EP1659996A4 - Citrus sesquiterpen-synthase, herstellungs- und anwendungsverfahren dafür - Google Patents

Citrus sesquiterpen-synthase, herstellungs- und anwendungsverfahren dafür

Info

Publication number
EP1659996A4
EP1659996A4 EP04770466A EP04770466A EP1659996A4 EP 1659996 A4 EP1659996 A4 EP 1659996A4 EP 04770466 A EP04770466 A EP 04770466A EP 04770466 A EP04770466 A EP 04770466A EP 1659996 A4 EP1659996 A4 EP 1659996A4
Authority
EP
European Patent Office
Prior art keywords
citrus
production
methods
sesquiterpene synthase
sesquiterpene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04770466A
Other languages
English (en)
French (fr)
Other versions
EP1659996A2 (de
Inventor
Yoram Eyal
Efraim Lewinsohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
State of Israel
Original Assignee
State of Israel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by State of Israel filed Critical State of Israel
Publication of EP1659996A2 publication Critical patent/EP1659996A2/de
Publication of EP1659996A4 publication Critical patent/EP1659996A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cosmetics (AREA)
EP04770466A 2003-09-02 2004-09-02 Citrus sesquiterpen-synthase, herstellungs- und anwendungsverfahren dafür Withdrawn EP1659996A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49902403P 2003-09-02 2003-09-02
PCT/IL2004/000795 WO2005021705A2 (en) 2003-09-02 2004-09-02 Citrus sesquiterpene synthase, methods of production and uses thereof

Publications (2)

Publication Number Publication Date
EP1659996A2 EP1659996A2 (de) 2006-05-31
EP1659996A4 true EP1659996A4 (de) 2008-07-02

Family

ID=34272763

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04770466A Withdrawn EP1659996A4 (de) 2003-09-02 2004-09-02 Citrus sesquiterpen-synthase, herstellungs- und anwendungsverfahren dafür

Country Status (5)

Country Link
EP (1) EP1659996A4 (de)
JP (1) JP2007517496A (de)
AU (1) AU2004269197A1 (de)
CA (1) CA2537505A1 (de)
WO (1) WO2005021705A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0314979B1 (pt) 2002-10-04 2019-10-22 Firmenich S.A método de produção de um valenceno e microorganismo transgênico
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
WO2009109597A1 (en) 2008-03-06 2009-09-11 Firmenich Sa Method for producing alpha- santalene
JP5649020B2 (ja) * 2008-10-10 2015-01-07 国立大学法人岩手大学 組換えａｌｓｖによるダイズ内在性遺伝子の発現抑制
JP2013544084A (ja) 2010-10-29 2013-12-12 アリリクス・インコーポレイテッド 改変されたバレンセンシンターゼポリペプチド、コーディング核酸分子およびその使用
EP2537926A1 (de) * 2011-06-21 2012-12-26 Isobionics B.V. Valencensynthase
US20150250166A1 (en) 2012-08-23 2015-09-10 Allylix, Inc. Nootkatone as an insecticide and insect repellent
WO2014150599A1 (en) 2013-03-14 2014-09-25 Allylix, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2540791B1 (es) * 2013-12-13 2016-05-09 Consejo Superior De Investigaciones Científicas (Csic) Nuevas sesquiterpeno sintasas aisladas de la piel de naranja.
WO2019161141A1 (en) 2018-02-14 2019-08-22 Ginkgo Bioworks Chimeric terpene synthases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031376A2 (en) * 2002-10-04 2004-04-15 Firmenich Sa Sesquiterpene synthases and methods of use
US20060218661A1 (en) * 2003-07-24 2006-09-28 Joe Chappell Novel sesquiterpene synthase gene and protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970085A (en) 1989-10-19 1990-11-13 The Procter & Gamble Company Process for making improved citrus aqueous essence and product produced therefrom

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031376A2 (en) * 2002-10-04 2004-04-15 Firmenich Sa Sesquiterpene synthases and methods of use
US20060218661A1 (en) * 2003-07-24 2006-09-28 Joe Chappell Novel sesquiterpene synthase gene and protein

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOHLMANN JORG ET AL: "Plant terpenoid synthases: Molecular biology and phylogenetic analysis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 95, no. 8, 14 April 1998 (1998-04-14), pages 4126 - 4133, XP002171016, ISSN: 0027-8424 *
CHAPPELL JOE: "Valencene synthase - a biochemical magician and harbinger of transgenic aromas", TRENDS IN PLANT SCIENCE, vol. 9, no. 6, June 2004 (2004-06-01), pages 266 - 269, XP002480419, ISSN: 1360-1385 *
DATABASE EMBL [online] 3 April 2002 (2002-04-03), "Citrus x paradisi putative terpene synthase mRNA, complete cds.", XP002480420, retrieved from EBI accession no. EMBL:AF411120 Database accession no. AF411120 *
GREENHAGEN B T: "Origins Of Isoprenoid Diversity: A Study Of Structure-Function Relationsships In Sesquiterpene Synthases - Dissertation", 15 July 2003 (2003-07-15), XP002480418, Retrieved from the Internet <URL:http://lib.uky.edu/ETD/ukyplph2003d00093/Greenhagen.pdf> *
LUCKER J ET AL: "Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 65, no. 19, 1 October 2004 (2004-10-01), pages 2649 - 2659, XP004586632, ISSN: 0031-9422 *
See also references of WO2005021705A2 *
SHARON-ASA L ET AL: "Citrus fruit flavor and aroma biosynthesis: Isolation, functional characterization, and developmental regulation of Cstps1, a key gene in the production of the sesquiterpene aroma compound valencene", PLANT JOURNAL, BLACKWELL SCIENTIFIC PUBLICATIONS, OXFORD, GB, vol. 36, no. 5, 1 December 2003 (2003-12-01), pages 664 - 674, XP002282506, ISSN: 0960-7412 *

Also Published As

Publication number Publication date
WO2005021705A9 (en) 2009-04-16
WO2005021705A8 (en) 2005-12-22
WO2005021705A3 (en) 2005-04-21
WO2005021705A2 (en) 2005-03-10
EP1659996A2 (de) 2006-05-31
JP2007517496A (ja) 2007-07-05
CA2537505A1 (en) 2005-03-10
AU2004269197A1 (en) 2005-03-10

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RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 5/10 20060101ALI20080520BHEP

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Ipc: C12N 15/82 20060101AFI20080520BHEP

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