EP1848410A4 - Compositions d'administration particulaires, polymeriques, et leurs methodes d'utilisation - Google Patents
Compositions d'administration particulaires, polymeriques, et leurs methodes d'utilisationInfo
- Publication number
- EP1848410A4 EP1848410A4 EP06734169A EP06734169A EP1848410A4 EP 1848410 A4 EP1848410 A4 EP 1848410A4 EP 06734169 A EP06734169 A EP 06734169A EP 06734169 A EP06734169 A EP 06734169A EP 1848410 A4 EP1848410 A4 EP 1848410A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- administration compositions
- particulate polymeric
- polymeric administration
- particulate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
- C08L77/12—Polyester-amides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65471505P | 2005-02-17 | 2005-02-17 | |
| US68467005P | 2005-05-25 | 2005-05-25 | |
| US68757005P | 2005-06-03 | 2005-06-03 | |
| US71995005P | 2005-09-22 | 2005-09-22 | |
| US73740105P | 2005-11-14 | 2005-11-14 | |
| US75917906P | 2006-01-13 | 2006-01-13 | |
| PCT/US2006/003575 WO2006088647A1 (fr) | 2005-02-17 | 2006-01-31 | Compositions d'administration particulaires, polymeriques, et leurs methodes d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1848410A1 EP1848410A1 (fr) | 2007-10-31 |
| EP1848410A4 true EP1848410A4 (fr) | 2011-11-09 |
Family
ID=36916776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP06734169A Withdrawn EP1848410A4 (fr) | 2005-02-17 | 2006-01-31 | Compositions d'administration particulaires, polymeriques, et leurs methodes d'utilisation |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1848410A4 (fr) |
| JP (1) | JP2008530206A (fr) |
| CN (1) | CN101115471B (fr) |
| AU (1) | AU2006214655A1 (fr) |
| CA (1) | CA2596011C (fr) |
| WO (1) | WO2006088647A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
| CA2623198C (fr) | 2005-09-22 | 2014-08-05 | Medivas, Llc | Formules de poly(ester amide) et de poly(ester urethane) contenant des diesters de bis-(a-amino)-diol et methodes d'emploi |
| JP5178520B2 (ja) | 2005-09-22 | 2013-04-10 | メディバス エルエルシー | 固体ポリマー送達組成物およびその使用法 |
| WO2007112046A2 (fr) * | 2006-03-24 | 2007-10-04 | Medivas, Llc | Poly(ester amides) biodegradables contenant du dicarboxylate d'alkylene et leurs methodes d'utilisation |
| US8658210B2 (en) * | 2006-04-17 | 2014-02-25 | Advanced Cardiovascular Systems, Inc. | Polyesteramide platform for site specific drug delivery |
| WO2007133616A2 (fr) * | 2006-05-09 | 2007-11-22 | Medivas, Llc | Polymères hydrosolubles biodégradables |
| WO2008082721A2 (fr) * | 2006-09-05 | 2008-07-10 | Medivas, Llc | Compositions liposomales stabilisées par des polymères et leurs méthodes d'utilisation |
| US20090068743A1 (en) * | 2007-08-23 | 2009-03-12 | Medivas, Llc | Cationic alpha-amino acid-containing biodegradable polymer gene transfer compositions |
| EP2282720B1 (fr) * | 2008-05-15 | 2013-09-11 | Biocompatibles Uk Ltd. | Libération intracellulaire d'anticorps |
| CA2736393A1 (fr) * | 2008-10-15 | 2010-04-22 | Medivas, Llc | Polymeres biodegradables a base de proline |
| ES2992024T3 (es) | 2011-06-23 | 2024-12-05 | Dsm Ip Assets Bv | Nuevos copolímeros de poliesteramida biodegradables para la administración de fármacos |
| US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
| US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
| WO2016207725A1 (fr) * | 2015-06-23 | 2016-12-29 | Phagelux (Canada), Inc. | Composition comprenant des polymères d'acide aminé et un agent bioactif et procédé de préparation associé |
| CN110023407B (zh) * | 2016-09-20 | 2021-10-29 | 康奈尔大学 | 标记的聚(酯酰胺氨基甲酸酯)、由其形成的纳米粒子和其用途 |
| KR20210151822A (ko) * | 2019-03-14 | 2021-12-14 | 엔진 인코포레이티드 | 키토산-핵산 나노입자의 가역성 코팅 및 이의 사용 방법 |
| CA3160955A1 (fr) * | 2019-11-12 | 2021-05-20 | Dsm Ip Assets B.V. | Copolymeres de polyesteramides possedant une temperature de transition vitreuse elevee |
| CN112321822B (zh) * | 2020-12-02 | 2021-12-10 | 中山大学 | 一种具有ros响应性的蛋氨酸-聚酯酰胺高分子聚合物及其应用 |
| CN114920869B (zh) * | 2022-05-24 | 2023-07-14 | 太原工业学院 | 两亲性精氨酸嵌段环丙沙星共聚物、纳米颗粒及其制备方法和应用 |
| CN119039583B (zh) * | 2024-11-01 | 2025-03-11 | 浙江农林大学 | 一种具有立构复合结晶性能侧链碱基生物可降解聚酯酰胺及其酶促制备方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5449513A (en) * | 1992-08-14 | 1995-09-12 | Research Development Corporation Of Japan | Physical trapping type polymeric micelle drug preparation |
| US5861387A (en) * | 1991-06-28 | 1999-01-19 | Endorecherche Inc. | Controlled release systems and low dose androgens |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US20020015720A1 (en) * | 2000-01-11 | 2002-02-07 | Ramaz Katsarava | Polymer blends as biodegradable matrices for preparing biocomposites |
| WO2003062298A1 (fr) * | 2002-01-17 | 2003-07-31 | Polyrava Llc | Co-poly(ester amide) et co-poly(ester urethane) compositions presentant une biodegradabilite, procedes de production et utilisation associes |
| WO2004039944A2 (fr) * | 2002-05-15 | 2004-05-13 | Rutgers, The State University | Polymeres triblocs pour administration de gene ou de medicament a base de nanospheres |
| EP1945682A2 (fr) * | 2005-10-21 | 2008-07-23 | Medivas, LLC | Polymeres de poly(ester-uree) et leurs procedes d'utilisation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164374A1 (en) * | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
| BR9813548A (pt) * | 1997-12-12 | 2000-10-10 | Samyang Corp | Micelas poliméricas misturadas biodegradáveis para distribuição de gene |
| CN1339964A (zh) * | 1999-02-19 | 2002-03-13 | 生化研究股份公司 | 用以生产微胶囊的生物可降解复合材料 |
| ATE313341T1 (de) * | 2000-01-11 | 2006-01-15 | Intralytix Inc | Polymermischungen als bioabbaubare matrizen zur herstellung von biokompositen |
| CA2397404C (fr) * | 2000-01-14 | 2008-12-02 | Brown University Research Foundation | Particules lyophilisees microfines |
| FR2811227A1 (fr) * | 2000-07-07 | 2002-01-11 | Philippe Maincent | Vecteurs particulaires destines a ameliorer l'absorption orale de principes actifs |
| US6503538B1 (en) * | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
| CN1119172C (zh) * | 2000-12-12 | 2003-08-27 | 天津大学 | 脂肪族聚酯表面的壳聚糖/明胶网络修饰方法 |
| US20050152980A1 (en) * | 2002-03-13 | 2005-07-14 | Michael Ausborn | Pharmeutical microparticles |
| WO2003092585A2 (fr) * | 2002-05-02 | 2003-11-13 | Pr Pharmaceuticals, Inc. | Compositions a liberation regulee de metabolites d'estradiol |
| CN101044638B (zh) * | 2004-10-18 | 2012-05-09 | 株式会社明电舍 | 帕尔帖元件或塞贝克元件的结构及其制造方法 |
-
2006
- 2006-01-31 WO PCT/US2006/003575 patent/WO2006088647A1/fr not_active Ceased
- 2006-01-31 CN CN200680004221XA patent/CN101115471B/zh not_active Expired - Fee Related
- 2006-01-31 CA CA2596011A patent/CA2596011C/fr not_active Expired - Lifetime
- 2006-01-31 EP EP06734169A patent/EP1848410A4/fr not_active Withdrawn
- 2006-01-31 AU AU2006214655A patent/AU2006214655A1/en not_active Abandoned
- 2006-01-31 JP JP2007556163A patent/JP2008530206A/ja active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861387A (en) * | 1991-06-28 | 1999-01-19 | Endorecherche Inc. | Controlled release systems and low dose androgens |
| US5449513A (en) * | 1992-08-14 | 1995-09-12 | Research Development Corporation Of Japan | Physical trapping type polymeric micelle drug preparation |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US20020015720A1 (en) * | 2000-01-11 | 2002-02-07 | Ramaz Katsarava | Polymer blends as biodegradable matrices for preparing biocomposites |
| WO2003062298A1 (fr) * | 2002-01-17 | 2003-07-31 | Polyrava Llc | Co-poly(ester amide) et co-poly(ester urethane) compositions presentant une biodegradabilite, procedes de production et utilisation associes |
| WO2004039944A2 (fr) * | 2002-05-15 | 2004-05-13 | Rutgers, The State University | Polymeres triblocs pour administration de gene ou de medicament a base de nanospheres |
| EP1945682A2 (fr) * | 2005-10-21 | 2008-07-23 | Medivas, LLC | Polymeres de poly(ester-uree) et leurs procedes d'utilisation |
Non-Patent Citations (2)
| Title |
|---|
| ARABULI N ET AL: "HETEROCHAIN POLYMERS BASED ON NATURAL AMINO ACIDS. SYNTHESIS AND ENZYMATIC HYDROLYSIS OF REGULAR POL(ESTER AMIDE)S BASED ON BIS(L-PHENYLALANINE)ALPHA,OMEGA-ALKYLENE DIESTERS AND ADIPIC ACID", MACROMOLECULAR CHEMISTRY AND PHYSICS, WILEY-VCH VERLAG, WEINHEIM, DE, vol. 195, no. 6, 1 January 1994 (1994-01-01), pages 2279 - 2289, XP002171341, ISSN: 1022-1352, DOI: 10.1002/MACP.1994.021950633 * |
| See also references of WO2006088647A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101115471B (zh) | 2011-02-09 |
| CN101115471A (zh) | 2008-01-30 |
| CA2596011C (fr) | 2013-05-14 |
| EP1848410A1 (fr) | 2007-10-31 |
| CA2596011A1 (fr) | 2006-08-24 |
| JP2008530206A (ja) | 2008-08-07 |
| WO2006088647A1 (fr) | 2006-08-24 |
| AU2006214655A1 (en) | 2006-08-24 |
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