EP1879608A4 - Methode pour stimuler la formation et la preservation des os - Google Patents

Methode pour stimuler la formation et la preservation des os

Info

Publication number
EP1879608A4
EP1879608A4 EP05851371A EP05851371A EP1879608A4 EP 1879608 A4 EP1879608 A4 EP 1879608A4 EP 05851371 A EP05851371 A EP 05851371A EP 05851371 A EP05851371 A EP 05851371A EP 1879608 A4 EP1879608 A4 EP 1879608A4
Authority
EP
European Patent Office
Prior art keywords
preservation
promoting bone
training
bone training
promoting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP05851371A
Other languages
German (de)
English (en)
Other versions
EP1879608A1 (fr
Inventor
Agnes Vignery
Nozer M Mehta
James P Gilligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Unigene Laboratories Inc
Original Assignee
Yale University
Unigene Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/128,095 external-priority patent/US7531518B2/en
Application filed by Yale University, Unigene Laboratories Inc filed Critical Yale University
Publication of EP1879608A1 publication Critical patent/EP1879608A1/fr
Publication of EP1879608A4 publication Critical patent/EP1879608A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/225—Calcitonin gene related peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP05851371A 2005-05-11 2005-11-07 Methode pour stimuler la formation et la preservation des os Ceased EP1879608A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/128,095 US7531518B2 (en) 2004-05-14 2005-05-11 Method for fostering bone formation and preservation
PCT/US2005/040032 WO2006124062A1 (fr) 2005-05-11 2005-11-07 Methode pour stimuler la formation et la preservation des os

Publications (2)

Publication Number Publication Date
EP1879608A1 EP1879608A1 (fr) 2008-01-23
EP1879608A4 true EP1879608A4 (fr) 2009-11-11

Family

ID=37431531

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05851371A Ceased EP1879608A4 (fr) 2005-05-11 2005-11-07 Methode pour stimuler la formation et la preservation des os

Country Status (5)

Country Link
EP (1) EP1879608A4 (fr)
JP (1) JP2008540522A (fr)
CN (1) CN101217972B (fr)
CA (1) CA2608016A1 (fr)
WO (1) WO2006124062A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101663043B (zh) * 2007-04-27 2014-03-12 尤尼基因实验室公司 促进和保持骨生长的方法和组合物
JP5320183B2 (ja) * 2008-06-26 2013-10-23 国立大学法人 岡山大学 顎顔面インプラント治療のための骨質検査方法
WO2019094617A1 (fr) * 2017-11-09 2019-05-16 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Cellules souches et dispositifs de régénération osseuse

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003039331A2 (fr) * 2001-11-05 2003-05-15 Eli Lilly And Company Procede servant a ameliorer la stabilite d'un implant de liaison osseuse
WO2005112864A2 (fr) * 2004-05-14 2005-12-01 Unigene Laboratories, Inc. Procede permettant de favoriser la formation et la conservation osseuses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376476B1 (en) * 1996-12-13 2002-04-23 Zymogenetics Corporation Isoprenoid pathway inhibitors for stimulating bone growth
DZ2873A1 (fr) * 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003039331A2 (fr) * 2001-11-05 2003-05-15 Eli Lilly And Company Procede servant a ameliorer la stabilite d'un implant de liaison osseuse
WO2005112864A2 (fr) * 2004-05-14 2005-12-01 Unigene Laboratories, Inc. Procede permettant de favoriser la formation et la conservation osseuses

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 15 December 2000 (2000-12-15), VILLA ISABELLA ET AL: "Effects of calcitonin gene-related peptide and amylin on human osteoblast-like cells proliferation", Database accession no. PREV200100048784 *
HORWITZ MARA J ET AL: "Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, THE ENDOCRINE SOCIETY, US, vol. 88, no. 2, 1 February 2003 (2003-02-01), pages 569 - 575, XP002530462, ISSN: 0021-972X, DOI: 10.1210/JC.2002-021122 *
HUNZIKER J ET AL: "Mandibular bone formation rates in aged ovariectomized rats treated with anti-resorptive agents alone and in combination with intermittent parathyroid hormone", JOURNAL OF DENTAL RESEARCH, vol. 79, no. 6, June 2000 (2000-06-01), pages 1431 - 1438, XP002533456, ISSN: 0022-0345 *
KOBAYASHI S ET AL: "Advantages of concurrent use of anabolic and antiresorptive agents over single use of these agents in increasing trabecular bone volume, connectivity, and biomechanical competence of rat vertebrae.", BONE DEC 1999, vol. 25, no. 6, December 1999 (1999-12-01), pages 703 - 712, XP002533459, ISSN: 8756-3282 *
See also references of WO2006124062A1 *
SKRIPITZ ET AL: "Implant fixation enhanced by intermittent treatment with parathyroid hormone", JOURNAL OF BONE AND JOINT SURGERY. BRITISH VOLUME, LIVINGSTONE, LONDON, GB, vol. 83-B, no. 3, 1 April 2001 (2001-04-01), pages 437 - 440, XP002963350, ISSN: 0301-620X *
SKRIPITZ R ET AL: "Strong effect of PTH (1-34) on regenerating bone: A time sequence study in rats", ACTA ORTHOPAEDICA SCANDINAVICA, MUNKSGAARD, COPENHAGEN, DK, vol. 71, no. 6, 1 December 2000 (2000-12-01), pages 619 - 624, XP002319215, ISSN: 0001-6470 *
STEWART A F ET AL: "Six-month daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: A comparison of human parathyroid hormone 1-34, parathyroid hormone-related protein 1-36, and SDZ-parathyroid", JOURNAL OF BONE AND MINERAL RESEARCH, AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH, NEW YORK, NY, US, vol. 15, no. 8, 1 August 2000 (2000-08-01), pages 1517 - 1525, XP002530376, ISSN: 0884-0431, DOI: 10.1359/JBMR.2000.15.8.1517 *
TANAKA H ET AL: "Effect of IGF-I and PDGF administered in vivo on the expression of osteoblast-related genes in old rats", JOURNAL OF ENDOCRINOLOGY, vol. 174, no. 1, July 2002 (2002-07-01), pages 63 - 70, XP002533460, ISSN: 0022-0795 *
VILLA ISABELLA ET AL: "Effects of calcitonin gene-related peptide and amylin on human osteoblast-like cells proliferation", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 409, no. 3, 15 December 2000 (2000-12-15), pages 273 - 278, ISSN: 0014-2999 *

Also Published As

Publication number Publication date
WO2006124062A1 (fr) 2006-11-23
CN101217972B (zh) 2013-05-29
CN101217972A (zh) 2008-07-09
EP1879608A1 (fr) 2008-01-23
JP2008540522A (ja) 2008-11-20
CA2608016A1 (fr) 2006-11-23

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