EP1856072A4 - Thiazolderivate als ppar-delta-liganden und verfahren zu ihrer herstellung - Google Patents

Thiazolderivate als ppar-delta-liganden und verfahren zu ihrer herstellung

Info

Publication number
EP1856072A4
EP1856072A4 EP06716113A EP06716113A EP1856072A4 EP 1856072 A4 EP1856072 A4 EP 1856072A4 EP 06716113 A EP06716113 A EP 06716113A EP 06716113 A EP06716113 A EP 06716113A EP 1856072 A4 EP1856072 A4 EP 1856072A4
Authority
EP
European Patent Office
Prior art keywords
preparation
ppar delta
delta ligands
thiazone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06716113A
Other languages
English (en)
French (fr)
Other versions
EP1856072A1 (de
Inventor
Jungyeob Ham
Hoosang Hwang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seoul National University Industry Foundation
Original Assignee
Seoul National University Industry Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seoul National University Industry Foundation filed Critical Seoul National University Industry Foundation
Priority claimed from KR1020060018360A external-priority patent/KR100797798B1/ko
Publication of EP1856072A1 publication Critical patent/EP1856072A1/de
Publication of EP1856072A4 publication Critical patent/EP1856072A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
EP06716113A 2005-02-25 2006-02-24 Thiazolderivate als ppar-delta-liganden und verfahren zu ihrer herstellung Withdrawn EP1856072A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20050015663 2005-02-25
PCT/KR2006/000663 WO2006091047A1 (en) 2005-02-25 2006-02-24 Thiazole derivatives as ppar delta ligands and their manufacturing process
KR1020060018360A KR100797798B1 (ko) 2005-02-25 2006-02-24 퍼록시솜 증식자 활성화 수용체 델타 리간드 티아졸 유도체및 그의 제조방법

Publications (2)

Publication Number Publication Date
EP1856072A1 EP1856072A1 (de) 2007-11-21
EP1856072A4 true EP1856072A4 (de) 2009-10-21

Family

ID=36927652

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06716113A Withdrawn EP1856072A4 (de) 2005-02-25 2006-02-24 Thiazolderivate als ppar-delta-liganden und verfahren zu ihrer herstellung

Country Status (3)

Country Link
EP (1) EP1856072A4 (de)
CA (1) CA2599281C (de)
WO (1) WO2006091047A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8519145B2 (en) 2006-12-02 2013-08-27 Seoul National University Industry Foundation Aryl compounds as PPAR ligands and their use
BRPI0807023A2 (pt) * 2007-01-08 2014-04-22 Seoul Nat Univ Ind Foundation Composto de tiazol como ligante de ppard e produto farmacêutico, cosmético e alimento saudável dele composto
CN102781924A (zh) * 2010-02-25 2012-11-14 首尔大学校产学协力财团 用作过氧化物酶体增殖剂激活受体的配体的硒唑衍生物、其制备方法及其化合物的用途
CN103298469A (zh) 2010-08-31 2013-09-11 首尔大学校产学协力财团 PPARδ激动剂的胎儿重编程的用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062774A1 (en) * 2000-12-20 2002-08-15 Glaxo Group Limited Thiazole derivatives for treating ppar related disorders
WO2003072100A1 (en) * 2002-02-25 2003-09-04 Eli Lilly And Company Peroxisome proliferator activated receptor modulators
WO2003106442A1 (en) * 2002-05-04 2003-12-24 Heonjoong Kang Process for preparing thiazole derivative and the intermediate compounds for preparing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000001679A1 (en) * 1998-07-01 2000-01-13 Takeda Chemical Industries, Ltd. Retinoid-associated receptor regulators
HUP0200807A3 (en) * 1999-04-20 2003-03-28 Novo Nordisk As Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062774A1 (en) * 2000-12-20 2002-08-15 Glaxo Group Limited Thiazole derivatives for treating ppar related disorders
WO2003072100A1 (en) * 2002-02-25 2003-09-04 Eli Lilly And Company Peroxisome proliferator activated receptor modulators
WO2003106442A1 (en) * 2002-05-04 2003-12-24 Heonjoong Kang Process for preparing thiazole derivative and the intermediate compounds for preparing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006091047A1 *

Also Published As

Publication number Publication date
CA2599281C (en) 2012-01-17
EP1856072A1 (de) 2007-11-21
WO2006091047A1 (en) 2006-08-31
CA2599281A1 (en) 2006-08-31

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION

A4 Supplementary search report drawn up and despatched

Effective date: 20090921

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 3/10 20060101ALI20090915BHEP

Ipc: A61P 3/06 20060101ALI20090915BHEP

Ipc: A61K 31/426 20060101ALI20090915BHEP

Ipc: C07D 277/26 20060101AFI20060904BHEP

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Effective date: 20091215

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Effective date: 20140410

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Inventor name: HWANG, HOOSANG

Inventor name: HAM, JUNGYEOB

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20140821