EP1817444A4 - Proteingerüste und ihre verwendung - Google Patents

Proteingerüste und ihre verwendung

Info

Publication number
EP1817444A4
EP1817444A4 EP05857979A EP05857979A EP1817444A4 EP 1817444 A4 EP1817444 A4 EP 1817444A4 EP 05857979 A EP05857979 A EP 05857979A EP 05857979 A EP05857979 A EP 05857979A EP 1817444 A4 EP1817444 A4 EP 1817444A4
Authority
EP
European Patent Office
Prior art keywords
protein scaffolds
uses therof
therof
scaffolds
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP05857979A
Other languages
English (en)
French (fr)
Other versions
EP1817444A2 (de
Inventor
Willem P C Stemmer
Martin Vogt
Joost A Kolkman
Josh Silverman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Mountain View Inc
Original Assignee
Avidia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avidia Inc filed Critical Avidia Inc
Publication of EP1817444A2 publication Critical patent/EP1817444A2/de
Publication of EP1817444A4 publication Critical patent/EP1817444A4/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP05857979A 2004-11-16 2005-11-16 Proteingerüste und ihre verwendung Ceased EP1817444A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62859604P 2004-11-16 2004-11-16
PCT/US2005/041639 WO2006127040A2 (en) 2004-11-16 2005-11-16 Protein scaffolds and uses therof

Publications (2)

Publication Number Publication Date
EP1817444A2 EP1817444A2 (de) 2007-08-15
EP1817444A4 true EP1817444A4 (de) 2010-02-17

Family

ID=37452497

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05857979A Ceased EP1817444A4 (de) 2004-11-16 2005-11-16 Proteingerüste und ihre verwendung

Country Status (6)

Country Link
EP (1) EP1817444A4 (de)
JP (1) JP2008520208A (de)
AU (1) AU2005332022A1 (de)
CA (1) CA2587463A1 (de)
MX (1) MX2007005865A (de)
WO (1) WO2006127040A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005673A1 (en) 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
CA2360011A1 (en) 1999-01-05 2000-07-13 Trustees Of Boston University Ordered gene assembly
US7435562B2 (en) 2000-07-21 2008-10-14 Modular Genetics, Inc. Modular vector systems
CA2590245A1 (en) 2004-11-11 2006-05-18 Modular Genetics, Inc. Ladder assembly and system for generating diversity
AU2010226392B9 (en) 2009-03-20 2014-05-22 Amgen Inc. Selective and potent peptide inhibitors of Kv1.3
EA201370076A1 (ru) 2010-09-22 2013-08-30 Амген Инк. Иммуноглобулины-переносчики и их применение
KR20260008164A (ko) 2016-12-02 2026-01-15 바이오버라티브 테라퓨틱스 인크. 키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법
MA52630B1 (fr) 2018-05-18 2025-07-31 Bioverativ Therapeutics Inc. Procédés de traitement de l'hémophilie a

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004018995A2 (en) * 2002-08-23 2004-03-04 Williams Kevin J Thrombospondin fragments and uses thereof in clinical assays for cancer and generation of antibodies and other binding agents
WO2004044011A2 (en) * 2002-11-06 2004-05-27 Avidia Research Institute Combinatorial libraries of monomer domains

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE472609T1 (de) * 2001-04-26 2010-07-15 Amgen Mountain View Inc Kombinatorische bibliotheken von monomerdomänen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004018995A2 (en) * 2002-08-23 2004-03-04 Williams Kevin J Thrombospondin fragments and uses thereof in clinical assays for cancer and generation of antibodies and other binding agents
WO2004044011A2 (en) * 2002-11-06 2004-05-27 Avidia Research Institute Combinatorial libraries of monomer domains

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LAWLER J ET AL: "THE STRUCTURE OF HUMAN THROMBOSPONDIN, AN ADHESIVE GLYCOPROTEIN WITH MULTIPLE CALCIUM-BINDING SITES AND HOMOLOGIES WITH SEVERAL DIFFERENT PROTEINS", THE JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, US, vol. 103, 1 November 1986 (1986-11-01), pages 1635 - 1648, XP002932599, ISSN: 0021-9525 *

Also Published As

Publication number Publication date
JP2008520208A (ja) 2008-06-19
WO2006127040A2 (en) 2006-11-30
CA2587463A1 (en) 2006-11-30
WO2006127040A3 (en) 2009-04-09
MX2007005865A (es) 2008-02-25
EP1817444A2 (de) 2007-08-15
AU2005332022A1 (en) 2006-11-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070615

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK YU

DAX Request for extension of the european patent (deleted)
R17D Deferred search report published (corrected)

Effective date: 20090409

RIC1 Information provided on ipc code assigned before grant

Ipc: C12P 21/06 20060101ALI20090929BHEP

Ipc: C07K 1/00 20060101AFI20090929BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20100115

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/68 20060101ALI20100111BHEP

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