EP1820497A3 - Formulation de bisphosphonate effervescente - Google Patents

Formulation de bisphosphonate effervescente Download PDF

Info

Publication number
EP1820497A3
EP1820497A3 EP07009020A EP07009020A EP1820497A3 EP 1820497 A3 EP1820497 A3 EP 1820497A3 EP 07009020 A EP07009020 A EP 07009020A EP 07009020 A EP07009020 A EP 07009020A EP 1820497 A3 EP1820497 A3 EP 1820497A3
Authority
EP
European Patent Office
Prior art keywords
bisphosphonate formulation
effervescent
effervescent bisphosphonate
formulation
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07009020A
Other languages
German (de)
English (en)
Other versions
EP1820497A2 (fr
Inventor
Ashok V. Katdare
Kenneth A. Kramer
Colin R. Gardner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613183.4A external-priority patent/GB9613183D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority claimed from EP97924695A external-priority patent/EP0939624B1/fr
Priority claimed from EP03077124A external-priority patent/EP1378234A1/fr
Publication of EP1820497A2 publication Critical patent/EP1820497A2/fr
Publication of EP1820497A3 publication Critical patent/EP1820497A3/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP07009020A 1996-05-17 1997-05-13 Formulation de bisphosphonate effervescente Withdrawn EP1820497A3 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1788196P 1996-05-17 1996-05-17
GBGB9613183.4A GB9613183D0 (en) 1996-06-24 1996-06-24 Effervescent alendronate formulation
EP97924695A EP0939624B1 (fr) 1996-05-17 1997-05-13 Formulation de bisphosphonate efferverscente
EP03077124A EP1378234A1 (fr) 1996-05-17 1997-05-13 Formulation de bisphosphonate effervescente

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP03077124A Division EP1378234A1 (fr) 1996-05-17 1997-05-13 Formulation de bisphosphonate effervescente

Publications (2)

Publication Number Publication Date
EP1820497A2 EP1820497A2 (fr) 2007-08-22
EP1820497A3 true EP1820497A3 (fr) 2009-07-22

Family

ID=38279155

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07009020A Withdrawn EP1820497A3 (fr) 1996-05-17 1997-05-13 Formulation de bisphosphonate effervescente

Country Status (1)

Country Link
EP (1) EP1820497A3 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201110526A2 (tr) 2011-01-06 2012-07-23 Bi̇lgi̇ç Mahmut Kemik hastalıklarının tedavisinde kullanılmak üzere suda çözünebilir farmasötik formülasyonlar.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4621077A (en) * 1982-04-15 1986-11-04 Istituto Gentili S.P.A. Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom
EP0521388A1 (fr) * 1991-07-01 1993-01-07 Gerhard Dr. Gergely Procédé de préparation d'une composition pharmaceutique à base d'au mains deux principes actifs différents et utilisation d'une telle composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4621077A (en) * 1982-04-15 1986-11-04 Istituto Gentili S.P.A. Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom
EP0521388A1 (fr) * 1991-07-01 1993-01-07 Gerhard Dr. Gergely Procédé de préparation d'une composition pharmaceutique à base d'au mains deux principes actifs différents et utilisation d'une telle composition

Also Published As

Publication number Publication date
EP1820497A2 (fr) 2007-08-22

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