EP1708742A4 - Procedes pour ameliorer la reponse immunitaire dans une partie intradermique et composes utilises dans ces procedes - Google Patents

Procedes pour ameliorer la reponse immunitaire dans une partie intradermique et composes utilises dans ces procedes

Info

Publication number
EP1708742A4
EP1708742A4 EP04821303A EP04821303A EP1708742A4 EP 1708742 A4 EP1708742 A4 EP 1708742A4 EP 04821303 A EP04821303 A EP 04821303A EP 04821303 A EP04821303 A EP 04821303A EP 1708742 A4 EP1708742 A4 EP 1708742A4
Authority
EP
European Patent Office
Prior art keywords
methods
immune response
compounds useful
enhancing immune
intradermal compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04821303A
Other languages
German (de)
English (en)
Other versions
EP1708742A2 (fr
Inventor
Robert Campbell
Kevin G Dolan
Jason Alarcon
Wendy D Woodley
John Mikszta
Sheetal Metha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP1708742A2 publication Critical patent/EP1708742A2/fr
Publication of EP1708742A4 publication Critical patent/EP1708742A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP04821303A 2003-12-05 2004-12-06 Procedes pour ameliorer la reponse immunitaire dans une partie intradermique et composes utilises dans ces procedes Withdrawn EP1708742A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52759903P 2003-12-05 2003-12-05
PCT/US2004/041021 WO2005074460A2 (fr) 2003-12-05 2004-12-06 Procedes pour ameliorer la reponse immunitaire dans une partie intradermique et composes utilises dans ces procedes

Publications (2)

Publication Number Publication Date
EP1708742A2 EP1708742A2 (fr) 2006-10-11
EP1708742A4 true EP1708742A4 (fr) 2008-11-05

Family

ID=34837337

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04821303A Withdrawn EP1708742A4 (fr) 2003-12-05 2004-12-06 Procedes pour ameliorer la reponse immunitaire dans une partie intradermique et composes utilises dans ces procedes

Country Status (8)

Country Link
US (2) US20050281832A1 (fr)
EP (1) EP1708742A4 (fr)
JP (1) JP2007516968A (fr)
CN (1) CN1905896A (fr)
AU (1) AU2004315509A1 (fr)
BR (1) BRPI0417225A (fr)
CA (1) CA2548210A1 (fr)
WO (1) WO2005074460A2 (fr)

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WO2003002069A2 (fr) 2001-06-29 2003-01-09 Becton, Dickinson And Company Distribution intradermique de vaccins et d'agents therapeutiques geniques via une microcannule
US7588774B2 (en) * 2003-05-12 2009-09-15 Becton, Dickinson And Company Molecules enhancing dermal delivery of influenza vaccines
WO2006115509A2 (fr) * 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence
US20060121055A1 (en) * 2004-12-06 2006-06-08 Becton, Dickinson And Company, Inc. Compositions with enhanced immunogenicity
US20090304742A1 (en) * 2005-11-04 2009-12-10 Novartis Vaccines And Diagnostics Srl Influenza vaccines with reduced amount of emulsion adjuvant
EP2940129B1 (fr) * 2007-04-06 2020-05-06 Takeda Vaccines, Inc. Procédés et compositions pour virus vivants atténués
AU2008352966C1 (en) 2007-12-18 2014-09-25 Boston Medical Center Corporation Pre- or post-exposure treatment for filovirus or arenavirus infection
AU2008339984A1 (en) * 2007-12-21 2009-07-02 Glaxosmithkline Biologicals S.A. Vaccine
AU2008363648B9 (en) * 2008-10-31 2013-08-22 Tremrx, Inc. Vaccination with poxvirus vectors via mechanical epidermal disruption
US8691502B2 (en) 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
US20140037694A1 (en) 2011-02-25 2014-02-06 Hisamitsu Pharmaceutical Co., Inc. Adjuvant for transdermal or transmucosal administration and pharmaceutical preparation containing same
US9389229B2 (en) * 2012-07-18 2016-07-12 Theranos, Inc. Methods for detecting and measuring aggregation
US9993549B2 (en) 2013-10-31 2018-06-12 Hisamitsu Pharmaceutical Co., Inc. Adjuvant composition, adjuvant preparation containing same, and kit
CA2931460C (fr) * 2013-11-25 2022-03-22 Medline Industries, Inc. Formulations de solution de blocage de catheter
JP5917626B2 (ja) * 2014-07-28 2016-05-18 トレムアールエックス， インコーポレイテッド 機械的表皮破壊を介したポックスウイルスベクターによるワクチン接種
JP6577795B2 (ja) * 2014-09-03 2019-09-18 日東電工株式会社 ビスホスホネート剤を含む細胞性免疫用ワクチン医薬組成物
CN112379087B (zh) * 2020-10-21 2022-02-11 中国医学科学院医学生物学研究所 一种应用于新型冠状病毒灭活疫苗的裂解液及抗原解离的方法

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2001034801A2 (fr) * 1999-11-12 2001-05-17 Fibrogen, Inc. Vaccins contenant de la gelatine recombinante
WO2002074244A2 (fr) * 2001-03-19 2002-09-26 Iomai Corporation Immunostimulation transcutanee
WO2002087494A2 (fr) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals, Sa Nouveau vaccin

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JPH0688911B2 (ja) * 1985-06-06 1994-11-09 国立予防衛生研究所長 インフルエンザワクチン及びその製造方法
CA2054228A1 (fr) * 1990-10-30 1992-05-01 Masaharu Oki Derives muramyldipeptide et vaccin contre l'influenza en comprenant
US6485729B1 (en) * 1993-09-13 2002-11-26 Protein Sciences Corporation Neuraminidase-supplemented compositions
NZ276234A (en) * 1993-11-05 1998-01-26 Bayer Ag Substituted Under Sec An attenuated replicating non pathogenic flavivirus (bovine viral diarrhoea virus - bvdv) vaccine
US5912000A (en) * 1994-09-23 1999-06-15 Zonagen, Inc. Chitosan induced immunopotentiation
US5702717A (en) * 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
GB9522351D0 (en) * 1995-11-01 1996-01-03 Medeva Holdings Bv Vaccine compositions
US5861174A (en) * 1996-07-12 1999-01-19 University Technology Corporation Temperature sensitive gel for sustained delivery of protein drugs
GB9725084D0 (en) * 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
AT408615B (de) * 1998-09-15 2002-01-25 Immuno Ag Neue influenzavirus-impfstoffzusammensetzung
US6734172B2 (en) * 1998-11-18 2004-05-11 Pacific Northwest Research Institute Surface receptor antigen vaccines
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US20030170818A1 (en) * 2000-06-17 2003-09-11 Haley Dana A. Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides
US7767197B2 (en) * 2000-06-22 2010-08-03 Endo Pharmaceuticals Colorado LLC Delivery vehicle composition and methods for delivering antigens and other drugs
US20030171253A1 (en) * 2001-04-19 2003-09-11 Averil Ma Methods and compositions relating to modulation of A20
US20030129161A1 (en) * 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
US20030191056A1 (en) * 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
US7588774B2 (en) * 2003-05-12 2009-09-15 Becton, Dickinson And Company Molecules enhancing dermal delivery of influenza vaccines
US7978710B2 (en) * 2004-03-26 2011-07-12 Qualcomm Incorporated Synchronous inter-piconet routing
US20060121055A1 (en) * 2004-12-06 2006-06-08 Becton, Dickinson And Company, Inc. Compositions with enhanced immunogenicity

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034801A2 (fr) * 1999-11-12 2001-05-17 Fibrogen, Inc. Vaccins contenant de la gelatine recombinante
WO2002074244A2 (fr) * 2001-03-19 2002-09-26 Iomai Corporation Immunostimulation transcutanee
WO2002087494A2 (fr) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals, Sa Nouveau vaccin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAKAYAMA ET AL: "A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY - YEARLY BOOK, INC, US, vol. 103, no. 2, 1 February 1999 (1999-02-01), pages 321 - 325, XP005687168, ISSN: 0091-6749 *

Also Published As

Publication number Publication date
WO2005074460A3 (fr) 2005-09-29
CA2548210A1 (fr) 2005-08-18
BRPI0417225A (pt) 2007-03-06
WO2005074460A9 (fr) 2006-08-24
US20090304744A1 (en) 2009-12-10
CN1905896A (zh) 2007-01-31
EP1708742A2 (fr) 2006-10-11
AU2004315509A1 (en) 2005-08-18
JP2007516968A (ja) 2007-06-28
US20050281832A1 (en) 2005-12-22
WO2005074460A2 (fr) 2005-08-18

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20060620

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: METHA, SHEETAL

Inventor name: MIKSZTA, JOHN

Inventor name: WOODLEY, WENDY, D.

Inventor name: ALARCON, JASON

Inventor name: DOLAN, KEVIN, G.

Inventor name: CAMPBELL, ROBERT

A4 Supplementary search report drawn up and despatched

Effective date: 20081007

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/12 20060101ALI20080930BHEP

Ipc: G01N 33/53 20060101ALI20080930BHEP

Ipc: A61K 47/00 20060101ALI20080930BHEP

Ipc: A61K 45/00 20060101ALI20080930BHEP

Ipc: A61K 39/00 20060101AFI20060815BHEP

17Q First examination report despatched

Effective date: 20081230

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20090710