EP1693182A3 - Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten - Google Patents

Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten Download PDF

Info

Publication number
EP1693182A3
EP1693182A3 EP20060002217 EP06002217A EP1693182A3 EP 1693182 A3 EP1693182 A3 EP 1693182A3 EP 20060002217 EP20060002217 EP 20060002217 EP 06002217 A EP06002217 A EP 06002217A EP 1693182 A3 EP1693182 A3 EP 1693182A3
Authority
EP
European Patent Office
Prior art keywords
layer
pair
filling
tablets
pressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20060002217
Other languages
English (en)
French (fr)
Other versions
EP1693182B1 (de
EP1693182A2 (de
Inventor
Ingo Schmidt
Ulrich Gathmann
Bernd Malner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fette GmbH
Original Assignee
Fette GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fette GmbH filed Critical Fette GmbH
Publication of EP1693182A2 publication Critical patent/EP1693182A2/de
Publication of EP1693182A3 publication Critical patent/EP1693182A3/de
Application granted granted Critical
Publication of EP1693182B1 publication Critical patent/EP1693182B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/005—Control arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B30B11/085—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable for multi-layer articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets

Landscapes

  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Verfahren und Vorrichtung zur Versuchspressung von aus n Schichten bestehenden Tabletten in einer Rundläufer-Tablettenpresse.
Der mit einem Ober- und Unterstempel (Stempelpaar) versehene Rotor (10) wird mit dem Stempelpaar in eine definierte Füllposition gebracht, in der die dem Stempelpaar (30,32) zugeordnete Matrizenbohrung (14) mit dem Material der ersten Schicht der Tablette gefüllt wird, wobei die Füllkurve (38) in eine erste Position, die Auswerferkurve (44) in eine untere Position und Druckrollen in eine erste Pressposition durch zugeordnete Verstellantriebe gebracht werden; anschließend wird der Rotor (10) um eine volle Umdrehung gedreht und das Stempelpaar (30,32) in der Füllposition gestoppt; die Füllkurve (38) wird in eine zweite Füllposition, die Auswerferkurve (44) in die Auswerfposition und die Druckrollen in eine zweite Pressposition verstellt; danach wird die erste Schicht enthaltende Matrizenbohrung (14) mit dem Material der zweiten Schicht befüllt usw.; bei der n-ten Umdrehung wird vom Unterstempel (32) die n Schichttablette ausgeworfen.
EP20060002217 2005-02-19 2006-02-03 Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten Expired - Lifetime EP1693182B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE200510007790 DE102005007790B4 (de) 2005-02-19 2005-02-19 Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten

Publications (3)

Publication Number Publication Date
EP1693182A2 EP1693182A2 (de) 2006-08-23
EP1693182A3 true EP1693182A3 (de) 2008-07-30
EP1693182B1 EP1693182B1 (de) 2013-12-11

Family

ID=36129760

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20060002217 Expired - Lifetime EP1693182B1 (de) 2005-02-19 2006-02-03 Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten

Country Status (3)

Country Link
US (2) US8119045B2 (de)
EP (1) EP1693182B1 (de)
DE (1) DE102005007790B4 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005007790B4 (de) 2005-02-19 2007-06-28 Fette Gmbh Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
EP2671507A3 (de) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-Informatiksystem
DE102005030312B4 (de) 2005-06-23 2011-05-05 Korsch Ag Rundläufer-Tablettiermaschine und Verfahren zur Herstellung einer Mehrschichttablette
WO2008016183A1 (fr) * 2006-08-04 2008-02-07 Brother Kogyo Kabushiki Kaisha Appareil de formation d'image
BR122013009559A2 (pt) 2009-04-28 2019-08-06 Proteus Digital Health, Inc. Marcadores de evento de ingerível altamente confiável e métodos para usar os mesmos
UA109424C2 (uk) * 2009-12-02 2015-08-25 Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки
WO2011127252A2 (en) 2010-04-07 2011-10-13 Proteus Biomedical, Inc. Miniature ingestible device
US9107806B2 (en) 2010-11-22 2015-08-18 Proteus Digital Health, Inc. Ingestible device with pharmaceutical product
DE102011101286B4 (de) * 2011-05-10 2013-10-17 Fette Compacting Gmbh Rundläuferpresse und Verfahren zum Betreiben einer Rundläuferpresse
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
JP2016508529A (ja) 2013-01-29 2016-03-22 プロテウス デジタル ヘルス， インコーポレイテッド 高度に膨張可能なポリマーフィルムおよびこれを含む組成物
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
EP2977195A1 (de) * 2014-07-21 2016-01-27 M & R Automation GmbH Vorrichtung und Verfahren zur Herstellung von Mehrschichttabletten
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
SG10202101937PA (en) 2016-07-22 2021-03-30 Proteus Digital Health Inc Electromagnetic sensing and detection of ingestible event markers
WO2018081337A1 (en) 2016-10-26 2018-05-03 Proteus Digital Health, Inc. Methods for manufacturing capsules with ingestible event markers
CN110150707A (zh) * 2017-12-28 2019-08-23 浙江东来天然生物制品有限公司 条状食品成型设备
CN108572602B (zh) * 2018-07-23 2024-03-15 上海海得控制系统股份有限公司 一种压片机的控制装置
NL2021552B1 (en) * 2018-09-03 2020-04-30 Besi Netherlands Bv Method and device for selective separating electronic components from a frame with electronic components
DE102023125660B3 (de) * 2023-09-21 2025-02-13 Fette Compacting Gmbh Verfahren zur Versuchspressung von Presslingen in einer Rundläuferpresse
DE102023135488A1 (de) * 2023-12-18 2025-06-18 Fette Compacting Gmbh Vorrichtung und Verfahren zum Entstauben von Tabletten oder Kapseln

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572816A1 (de) * 1992-06-02 1993-12-08 Wilhelm Fette GmbH Verfahren und Vorrichtung zum Pressen von Zweischichttabletten in einer Doppelrundläuferpresse
DE10319024B3 (de) * 2003-04-28 2004-08-12 Fette Gmbh Verfahren zur Versuchspressung von Tabletten

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569198A (de) * 1957-07-12
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
DE2742572B1 (de) * 1977-09-22 1979-03-29 Fette Wilhelm Gmbh Verfahren zum Herstellen von Tabletten und Tablettenpresse
DE3520203A1 (de) * 1985-06-05 1986-12-11 Wilhelm Fette Gmbh, 2053 Schwarzenbek Rundlaeufer-tablettiermaschine und verfahren zur steuerung ihrer druckrollen
US4880373A (en) * 1988-04-28 1989-11-14 The Upjohn Company Tablet press
DE3939956A1 (de) * 1989-12-02 1991-06-06 Fette Wilhelm Gmbh Verfahren und einrichtung zum ueberwachen der presskraefte einer tablettiermaschine
US5223192A (en) * 1989-12-02 1993-06-29 Firma Wilhelm Fette Gmbh Method of and arrangement for monitoring pressing forces in a pelletizing machine
US5322655A (en) * 1993-02-19 1994-06-21 Thomas Engineering, Inc. Method for monitoring and controlling the weights of each layer of a multilayer tablet
DE19844390B4 (de) * 1998-09-28 2005-09-22 Wilhelm Fette Gmbh Verfahren zur Herstellung von Tabletten in einer Rundläufertablettiermaschine
DE19964225C2 (de) * 1999-12-17 2002-01-24 Henkel Kgaa Preßverfahren für mehrphasige Formkörper
DE10161572B4 (de) * 2001-12-14 2004-03-25 Wilhelm Fette Gmbh Tablettenpressvorrichtung
DE10202820C1 (de) * 2002-01-25 2003-03-13 Fette Wilhelm Gmbh Satz von Presstempeln und/oder Matrizen für eine Tablettiermaschine
DE10207764B4 (de) * 2002-02-23 2005-11-17 Wilhelm Fette Gmbh Verfahren zur Kontrolle der Montage von Einzelkomponenten und/oder Baugruppen einer Tablettiermaschine
DE102005007790B4 (de) 2005-02-19 2007-06-28 Fette Gmbh Verfahren und Vorrichtung zur Versuchspressung von Mehrschichttabletten oder Manteltabletten

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572816A1 (de) * 1992-06-02 1993-12-08 Wilhelm Fette GmbH Verfahren und Vorrichtung zum Pressen von Zweischichttabletten in einer Doppelrundläuferpresse
DE10319024B3 (de) * 2003-04-28 2004-08-12 Fette Gmbh Verfahren zur Versuchspressung von Tabletten

Also Published As

Publication number Publication date
US8119045B2 (en) 2012-02-21
EP1693182B1 (de) 2013-12-11
DE102005007790A1 (de) 2006-08-24
US8382465B2 (en) 2013-02-26
EP1693182A2 (de) 2006-08-23
US20120195992A1 (en) 2012-08-02
US20060186568A1 (en) 2006-08-24
DE102005007790B4 (de) 2007-06-28

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