EP1841424A4 - Synthese d'aryl pyrrolidones - Google Patents

Synthese d'aryl pyrrolidones

Info

Publication number
EP1841424A4
EP1841424A4 EP06719887A EP06719887A EP1841424A4 EP 1841424 A4 EP1841424 A4 EP 1841424A4 EP 06719887 A EP06719887 A EP 06719887A EP 06719887 A EP06719887 A EP 06719887A EP 1841424 A4 EP1841424 A4 EP 1841424A4
Authority
EP
European Patent Office
Prior art keywords
synthesis
pyrrolidones
aryl
aryl pyrrolidones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06719887A
Other languages
German (de)
English (en)
Other versions
EP1841424A2 (fr
Inventor
Yun He
David Woodmanse
Ha-Soon Choi
Zhicheng Wang
Baogen Wu
Nguyen Truc Ngoc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRM LLC
Original Assignee
IRM LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRM LLC filed Critical IRM LLC
Publication of EP1841424A2 publication Critical patent/EP1841424A2/fr
Publication of EP1841424A4 publication Critical patent/EP1841424A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EP06719887A 2005-01-28 2006-01-30 Synthese d'aryl pyrrolidones Withdrawn EP1841424A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64803905P 2005-01-28 2005-01-28
PCT/US2006/003240 WO2006081562A2 (fr) 2005-01-28 2006-01-30 Synthese d'aryl pyrrolidones

Publications (2)

Publication Number Publication Date
EP1841424A2 EP1841424A2 (fr) 2007-10-10
EP1841424A4 true EP1841424A4 (fr) 2010-01-27

Family

ID=36741151

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06719887A Withdrawn EP1841424A4 (fr) 2005-01-28 2006-01-30 Synthese d'aryl pyrrolidones

Country Status (10)

Country Link
EP (1) EP1841424A4 (fr)
JP (1) JP2008528625A (fr)
KR (1) KR100890696B1 (fr)
CN (1) CN101111246A (fr)
AU (1) AU2006209241B2 (fr)
BR (1) BRPI0607294A2 (fr)
CA (1) CA2593816A1 (fr)
MX (1) MX2007008974A (fr)
RU (1) RU2007132260A (fr)
WO (1) WO2006081562A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102958927A (zh) 2010-05-12 2013-03-06 Abbvie公司 激酶的吲唑抑制剂
CN101979378B (zh) * 2010-10-13 2012-06-27 中国科学院上海有机化学研究所 一种手性γ-内酰胺化合物的合成方法
RU2485100C1 (ru) * 2012-02-07 2013-06-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" 1-арил-4-бензоил-3-гидрокси-5-метоксикарбонил-2,5-дигидро-1н-пиррол-2-оны, проявляющие анальгетическую активность, и способ их получения
MD4889C1 (ro) 2013-12-03 2024-10-31 Фмк Корпорейшн Pirolidinone în calitate de erbicide
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
WO2016003997A1 (fr) 2014-07-02 2016-01-07 E. I. Du Pont De Nemours And Company Herbicides de pipéridinone
JP6611816B2 (ja) 2014-12-08 2019-11-27 エフ エム シー コーポレーション ３−オキソ−３−（アリールアミノ）プロパノエイト、その製造方法、およびピロリジノンの製造におけるその使用
US10405547B2 (en) 2015-04-10 2019-09-10 Fmc Corporation Substituted cyclic amides as herbicides
EP3288928B1 (fr) 2015-04-27 2021-10-13 FMC Corporation Butyrolactones comme herbicides
CA2980643C (fr) 2015-05-12 2023-10-17 E I Du Pont De Nemours And Company Composes bicycliques substitues par un aryle a titre d'herbicides
CA2983590C (fr) 2015-05-29 2021-11-30 E I Du Pont De Nemours And Company Amides cycliques substitues utilises comme herbicides
JP6949730B2 (ja) 2015-06-02 2021-10-13 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 置換環状アミドおよび除草剤としてのそれらの使用
AU2016303209B2 (en) 2015-07-31 2021-04-01 Fmc Corporation Cyclic N-carboxamide compounds useful as herbicides
BR112019012910B1 (pt) 2016-12-21 2023-10-17 Fmc Corporation Composto, composição herbicida, mistura herbicida e método para controlar o crescimento de vegetação indesejável
SG11201908640TA (en) 2017-03-21 2019-10-30 Fmc Corp Pyrrolidinones and a process to prepare them
BR112019019551A2 (pt) 2017-03-21 2020-04-22 Fmc Corp mistura, e, método para controlar o crescimento de vegetação indesejada
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
CA3193554A1 (fr) * 2020-10-06 2022-04-14 D.E. Shaw Research, Llc Composes lactames utilises comme bloqueurs des canaux potassiques shaker kv1.3

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
WO2004037784A2 (fr) * 2002-10-21 2004-05-06 Irm Llc Pyrrolidones ayant une activité anti-vih
WO2006081554A2 (fr) * 2005-01-28 2006-08-03 Irm Llc Pyrrolidones a substitution phenyle

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058986A (en) 1962-10-16 N-ammoalkyl-x-phenyl-x-lower alkyl-z-
US3956914A (en) * 1974-11-14 1976-05-18 The Marison Company Spin lathe
JP2002363160A (ja) * 2001-06-05 2002-12-18 Sumitomo Chem Co Ltd 光学活性４−アリール−２−ピペリジノン類の製造方法
JP4351859B2 (ja) * 2003-04-14 2009-10-28 三菱レイヨン株式会社 光学活性β−アリ−ル化合物の製造法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
WO2004037784A2 (fr) * 2002-10-21 2004-05-06 Irm Llc Pyrrolidones ayant une activité anti-vih
WO2006081554A2 (fr) * 2005-01-28 2006-08-03 Irm Llc Pyrrolidones a substitution phenyle

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KEITH FAGNOU AND MARK LAUTENS: "Rhodium-catalyzed carbon-carbon bond forming reactions of organometallic compounds", CHEMICAL REVIEWS, vol. 103, no. 1, 2003, pages 169 - 196, XP002559949 *
MARK LAUTENS ET AL: "Rhodium-catalyzed Heck-type coupling of boronic acids with activated alkenes in an aqueous emulsion", SYNTHESIS, no. 12, 2004, pages 2006 - 2014, XP001205153, ISSN: 0039-7881 *
RYO SHINTANI ET AL: "Chiral norbornadienes as efficient ligands for the rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to fumaric and maleic compounds", ORGANIC LETTERS, vol. 6, no. 19, 2004, pages 3425 - 3427, XP002559905 *
TAICHI SENDA ET AL: "Rhodium-catalyzed asymmetric 1,4-addition of organoboron reagents to 5,6-dihydro-2(1H)-pyridinones. Asymmetric synthesis of 4-aryl-2-piperidinones", JOURNAL OF ORGANIC CHEMISTRY, vol. 66, no. 21, 2001, pages 6852 - 6856, XP002977097, ISSN: 0022-3263 *
TAMIO HAYASHI AND KAORI YAMASAKI: "Rhodium-catalyzed asymmetric 1,4-addition and its related asymmetric reactions", CHEMICAL REVIEWS, vol. 103, no. 8, 2003, pages 2829 - 2844, XP002559950 *

Also Published As

Publication number Publication date
KR100890696B1 (ko) 2009-03-26
AU2006209241A1 (en) 2006-08-03
CA2593816A1 (fr) 2006-08-03
JP2008528625A (ja) 2008-07-31
KR20070097555A (ko) 2007-10-04
RU2007132260A (ru) 2009-03-10
EP1841424A2 (fr) 2007-10-10
WO2006081562A2 (fr) 2006-08-03
CN101111246A (zh) 2008-01-23
WO2006081562A3 (fr) 2006-10-19
BRPI0607294A2 (pt) 2009-08-25
MX2007008974A (es) 2007-09-18
AU2006209241B2 (en) 2009-10-22

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