 (en) | 2016-03-15 | 2021-12-14 | Amgen Inc. | Reducing probability of glass breakage in drug delivery devices |
| US11541168B2 (en) | 2016-04-29 | 2023-01-03 | Amgen Inc. | Drug delivery device with messaging label |
| WO2017192287A1 (fr) | 2016-05-02 | 2017-11-09 | Amgen Inc. | Adaptateur de seringue et guide pour remplir un injecteur sur le corps |
| EP3455142B1 (fr) | 2016-05-13 | 2023-08-09 | Amgen Inc. | Ensemble manchon de flacon |
| US11238150B2 (en) | 2016-05-16 | 2022-02-01 | Amgen Inc. | Data encryption in medical devices with limited computational capability |
| US11541176B2 (en) | 2016-06-03 | 2023-01-03 | Amgen Inc. | Impact testing apparatuses and methods for drug delivery devices |
| WO2018004842A1 (fr) | 2016-07-01 | 2018-01-04 | Amgen Inc. | Dispositif d'administration de médicament présentant un risque réduit au minimum de fracture de composant lors d'événements d'impact |
| WO2018034784A1 (fr) | 2016-08-17 | 2018-02-22 | Amgen Inc. | Dispositif d'administration de médicament avec détection de positionnement. |
| US20200261643A1 (en) | 2016-10-25 | 2020-08-20 | Amgen Inc. | On-body injector |
| WO2018136398A1 (fr) | 2017-01-17 | 2018-07-26 | Amgen Inc. | Dispositifs d'injection et procédés d'utilisation et d'assemblage associés |
| US11369736B2 (en) | 2017-02-17 | 2022-06-28 | Amgen Inc. | Cannula insertion and retraction mechanisms |
| US11752258B2 (en) | 2017-02-17 | 2023-09-12 | Amgen Inc. | Drug delivery device with sterile fluid flowpath and related method of assembly |
| CA3050927A1 (fr) | 2017-03-06 | 2018-09-13 | Brian Stonecipher | Dispositif d'administration de medicaments dote d'une fonction de prevention d'activation |
| KR102627069B1 (ko) | 2017-03-07 | 2024-01-18 | 암겐 인코포레이티드 | 과압에 의한 바늘 삽입 |
| EP3592404A1 (fr) | 2017-03-09 | 2020-01-15 | Amgen Inc. | Mécanisme d'insertion pour dispositif d'administration de médicament |
| EP3570871B1 (fr) | 2017-03-20 | 2020-11-18 | H. Hoffnabb-La Roche Ag | Procédé de glyco-ingénierie in vitro d'une protéine de stimulation de l'érythropoïèse |
| KR102651078B1 (ko) | 2017-03-28 | 2024-03-22 | 암겐 인코포레이티드 | 플런저 로드 및 주사기 조립 시스템 및 방법 |
| JP7200134B2 (ja) | 2017-06-08 | 2023-01-06 | アムジエン・インコーポレーテツド | トルク駆動式薬物送達デバイス |
| US11590294B2 (en) | 2017-06-08 | 2023-02-28 | Amgen Inc. | Syringe assembly for a drug delivery device and method of assembly |
| JP7195276B2 (ja) | 2017-06-22 | 2022-12-23 | アムジエン・インコーポレーテツド | デバイス起動による衝突／衝撃の低減 |
| MA49461A (fr) | 2017-06-23 | 2020-04-29 | Amgen Inc | Dispositif électronique d'administration de médicament comprenant un bouchon activé par un ensemble commutateur |
| MA49562A (fr) | 2017-07-14 | 2020-05-20 | Amgen Inc | Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion |
| EP3655063A1 (fr) | 2017-07-21 | 2020-05-27 | Amgen Inc. | Élément d'étanchéité perméable aux gaz pour récipient à médicament et procédés d'assemblage |
| US11484648B2 (en) | 2017-07-25 | 2022-11-01 | Amgen Inc. | Drug delivery device with container access system and related method of assembly |
| MA49677A (fr) | 2017-07-25 | 2021-04-21 | Amgen Inc | Dispositif d'administration de médicament avec module d'engrenage et procédé d'assemblage associé |
| MA49838A (fr) | 2017-08-09 | 2020-06-17 | Amgen Inc | Systèm de administration de médicaments avec pression hydraulique-pneumatique de chambre |
| WO2019036181A1 (fr) | 2017-08-18 | 2019-02-21 | Amgen Inc. | Injecteur sur-corps avec patch adhésif stérile |
| US11103636B2 (en) | 2017-08-22 | 2021-08-31 | Amgen Inc. | Needle insertion mechanism for drug delivery device |
| WO2019070472A1 (fr) | 2017-10-04 | 2019-04-11 | Amgen Inc. | Adaptateur d'écoulement destiné à un dispositif d'administration de médicament |
| CN111132711B (zh) | 2017-10-06 | 2022-07-01 | 安进公司 | 带有联锁组件的药物递送装置及相关组装方法 |
| MA50348A (fr) | 2017-10-09 | 2020-08-19 | Amgen Inc | Dispositif d'administration de médicament comprenant un ensemble d'entraînement et procédé d'assemblage associé |
| WO2019090086A1 (fr) | 2017-11-03 | 2019-05-09 | Amgen Inc. | Systèmes et approches pour stériliser un dispositif d'administration de médicament |
| US20200261648A1 (en) | 2017-11-06 | 2020-08-20 | Amgen Inc. | Drug delivery device with placement and flow sensing |
| IL273664B1 (en) | 2017-11-06 | 2026-02-01 | Amgen Inc | Full-fledged assemblies and related methods |
| IL319987A (en) | 2017-11-10 | 2025-06-01 | Amgen Inc | Plungers for drug delivery devices |
| SG11202003004RA (en) | 2017-11-16 | 2020-04-29 | Amgen Inc | Door latch mechanism for drug delivery device |
| AU2018368338B2 (en) | 2017-11-16 | 2024-07-25 | Amgen Inc. | Autoinjector with stall and end point detection |
| CN108129561B (zh) * | 2017-12-06 | 2021-05-25 | 渤海大学 | 一种ace抑制肽 |
| US10835685B2 (en) | 2018-05-30 | 2020-11-17 | Amgen Inc. | Thermal spring release mechanism for a drug delivery device |
| US11083840B2 (en) | 2018-06-01 | 2021-08-10 | Amgen Inc. | Modular fluid path assemblies for drug delivery devices |
| WO2020023336A1 (fr) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Dispositifs hybrides d'administration de médicament dotés d'une partie de préhension |
| WO2020023451A1 (fr) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Dispositifs d'administration pour l'administration de médicaments |
| WO2020023220A1 (fr) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Dispositifs d'administration de médicament hybrides dotés d'une partie de fixation collante à placer sur la peau et procédé de préparation associé |
| CA3103681A1 (fr) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Dispositifs d'administration pour l'administration de medicaments |
| EP3829692A1 (fr) | 2018-07-31 | 2021-06-09 | Amgen Inc. | Ensemble de trajet de fluide pour dispositif d'administration de médicament |
| EP3856284A1 (fr) | 2018-09-24 | 2021-08-04 | Amgen Inc. | Systèmes et procédés de dosage interventionnel |
| MA53718A (fr) | 2018-09-28 | 2022-01-05 | Amgen Inc | Ensemble d'activation d'échappement de fil de muscle pour un dispositif d'administration de médicament |
| MX2021003492A (es) | 2018-10-02 | 2021-06-18 | Amgen Inc | Sistemas de inyeccion para la administracion de farmacos con transmision de fuerza interna. |
| JP7547325B2 (ja) | 2018-10-05 | 2024-09-09 | アムジエン・インコーポレーテツド | 投薬量インジケータを有する薬物送達デバイス |
| SG11202103800RA (en) | 2018-10-15 | 2021-05-28 | Amgen Inc | Drug delivery device having damping mechanism |
| AU2019359801B2 (en) | 2018-10-15 | 2025-01-02 | Amgen Inc. | Platform assembly process for drug delivery device |
| MA54057A (fr) | 2018-11-01 | 2022-02-09 | Amgen Inc | Dispositifs d'administration de médicament à rétraction partielle d'élément d'administration de médicament |
| TWI831847B (zh) | 2018-11-01 | 2024-02-11 | 美商安進公司 | 部分針頭縮回之藥物遞送裝置及其操作方法 |
| ES3010833T3 (en) | 2018-11-01 | 2025-04-04 | Amgen Inc | Drug delivery devices with partial drug delivery member retraction |
| AU2020263289B2 (en) | 2019-04-24 | 2025-05-22 | Amgen Inc. | Syringe sterilization verification assemblies and methods |
| MX2022002149A (es) | 2019-08-23 | 2022-03-17 | Amgen Inc | Dispositivo de suministro de farmacos con componentes de acoplamiento de capuchon de aguja configurable y metodos relacionados. |
| MX2023013640A (es) | 2021-05-21 | 2023-11-30 | Amgen Inc | Metodo de optimizacion de una receta de llenado para un contenedor de medicamento. |
| KR20250099137A (ko) | 2022-11-02 | 2025-07-01 | 에프. 호프만-라 로슈 아게 | 당단백질 조성물의 생산 방법 |
| WO2026030152A1 (fr) | 2024-07-29 | 2026-02-05 | Amgen Inc. | Système et procédé d'évaluation de la transférabilité d'une recette de remplissage |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004002417A2 (fr) * | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Corps mimetiques mammaliens a deletion ch1, compositions, procedes et utilisations |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6235294A (en) * | 1993-02-02 | 1994-08-29 | Scripps Research Institute, The | Methods for producing polypeptide binding sites |
-
2003
- 2003-03-24 EP EP03718053A patent/EP1572079A4/fr not_active Withdrawn
- 2003-03-24 AU AU2003222069A patent/AU2003222069A1/en not_active Abandoned
- 2003-03-24 WO PCT/US2003/009139 patent/WO2003084477A2/fr not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004002417A2 (fr) * | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Corps mimetiques mammaliens a deletion ch1, compositions, procedes et utilisations |
Non-Patent Citations (1)
| Title |
|---|
| BEREZOV A ET AL: "Disabling erbB receptors with rationally designed exocyclic mimetics of antibodies: structure-function analysis.", JOURNAL OF MEDICINAL CHEMISTRY. 2 AUG 2001, vol. 44, no. 16, 2 August 2001 (2001-08-02), pages 2565 - 2574, XP002390205, ISSN: 0022-2623 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003222069A1 (en) | 2003-10-20 |
| WO2003084477A2 (fr) | 2003-10-16 |
| AU2003222069A8 (en) | 2003-10-20 |
| WO2003084477A3 (fr) | 2005-09-09 |
| EP1572079A2 (fr) | 2005-09-14 |
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